Paraben preservatives exhibit inhibition on human and rat steroid 5α-reductase 1: A comprehensive 3D-QSAR and computational analysis.
Zhu H, Ding C, Tang Y, Zheng J, Wang S, Ji Z, Zhu Y, Ge RS, Li H.
Zhu H, et al.
J Hazard Mater. 2024 Dec 5;480:135841. doi: 10.1016/j.jhazmat.2024.135841. Epub 2024 Sep 19.
J Hazard Mater. 2024.
PMID: 39326151
The results showed that methyl, ethyl, propyl, butyl, hexyl, heptyl, nonyl, phenyl, and benzyl paraben inhibited human SRD5A1, with nonylparaben having the strongest effect (7.59 muM). ...
The results showed that methyl, ethyl, propyl, butyl, hexyl, heptyl, nonyl, phenyl, and benzyl paraben inhibited human SRD5A1, …