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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2004 2
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2008 5
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2011 74
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2013 186
2014 268
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2017 504
2018 700
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2024 641

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Page 1
Drug repurposing: progress, challenges and recommendations.
Pushpakom S, Iorio F, Eyers PA, Escott KJ, Hopper S, Wells A, Doig A, Guilliams T, Latimer J, McNamee C, Norris A, Sanseau P, Cavalla D, Pirmohamed M. Pushpakom S, et al. Nat Rev Drug Discov. 2019 Jan;18(1):41-58. doi: 10.1038/nrd.2018.168. Epub 2018 Oct 12. Nat Rev Drug Discov. 2019. PMID: 30310233 Review.
Various data-driven and experimental approaches have been suggested for the identification of repurposable drug candidates; however, there are also major technological and regulatory challenges that need to be addressed. In this Review, we present approaches used for drug
Various data-driven and experimental approaches have been suggested for the identification of repurposable drug candidates; however, there a …
Drug Repurposing for Rare Diseases.
Roessler HI, Knoers NVAM, van Haelst MM, van Haaften G. Roessler HI, et al. Trends Pharmacol Sci. 2021 Apr;42(4):255-267. doi: 10.1016/j.tips.2021.01.003. Epub 2021 Feb 6. Trends Pharmacol Sci. 2021. PMID: 33563480 Review.
The process of repurposing drugs for new indications, compared with the development of novel orphan drugs, is a time-saving and cost-efficient method resulting in higher success rates, which can therefore drastically reduce the risk of drug development for rare diseases. Although …
The process of repurposing drugs for new indications, compared with the development of novel orphan drugs, is a time-saving and cost-efficie …
Machine and deep learning approaches for cancer drug repurposing.
Issa NT, Stathias V, Schürer S, Dakshanamurthy S. Issa NT, et al. Semin Cancer Biol. 2021 Jan;68:132-142. doi: 10.1016/j.semcancer.2019.12.011. Epub 2020 Jan 3. Semin Cancer Biol. 2021. PMID: 31904426 Free PMC article. Review.
As the cost of developing a new drug remains prohibitively expensive, repurposing of existing approved and investigational drugs is sought after given known safety profiles and reduction in the cost barrier. Notably, successes in oncologic drug repurposing have been …
As the cost of developing a new drug remains prohibitively expensive, repurposing of existing approved and investigational drugs is sought a …
Drug repurposing: a promising tool to accelerate the drug discovery process.
Parvathaneni V, Kulkarni NS, Muth A, Gupta V. Parvathaneni V, et al. Drug Discov Today. 2019 Oct;24(10):2076-2085. doi: 10.1016/j.drudis.2019.06.014. Epub 2019 Jun 22. Drug Discov Today. 2019. PMID: 31238113 Review.
It is necessary to discover new strategies for reducing the drug discovery time frame. Today, drug repurposing has gained importance in identifying new therapeutic uses for already-available drugs. ...Numerous strategies to discover new indications for FDA-approved …
It is necessary to discover new strategies for reducing the drug discovery time frame. Today, drug repurposing has gained impo …
Drug Repurposing in Human Cancers.
Grassi G, Grassi M. Grassi G, et al. Curr Med Chem. 2020;27(42):7213. doi: 10.2174/092986732742201105104417. Curr Med Chem. 2020. PMID: 33342397 No abstract available.
Editorial: Drug Repurposing.
Pantziarka P, André N. Pantziarka P, et al. Front Med (Lausanne). 2019 Jul 3;6:154. doi: 10.3389/fmed.2019.00154. eCollection 2019. Front Med (Lausanne). 2019. PMID: 31334237 Free PMC article. No abstract available.
Drug repurposing for stroke intervention.
Ghosh D, Sehgal K, Sodnar B, Bhosale N, Sarmah D, Datta A, Chaudhary A, Kalia K, Wang X, Bhattacharya P. Ghosh D, et al. Drug Discov Today. 2022 Jul;27(7):1974-1982. doi: 10.1016/j.drudis.2022.03.003. Epub 2022 Mar 4. Drug Discov Today. 2022. PMID: 35257857 Review.
Additionally, poststroke rehabilitation therapies can provide functional recovery but take a long time to show benefits. Drug repurposing could be a novel approach to broaden treatment options in this scenario. ...
Additionally, poststroke rehabilitation therapies can provide functional recovery but take a long time to show benefits. Drug repu
Drug repurposing in cancer.
Sleire L, Førde HE, Netland IA, Leiss L, Skeie BS, Enger PØ. Sleire L, et al. Pharmacol Res. 2017 Oct;124:74-91. doi: 10.1016/j.phrs.2017.07.013. Epub 2017 Jul 13. Pharmacol Res. 2017. PMID: 28712971 Review.
This unmet need for more effective anti-cancer drugs has sparked a growing interest for drug repurposing, i.e. using drugs already approved for other indications to treat cancer. ...Whereas some of them induce cancer cell death or suppress various aspects of cancer …
This unmet need for more effective anti-cancer drugs has sparked a growing interest for drug repurposing, i.e. using drugs alr …
10,306 results
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