Skip to main page content
Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

MyNCBI Filters
Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2014 1
2017 1
2018 1
2020 0
Text availability
Article attribute
Article type
Publication date

Search Results

3 results
Results by year
Filters applied: . Clear all
Page 1
11C-cetrozole: an improved C-11C-methylated PET probe for aromatase imaging in the brain.
Takahashi K, et al. J Nucl Med 2014. PMID 24676756 Free article.
RESULTS: In vitro and in vivo studies using (11)C-cetrozole showed its superiority in brain aromatase imaging in terms of specificity and selectivity, compared with previously developed (11)C-vorozole. ...High specific binding of (11)C-cetrozole was observed in the amygdala and hypothalamus, and we also noted binding in the nucleus accumbens of rhesus monkeys for the first time. ...
RESULTS: In vitro and in vivo studies using (11)C-cetrozole showed its superiority in brain aromatase imaging in terms of specificity …
Association between aromatase in human brains and personality traits
Takahashi K, et al. Sci Rep 2018. PMID 30442903 Free PMC article.
We performed a positron emission tomography (PET) study in 21 healthy subjects using (11)C-cetrozole, which has high selectivity and affinity for aromatase. ...A strong accumulation of (11)C-cetrozole was detected in the thalamus, hypothalamus, amygdala, and medulla. Females showed associations between aromatase levels in subcortical regions, such as the amygdala and supraoptic nucleus of the hypothalamus, and personality traits such as aggression, novelty seeking, and self-transcendence. ...
We performed a positron emission tomography (PET) study in 21 healthy subjects using (11)C-cetrozole, which has high selectivity and …
Comparison of pharmacokinetics of newly discovered aromatase inhibitors by a cassette microdosing approach in healthy Japanese subjects
Kusuhara H, et al. Drug Metab Pharmacokinet 2017 - Clinical Trial. PMID 29137842
A cocktail of cetrozole and TMD-322 was administered intravenously or orally (1.98 μg for each drug) to six healthy volunteers in a crossover fashion. ...Two subjects out of six exhibited 4- and 17-fold larger exposure of cetrozole than the others following intravenous and oral administration, respectively. ...
A cocktail of cetrozole and TMD-322 was administered intravenously or orally (1.98 μg for each drug) to six healthy volunteers in a c …
Feedback