Genetic Hearing Loss Associated With Autoinflammation.
Nakanishi H, Prakash P, Ito T, Kim HJ, Brewer CC, Harrow D, Roux I, Hosokawa S, Griffith AJ.
Nakanishi H, et al.
Front Neurol. 2020 Mar 5;11:141. doi: 10.3389/fneur.2020.00141. eCollection 2020.
Front Neurol. 2020.
PMID: 32194497
Free PMC article.
Review.
These observations led us to test the hypothesis that macrophage/monocyte-like cells in the cochlea can mediate local autoinflammation via activation of the NLRP3 inflammasome. The inflammasome can indeed be activated in macrophage/monocyte-like cells of the mouse cochl …
These observations led us to test the hypothesis that macrophage/monocyte-like cells in the cochlea can mediate local autoinflammatio …