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550 results

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Quoted phrase not found in phrase index: "steoroids"
Page 1
Recent advances in drug delivery systems for targeting cancer stem cells.
Duan H, Liu Y, Gao Z, Huang W. Duan H, et al. Acta Pharm Sin B. 2021 Jan;11(1):55-70. doi: 10.1016/j.apsb.2020.09.016. Epub 2020 Oct 2. Acta Pharm Sin B. 2021. PMID: 33532180 Free PMC article. Review.
Cancer stem cells (CSCs) are a subpopulation of cancer cells with functions similar to those of normal stem cells. ...Thus, they play an important role in the occurrence and development of tumors, and they are closely related to tumor invasion, metastasis, dr
Cancer stem cells (CSCs) are a subpopulation of cancer cells with functions similar to those of normal stem cells. ...Thus, th
Benzaldehyde suppresses epithelial-mesenchymal plasticity and overcomes treatment resistance in cancer by targeting the interaction of 14-3-3zeta with H3S28ph.
Saito J, Onishi N, Yamasaki J, Koike N, Hata Y, Kimura K, Otsuki Y, Nobusue H, Sampetrean O, Shimizu T, Okazaki S, Sugihara E, Saya H. Saito J, et al. Br J Cancer. 2025 Jul;133(1):27-39. doi: 10.1038/s41416-025-03006-4. Epub 2025 May 2. Br J Cancer. 2025. PMID: 40316727 Free PMC article.
METHODS: We investigated the cytotoxic effects of BA on cancer cells, and probed its effects on intracellular signaling pathways. The anticancer effects of BA in vivo were studied by using a mouse orthotopic transplantation model of pancreatic cancer. ...Treatment o …
METHODS: We investigated the cytotoxic effects of BA on cancer cells, and probed its effects on intracellular signaling pathways. The …
Benzene formation in electronic cigarettes.
Pankow JF, Kim K, McWhirter KJ, Luo W, Escobedo JO, Strongin RM, Duell AK, Peyton DH. Pankow JF, et al. PLoS One. 2017 Mar 8;12(3):e0173055. doi: 10.1371/journal.pone.0173055. eCollection 2017. PLoS One. 2017. PMID: 28273096 Free PMC article.
In the two tank systems benzene was found to form from propylene glycol (PG) and glycerol (GL), and from the additives benzoic acid and benzaldehyde, especially at high power settings. With 50:50 PG+GL, for tank device 1 at 6W and 13W, the formed benzene concentrations wer …
In the two tank systems benzene was found to form from propylene glycol (PG) and glycerol (GL), and from the additives benzoic acid and b
RIFM fragrance ingredient safety assessment, p-tolualdehyde, CAS Registry Number 104-87-0.
Api AM, Belsito D, Biserta S, Botelho D, Bruze M, Burton GA Jr, Buschmann J, Cancellieri MA, Dagli ML, Date M, Dekant W, Deodhar C, Fryer AD, Gadhia S, Jones L, Joshi K, Lapczynski A, Lavelle M, Liebler DC, Na M, O'Brien D, Patel A, Penning TM, Ritacco G, Rodriguez-Ropero F, Romine J, Sadekar N, Salvito D, Schultz TW, Siddiqi F, Sipes IG, Sullivan G, Thakkar Y, Tokura Y, Tsang S. Api AM, et al. Food Chem Toxicol. 2021 Mar;149 Suppl 1:111982. doi: 10.1016/j.fct.2021.111982. Epub 2021 Jan 14. Food Chem Toxicol. 2021. PMID: 33454360 Review.
The existing information supports the use of this material as described in this safety assessment. p-Tolualdehyde was evaluated for genotoxicity, repeated dose toxicity, developmental and reproductive toxicity, local respiratory toxicity, phototoxicity, skin sensitization …
The existing information supports the use of this material as described in this safety assessment. p-Tolualdehyde was evaluated for genotoxi …
Discovery, chemistry, and reproductive pharmacology of asoprisnil and related 11beta-benzaldoxime substituted selective progesterone receptor modulators (SPRMs).
Schubert G, Elger W, Kaufmann G, Schneider B, Reddersen G, Chwalisz K. Schubert G, et al. Semin Reprod Med. 2005 Feb;23(1):58-73. doi: 10.1055/s-2005-864034. Semin Reprod Med. 2005. PMID: 15714390 Review.
Asoprisnil (J 867; benzaldehyde, 4-[(11beta, 17beta)-17-methoxy-17-(methoxymethyl)-3-oxoestra-4, 9-dien-11beta-yl]-, 1-oxime) is the prototype of a novel class 11beta-benzaldoxime-substituted selective progesterone receptor modulators (SPRMs) and the first-in-class …
Asoprisnil (J 867; benzaldehyde, 4-[(11beta, 17beta)-17-methoxy-17-(methoxymethyl)-3-oxoestra-4, 9-dien-11beta-yl]-, 1-oxime) is the …
Fecal Microbiota, Fecal Metabolome, and Colorectal Cancer Interrelations.
Sinha R, Ahn J, Sampson JN, Shi J, Yu G, Xiong X, Hayes RB, Goedert JJ. Sinha R, et al. PLoS One. 2016 Mar 25;11(3):e0152126. doi: 10.1371/journal.pone.0152126. eCollection 2016. PLoS One. 2016. PMID: 27015276 Free PMC article.
BACKGROUND AND AIMS: Investigation of microbe-metabolite relationships in the gut is needed to understand and potentially reduce colorectal cancer (CRC) risk. METHODS: Microbiota and metabolomics profiling were performed on lyophilized feces from 42 CRC cases and 89 matche …
BACKGROUND AND AIMS: Investigation of microbe-metabolite relationships in the gut is needed to understand and potentially reduce colorectal …
Targeting DNA-Dependent Protein Kinase for Cancer Therapy.
Harnor SJ, Brennan A, Cano C. Harnor SJ, et al. ChemMedChem. 2017 Jun 21;12(12):895-900. doi: 10.1002/cmdc.201700143. Epub 2017 May 29. ChemMedChem. 2017. PMID: 28423228 Review.
This includes repair of DSB lesions resulting from oxidative stress, oncogene-induced transcription, or following therapeutic treatment of cancer cells. Armed with this knowledge, many attempts have been made to identify small-molecule inhibitors of DNA-PK activity as an a …
This includes repair of DSB lesions resulting from oxidative stress, oncogene-induced transcription, or following therapeutic treatment of …
Anti-cancer activity of heteroaromatic acetals of andrographolide and its isomers.
Tamang N, Andrews C, Mavileti SK, Nanduri S, Golakoti NR, Karanam B. Tamang N, et al. New J Chem. 2022 May 24;46(20):9745-9754. doi: 10.1039/D2NJ01055K. Epub 2022 Apr 22. New J Chem. 2022. PMID: 36093125 Free PMC article.
Preliminary studies suggested that acetals synthesized using benzaldehyde improved anticancer activity. Compound 2a showed the highest growth inhibition of 90.97% against the leukaemia cancer cell line CCRF-CEM. Andrographolide and seven selected compounds were test …
Preliminary studies suggested that acetals synthesized using benzaldehyde improved anticancer activity. Compound 2a showed the highes …
Amygdalin - A pharmacological and toxicological review.
He XY, Wu LJ, Wang WX, Xie PJ, Chen YH, Wang F. He XY, et al. J Ethnopharmacol. 2020 May 23;254:112717. doi: 10.1016/j.jep.2020.112717. Epub 2020 Feb 27. J Ethnopharmacol. 2020. PMID: 32114166
Analysis on the data suggested that this compound presented pharmacological activities of anti-tumor, anti-fibrotic, anti-inflammatory, analgesic, immunomodulatory, anti-atherosclerosis, ameliorating digestive system and reproductive system, improving neurodegenerat …
Analysis on the data suggested that this compound presented pharmacological activities of anti-tumor, anti-fibrotic, anti-inflammator …
Protocols to Study Behavior in Drosophila.
Neckameyer WS, Bhatt P. Neckameyer WS, et al. Methods Mol Biol. 2016;1478:303-320. doi: 10.1007/978-1-4939-6371-3_19. Methods Mol Biol. 2016. PMID: 27730591 Review.
Importantly, this also allows for one to control for reproductive status, age, and sex, since these factors all have a significant impact on adult behaviors. ...
Importantly, this also allows for one to control for reproductive status, age, and sex, since these factors all have a significant im …
550 results