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9 results

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Page 1
Parkinson's disease: a dual-hit hypothesis.
Hawkes CH, Del Tredici K, Braak H. Hawkes CH, et al. Neuropathol Appl Neurobiol. 2007 Dec;33(6):599-614. doi: 10.1111/j.1365-2990.2007.00874.x. Epub 2007 Oct 24. Neuropathol Appl Neurobiol. 2007. PMID: 17961138 Free PMC article. Review.
Early sites of Lewy pathology are the olfactory bulb and enteric plexus of the stomach. We propose that a neurotropic pathogen, probably viral, enters the brain via two routes: (i) nasal, with anterograde progression into the temporal lobe; and (ii) gastric, seconda …
Early sites of Lewy pathology are the olfactory bulb and enteric plexus of the stomach. We propose that a neurotropic pathogen …
The RET gene encodes RET protein, which triggers intracellular signaling pathways for enteric neurogenesis, and RET mutation results in Hirschsprung's disease.
Bhattarai C, Poudel PP, Ghosh A, Kalthur SG. Bhattarai C, et al. AIMS Neurosci. 2022 Mar 16;9(1):128-149. doi: 10.3934/Neuroscience.2022008. eCollection 2022. AIMS Neurosci. 2022. PMID: 35434281 Free PMC article. Review.
After migration, they proliferate and differentiate into the enteric plexus. Expression of the Rearranged During Transfection (RET) gene and its protein RET plays a crucial role in the formation of enteric neurons. ...
After migration, they proliferate and differentiate into the enteric plexus. Expression of the Rearranged During Transfection …
TNFalpha: a trigger of autonomic dysfunction.
Hermann GE, Rogers RC. Hermann GE, et al. Neuroscientist. 2008 Feb;14(1):53-67. doi: 10.1177/1073858407305725. Epub 2007 Oct 2. Neuroscientist. 2008. PMID: 17911224 Free PMC article. Review.
In response, the efferent elements (i.e., dorsal motor neurons of the vagus) cause gastroinhibition via their action on the gastric enteric plexus. We find that TNF alpha presynaptically modulates the release of glutamate from primary vagal afferents to the NST and …
In response, the efferent elements (i.e., dorsal motor neurons of the vagus) cause gastroinhibition via their action on the gastric enter …
Prostaglandin E2 receptors and their role in gastrointestinal motility - Potential therapeutic targets.
Heeney A, Rogers AC, Mohan H, Mc Dermott F, Baird AW, Winter DC. Heeney A, et al. Prostaglandins Other Lipid Mediat. 2021 Feb;152:106499. doi: 10.1016/j.prostaglandins.2020.106499. Epub 2020 Oct 6. Prostaglandins Other Lipid Mediat. 2021. PMID: 33035691 Review.
The recent discovery of four PGE(2) receptor subtypes in intestinal muscle layers as well as in the enteric plexus has led to much interest in the study of their roles in gut motility. Gut dysmotility has been implicated in functional disease processes including irr …
The recent discovery of four PGE(2) receptor subtypes in intestinal muscle layers as well as in the enteric plexus has led to …
[Lewy bodies, a misleading marker for Parkinson's disease?].
Duyckaerts C, Hauw JJ. Duyckaerts C, et al. Bull Acad Natl Med. 2003;187(2):277-92; discussion 292-3. Bull Acad Natl Med. 2003. PMID: 14556441 Review. French.
Lewy bodies and neurites are indeed to be found in many areas of the central and peripheral nervous system: stellate ganglia, cardiac and enteric plexus, pigmented nuclei of the brainstem, basal nucleus of Meynert, amygdala, limbic nuclei of the thalamus, parahippoc …
Lewy bodies and neurites are indeed to be found in many areas of the central and peripheral nervous system: stellate ganglia, cardiac and …
Surgical Techniques for the Treatment of Hirschsprung's Disease-A Historical Systematic Review and Current Status Quo.
Hager J, Sergi CM. Hager J, et al. Ann Ital Chir. 2025 Oct 29;96(12):1592-1612. doi: 10.62713/aic.3943. Ann Ital Chir. 2025. PMID: 41399224
AIM: Hirschsprung's disease, or aganglionosis of the colon, is a congenital disease characterized by a lack of neurons in the enteric plexus of the large bowel due to either migration failure or defective differentiation of neural crest cells. ...
AIM: Hirschsprung's disease, or aganglionosis of the colon, is a congenital disease characterized by a lack of neurons in the enteric …
Organization of the vagus in elasmobranchs: its bearing on a primitive gnathostome condition.
Sperry DG, Boord RL. Sperry DG, et al. Acta Anat (Basel). 1993;148(2-3):150-9. doi: 10.1159/000147534. Acta Anat (Basel). 1993. PMID: 8109197 Review.
Motoneurons that supply the branchial muscles of somitic origin are only located in the rostral segmented portion of the dorsal motor column. Preganglionic parasympathetics to the enteric plexus, presumably derived from circumpharyngeal crest, form the caudal portio …
Motoneurons that supply the branchial muscles of somitic origin are only located in the rostral segmented portion of the dorsal motor column …
Therapeutic proposals for the treatment of idiopathic constipation.
Sàez LR. Sàez LR. Ital J Gastroenterol. 1991 Nov;23(8 Suppl 1):30-5. Ital J Gastroenterol. 1991. PMID: 1661627 Review.
There are many conditions in which medical therapy fails its objective: in these cases it is important to exclude other causes of constipation (i.e. drug-related constipation, endocrine disorders, metabolic diseases, systemic illnesses or lesion of the enteric plexus …
There are many conditions in which medical therapy fails its objective: in these cases it is important to exclude other causes of constipati …
Antiepileptic drug formulation and treatment in the elderly: biopharmaceutical considerations.
Gidal BE. Gidal BE. Int Rev Neurobiol. 2007;81:299-311. doi: 10.1016/S0074-7742(06)81020-2. Int Rev Neurobiol. 2007. PMID: 17433933 Review.
Oral administration of AEDs may be affected by changes associated with aging, including altered oral protective reflexes, xerostomia, thickening of the esophageal smooth muscle layer, reduced contraction velocity and duration, altered esophageal emptying rates, and enteric …
Oral administration of AEDs may be affected by changes associated with aging, including altered oral protective reflexes, xerostomia, thicke …