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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1986 2
1987 11
1988 14
1989 25
1990 30
1991 56
1992 76
1993 106
1994 141
1995 138
1996 124
1997 108
1998 113
1999 95
2000 107
2001 129
2002 146
2003 123
2004 170
2005 182
2006 191
2007 153
2008 178
2009 220
2010 203
2011 250
2012 277
2013 235
2014 251
2015 200
2016 187
2017 183
2018 160
2019 79
2020 0
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4,265 results
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Page 1
Rules of engagement between αvβ6 integrin and foot-and-mouth disease virus
Kotecha A, et al. Nat Commun 2017. PMID 28534487 Free PMC article.
Foot-and-mouth disease virus (FMDV) mediates cell entry by attachment to an integrin receptor, generally αvβ6, via a conserved arginine-glycine-aspartic acid (RGD) motif in the exposed, antigenic, GH loop of capsid protein VP1. ...
Foot-and-mouth disease virus (FMDV) mediates cell entry by attachment to an integrin receptor, generally αvβ6, via a conserved arginine-glyc …
Emergence of Small-Molecule Non-RGD-Mimetic Inhibitors for RGD Integrins
Miller LM, et al. J Med Chem 2017 - Review. PMID 28135089 Free article.
Current inhibitors are designed to mimic the tripeptide sequence (arginine-glycine-aspartic acid) of the natural ligands; however, the RGD-mimetic antagonists for α(IIb)β(3) have been shown to cause partial agonism, leading to the opposite pharmacological effect. ...
Current inhibitors are designed to mimic the tripeptide sequence (arginine-glycine-aspartic acid) of the natural ligands; howe …
Efficient siRNA transfer to knockdown a placenta specific lncRNA using RGD-modified nano-liposome: A new preeclampsia-like mouse model
Yu Q, et al. Int J Pharm 2018. PMID 29729405
Because of the high expression level of integrin αvβ3 on the placenta, arginine-glycine-aspartic acid peptide (RGD) modified PEGylated cationic liposome (RGD-Lip) was designed as a novel gene delivery system to target the placenta safely and efficiently, and a new animal model of preeclampsia was established through targeting of long noncoding RNA (lncRNA). ...
Because of the high expression level of integrin αvβ3 on the placenta, arginine-glycine-aspartic acid peptide (RGD) modified P …
3D culture of human pluripotent stem cells in RGD-alginate hydrogel improves retinal tissue development
Hunt NC, et al. Acta Biomater 2017. PMID 27826002 Free article.
It was hypothesised that generation of laminated neural retina and/or RPE from hiPSCs/hESCs could be enhanced by three dimensional (3D) culture in hydrogels. hiPSC- and hESC-derived embryoid bodies (EBs) were encapsulated in 0.5% RGD-alginate; 1% RGD-alginate; hyaluronic acid (HA) or HA/gelatin hydrogels and maintained until day 45. ...This study indicated that alginate hydrogels enhanced retinal tissue development from PSCs, whereas hyaluronic acid-based hydrogels did not. ...
It was hypothesised that generation of laminated neural retina and/or RPE from hiPSCs/hESCs could be enhanced by three dimensional (3D) cult …
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