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Quoted phrase not found in phrase index: "angelo d'alessandro"
Page 1
Specialized interferon action in COVID-19.
Galbraith MD, Kinning KT, Sullivan KD, Araya P, Smith KP, Granrath RE, Shaw JR, Baxter R, Jordan KR, Russell S, Dzieciatkowska M, Reisz JA, Gamboni F, Cendali F, Ghosh T, Guo K, Wilson CC, Santiago ML, Monte AA, Bennett TD, Hansen KC, Hsieh EWY, D'Alessandro A, Espinosa JM. Galbraith MD, et al. Among authors: d alessandro a. Proc Natl Acad Sci U S A. 2022 Mar 15;119(11):e2116730119. doi: 10.1073/pnas.2116730119. Proc Natl Acad Sci U S A. 2022. PMID: 35217532 Free PMC article.
The impacts of interferon (IFN) signaling on COVID-19 pathology are multiple, with both protective and harmful effects being documented. ...Altogether, these results reveal specialized IFN action in COVID-19, with potential diagnostic and therapeutic i …
The impacts of interferon (IFN) signaling on COVID-19 pathology are multiple, with both protective and harmful effects being d …
The COVIDome Explorer researcher portal.
Sullivan KD, Galbraith MD, Kinning KT, Bartsch KW, Levinsky NC, Araya P, Smith KP, Granrath RE, Shaw JR, Baxter RM, Jordan KR, Russell SA, Dzieciatkowska ME, Reisz JA, Gamboni F, Cendali FI, Ghosh T, Monte AA, Bennett TD, Miller MG, Hsieh EW, D'Alessandro A, Hansen KC, Espinosa JM. Sullivan KD, et al. Among authors: d alessandro a. Cell Rep. 2021 Aug 17;36(7):109527. doi: 10.1016/j.celrep.2021.109527. Epub 2021 Jul 28. Cell Rep. 2021. PMID: 34348131 Free PMC article.
COVID-19 pathology involves dysregulation of diverse molecular, cellular, and physiological processes. To expedite integrated and collaborative COVID-19 research, we completed multi-omics analysis of hospitalized COVID-19 patients, includ …
COVID-19 pathology involves dysregulation of diverse molecular, cellular, and physiological processes. To expedite integrated …
The COVIDome Explorer Researcher Portal.
Sullivan KD, Galbraith MD, Kinning KT, Bartsch K, Levinsky N, Araya P, Smith KP, Granrath RE, Shaw JR, Baxter R, Jordan KR, Russell S, Dzieciatkowska M, Reisz JA, Gamboni F, Cendali F, Ghosh T, Monte AA, Bennett TD, Miller MG, Hsieh EWY, D'Alessandro A, Hansen KC, Espinosa JM. Sullivan KD, et al. Among authors: d alessandro a. medRxiv [Preprint]. 2021 Mar 8:2021.03.04.21252945. doi: 10.1101/2021.03.04.21252945. medRxiv. 2021. Update in: Cell Rep. 2021 Aug 17;36(7):109527. doi: 10.1016/j.celrep.2021.109527. PMID: 33758879 Free PMC article. Updated. Preprint.
COVID-19 pathology involves dysregulation of diverse molecular, cellular, and physiological processes. In order to expedite integrated and collaborative COVID-19 research, we completed multi-omics analysis of hospitalized COVID-19 patient …
COVID-19 pathology involves dysregulation of diverse molecular, cellular, and physiological processes. In order to expedite in …
Coagulation potential and the integrated omics of extracellular vesicles from COVID-19 positive patient plasma.
Setua S, Thangaraju K, Dzieciatkowska M, Wilkerson RB, Nemkov T, Lamb DR, Tagaya Y, Boyer T, Rowden T, Doctor A, D'Alessandro A, Buehler PW. Setua S, et al. Among authors: d alessandro a. Sci Rep. 2022 Dec 23;12(1):22191. doi: 10.1038/s41598-022-26473-8. Sci Rep. 2022. PMID: 36564503 Free PMC article.
The role of EVs in COVID-19 related hemostasis may depend on cells of origin, vesicular cargo and size, however this is not well defined. We hypothesized that the procoagulant potential of EV isolates from COVID-19 (+) patient plasmas could be defined …
The role of EVs in COVID-19 related hemostasis may depend on cells of origin, vesicular cargo and size, however this is not we …
Cross-talk between red blood cells and plasma influences blood flow and omics phenotypes in severe COVID-19.
Recktenwald SM, Simionato G, Lopes MGM, Gamboni F, Dzieciatkowska M, Meybohm P, Zacharowski K, von Knethen A, Wagner C, Kaestner L, D'Alessandro A, Quint S. Recktenwald SM, et al. Among authors: d alessandro a. Elife. 2022 Dec 20;11:e81316. doi: 10.7554/eLife.81316. Elife. 2022. PMID: 36537079 Free PMC article.
Coronavirus disease 2019 (COVID-19) is caused by the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) and can affect multiple organs, among which is the circulatory system. ...We find …
Coronavirus disease 2019 (COVID-19) is caused by the Severe Acute Respiratory Syndrome C …
COVID-19 infection alters kynurenine and fatty acid metabolism, correlating with IL-6 levels and renal status.
Thomas T, Stefanoni D, Reisz JA, Nemkov T, Bertolone L, Francis RO, Hudson KE, Zimring JC, Hansen KC, Hod EA, Spitalnik SL, D'Alessandro A. Thomas T, et al. Among authors: d alessandro a. JCI Insight. 2020 Jul 23;5(14):e140327. doi: 10.1172/jci.insight.140327. JCI Insight. 2020. PMID: 32559180 Free PMC article.
BACKGROUNDReprogramming of host metabolism supports viral pathogenesis by fueling viral proliferation, by providing, for example, free amino acids and fatty acids as building blocks.METHODSTo investigate metabolic effects of SARS-CoV-2 infection, we evaluated …
BACKGROUNDReprogramming of host metabolism supports viral pathogenesis by fueling viral proliferation, by providing, for example, free amino …
SARS-CoV-2 Infection and Anemia-A Focus on RBC Deformability and Membrane Proteomics-Integrated Observational Prospective Study.
D'Alessandro A, Krisnevskaya E, Leguizamon V, Hernández I, de la Torre C, Bech JJ, Navarro JT, Vives-Corrons JL. D'Alessandro A, et al. Microorganisms. 2024 Feb 23;12(3):453. doi: 10.3390/microorganisms12030453. Microorganisms. 2024. PMID: 38543504 Free PMC article.
This study elucidates the potential association between SARS-CoV-2 infection and anemia, with a particular emphasis on the deformability of red blood cells (RBCs), stability of hemoglobin, enzymatic activities, and proteomic profiles. ...CONCLUSIONS: This res …
This study elucidates the potential association between SARS-CoV-2 infection and anemia, with a particular emphasis on …
Omics markers of platelet transfusion in trauma patients.
LaCroix IS, Cohen M, Moore EE, Dzieciatkowska M, Silliman CC, Hansen KC, D'Alessandro A. LaCroix IS, et al. Among authors: d alessandro a. Transfusion. 2023 Aug;63(8):1447-1462. doi: 10.1111/trf.17472. Epub 2023 Jul 19. Transfusion. 2023. PMID: 37466356
BACKGROUND: Even in the era of the COVID-19 pandemic, trauma remains the global leading cause of mortality under the age of 49. ...
BACKGROUND: Even in the era of the COVID-19 pandemic, trauma remains the global leading cause of mortality under the age of 49 …
Interferon-inducible phospholipids govern IFITM3-dependent endosomal antiviral immunity.
Unali G, Crivicich G, Pagani I, Abou-Alezz M, Folchini F, Valeri E, Matafora V, Reisz JA, Giordano AMS, Cuccovillo I, Butta GM, Donnici L, D'Alessandro A, De Francesco R, Manganaro L, Cittaro D, Merelli I, Petrillo C, Bachi A, Vicenzi E, Kajaste-Rudnitski A. Unali G, et al. Among authors: d alessandro a. EMBO J. 2023 May 15;42(10):e112234. doi: 10.15252/embj.2022112234. Epub 2023 Mar 27. EMBO J. 2023. PMID: 36970857 Free PMC article.
Unlike plasma membrane (PM)-localized IFITM restriction that targets infectious SARS-CoV2 and other PM-fusing viral envelopes, inhibition of endosomal viral entry depends on lysines within the conserved IFITM intracellular loop. ...PIP3 levels correlated with the po …
Unlike plasma membrane (PM)-localized IFITM restriction that targets infectious SARS-CoV2 and other PM-fusing viral envelopes, …
Biological and Clinical Factors Contributing to the Metabolic Heterogeneity of Hospitalized Patients with and without COVID-19.
D'Alessandro A, Thomas T, Akpan IJ, Reisz JA, Cendali FI, Gamboni F, Nemkov T, Thangaraju K, Katneni U, Tanaka K, Kahn S, Wei AZ, Valk JE, Hudson KE, Roh D, Moriconi C, Zimring JC, Hod EA, Spitalnik SL, Buehler PW, Francis RO. D'Alessandro A, et al. Cells. 2021 Sep 2;10(9):2293. doi: 10.3390/cells10092293. Cells. 2021. PMID: 34571942 Free PMC article.
The Corona Virus Disease 2019 (COVID-19) pandemic represents an ongoing worldwide challenge. The present large study sought to understand independent and overlapping metabolic features of samples from acutely ill patients (n = 831) that tested positive (n = 543) or …
The Corona Virus Disease 2019 (COVID-19) pandemic represents an ongoing worldwide challenge. The present large study sought to …
22 results