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Quoted phrase not found in phrase index: "epithelial layer of mucosa of larynx"
Page 1
Mucins and the Microbiome.
Hansson GC. Hansson GC. Annu Rev Biochem. 2020 Jun 20;89:769-793. doi: 10.1146/annurev-biochem-011520-105053. Epub 2020 Apr 3. Annu Rev Biochem. 2020. PMID: 32243763 Free PMC article. Review.
The general functions of mucins on internal epithelial surfaces are to wash away microorganisms and, even more importantly, to build protective barriers. The latter function is most evident in the large intestine, where the inner mucus layer separates the numerous c …
The general functions of mucins on internal epithelial surfaces are to wash away microorganisms and, even more importantly, to build …
Intestinal mucus barrier: A potential therapeutic target for IBD.
Qiao Y, He C, Xia Y, Ocansey DKW, Mao F. Qiao Y, et al. Autoimmun Rev. 2025 Jan 31;24(2):103717. doi: 10.1016/j.autrev.2024.103717. Epub 2024 Dec 9. Autoimmun Rev. 2025. PMID: 39662652 Review.
Unlike the small intestine, where the mucus layer is a single layer, the colonic mucus layer can be divided into a sterile inner layer and an outer layer with bacterial colonization. ...This review highlights the important role of the mucus l …
Unlike the small intestine, where the mucus layer is a single layer, the colonic mucus layer can be divided into a ster …
The mucus and mucins of the goblet cells and enterocytes provide the first defense line of the gastrointestinal tract and interact with the immune system.
Pelaseyed T, Bergström JH, Gustafsson JK, Ermund A, Birchenough GM, Schütte A, van der Post S, Svensson F, Rodríguez-Piñeiro AM, Nyström EE, Wising C, Johansson ME, Hansson GC. Pelaseyed T, et al. Immunol Rev. 2014 Jul;260(1):8-20. doi: 10.1111/imr.12182. Immunol Rev. 2014. PMID: 24942678 Free PMC article. Review.
In the large intestine, the inner mucus layer separates the commensal bacteria from the host epithelium. The outer colonic mucus layer is the natural habitat for the commensal bacteria. ...One example of this is IL10 that can affect and improve the properties of the …
In the large intestine, the inner mucus layer separates the commensal bacteria from the host epithelium. The outer colonic mucus l …
Immune Regulation of Goblet Cell and Mucus Functions in Health and Disease.
Gustafsson JK, Hansson GC. Gustafsson JK, et al. Annu Rev Immunol. 2025 Apr;43(1):169-189. doi: 10.1146/annurev-immunol-101721-065224. Epub 2025 Jan 3. Annu Rev Immunol. 2025. PMID: 39752567 Free article. Review.
The mucosal surfaces of the body are the most vulnerable points for infection because they are lined by single or multiple layers of very active epithelial cells. The main protector of these cells is the mucus system generated by the specialized goblet cell secretin …
The mucosal surfaces of the body are the most vulnerable points for infection because they are lined by single or multiple layers of …
Intestinal Macromolecular Transport Supporting Adaptive Immunity.
Kulkarni DH, Newberry RD. Kulkarni DH, et al. Cell Mol Gastroenterol Hepatol. 2019;7(4):729-737. doi: 10.1016/j.jcmgh.2019.01.003. Epub 2019 Jan 30. Cell Mol Gastroenterol Hepatol. 2019. PMID: 30710727 Free PMC article. Review.
The gastrointestinal tract performs opposing functions of nutrient absorption, barrier maintenance, and the delivery of luminal substances for the appropriate induction of tolerogenic or protective adaptive immunity. The single-layer epithelium lining the gastrointestinal …
The gastrointestinal tract performs opposing functions of nutrient absorption, barrier maintenance, and the delivery of luminal substances f …
Development and Functional Properties of Intestinal Mucus Layer in Poultry.
Duangnumsawang Y, Zentek J, Goodarzi Boroojeni F. Duangnumsawang Y, et al. Front Immunol. 2021 Oct 4;12:745849. doi: 10.3389/fimmu.2021.745849. eCollection 2021. Front Immunol. 2021. PMID: 34671361 Free PMC article. Review.
Intestinal mucus plays important roles in protecting the epithelial surfaces against pathogens, supporting the colonization with commensal bacteria, maintaining an appropriate environment for digestion, as well as facilitating nutrient transport from the lumen to the under …
Intestinal mucus plays important roles in protecting the epithelial surfaces against pathogens, supporting the colonization with comm …
Mucins Dynamics in Physiological and Pathological Conditions.
Melhem H, Regan-Komito D, Niess JH. Melhem H, et al. Int J Mol Sci. 2021 Dec 20;22(24):13642. doi: 10.3390/ijms222413642. Int J Mol Sci. 2021. PMID: 34948435 Free PMC article. Review.
Maintaining intestinal health requires clear segregation between epithelial cells and luminal microbes. The intestinal mucus layer, produced by goblet cells (GCs), is a key element in maintaining the functional protection of the epithelium. ...Furthermore, numerous …
Maintaining intestinal health requires clear segregation between epithelial cells and luminal microbes. The intestinal mucus layer …
Mucus and the goblet cell.
Johansson ME, Hansson GC. Johansson ME, et al. Dig Dis. 2013;31(3-4):305-9. doi: 10.1159/000354683. Epub 2013 Nov 14. Dig Dis. 2013. PMID: 24246979 Free PMC article. Review.
The discovery of an inner mucus layer normally impervious to bacteria has changed our way of understanding the interaction between commensal bacteria and the host epithelial cells. ...In the absence of MUC2 mucin, there is no inner mucus layer and bacteria re …
The discovery of an inner mucus layer normally impervious to bacteria has changed our way of understanding the interaction between co …
Gastrointestinal epithelial innate immunity-regionalization and organoids as new model.
Kayisoglu Ö, Schlegel N, Bartfeld S. Kayisoglu Ö, et al. J Mol Med (Berl). 2021 Apr;99(4):517-530. doi: 10.1007/s00109-021-02043-9. Epub 2021 Feb 4. J Mol Med (Berl). 2021. PMID: 33538854 Free PMC article. Review.
At the centre of the interaction lies the epithelial layer, which marks the boundaries of the body. It is equipped with a multitude of different innate immune sensors, such as Toll-like receptors, to mount inflammatory responses to microbes. ...In addition, organoid …
At the centre of the interaction lies the epithelial layer, which marks the boundaries of the body. It is equipped with a mult …
Neural control of goblet cells in the gastrointestinal tract.
Rowe MC, Pettersson VL, Carbone SE, Gustafsson JK, Poole DP. Rowe MC, et al. Am J Physiol Gastrointest Liver Physiol. 2025 Oct 1;329(4):G513-G535. doi: 10.1152/ajpgi.00191.2025. Epub 2025 Aug 18. Am J Physiol Gastrointest Liver Physiol. 2025. PMID: 40824870 Free article. Review.
The mucus layer is an essential physical barrier that protects and lubricates mucosal surfaces in the body. ...Goblet cells (GCs) are specialized epithelial cells with a classical role to synthesize and secrete mucus to maintain the mucus layer. ...
The mucus layer is an essential physical barrier that protects and lubricates mucosal surfaces in the body. ...Goblet cells (GCs) are …
26 results