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A conserved viral amphipathic helix governs the replication site-specific membrane association.
Sathanantham P, Zhao W, He G, Murray A, Fenech E, Diaz A, Schuldiner M, Wang X. Sathanantham P, et al. PLoS Pathog. 2022 Sep 1;18(9):e1010752. doi: 10.1371/journal.ppat.1010752. eCollection 2022 Sep. PLoS Pathog. 2022. PMID: 36048900 Free PMC article.
We further show that an equivalent helix in several plant- and human-infecting viruses of the Alsuviricetes class targets fluorescent proteins to the organelle membranes where they form their VRCs, including ER, vacuole, and Golgi membranes. ...
We further show that an equivalent helix in several plant- and human-infecting viruses of the Alsuviricetes class targets fluorescent …
Doubling of the known set of RNA viruses by metagenomic analysis of an aquatic virome.
Wolf YI, Silas S, Wang Y, Wu S, Bocek M, Kazlauskas D, Krupovic M, Fire A, Dolja VV, Koonin EV. Wolf YI, et al. Nat Microbiol. 2020 Oct;5(10):1262-1270. doi: 10.1038/s41564-020-0755-4. Epub 2020 Jul 20. Nat Microbiol. 2020. PMID: 32690954 Free PMC article.
The 719-member-strong Yangshan virus assemblage is the sister clade to the expansive class Alsuviricetes and consists of viruses with simple genomes that typically encode only RNA-dependent RNA polymerase (RdRP), capping enzyme and capsid protein. ...
The 719-member-strong Yangshan virus assemblage is the sister clade to the expansive class Alsuviricetes and consists of viruses with …