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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1908 1
1936 1
1937 1
1938 3
1939 2
1940 7
1941 1
1942 4
1943 3
1945 9
1946 25
1947 22
1948 30
1949 19
1950 45
1951 60
1952 45
1953 50
1954 63
1955 73
1956 55
1957 68
1958 41
1959 43
1960 47
1961 40
1962 39
1963 123
1964 167
1965 118
1966 128
1967 132
1968 176
1969 193
1970 191
1971 248
1972 303
1973 284
1974 312
1975 385
1976 348
1977 349
1978 364
1979 389
1980 416
1981 429
1982 430
1983 407
1984 451
1985 435
1986 398
1987 412
1988 405
1989 450
1990 418
1991 411
1992 392
1993 373
1994 374
1995 382
1996 370
1997 356
1998 369
1999 361
2000 340
2001 320
2002 317
2003 331
2004 331
2005 337
2006 366
2007 347
2008 349
2009 342
2010 378
2011 398
2012 414
2013 413
2014 465
2015 448
2016 462
2017 470
2018 481
2019 509
2020 710
2021 843
2022 772
2023 685
2024 224

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22,890 results

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Page 1
Mechanism of action of colchicine in the treatment of gout.
Dalbeth N, Lauterio TJ, Wolfe HR. Dalbeth N, et al. Clin Ther. 2014 Oct 1;36(10):1465-79. doi: 10.1016/j.clinthera.2014.07.017. Epub 2014 Aug 21. Clin Ther. 2014. PMID: 25151572 Free article. Review.
PURPOSE: The aims of this article were to systematically review the literature about the mechanism of action of colchicine in the multimodal pathology of acute inflammation associated with gout and to consider the clinical utility of colchicine in other chronic infl …
PURPOSE: The aims of this article were to systematically review the literature about the mechanism of action of colchicine in the mul …
Colchicine in Neurosurgery.
Drosos E, Giakoumettis D, Themistocleous MS. Drosos E, et al. Curr Pharm Des. 2018;24(6):664-667. doi: 10.2174/1381612824666180115095715. Curr Pharm Des. 2018. PMID: 29336254 Review.
These characteristics have been the key to initiate colchicine as a preventive agent in vascular conditions. Furthermore, as colchicine is an antimitotic drug, it is currently being studied as a potential anti-glioma agent. However, the narrow therapeutic index of t …
These characteristics have been the key to initiate colchicine as a preventive agent in vascular conditions. Furthermore, as colch
Do all colchicine preparations have the same effectiveness in patients with familial Mediterranean fever?
Baglan E, Ozdel S, Bulbul M. Baglan E, et al. Mod Rheumatol. 2021 Mar;31(2):481-484. doi: 10.1080/14397595.2020.1790139. Epub 2020 Jul 20. Mod Rheumatol. 2021. PMID: 32613873
AIM: Colchicine is the primary treatment for familial Mediterranean fever (FMF). ...The daily colchicine dose and FMF attack frequency before and after switching from domestically produced (DP)-coated colchicine tablets to foreign produced (FP)-compressed …
AIM: Colchicine is the primary treatment for familial Mediterranean fever (FMF). ...The daily colchicine dose and FMF attack f …
Colchicine.
Wallace SL. Wallace SL. Semin Arthritis Rheum. 1974 Summer;3(4):369-81. doi: 10.1016/0049-0172(74)90006-7. Semin Arthritis Rheum. 1974. PMID: 4598037 Review. No abstract available.
Colchicine in Gout: An Update.
Pascart T, Richette P. Pascart T, et al. Curr Pharm Des. 2018;24(6):684-689. doi: 10.2174/1381612824999180115103951. Curr Pharm Des. 2018. PMID: 29336252 Review.
Despite the fact that colchicine is by far the most ancient treatment for gout, new data are still being gathered. In gout, colchicine's ability to block polymerization of tubulin prevents the activation of the inflammasome. ...
Despite the fact that colchicine is by far the most ancient treatment for gout, new data are still being gathered. In gout, colchi
Colchicine poisoning.
Hood RL. Hood RL. J Emerg Med. 1994 Mar-Apr;12(2):171-7. doi: 10.1016/0736-4679(94)90695-5. J Emerg Med. 1994. PMID: 8207152 Review.
Colchicine poisoning is an unusual but serious form of drug intoxication. ...Treatment requires early recognition and supportive care including fluid and electrolyte replacement and occasionally blood component replacement therapy. Recent experiments using colchicine
Colchicine poisoning is an unusual but serious form of drug intoxication. ...Treatment requires early recognition and supportive care
Colchicine today.
Niel E, Scherrmann JM. Niel E, et al. Joint Bone Spine. 2006 Dec;73(6):672-8. doi: 10.1016/j.jbspin.2006.03.006. Epub 2006 Sep 1. Joint Bone Spine. 2006. PMID: 17067838 Review.
Three proteins play pivotal roles in colchicine pharmacokinetics: the colchicine receptor, tubulin, which governs the plasma elimination half-life of the drug; intestinal and hepatic CYP3A4, which is key to the biotransformation of colchicine; and P-glycoprot …
Three proteins play pivotal roles in colchicine pharmacokinetics: the colchicine receptor, tubulin, which governs the plasma e …
Colchicine in dermatology: A review.
Robinson KP, Chan JJ. Robinson KP, et al. Australas J Dermatol. 2018 Nov;59(4):278-285. doi: 10.1111/ajd.12795. Epub 2018 Feb 12. Australas J Dermatol. 2018. PMID: 29430631 Review.
Despite its efficacy in various cutaneous diseases, the use of colchicine may be limited by concerns over its side-effects and the potential for toxicity. This article reviews the current literature on the pharmacology of colchicine and its clinical applications in …
Despite its efficacy in various cutaneous diseases, the use of colchicine may be limited by concerns over its side-effects and the po …
Upstream biomanufacturing of pharmaceutical colchicine.
Sivakumar G. Sivakumar G. Crit Rev Biotechnol. 2018 Feb;38(1):83-92. doi: 10.1080/07388551.2017.1312269. Epub 2017 Apr 12. Crit Rev Biotechnol. 2018. PMID: 28399663 Review.
The plant-based colchicine potentially affects major diseases such as cardiovascular events, cancers and gout. ...Consequently, developing sustainable upstream industrial colchicine biofactories is imperative, especially in curtailing drug costs. ...
The plant-based colchicine potentially affects major diseases such as cardiovascular events, cancers and gout. ...Consequently, devel …
Colchicine: 1998 update.
Ben-Chetrit E, Levy M. Ben-Chetrit E, et al. Semin Arthritis Rheum. 1998 Aug;28(1):48-59. doi: 10.1016/s0049-0172(98)80028-0. Semin Arthritis Rheum. 1998. PMID: 9726336 Review.
The drug may be given to children with FMF. The efficacy of colchicine has been proved in FMF, gout, Behcet's disease, and cirrhosis. ...Gastrointestinal side effects occur early and are most common manifestations of colchicine toxicity. Severe colchicine tox …
The drug may be given to children with FMF. The efficacy of colchicine has been proved in FMF, gout, Behcet's disease, and cirrhosis. …
22,890 results
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