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Quoted phrases not found in phrase index: "benzylcarbamide", "N-benzylurea"
Page 1
Phenyl- and benzylurea cytokinins as competitive inhibitors of cytokinin oxidase/dehydrogenase: a structural study.
Kopecný D, Briozzo P, Popelková H, Sebela M, Koncitíková R, Spíchal L, Nisler J, Madzak C, Frébort I, Laloue M, Houba-Hérin N. Kopecný D, et al. Biochimie. 2010 Aug;92(8):1052-62. doi: 10.1016/j.biochi.2010.05.006. Epub 2010 May 15. Biochimie. 2010. PMID: 20478354
The crystal structures of L492A mutant in a complex with CPPU and N-(2-chloro-pyridin-4-yl)-N'-benzylurea (CPBU) were solved and confirm the importance of a stacking interaction between the 2-chloro-4-pyridinyl ring of the inhibitor and the isoalloxazine ring of the FAD co …
The crystal structures of L492A mutant in a complex with CPPU and N-(2-chloro-pyridin-4-yl)-N'-benzylurea (CPBU) were solved and conf …
Benzylamides from Salvadora persica.
Khalil AT. Khalil AT. Arch Pharm Res. 2006 Nov;29(11):952-6. doi: 10.1007/BF02969277. Arch Pharm Res. 2006. PMID: 17146962
The isolated compounds were identified as butanediamide, N1,N4-bis(phenylmethyl)-2(S)-hydroxy-butanediamide (1), N-benzyl-2-phenylacetamide (2), N-benzylbenzamide (3) and benzylurea (4). The structure elucidation was accomplished using spectroscopic methods, especially 2D …
The isolated compounds were identified as butanediamide, N1,N4-bis(phenylmethyl)-2(S)-hydroxy-butanediamide (1), N-benzyl-2-phenylacetamide …
Benzylurea Protects hPDLFs Against LPS-Induced Mitochondrial Dysfunction Through MTCH2.
Liu L, Bai J, Wang J, Fan J, Yin D, Chang H, Hui X, Yang P. Liu L, et al. Oral Dis. 2024 Nov 3. doi: 10.1111/odi.15172. Online ahead of print. Oral Dis. 2024. PMID: 39491029
OBJECTIVE: The aim of this study is to explore the mechanism of benzylurea in the inflammatory injury of human periodontal ligament fibroblasts (hPDLFs). ...CONCLUSION: CYB5B may act as an effector of MTCH2, with benzylurea enhancing mitochondrial function and prote …
OBJECTIVE: The aim of this study is to explore the mechanism of benzylurea in the inflammatory injury of human periodontal ligament f …
Synthesis and Structure-Activity relationship of 1-(5-isoquinolinesulfonyl)piperazine analogues as inhibitors of Mycobacterium tuberculosis IMPDH.
Singh V, Pacitto A, Donini S, Ferraris DM, Boros S, Illyés E, Szokol B, Rizzi M, Blundell TL, Ascher DB, Pato J, Mizrahi V. Singh V, et al. Eur J Med Chem. 2019 Jul 15;174:309-329. doi: 10.1016/j.ejmech.2019.04.027. Epub 2019 Apr 15. Eur J Med Chem. 2019. PMID: 31055147 Free PMC article.
We also show that the nitrogen in urea analogues is required for anti-tubercular activity and identify benzylurea derivatives as promising inhibitors that warrant further investigation....
We also show that the nitrogen in urea analogues is required for anti-tubercular activity and identify benzylurea derivatives as prom …
Unraveling the metabolome composition and its implication for Salvadora persica L. use as dental brush via a multiplex approach of NMR and LC-MS metabolomics.
Farag MA, Shakour ZT, Lübken T, Frolov A, Wessjohann LA, Mahrous E. Farag MA, et al. J Pharm Biomed Anal. 2021 Jan 30;193:113727. doi: 10.1016/j.jpba.2020.113727. Epub 2020 Nov 2. J Pharm Biomed Anal. 2021. PMID: 33197832
LC/MS metabolomics identified flavonoids (8), benzylurea derivatives (5), butanediamides (3), phenolic acids (8) and 5 sulfur compounds, with 21 constituents reported for the first time in S. persica. ...
LC/MS metabolomics identified flavonoids (8), benzylurea derivatives (5), butanediamides (3), phenolic acids (8) and 5 sulfur compoun …
Discovery of Biased Mu-Opioid Receptor Agonists for the Treatment of Pain.
Ma M, Li X, Tong K, Cheng J, Yu Z, Ren F, Zhong B, Shi W. Ma M, et al. ChemMedChem. 2020 Jan 7;15(1):155-161. doi: 10.1002/cmdc.201900575. Epub 2019 Nov 26. ChemMedChem. 2020. PMID: 31729174
Compounds 7 i ((S)-1-(3-(benzo[d][1,3]dioxol-4-yl)-2-(dimethylamino)propyl)-3-phenethylurea) and 7 j ((S)-1-(3-(benzo[d][1,3]dioxol-4-yl)-2-(dimethylamino)propyl)-3-benzylurea) could serve as new leads for further modifications to find novel biased MOR agonists with greate …
Compounds 7 i ((S)-1-(3-(benzo[d][1,3]dioxol-4-yl)-2-(dimethylamino)propyl)-3-phenethylurea) and 7 j ((S)-1-(3-(benzo[d][1,3]dioxol-4-yl)-2- …
Synthesis of unsymmetrical diarylureas via Pd-catalyzed C-N cross-coupling reactions.
Breitler S, Oldenhuis NJ, Fors BP, Buchwald SL. Breitler S, et al. Org Lett. 2011 Jun 17;13(12):3262-5. doi: 10.1021/ol201210t. Epub 2011 May 23. Org Lett. 2011. PMID: 21604792 Free PMC article.
The utilization of the Pd-catalyzed arylation of ureas enables the synthesis of an array of diarylureas in good to excellent yields from benzylurea via a one-pot arylation-deprotection protocol, followed by a second arylation....
The utilization of the Pd-catalyzed arylation of ureas enables the synthesis of an array of diarylureas in good to excellent yields from …
New benzylureas as a novel series of potent, nonpeptidic vasopressin V2 receptor agonists.
Yea CM, Allan CE, Ashworth DM, Barnett J, Baxter AJ, Broadbridge JD, Franklin RJ, Hampton SL, Hudson P, Horton JA, Jenkins PD, Penson AM, Pitt GR, Rivière P, Robson PA, Rooker DP, Semple G, Sheppard A, Haigh RM, Roe MB. Yea CM, et al. J Med Chem. 2008 Dec 25;51(24):8124-34. doi: 10.1021/jm8008162. J Med Chem. 2008. PMID: 19053774
We report herein the discovery of potent, nonpeptidic, benzylurea derived agonists of the vasopressin V2 receptor. We describe substitutions on the benzyl group to give improvements in potency and subsequent modifications to the urea end group to provide improvements in so …
We report herein the discovery of potent, nonpeptidic, benzylurea derived agonists of the vasopressin V2 receptor. We describe substi …
Effects of Ligands in Rare Earth Complex on Properties, Functions, and Intelligent Behaviors of Polyurea-Urethane Composites.
Zhou L, Yang H, Zhang Z, Liu Y, Epaarachchi J, Fang Z, Fang L, Lu C, Xu Z. Zhou L, et al. Polymers (Basel). 2022 May 21;14(10):2098. doi: 10.3390/polym14102098. Polymers (Basel). 2022. PMID: 35631980 Free PMC article.
REOC I and REOC III (Sm(BUBA)(3)phen: BUBA, 4-benzylurea-benzoic acid) with amine and urea groups facilitate their dispersion. It was REOC III that helped the maintenance of mechanical properties of PUU composites due to the good dispersion and the needle-like morphologies …
REOC I and REOC III (Sm(BUBA)(3)phen: BUBA, 4-benzylurea-benzoic acid) with amine and urea groups facilitate their dispersion. It was …
17 results