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Quoted phrase not found in phrase index: "ethyl methylcarbamate"
Page 1
Protolysis kinetics of ethyl N-methylcarbamate.
Martinelli LC, Blanton CD, Whidby JF. Martinelli LC, et al. J Phys Chem. 1971 Jun 10;75(12):1895-8. doi: 10.1021/j100681a023. J Phys Chem. 1971. PMID: 5135352 No abstract available.
Discovery of 1-(phenylsulfonyl)-1H-indole-based multifunctional ligands targeting cholinesterases and 5-HT6 receptor with anti-aggregation properties against amyloid-beta and tau.
Wichur T, Pasieka A, Godyń J, Panek D, Góral I, Latacz G, Honkisz-Orzechowska E, Bucki A, Siwek A, Głuch-Lutwin M, Knez D, Brazzolotto X, Gobec S, Kołaczkowski M, Sabate R, Malawska B, Więckowska A. Wichur T, et al. Eur J Med Chem. 2021 Dec 5;225:113783. doi: 10.1016/j.ejmech.2021.113783. Epub 2021 Aug 19. Eur J Med Chem. 2021. PMID: 34461507 Free article.
Compound 17, a tacrine derivative is a reversible inhibitor of acetyl- and butyrylcholinesterase (IC(50) = 8 nM and IC(50) = 24 nM respectively), while compound 35 with rivastigmine-derived phenyl N-ethyl-N-methylcarbamate fragment is a selective, pseudo-irre …
Compound 17, a tacrine derivative is a reversible inhibitor of acetyl- and butyrylcholinesterase (IC(50) = 8 nM and IC(50) = 24 nM respectiv …
Differences between rodents and humans in the metabolic toxification of N,N-dimethylformamide.
Mráz J, Cross H, Gescher A, Threadgill MD, Flek J. Mráz J, et al. Toxicol Appl Pharmacol. 1989 May;98(3):507-16. doi: 10.1016/0041-008x(89)90179-8. Toxicol Appl Pharmacol. 1989. PMID: 2718177
The metabolites, which were quantified by gas chromatography (GC) are N-(hydroxymethyl)-N-methylformamide (HMMF), which yielded N-methylformamide on GC analysis, a species which decomposed to formamide on GC analysis, and N-acetyl-S-(N-methylcarbamoyl) cysteine (AMCC), measured a …
The metabolites, which were quantified by gas chromatography (GC) are N-(hydroxymethyl)-N-methylformamide (HMMF), which yielded N-methylform …
Determination of N-acetyl-S-(N-methylcarbamoyl)cysteine (AMCC) in the general population using gas chromatography-mass spectrometry.
Käfferlein HU, Angerer J. Käfferlein HU, et al. J Environ Monit. 1999 Oct;1(5):465-9. doi: 10.1039/a903039e. J Environ Monit. 1999. PMID: 11529165
During the preparation of the samples, AMCC is converted to ethyl-N-methylcarbamate (EMC) in the presence of anhydrous potassium carbonate (K2CO3) and ethanol. ...
During the preparation of the samples, AMCC is converted to ethyl-N-methylcarbamate (EMC) in the presence of anhydrous …
Gas chromatographic method for the determination of N-acetyl-S-(N-methylcarbamoyl)cysteine, a metabolite of N,N-dimethylformamide and N-methylformamide, in human urine.
Mráz J. Mráz J. J Chromatogr. 1988 Oct 14;431(2):361-8. doi: 10.1016/s0378-4347(00)83104-7. J Chromatogr. 1988. PMID: 3243790
Treatment of a urine sample (1 ml) with ethanol (2 ml) and potassium carbonate (1.5 g) produces ethyl N-methylcarbamate, which is extracted into ethanol and measured by packed column gas chromatography with nitrogen-sensitive detection. ...
Treatment of a urine sample (1 ml) with ethanol (2 ml) and potassium carbonate (1.5 g) produces ethyl N-methylcarbamate
N-alkylformamides are metabolized to N-alkylcarbamoylating species by hepatic microsomes from rodents and humans.
Cross H, Dayal R, Hyland R, Gescher A. Cross H, et al. Chem Res Toxicol. 1990 Jul-Aug;3(4):357-62. doi: 10.1021/tx00016a014. Chem Res Toxicol. 1990. PMID: 2133085
NMF was incubated with microsomes or cytosol obtained from BALB/c mice, and metabolically generated N-methyl-carbamoylating species were analyzed after derivatization with ethanol in base to furnish ethyl N-methylcarbamate. Generation of metabolite was cataly …
NMF was incubated with microsomes or cytosol obtained from BALB/c mice, and metabolically generated N-methyl-carbamoylating species were ana …
Simultaneous determination of two human urinary metabolites of N,N-dimethylformamide using gas chromatography-thermionic sensitive detection with mass spectrometric confirmation.
Käfferlein HU, Angerer J. Käfferlein HU, et al. J Chromatogr B Biomed Sci Appl. 1999 Nov 12;734(2):285-98. doi: 10.1016/s0378-4347(99)00372-2. J Chromatogr B Biomed Sci Appl. 1999. PMID: 10595726
During clean-up, AMCC is converted into ethyl-N-methylcarbamate (EMC), and during gas chromatography, HMMF is degraded in the injector to N-methylformamide (NMF). ...
During clean-up, AMCC is converted into ethyl-N-methylcarbamate (EMC), and during gas chromatography, HMMF is degraded …