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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1975 1
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2000 24
2001 15
2002 14
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2004 25
2005 17
2006 18
2007 19
2008 17
2009 17
2010 14
2011 24
2012 19
2013 15
2014 17
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2016 7
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616 results

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Quoted phrase not found in phrase index: "steoroids"
Page 1
Anticarcinogenesis in fish.
Bailey G, Hendricks J, Dashwood R. Bailey G, et al. Mutat Res. 1992 Jun;267(2):243-50. doi: 10.1016/0027-5107(92)90068-d. Mutat Res. 1992. PMID: 1376426 Review.
For example, beta-naphthoflavone appears to inhibit aflatoxin B1 hepatocarcinogenicity by species-independent mechanisms that readily extrapolate to humans. ...The very low cost of trout tumor studies has enabled statistically challenging issues in molecular …
For example, beta-naphthoflavone appears to inhibit aflatoxin B1 hepatocarcinogenicity by species-independent mechanisms that …
A microfluidic thyroid-liver platform to assess chemical safety in humans.
Kühnlenz J, Karwelat D, Steger-Hartmann T, Raschke M, Bauer S, Vural Ö, Marx U, Tinwell H, Bars R. Kühnlenz J, et al. ALTEX. 2023;40(1):61-82. doi: 10.14573/altex.2108261. Epub 2022 May 9. ALTEX. 2023. PMID: 35536601 Free article.
Thyroid hormones (THs) are crucial regulators of human metabolism and early development. ...To address this complexity, we present human three-dimensional thyroid and liver organoids with key functions of TH metabolism. The thyroid model resembles in vivo-lik …
Thyroid hormones (THs) are crucial regulators of human metabolism and early development. ...To address this complexity, we present hu …
Characterization of beta-Estradiol 3-Glucuronidation in Rat Brain.
Asai Y, Sakakibara Y, Onouchi H, Nadai M, Katoh M. Asai Y, et al. Biol Pharm Bull. 2017;40(9):1556-1560. doi: 10.1248/bpb.b17-00089. Biol Pharm Bull. 2017. PMID: 28867738 Free article.
UGT1A has been found in the brain; therefore, UGT1A may be involved in beta-estradiol 3-glucuronidation in the brain. In the present study, we aimed to characterize the beta-estradiol 3-glucuronidation reaction in the rat brain. beta-Estradiol 3-glucuronidati …
UGT1A has been found in the brain; therefore, UGT1A may be involved in beta-estradiol 3-glucuronidation in the brain. In the present …
Development of organoid-based drug metabolism model.
Park E, Kim HK, Jee J, Hahn S, Jeong S, Yoo J. Park E, et al. Toxicol Appl Pharmacol. 2019 Dec 15;385:114790. doi: 10.1016/j.taap.2019.114790. Epub 2019 Oct 31. Toxicol Appl Pharmacol. 2019. PMID: 31678242
Organoids treated with three CYPs-inducers dexamethasone (Dex), beta-naphthoflavone (BNF), and 1,4-bis-2-(3, 5-dichloropyridyloxy)-benzene (TCPOBOP) were evaluated for CYPs activities. The CYPs-induced intestinal and liver organoids were confirmed to digest more doc …
Organoids treated with three CYPs-inducers dexamethasone (Dex), beta-naphthoflavone (BNF), and 1,4-bis-2-(3, 5-dichloropyridyl …
beta-Naphthoflavone protects from peritonitis by reducing TNF-alpha-induced endothelial cell activation.
Hsu SY, Liou JW, Cheng TL, Peng SY, Lin CC, Chu YY, Luo WC, Huang ZK, Jiang SJ. Hsu SY, et al. Pharmacol Res. 2015 Dec;102:192-9. doi: 10.1016/j.phrs.2015.10.001. Epub 2015 Oct 8. Pharmacol Res. 2015. PMID: 26453957 Free article.
beta-Naphthoflavone (beta-NF), a ligand of the aryl hydrocarbon receptor, has been shown to possess anti-oxidative properties. We investigated the anti-oxidative and anti-inflammatory potential of beta-NF in human microvascular endothelial cells treated with …
beta-Naphthoflavone (beta-NF), a ligand of the aryl hydrocarbon receptor, has been shown to possess anti-oxidative prop …
Hepatic enzyme induction and its potential effect on thyroid hormone metabolism in the metamorphosing tadpole of Xenopus laevis (African clawed frog).
Wada K, Yamaguchi T, Tanaka H, Fujisawa T. Wada K, et al. J Appl Toxicol. 2024 Nov;44(11):1773-1783. doi: 10.1002/jat.4672. Epub 2024 Jul 22. J Appl Toxicol. 2024. PMID: 39039701
Hepatic enzyme induction, an inherent defense system against xenobiotics, is known to simultaneously affect endocrine system functions in mammals under specific conditions, particularly thyroid hormone (TH) regulation. ...Here, we investigated the effects of …
Hepatic enzyme induction, an inherent defense system against xenobiotics, is known to simultaneously affect endocrine system function …
Beta-naphthoflavone inhibits LPS-induced inflammation in BV-2 cells via AKT/Nrf-2/HO-1-NF-kappaB signaling axis.
Gao X, He D, Liu D, Hu G, Zhang Y, Meng T, Su Y, Zhou A, Huang B, Du J, Fu S. Gao X, et al. Immunobiology. 2020 Jul;225(4):151965. doi: 10.1016/j.imbio.2020.151965. Epub 2020 May 28. Immunobiology. 2020. PMID: 32747020
Numerous studies have shown that over-activation of microglia could cause neuroinflammation and release pro-inflammatory mediators, which could result in neurodegenerative diseases, like Parkinson's disease, Alzheimer's disease etc. Beta-naphthoflavone (BNF) has ant …
Numerous studies have shown that over-activation of microglia could cause neuroinflammation and release pro-inflammatory mediators, which co …
beta-Naphthoflavone and Ethanol Reverse Mitochondrial Dysfunction in A Parkinsonian Model of Neurodegeneration.
Fernandez-Abascal J, Chiaino E, Frosini M, Davey GP, Valoti M. Fernandez-Abascal J, et al. Int J Mol Sci. 2020 May 31;21(11):3955. doi: 10.3390/ijms21113955. Int J Mol Sci. 2020. PMID: 32486438 Free PMC article.
In order to study a possible role for CYP induction in neurorepair, we designed an in vitro model where undifferentiated neuroblastoma SH-SY5Y cells were treated with the CYP inducers beta-naphthoflavone (betaNF) and ethanol (EtOH) before and during exposure to the …
In order to study a possible role for CYP induction in neurorepair, we designed an in vitro model where undifferentiated neuroblastoma SH-SY …
Beta-naphthoflavone and doxorubicin synergistically enhance apoptosis in human lung cancer cells by inducing doxorubicin accumulation, mitochondrial ROS generation, and JNK pathway signaling.
Hoang DH, Song M, Kovale LM, Tran QH, Choe W, Kang I, Kim SS, Ha J. Hoang DH, et al. Biochem Biophys Res Commun. 2022 Dec 20;635:37-45. doi: 10.1016/j.bbrc.2022.10.015. Epub 2022 Oct 5. Biochem Biophys Res Commun. 2022. PMID: 36257190
In the present study, we examined the therapeutic potential of beta-naphthoflavone (BNF), a synthetic derivative of a naturally occurring flavonoid, in combination with doxorubicin for the treatment of lung cancer. ...BNF further exhibited synergistic inducti …
In the present study, we examined the therapeutic potential of beta-naphthoflavone (BNF), a synthetic derivative of a naturall …
Effects of rilpivirine, 17beta-estradiol and beta-naphthoflavone on the inflammatory status of release of adipocytokines in 3T3-L1 adipocytes in vitro.
Behl S, Adem A, Hussain A, Singh J. Behl S, et al. Mol Biol Rep. 2019 Jun;46(3):2643-2655. doi: 10.1007/s11033-019-04671-4. Epub 2019 Mar 29. Mol Biol Rep. 2019. PMID: 30927158
Rilpivirine is a non-nucleoside reverse transcriptase inhibitor, recently developed as a drug of choice for initial anti-retroviral (ARV) treatment of HIV-1 infection, whereas estradiol is a major component of hormonal contraceptives. Both drugs have effects on lipid metab …
Rilpivirine is a non-nucleoside reverse transcriptase inhibitor, recently developed as a drug of choice for initial anti-retroviral (ARV) tr …
616 results