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428 results

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Page 1
Alpha-zearalenol negatively influences ram sperm parameters during liquid storage.
Abbaszadeh S, Farrokhi-Ardabili F, Malekinejad H, Bernousi I. Abbaszadeh S, et al. Vet Res Forum. 2018 Spring;9(2):171-178. doi: 10.30466/VRF.2018.30823. Epub 2018 Jun 15. Vet Res Forum. 2018. PMID: 30065806 Free PMC article. Review.
This study was aimed to investigate the effects of 17 -estradiol (E2) and -zearalenol (alpha-ZOL) on motility parameters, plasma membrane integrity, levels of produced nitric oxide (NO) and total antioxidant capacity of Ghezel ram sperm during the liquid storage …
This study was aimed to investigate the effects of 17 -estradiol (E2) and -zearalenol (alpha-ZOL) on motility parameters, …
Interaction of mycotoxins zearalenone, alpha-zearalenol, and beta-zearalenol with cytochrome P450 (CYP1A2, 2C9, 2C19, 2D6, and 3A4) enzymes and organic anion transporting polypeptides (OATP1A2, OATP1B1, OATP1B3, and OATP2B1).
Kaci H, Dombi Á, Gömbös P, Szabó A, Bakos É, Özvegy-Laczka C, Poór M. Kaci H, et al. Toxicol In Vitro. 2024 Apr;96:105789. doi: 10.1016/j.tiv.2024.105789. Epub 2024 Feb 8. Toxicol In Vitro. 2024. PMID: 38341109 Free article.
The major reduced metabolites of ZEN are alpha-zearalenol (alpha-ZEL) and beta-zearalenol (beta-ZEL). Since the toxicokinetic interactions of ZEN/ZELs with cytochrome P450 enzymes (CYPs) and organic anion transporting polypeptides (OATPs) have been barely cha …
The major reduced metabolites of ZEN are alpha-zearalenol (alpha-ZEL) and beta-zearalenol (beta-ZEL). Since the toxicok …
Toxicokinetics of alpha-zearalenol and its masked form in rats and the comparative biotransformation in liver microsomes from different livestock and humans.
Yang S, Li Y, De Boevre M, De Saeger S, Zhou J, Li Y, Zhang H, Sun F. Yang S, et al. J Hazard Mater. 2020 Jul 5;393:121403. doi: 10.1016/j.jhazmat.2019.121403. Epub 2019 Oct 7. J Hazard Mater. 2020. PMID: 32143155
Alpha-zearalenol (alpha-ZEL) and its masked form alpha-zearalenol-14 glucoside (alpha-ZEL-14G) have much higher oestrogenic activity than zearalenone. ...
Alpha-zearalenol (alpha-ZEL) and its masked form alpha-zearalenol-14 glucoside (alpha-ZEL-14G) have much …
Effects of alpha-zearalenol on the metabolome of two breast cancer cell lines by 1H-NMR approach.
Nittoli AC, Costantini S, Sorice A, Capone F, Ciarcia R, Marzocco S, Budillon A, Severino L. Nittoli AC, et al. Metabolomics. 2018 Feb 14;14(3):33. doi: 10.1007/s11306-018-1330-3. Metabolomics. 2018. PMID: 30830360
INTRODUCTION: Zearalenone (ZEN) is one of the most widely distributed toxins that contaminates many crops and foods. Its major metabolites are alpha-Zearalenol (alpha-zol) and beta-Zearalenol. Previous studies showed that ZEN and alpha-zol have estrogenic pro …
INTRODUCTION: Zearalenone (ZEN) is one of the most widely distributed toxins that contaminates many crops and foods. Its major metabolites a …
Estrogenic activity of zearalenone, alpha-zearalenol and beta-zearalenol assessed using the E-screen assay in MCF-7 cells.
Tatay E, Espín S, García-Fernández AJ, Ruiz MJ. Tatay E, et al. Toxicol Mech Methods. 2018 May;28(4):239-242. doi: 10.1080/15376516.2017.1395501. Epub 2017 Nov 10. Toxicol Mech Methods. 2018. PMID: 29057713
They can enter the food chain and cause several health disorders. ZEA and its derivatives (alpha-zearalenol, alpha-ZOL and beta-zearalenol, beta-ZOL) have structural analogy to estrogen, thus they can bind to estrogen receptors (ERs). ...
They can enter the food chain and cause several health disorders. ZEA and its derivatives (alpha-zearalenol, alpha-ZOL …
Cytoprotective, Antiproliferative, and Anti-Oxidant Potential of the Hydroethanolic Extract of Fridericia chica Leaves on Human Cancer Cell Lines Exposed to α- and β-Zearalenol.
Alvarez-Ortega N, Caballero-Gallardo K, Juan C, Juan-Garcia A, Olivero-Verbel J. Alvarez-Ortega N, et al. Toxins (Basel). 2023 Jan 3;15(1):36. doi: 10.3390/toxins15010036. Toxins (Basel). 2023. PMID: 36668856 Free PMC article.
Fridericia chica (Bignoniaceae) is a Colombian Caribbean plant with numerous health benefits, including properties such as wound healing, immune system stimulation, and antioxidant capacity, among others. Mycotoxins alpha-zearalenol (alpha-ZEL) and beta-zeara …
Fridericia chica (Bignoniaceae) is a Colombian Caribbean plant with numerous health benefits, including properties such as wound healing, im …
Study of Competitive Displacement of Curcumin on alpha-zearalenol Binding to Human Serum Albumin Complex Using Fluorescence Spectroscopy.
Li Y, Tan H, Zhou H, Guo T, Zhou Y, Zhang Y, Liu X, Ma L. Li Y, et al. Toxins (Basel). 2022 Aug 31;14(9):604. doi: 10.3390/toxins14090604. Toxins (Basel). 2022. PMID: 36136542 Free PMC article.
alpha-zearalenol (alpha-ZOL) is a mycotoxin with a strong estrogen effect that affects the synthesis and secretion of sex hormones and is transported to target organs through human serum albumin (HSA). ...
alpha-zearalenol (alpha-ZOL) is a mycotoxin with a strong estrogen effect that affects the synthesis and secretion of s …
Estrogen receptor alpha interaction of zearalenone and its phase I metabolite alpha-zearalenol in combination with soy isoflavones in hERalpha-HeLa-9903 cells.
Grgic D, Novak B, Varga E, Marko D. Grgic D, et al. Mycotoxin Res. 2024 Feb;40(1):97-109. doi: 10.1007/s12550-023-00506-1. Epub 2023 Oct 17. Mycotoxin Res. 2024. PMID: 37847468 Free PMC article.
The mycoestrogens, zearalenone (ZEN), and alpha-zearalenol (alpha-ZEL) exhibited significantly enhanced estrogenic responses in the presence of isoflavones (ISF), depending on substance ratios and concentrations. ...
The mycoestrogens, zearalenone (ZEN), and alpha-zearalenol (alpha-ZEL) exhibited significantly enhanced estrogenic resp …
Mycotoxin alpha-zearalenol impairs the quality of preimplantation porcine embryos.
Wang H, Camargo Rodriguez O, Memili E. Wang H, et al. J Reprod Dev. 2012;58(3):338-43. doi: 10.1262/jrd.11-113h. Epub 2012 Mar 9. J Reprod Dev. 2012. PMID: 22447324 Free article.
Alpha-Zearalenol (alpha-ZEA) is one of derivatives from Zearalenone (ZEA) which impacts mammalian reproduction and development. ...
Alpha-Zearalenol (alpha-ZEA) is one of derivatives from Zearalenone (ZEA) which impacts mammalian reproduction and deve …
428 results