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Sequence diversity between class I MHC loci of African native and introduced Bos taurus cattle in Theileria parva endemic regions: in silico peptide binding prediction identifies distinct functional clusters.
Obara I, Nielsen M, Jeschek M, Nijhof A, Mazzoni CJ, Svitek N, Steinaa L, Awino E, Olds C, Jabbar A, Clausen PH, Bishop RP. Obara I, et al. Immunogenetics. 2016 May;68(5):339-52. doi: 10.1007/s00251-016-0902-5. Epub 2016 Feb 6. Immunogenetics. 2016. PMID: 26852329
The functional competency of class I MHC genes is dependent on the presence of codons specifying certain critical amino acid residues that line the peptide binding groove. Compared with European Bos taurus in which class I MHC allelic polymorphisms have been examine …
The functional competency of class I MHC genes is dependent on the presence of codons specifying certain critical amino acid residues that l …
In vivo comparison of susceptibility between Bos indicus and Bos taurus cattle types to Theileria parva infection.
Ndungu SG, Brown CG, Dolan TT. Ndungu SG, et al. Onderstepoort J Vet Res. 2005 Mar;72(1):13-22. Onderstepoort J Vet Res. 2005. PMID: 15991702
The objective of this study was to determine whether Bos taurus cattle differ form Bos indicus in their susceptibility to infection with the Muguga stabilate of Theileria parva and in their resistance to the resultant disease. Ten Friesians (B. …
The objective of this study was to determine whether Bos taurus cattle differ form Bos indicus in their susceptibility …
Deciphering the kinome of Theileria annulata for identification of drug targets and anti-theilerial drug.
Kar PP, Araveti PB, Srivastava A. Kar PP, et al. Ticks Tick Borne Dis. 2022 Sep 29;13(6):102049. doi: 10.1016/j.ttbdis.2022.102049. Online ahead of print. Ticks Tick Borne Dis. 2022. PMID: 36215767
Three protein kinases, TA16570, TA09820, and TA07000, had <40% identity with Bos taurus and >40% identity with the previously identified potential drug targets present in the Therapeutic Target Database (TTD). ...Only Dabrafenib, out of these 5 drugs, could bi …
Three protein kinases, TA16570, TA09820, and TA07000, had <40% identity with Bos taurus and >40% identity with the previ …
Antigen gene and variable number tandem repeat (VNTR) diversity in Theileria parva parasites from Ankole cattle in south-western Uganda: Evidence for conservation in antigen gene sequences combined with extensive polymorphism at VNTR loci.
Nanteza A, Obara I, Kasaija P, Mwega E, Kabi F, Salih DA, Njahira M, Njuguna J, Odongo D, Bishop RP, Skilton RA, Ahmed J, Clausen PH, Lubega GW. Nanteza A, et al. Transbound Emerg Dis. 2020 Mar;67 Suppl 1:99-107. doi: 10.1111/tbed.13311. Transbound Emerg Dis. 2020. PMID: 32174038
Theileria parva is a tick-transmitted apicomplexan protozoan parasite that infects lymphocytes of cattle and African Cape buffalo (Syncerus caffer), causing a frequently fatal disease of cattle in eastern, central and southern Africa. ...This study investigated the
Theileria parva is a tick-transmitted apicomplexan protozoan parasite that infects lymphocytes of cattle and African Cape buff
The response of Bos taurus and Bos indicus cattle types to inoculation of lymphoblastoid cell lines infected with Theileria parva schizonts.
Dolan TT, Njuguna LN, Stagg DA. Dolan TT, et al. Tropenmed Parasitol. 1982 Mar;33(1):57-62. Tropenmed Parasitol. 1982. PMID: 6808728
In a preliminary experiment eight Bos indicus type cattle were inoculated with 10(9) cells of a Bos taurus lymphoblastoid cell line infected with Theileria parva schizonts. ...Two Bos taurus type cattle receiving Bos taur
In a preliminary experiment eight Bos indicus type cattle were inoculated with 10(9) cells of a Bos taurus lymphoblasto …
A Theileria parva isolate of low virulence infects a subpopulation of lymphocytes.
Tindih HS, Geysen D, Goddeeris BM, Awino E, Dobbelaere DA, Naessens J. Tindih HS, et al. Infect Immun. 2012 Mar;80(3):1267-73. doi: 10.1128/IAI.05085-11. Epub 2011 Dec 27. Infect Immun. 2012. PMID: 22202119 Free PMC article.
Theileria parva is a tick-transmitted protozoan parasite that infects and transforms bovine lymphocytes. We have previously shown that Theileria parva Chitongo is an isolate with a lower virulence than that of T. parva Muguga. ...
Theileria parva is a tick-transmitted protozoan parasite that infects and transforms bovine lymphocytes. We have previously sh
CD4 T Cell Responses to Theileria parva in Immune Cattle Recognize a Diverse Set of Parasite Antigens Presented on the Surface of Infected Lymphoblasts.
Morrison WI, Aguado A, Sheldrake TA, Palmateer NC, Ifeonu OO, Tretina K, Parsons K, Fenoy E, Connelley T, Nielsen M, Silva JC. Morrison WI, et al. J Immunol. 2021 Oct 15;207(8):1965-1977. doi: 10.4049/jimmunol.2100331. Epub 2021 Sep 10. J Immunol. 2021. PMID: 34507950
Parasite-specific CD8 T cell responses play a key role in mediating immunity against Theileria parva in cattle (Bos taurus), and there is evidence that efficient induction of these responses requires CD4 T cell responses. ...The results of this study p …
Parasite-specific CD8 T cell responses play a key role in mediating immunity against Theileria parva in cattle (Bos
Relationship between burden of infection in ungulate populations and wildlife/livestock interfaces.
Caron A, Miguel E, Gomo C, Makaya P, Pfukenyi DM, Foggin C, Hove T, de Garine-Wichatitsky M. Caron A, et al. Epidemiol Infect. 2013 Jul;141(7):1522-35. doi: 10.1017/S0950268813000204. Epub 2013 Feb 26. Epidemiol Infect. 2013. PMID: 23442901 Free PMC article.
Here, we assessed the infection burdens of sympatric domestic cattle (Bos taurus/Bos indicus) and African buffalo (Syncerus caffer) at an unfenced interface and compared the infection burdens of cattle populations at different wildlife/livestock interfaces in …
Here, we assessed the infection burdens of sympatric domestic cattle (Bos taurus/Bos indicus) and African buffalo (Sync …
Synergistic Effect of Two Nanotechnologies Enhances the Protective Capacity of the Theileria parva Sporozoite p67C Antigen in Cattle.
Lacasta A, Mody KT, De Goeyse I, Yu C, Zhang J, Nyagwange J, Mwalimu S, Awino E, Saya R, Njoroge T, Muriuki R, Ndiwa N, Poole EJ, Zhang B, Cavallaro A, Mahony TJ, Steinaa L, Mitter N, Nene V. Lacasta A, et al. J Immunol. 2021 Feb 15;206(4):686-699. doi: 10.4049/jimmunol.2000442. Epub 2021 Jan 8. J Immunol. 2021. PMID: 33419770 Free PMC article.
East Coast fever (ECF), caused by Theileria parva, is the most important tick-borne disease of cattle in sub-Saharan Africa. ...Individually, HBcAg-p67C (chimeric hepatitis B core Ag virus-like particles displaying p67C) and silica vesicle (SV)-p67C (s-p67C adsorbed …
East Coast fever (ECF), caused by Theileria parva, is the most important tick-borne disease of cattle in sub-Saharan Africa. . …
Exposure of Ankole and crossbred cattle to theileriosis in Rwanda.
Paling RW, Mpangala C, Luttikhuizen B, Sibomana G. Paling RW, et al. Trop Anim Health Prod. 1991 Nov;23(4):203-14. doi: 10.1007/BF02357101. Trop Anim Health Prod. 1991. PMID: 1796523
Susceptible Ankole (Sanga: Bos indicus/Bos taurus) and crossbred Ankole x Jersey (B. taurus) and Ankole x Sahiwal (B. indicus) cattle derived from a farm in Rwanda with no recent history of theileriosis, were infected with Theileria parva
Susceptible Ankole (Sanga: Bos indicus/Bos taurus) and crossbred Ankole x Jersey (B. taurus) and Ankole x Sahiwa …
14 results