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1,686 results

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Page 1
Phage Therapy for Antibiotic-Resistant Bacterial Infections.
Hatfull GF, Dedrick RM, Schooley RT. Hatfull GF, et al. Annu Rev Med. 2022 Jan 27;73:197-211. doi: 10.1146/annurev-med-080219-122208. Epub 2021 Aug 24. Annu Rev Med. 2022. PMID: 34428079 Review.
The therapeutic use of bacteriophages has long been considered, with numerous anecdotal reports of success. Interest in phage therapy has been renewed by recent clinical successes in case studies with personalized phage cocktails, and several clinical trials …
The therapeutic use of bacteriophages has long been considered, with numerous anecdotal reports of success. Interest in phage ther
Phage therapy for respiratory infections.
Chang RYK, Wallin M, Lin Y, Leung SSY, Wang H, Morales S, Chan HK. Chang RYK, et al. Adv Drug Deliv Rev. 2018 Aug;133:76-86. doi: 10.1016/j.addr.2018.08.001. Epub 2018 Aug 7. Adv Drug Deliv Rev. 2018. PMID: 30096336 Free PMC article. Review.
We have reviewed and presented on the prospects of inhaled phage therapy as a complementary treatment option with current antibiotics and as a preventative means. Inhaled phage therapy has the potential to transform the prevention and treatment of bact …
We have reviewed and presented on the prospects of inhaled phage therapy as a complementary treatment option with current anti …
Bacteriophage Therapy: Clinical Trials and Regulatory Hurdles.
Furfaro LL, Payne MS, Chang BJ. Furfaro LL, et al. Front Cell Infect Microbiol. 2018 Oct 23;8:376. doi: 10.3389/fcimb.2018.00376. eCollection 2018. Front Cell Infect Microbiol. 2018. PMID: 30406049 Free PMC article. Review.
Phage therapy is rapidly evolving and has resulted in cases of life-saving therapeutic use and multiple clinical trials. ...This review discusses the multi-drug resistant Gram-negative pathogens of highest critical priority and summarizes the current state-of-the-ar
Phage therapy is rapidly evolving and has resulted in cases of life-saving therapeutic use and multiple clinical trials. ...Th
Bacteriophages and its applications: an overview.
Sharma S, Chatterjee S, Datta S, Prasad R, Dubey D, Prasad RK, Vairale MG. Sharma S, et al. Folia Microbiol (Praha). 2017 Jan;62(1):17-55. doi: 10.1007/s12223-016-0471-x. Epub 2016 Oct 8. Folia Microbiol (Praha). 2017. PMID: 27718043 Review.
However, due to recent emergence of bacterial resistance on antibiotics, applications of phage (phage therapy) become an inevitable option of research. Phage particles become popular as a biotechnological tool and treatment of pathogenic bacteria in a …
However, due to recent emergence of bacterial resistance on antibiotics, applications of phage (phage therapy) become a …
Phage therapy: From biological mechanisms to future directions.
Strathdee SA, Hatfull GF, Mutalik VK, Schooley RT. Strathdee SA, et al. Cell. 2023 Jan 5;186(1):17-31. doi: 10.1016/j.cell.2022.11.017. Cell. 2023. PMID: 36608652 Free article. Review.
Increasing antimicrobial resistance rates have revitalized bacteriophage (phage) research, the natural predators of bacteria discovered over 100 years ago. ...Developing therapeutic phages takes a coordinated effort of multiple stakeholders. Herein, we review the state of …
Increasing antimicrobial resistance rates have revitalized bacteriophage (phage) research, the natural predators of bacteria discover …
Biotechnological applications of bacteriophages: State of the art.
Harada LK, Silva EC, Campos WF, Del Fiol FS, Vila M, Dąbrowska K, Krylov VN, Balcão VM. Harada LK, et al. Microbiol Res. 2018 Jul-Aug;212-213:38-58. doi: 10.1016/j.micres.2018.04.007. Epub 2018 Apr 30. Microbiol Res. 2018. PMID: 29853167 Free article. Review.
The study of bacteriophage particles potentially sheds light on the development of new biotechnology products. Bacteriophage therapy, although not new, makes use of strictly lytic phage particles as an alternative in the antimicrobial treatment of resistant bacteria …
The study of bacteriophage particles potentially sheds light on the development of new biotechnology products. Bacteriophage therapy, …
Phage Therapy: Going Temperate?
Monteiro R, Pires DP, Costa AR, Azeredo J. Monteiro R, et al. Trends Microbiol. 2019 Apr;27(4):368-378. doi: 10.1016/j.tim.2018.10.008. Epub 2018 Nov 19. Trends Microbiol. 2019. PMID: 30466900 Review.
Strictly lytic phages have been consensually preferred for phage therapy purposes. In contrast, temperate phages have been avoided due to an inherent capacity to mediate transfer of genes between bacteria by specialized transduction - an event that may increase bact …
Strictly lytic phages have been consensually preferred for phage therapy purposes. In contrast, temperate phages have been avo …
Bacteria-phage interactions in natural environments.
Díaz-Muñoz SL, Koskella B. Díaz-Muñoz SL, et al. Adv Appl Microbiol. 2014;89:135-83. doi: 10.1016/B978-0-12-800259-9.00004-4. Adv Appl Microbiol. 2014. PMID: 25131402 Review.
In this review, we examine bacteria and phage distributions in nature first by highlighting biogeographic patterns and nonhost environmental influences on phage distribution, then by considering the ways in which phages and bacteria interact, emphasizing phage
In this review, we examine bacteria and phage distributions in nature first by highlighting biogeographic patterns and nonhost enviro …
Formulation, stabilisation and encapsulation of bacteriophage for phage therapy.
Malik DJ, Sokolov IJ, Vinner GK, Mancuso F, Cinquerrui S, Vladisavljevic GT, Clokie MRJ, Garton NJ, Stapley AGF, Kirpichnikova A. Malik DJ, et al. Adv Colloid Interface Sci. 2017 Nov;249:100-133. doi: 10.1016/j.cis.2017.05.014. Epub 2017 May 14. Adv Colloid Interface Sci. 2017. PMID: 28688779 Free article. Review.
In addition, in vitro and animal studies have shown the importance of using phage cocktails rather than single phage preparations to achieve better therapy outcomes. ...Modelling of phage-bacterium population dynamics reinforces these points. Surprisin …
In addition, in vitro and animal studies have shown the importance of using phage cocktails rather than single phage preparati …
Phage-Based Applications in Synthetic Biology.
Lemire S, Yehl KM, Lu TK. Lemire S, et al. Annu Rev Virol. 2018 Sep 29;5(1):453-476. doi: 10.1146/annurev-virology-092917-043544. Epub 2018 Jul 12. Annu Rev Virol. 2018. PMID: 30001182 Free PMC article. Review.
Bacteriophage research has been instrumental to advancing many fields of biology, such as genetics, molecular biology, and synthetic biology. Many phage-derived technologies have been adapted for building gene circuits to program biological systems. ...Furthermore, phages …
Bacteriophage research has been instrumental to advancing many fields of biology, such as genetics, molecular biology, and synthetic biology …
1,686 results