"drozitumab"[nm] - Search Results

Year	Number of Results
2010	1
2011	2
2012	1
2013	5
2014	1
2015	1
2016	3
2017	2
2024	0

1

Doxorubicin overcomes resistance to drozitumab by antagonizing Inhibitor of Apoptosis Proteins (IAPs).

Zinonos I, Labrinidis A, Liapis V, Hay S, Panagopoulos V, Denichilo M, Ponomarev V, Ingman W, Atkins GJ, Findlay DM, Zannettino AC, Evdokiou A. Zinonos I, et al. Anticancer Res. 2014 Dec;34(12):7007-20. Anticancer Res. 2014. PMID: 25503127

2

The TRAIL receptor agonist drozitumab targets basal B triple-negative breast cancer cells that express vimentin and Axl.

Dine JL, O'Sullivan CC, Voeller D, Greer YE, Chavez KJ, Conway CM, Sinclair S, Stone B, Amiri-Kordestani L, Merchant AS, Hewitt SM, Steinberg SM, Swain SM, Lipkowitz S. Dine JL, et al. Breast Cancer Res Treat. 2016 Jan;155(2):235-51. doi: 10.1007/s10549-015-3673-z. Epub 2016 Jan 12. Breast Cancer Res Treat. 2016. PMID: 26759246 Free PMC article.

3

Development of a bioassay as a measure of drozitumab-mediated apoptosis induced by soluble Fc gamma receptors.

Shim J, Huang A, Miller AS. Shim J, et al. J Immunol Methods. 2017 Sep;448:26-33. doi: 10.1016/j.jim.2017.05.004. Epub 2017 May 12. J Immunol Methods. 2017. PMID: 28506821

4

Drozitumab, a human antibody to death receptor 5, has potent antitumor activity against rhabdomyosarcoma with the expression of caspase-8 predictive of response.

Kang Z, Chen JJ, Yu Y, Li B, Sun SY, Zhang B, Cao L. Kang Z, et al. Clin Cancer Res. 2011 May 15;17(10):3181-92. doi: 10.1158/1078-0432.CCR-10-2874. Epub 2011 Mar 8. Clin Cancer Res. 2011. PMID: 21385927 Free PMC article.

5

Pre-activation of the p53 pathway through Nutlin-3a sensitises sarcomas to drozitumab therapy.

Pishas KI, Neuhaus SJ, Clayer MT, Adwal A, Brown MP, Evdokiou A, Callen DF, Neilsen PM. Pishas KI, et al. Oncol Rep. 2013 Jul;30(1):471-7. doi: 10.3892/or.2013.2454. Epub 2013 May 13. Oncol Rep. 2013. PMID: 23670273

6

Identification of RIP1 as a critical mediator of Smac mimetic-mediated sensitization of glioblastoma cells for Drozitumab-induced apoptosis.

Cristofanon S, Abhari BA, Krueger M, Tchoghandjian A, Momma S, Calaminus C, Vucic D, Pichler BJ, Fulda S. Cristofanon S, et al. Cell Death Dis. 2015 Apr 16;6(4):e1724. doi: 10.1038/cddis.2014.592. Cell Death Dis. 2015. PMID: 25880091 Free PMC article.

7

Phase Ib study of drozitumab combined with first-line mFOLFOX6 plus bevacizumab in patients with metastatic colorectal cancer.

Rocha Lima CM, Bayraktar S, Flores AM, MacIntyre J, Montero A, Baranda JC, Wallmark J, Portera C, Raja R, Stern H, Royer-Joo S, Amler LC. Rocha Lima CM, et al. Cancer Invest. 2012 Dec;30(10):727-31. doi: 10.3109/07357907.2012.732163. Epub 2012 Oct 12. Cancer Invest. 2012. PMID: 23061802 Clinical Trial.

8

Death receptors as targets in cancer.

Micheau O, Shirley S, Dufour F. Micheau O, et al. Br J Pharmacol. 2013 Aug;169(8):1723-44. doi: 10.1111/bph.12238. Br J Pharmacol. 2013. PMID: 23638798 Free PMC article. Review.

9

Anticancer efficacy of the hypoxia-activated prodrug evofosfamide is enhanced in combination with proapoptotic receptor agonists against osteosarcoma.

Liapis V, Zysk A, DeNichilo M, Zinonos I, Hay S, Panagopoulos V, Shoubridge A, Difelice C, Ponomarev V, Ingman W, Atkins GJ, Findlay DM, Zannettino ACW, Evdokiou A. Liapis V, et al. Cancer Med. 2017 Sep;6(9):2164-2176. doi: 10.1002/cam4.1115. Epub 2017 Aug 10. Cancer Med. 2017. PMID: 28799237 Free PMC article.

10

An Fcγ receptor-dependent mechanism drives antibody-mediated target-receptor signaling in cancer cells.

Wilson NS, Yang B, Yang A, Loeser S, Marsters S, Lawrence D, Li Y, Pitti R, Totpal K, Yee S, Ross S, Vernes JM, Lu Y, Adams C, Offringa R, Kelley B, Hymowitz S, Daniel D, Meng G, Ashkenazi A. Wilson NS, et al. Cancer Cell. 2011 Jan 18;19(1):101-13. doi: 10.1016/j.ccr.2010.11.012. Cancer Cell. 2011. PMID: 21251615 Free article.

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