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Quoted phrase not found in phrase index: "steoroids"
Page 1
RIFM fragrance ingredient safety assessment, decanoic acid, CAS Registry Number 334-48-5.
Api AM, Belsito D, Biserta S, Botelho D, Bruze M, Burton GA Jr, Buschmann J, Cancellieri MA, Dagli ML, Date M, Dekant W, Deodhar C, Fryer AD, Gadhia S, Jones L, Joshi K, Lapczynski A, Lavelle M, Liebler DC, Na M, O'Brien D, Patel A, Penning TM, Ritacco G, Rodriguez-Ropero F, Romine J, Sadekar N, Salvito D, Schultz TW, Siddiqi F, Sipes IG, Sullivan G, Thakkar Y, Tokura Y, Tsang S. Api AM, et al. Food Chem Toxicol. 2020 Oct 15;144 Suppl 1:111465. doi: 10.1016/j.fct.2020.111465. Epub 2020 Jul 5. Food Chem Toxicol. 2020. PMID: 32640335 Review.
The existing information supports the use of this material as described in this safety assessment. Decanoic acid was evaluated for genotoxicity, repeated dose toxicity, reproductive toxicity, local respiratory toxicity, phototoxicity/photoallergenicity, skin …
The existing information supports the use of this material as described in this safety assessment. Decanoic acid was evaluated …
Decanoic Acid Stimulates Autophagy in D. discoideum.
Warren EC, Kramár P, Lloyd-Jones K, Williams RSB. Warren EC, et al. Cells. 2021 Oct 29;10(11):2946. doi: 10.3390/cells10112946. Cells. 2021. PMID: 34831171 Free PMC article.
Here, we utilize this model to analyze a role for MCFAs in regulating autophagy. We show that treatment with decanoic acid but not octanoic acid induces autophagosome formation and modulates autophagic flux in high glucose conditions. To investigate this effect, …
Here, we utilize this model to analyze a role for MCFAs in regulating autophagy. We show that treatment with decanoic acid but …
Gut Microbiota-Decanoic Acid-Interleukin-17A Axis Orchestrates Hyperglycemia-Induced Osteoporosis in Male Mice.
Jiang T, Li C, Pan Z, Wang Y, Chen X, Song J, Zhu K, Yang Y, Hou Y, Sun L, Zhao H, Liu J, Gu Y, Tao B. Jiang T, et al. Diabetes. 2026 Jan 1;75(1):154-165. doi: 10.2337/db25-0471. Diabetes. 2026. PMID: 41144501
Decanoic acid promoted the differentiation of naive CD4+ T cells into T helper17 cells, leading to increased IL-17A production. These findings reveal a microbiome dysbiosis-driven decanoic acid/IL-17A axis in HG-induced osteoporosis and highlight the t …
Decanoic acid promoted the differentiation of naive CD4+ T cells into T helper17 cells, leading to increased IL-17A production …
Decanoic Acid Exerts Its Anti-Tumor Effects via Targeting c-Met Signaling Cascades in Hepatocellular Carcinoma Model.
Yang MH, Lee M, Deivasigamani A, Le DD, Mohan CD, Hui KM, Sethi G, Ahn KS. Yang MH, et al. Cancers (Basel). 2023 Sep 22;15(19):4681. doi: 10.3390/cancers15194681. Cancers (Basel). 2023. PMID: 37835375 Free PMC article.
Aberrant activation of c-Met can modulate tumor growth and progression in HCC. Here, we report that DA exhibited pro-found anti-tumor effects on human HCC through the suppression of HGF/c-Met signaling cascades in vitro and in vivo. ...DA induced apoptotic cell deat …
Aberrant activation of c-Met can modulate tumor growth and progression in HCC. Here, we report that DA exhibited pro-found anti-tu …
Alleviation of Limosilactobacillus reuteri in polycystic ovary syndrome protects against circadian dysrhythmia-induced dyslipidemia via capric acid and GALR1 signaling.
Li S, Zhai J, Chu W, Geng X, Wang D, Jiao L, Lu G, Chan WY, Sun K, Sun Y, Chen ZJ, Du Y. Li S, et al. NPJ Biofilms Microbiomes. 2023 Jul 8;9(1):47. doi: 10.1038/s41522-023-00415-2. NPJ Biofilms Microbiomes. 2023. PMID: 37422471 Free PMC article.
Knowledge gaps that limit the development of therapies for polycystic ovary syndrome (PCOS) concern various environmental factors that impact clinical characteristics. Circadian dysrhythmia contributes to glycometabolic and reproductive hallmarks of PCOS. Here, we i …
Knowledge gaps that limit the development of therapies for polycystic ovary syndrome (PCOS) concern various environmental factors tha …
The medium-chain fatty acid decanoic acid reduces oxidative stress levels in neuroblastoma cells.
Mett J, Müller U. Mett J, et al. Sci Rep. 2021 Mar 17;11(1):6135. doi: 10.1038/s41598-021-85523-9. Sci Rep. 2021. PMID: 33731759 Free PMC article.
Phosphatidylcholine (PC) containing decanoic acid (10:0) (PC10:0/10:0) reduced the cellular H(2)O(2) release in comparison to solvent, L-alpha-Glycerophosphorylcholine and PC containing the long-chain fatty acid (LCFA) arachidic acid (20:0). ...It did not affect the …
Phosphatidylcholine (PC) containing decanoic acid (10:0) (PC10:0/10:0) reduced the cellular H(2)O(2) release in comparison to …
Decanoic acid suppresses proliferation and invasiveness of human trophoblast cells by disrupting mitochondrial function.
Yang C, Lim W, Bazer FW, Song G. Yang C, et al. Toxicol Appl Pharmacol. 2018 Jan 15;339:121-132. doi: 10.1016/j.taap.2017.12.009. Epub 2017 Dec 14. Toxicol Appl Pharmacol. 2018. PMID: 29248464
Decanoic acid (DA) is a medium-chain fatty acid used in the manufacture of various products including plastics, cosmetics, and lubricants. ...Collectively, these results suggest that personal products containing DA will have harmful effects on human trophoblasts, an …
Decanoic acid (DA) is a medium-chain fatty acid used in the manufacture of various products including plastics, cosmetics, and …
Lipidomic Biomarkers in Polycystic Ovary Syndrome and Endometrial Cancer.
Shafiee MN, Ortori CA, Barrett DA, Mongan NP, Abu J, Atiomo W. Shafiee MN, et al. Int J Mol Sci. 2020 Jul 3;21(13):4753. doi: 10.3390/ijms21134753. Int J Mol Sci. 2020. PMID: 32635401 Free PMC article.
Women with polycystic ovary syndrome (PCOS) are more likely to develop endometrial cancer (EC). The molecular mechanisms which increase the risk of EC in PCOS are unclear. ...
Women with polycystic ovary syndrome (PCOS) are more likely to develop endometrial cancer (EC). The molecular mechanisms which …
Kinetic Characterization of Human Histone Deacetylase 8 With Medium-Chain Fatty Acyl Lysine.
Yoo H, Polsinelli GA. Yoo H, et al. Epigenet Insights. 2021 Dec 10;14:25168657211065685. doi: 10.1177/25168657211065685. eCollection 2021. Epigenet Insights. 2021. PMID: 34917889 Free PMC article.
HDACs are considered targets for the treatment of cancer due to their role in regulating transcription. HDAC8 inhibition may be an important anti-proliferative factor for histone deacetylase inhibitors on cancer cells and may give rise to the progression of apoptosi …
HDACs are considered targets for the treatment of cancer due to their role in regulating transcription. HDAC8 inhibition may be an im …
Exposure to endocrine-disrupting chemicals and risk of gestational hypertension and preeclampsia: A systematic review and meta-analysis.
Hirke A, Varghese B, Varade S, Adela R. Hirke A, et al. Environ Pollut. 2023 Jan 15;317:120828. doi: 10.1016/j.envpol.2022.120828. Epub 2022 Dec 5. Environ Pollut. 2023. PMID: 36481468
Prenatal exposure to endocrine-disrupting chemicals has been linked to gestational hypertension (GH) and preeclampsia (PE). ...There was no significant association observed with perfluoro hexane sulfonic acid (PFHxS), perfluoro decanoic acid (PFDA), perfluoro …
Prenatal exposure to endocrine-disrupting chemicals has been linked to gestational hypertension (GH) and preeclampsia (PE). ...There …
161 results