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Quoted phrase not found in phrase index: "steoroids"
Page 1
Three-step biosynthesis of salicylic acid from benzoyl-CoA in plants.
Liu Y, Xu L, Wu M, Wang J, Qiu D, Lan J, Lu J, Zhang Y, Li X, Zhang Y. Liu Y, et al. Nature. 2025 Sep;645(8079):201-207. doi: 10.1038/s41586-025-09185-7. Epub 2025 Jul 23. Nature. 2025. PMID: 40702178
Aspirin, a derivative of SA, is the most widely used medication in human history. SA also acts as a key plant defence hormone(1-4). Although SA was known to be produced from chorismate in the model plant Arabidopsis(5,6), how it is biosynthesized in plant families outside …
Aspirin, a derivative of SA, is the most widely used medication in human history. SA also acts as a key plant defence hormone(1-4). A …
A critical assessment of the estrogenic potency of benzyl salicylate.
Natsch A, Hostettler L, Haupt T, Laue H. Natsch A, et al. Toxicol Rep. 2021 May 4;8:1002-1007. doi: 10.1016/j.toxrep.2021.05.001. eCollection 2021. Toxicol Rep. 2021. PMID: 34408969 Free PMC article.
Benzyl salicylate (BS) is a natural ingredient of essential oils and a widely used fragrance chemical. A number of in vitro screening studies have evaluated the estrogenic potential of BS with ambiguous results. Lack of dose-response information for the posit …
Benzyl salicylate (BS) is a natural ingredient of essential oils and a widely used fragrance chemical. A number of in vitro sc …
The estrogenic potential of salicylate esters and their possible risks in foods and cosmetics.
Zhang Z, Jia C, Hu Y, Sun L, Jiao J, Zhao L, Zhu D, Li J, Tian Y, Bai H, Li R, Hu J. Zhang Z, et al. Toxicol Lett. 2012 Mar 7;209(2):146-53. doi: 10.1016/j.toxlet.2011.12.004. Epub 2011 Dec 16. Toxicol Lett. 2012. PMID: 22197706
Salicylate esters (SEs), a class of chemicals extensively used as flavor and fragrance additives in foods, beverages and a wide variety of consumer products, are suspected to have estrogenic activity based on chemical analysis of in silica molecular docking. We evaluated t …
Salicylate esters (SEs), a class of chemicals extensively used as flavor and fragrance additives in foods, beverages and a wide variety of c …
Evaluation of Placental Toxicity of Five Essential Oils and Their Potential Endocrine-Disrupting Effects.
Fouyet S, Olivier E, Leproux P, Dutot M, Rat P. Fouyet S, et al. Curr Issues Mol Biol. 2022 Jun 28;44(7):2794-2810. doi: 10.3390/cimb44070192. Curr Issues Mol Biol. 2022. PMID: 35877416 Free PMC article.
Little is known about the potential danger that EOs represent for the placenta and therefore for the pregnancy. Our aim was to explore and compare the placental toxicity and potential endocrine disrupting effects of niaouli, orange, tea tree, wintergreen and ylang-y …
Little is known about the potential danger that EOs represent for the placenta and therefore for the pregnancy. Our aim was to explor …
Oestrogenic activity of benzyl salicylate, benzyl benzoate and butylphenylmethylpropional (Lilial) in MCF7 human breast cancer cells in vitro.
Charles AK, Darbre PD. Charles AK, et al. J Appl Toxicol. 2009 Jul;29(5):422-34. doi: 10.1002/jat.1429. J Appl Toxicol. 2009. PMID: 19338011
Benzyl salicylate, benzyl benzoate and butylphenylmethylpropional (Lilial) are added to bodycare cosmetics used around the human breast. ...This demonstrates that benzyl salicylate, benzyl benzoate and butylphenylmethylpropional are furth …
Benzyl salicylate, benzyl benzoate and butylphenylmethylpropional (Lilial) are added to bodycare cosmetics used around …
Estrogenic activity of tissue conditioners in vitro.
Hashimoto Y, Kawaguchi M, Miyazaki K, Nakamura M. Hashimoto Y, et al. Dent Mater. 2003 Jun;19(4):341-6. doi: 10.1016/s0109-5641(02)00064-7. Dent Mater. 2003. PMID: 12686300
Four commercial tissue conditioners were also diluted to concentrations ranging from 2 x 10(-8) to 2 x 10(-3)g/ml. Estrogenic activities were tested by the E-screen test using MCF-7 cells. When estrogen is present, the cells proliferate. ...SIGNIFICANCE: Except for …
Four commercial tissue conditioners were also diluted to concentrations ranging from 2 x 10(-8) to 2 x 10(-3)g/ml. Estrogenic activit …
Unraveling the environmental links to feline hyperthyroidism: Insights from silicone passive samplers.
Nelson IM, Vazquez JH, Poutasse CM, Adams KT, O'Connell SG, Smith BW, Herbstman JB, Raessler JM, Anderson KA. Nelson IM, et al. Environ Res. 2025 Dec 1;286(Pt 2):122885. doi: 10.1016/j.envres.2025.122885. Epub 2025 Sep 17. Environ Res. 2025. PMID: 40972849 Free PMC article.
This disease is caused by the effects of excess thyroid hormone production and causes a variety of symptoms including weight loss, increased urination, and increased appetite. ...Many consumer products also contain other endocrine-disrupting chemicals (EDC …
This disease is caused by the effects of excess thyroid hormone production and causes a variety of symptoms including weight l …
Initial hazard assessment of benzyl salicylate: In vitro genotoxicity test and combined repeated-dose and reproductive/developmental toxicity screening test in rats.
Igarashi T, Takashima H, Takabe M, Suzuki H, Ushida K, Kawamura T, Matsumoto M, Iso T, Tanabe S, Inoue K, Ono A, Yamada T, Hirose A. Igarashi T, et al. Regul Toxicol Pharmacol. 2018 Dec;100:105-117. doi: 10.1016/j.yrtph.2018.10.018. Epub 2018 Oct 22. Regul Toxicol Pharmacol. 2018. PMID: 30359701
Benzyl salicylate is used as a fragrance ingredient and an ultraviolet light absorber, but its toxicity is unknown. ...Furthermore, although benzyl salicylate had no effect on the estrus cycle, fertility, corpus lutea, or implantation rate, embr …
Benzyl salicylate is used as a fragrance ingredient and an ultraviolet light absorber, but its toxicity is unknown. ...Further …
Simultaneous determination of the UV-filters benzyl salicylate, phenyl salicylate, octyl salicylate, homosalate, 3-(4-methylbenzylidene) camphor and 3-benzylidene camphor in human placental tissue by LC-MS/MS. Assessment of their in vitro endocrine activity.
Jiménez-Díaz I, Molina-Molina JM, Zafra-Gómez A, Ballesteros O, Navalón A, Real M, Sáenz JM, Fernández MF, Olea N. Jiménez-Díaz I, et al. J Chromatogr B Analyt Technol Biomed Life Sci. 2013 Oct 1;936:80-7. doi: 10.1016/j.jchromb.2013.08.006. Epub 2013 Aug 8. J Chromatogr B Analyt Technol Biomed Life Sci. 2013. PMID: 24004914
All tested compounds, except benzyl salicylate and octyl salicylate, showed estrogenic activity in the E-Screen bioassay whereas only homosalate and 3-(4-methylbenzylidene) camphor were potent hAR antagonists. Although free salicylate derivatives and free cam …
All tested compounds, except benzyl salicylate and octyl salicylate, showed estrogenic activity in the E-Screen bioassa …
Next generation risk assessment: an ab initio case study to assess the systemic safety of the cosmetic ingredient, benzyl salicylate, after dermal exposure.
Ebmeyer J, Najjar A, Lange D, Boettcher M, Voß S, Brandmair K, Meinhardt J, Kuehnl J, Hewitt NJ, Krueger CT, Schepky A. Ebmeyer J, et al. Front Pharmacol. 2024 Mar 7;15:1345992. doi: 10.3389/fphar.2024.1345992. eCollection 2024. Front Pharmacol. 2024. PMID: 38515841 Free PMC article.
We performed an ab initio next-generation risk assessment (NGRA) for a fragrance ingredient, benzyl salicylate (BSal), to demonstrate how cosmetic ingredients can be evaluated for systemic toxicity endpoints based on non-animal approaches. New approach methodologies …
We performed an ab initio next-generation risk assessment (NGRA) for a fragrance ingredient, benzyl salicylate (BSal), to demo …
16 results