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Year Number of Results
1976 1
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1983 1
1986 1
1988 3
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1990 4
1991 5
1992 2
1994 6
1995 1
1996 11
1997 2
1998 2
1999 9
2000 4
2001 4
2002 11
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2004 8
2005 16
2006 7
2007 12
2008 10
2009 11
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327 results

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Page 1
Epicardium in Heart Development.
Cao Y, Duca S, Cao J. Cao Y, et al. Cold Spring Harb Perspect Biol. 2020 Feb 3;12(2):a037192. doi: 10.1101/cshperspect.a037192. Cold Spring Harb Perspect Biol. 2020. PMID: 31451510 Free PMC article. Review.
The epicardium, the outermost tissue layer that envelops all vertebrate hearts, plays a crucial role in cardiac development and regeneration and has been implicated in potential strategies for cardiac repair. The heterogenous cell population that composes the epicardium
The epicardium, the outermost tissue layer that envelops all vertebrate hearts, plays a crucial role in cardiac development and regen …
The epicardium as a hub for heart regeneration.
Cao J, Poss KD. Cao J, et al. Nat Rev Cardiol. 2018 Oct;15(10):631-647. doi: 10.1038/s41569-018-0046-4. Nat Rev Cardiol. 2018. PMID: 29950578 Free PMC article. Review.
The epicardium is essential for muscle regeneration in the zebrafish model of innate heart regeneration, and the epicardium also participates in fibrotic responses in mammalian hearts. ...In this Review, we describe recent advances in our understanding of the biolog …
The epicardium is essential for muscle regeneration in the zebrafish model of innate heart regeneration, and the epicardium al …
The Role of the Epicardium During Heart Development and Repair.
Quijada P, Trembley MA, Small EM. Quijada P, et al. Circ Res. 2020 Jan 31;126(3):377-394. doi: 10.1161/CIRCRESAHA.119.315857. Epub 2020 Jan 30. Circ Res. 2020. PMID: 31999538 Free PMC article. Review.
Although the epicardium becomes dormant after birth, cardiac injury reactivates developmental gene programs that stimulate epithelial-to-mesenchymal transition; however, it is not clear how the epicardium contributes to disease progression or repair in the adult. In …
Although the epicardium becomes dormant after birth, cardiac injury reactivates developmental gene programs that stimulate epithelial …
Epicardium-derived fibroblasts in heart development and disease.
Fang M, Xiang FL, Braitsch CM, Yutzey KE. Fang M, et al. J Mol Cell Cardiol. 2016 Feb;91:23-7. doi: 10.1016/j.yjmcc.2015.12.019. Epub 2015 Dec 22. J Mol Cell Cardiol. 2016. PMID: 26718723 Free PMC article. Review.
The majority of cardiac fibroblasts in a mature mammalian heart are derived from the epicardium during prenatal development and reactivate developmental programs during the progression of fibrotic disease. ...Here we review cellular and molecular mechanisms that control …
The majority of cardiac fibroblasts in a mature mammalian heart are derived from the epicardium during prenatal development and react …
The epicardium as a candidate for heart regeneration.
Smart N, Riley PR. Smart N, et al. Future Cardiol. 2012 Jan;8(1):53-69. doi: 10.2217/fca.11.87. Future Cardiol. 2012. PMID: 22185446 Free PMC article. Review.
There is an urgent need, therefore, to develop novel therapies for myocardial and coronary vascular regeneration. The epicardium-derived cells present a tractable resident progenitor source with the potential to stimulate neovasculogenesis and contribute de novo cardiomyoc …
There is an urgent need, therefore, to develop novel therapies for myocardial and coronary vascular regeneration. The epicardium-deri …
Novel Insights into the Molecular Mechanisms Governing Embryonic Epicardium Formation.
Carmona R, López-Sánchez C, Garcia-Martinez V, Garcia-López V, Muñoz-Chápuli R, Lozano-Velasco E, Franco D. Carmona R, et al. J Cardiovasc Dev Dis. 2023 Oct 24;10(11):440. doi: 10.3390/jcdd10110440. J Cardiovasc Dev Dis. 2023. PMID: 37998498 Free PMC article. Review.
The embryonic epicardium originates from the proepicardium, an extracardiac primordium constituted by a cluster of mesothelial cells. In early embryos, the embryonic epicardium is characterized by a squamous cell epithelium resting on the myocardium surface. ...
The embryonic epicardium originates from the proepicardium, an extracardiac primordium constituted by a cluster of mesothelial cells. …
Myocardial regeneration: role of epicardium and implicated genes.
Saifi O, Ghandour B, Jaalouk D, Refaat M, Mahfouz R. Saifi O, et al. Mol Biol Rep. 2019 Dec;46(6):6661-6674. doi: 10.1007/s11033-019-05075-0. Epub 2019 Sep 23. Mol Biol Rep. 2019. PMID: 31549371 Review.
Studies investigated the underlying mechanism of myocardial regeneration in species capable to do so, to see its applicability on mammals. The epicardium, the mesothelial outer layer of the vertebrate heart, has proven to play an important role in the process of repair and …
Studies investigated the underlying mechanism of myocardial regeneration in species capable to do so, to see its applicability on mammals. T …
The Epicardium in Ventricular Septation During Evolution and Development.
Poelmann RE, Jensen B, Bartelings MM, Richardson MK, Gittenberger-de Groot AC. Poelmann RE, et al. 2016 Jun 25. In: Nakanishi T, Markwald RR, Baldwin HS, Keller BB, Srivastava D, Yamagishi H, editors. Etiology and Morphogenesis of Congenital Heart Disease: From Gene Function and Cellular Interaction to Morphology [Internet]. Tokyo: Springer; 2016. Chapter 13. 2016 Jun 25. In: Nakanishi T, Markwald RR, Baldwin HS, Keller BB, Srivastava D, Yamagishi H, editors. Etiology and Morphogenesis of Congenital Heart Disease: From Gene Function and Cellular Interaction to Morphology [Internet]. Tokyo: Springer; 2016. Chapter 13. PMID: 29787105 Free Books & Documents. Review.
The epicardium has several essential functions in development of cardiac architecture and differentiation of the myocardium in vertebrates. We uncovered a novel function of the epicardium in species with partial or complete ventricular septation including reptiles, …
The epicardium has several essential functions in development of cardiac architecture and differentiation of the myocardium in verteb …
Role of the Epicardium in the Development of the Atrioventricular Valves and Its Relevance to the Pathogenesis of Myxomatous Valve Disease.
Wolters R, Deepe R, Drummond J, Harvey AB, Hiriart E, Lockhart MM, van den Hoff MJB, Norris RA, Wessels A. Wolters R, et al. J Cardiovasc Dev Dis. 2021 May 12;8(5):54. doi: 10.3390/jcdd8050054. J Cardiovasc Dev Dis. 2021. PMID: 34066253 Free PMC article. Review.
We provide an overview of critical events in the development of the atrioventricular junction, discuss the role of the epicardium in these events, and illustrate how interfering with molecular mechanisms that are involved in the epicardial-dependent formation of the atriov …
We provide an overview of critical events in the development of the atrioventricular junction, discuss the role of the epicardium in …
The epicardium as a source of multipotent adult cardiac progenitor cells: Their origin, role and fate.
Smits AM, Dronkers E, Goumans MJ. Smits AM, et al. Pharmacol Res. 2018 Jan;127:129-140. doi: 10.1016/j.phrs.2017.07.020. Epub 2017 Jul 24. Pharmacol Res. 2018. PMID: 28751220 Free article. Review.
Targeting an endogenous stem cell population could circumvent these limitations. The epicardium, a membranous layer covering the outside of the myocardium, is an accessible cell population which plays a key role in the developing heart. ...Furthermore, paracrine communicat …
Targeting an endogenous stem cell population could circumvent these limitations. The epicardium, a membranous layer covering the outs …
327 results