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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1947 1
1970 2
1971 4
1972 5
1973 1
1974 1
1975 1
1976 4
1977 1
1979 1
1980 3
1981 5
1982 8
1983 6
1984 25
1985 37
1986 35
1987 41
1988 45
1989 62
1990 148
1991 167
1992 260
1993 408
1994 712
1995 1045
1996 1199
1997 1397
1998 1646
1999 1936
2000 2489
2001 2383
2002 2437
2003 2437
2004 2404
2005 2587
2006 2442
2007 2334
2008 2323
2009 2225
2010 2305
2011 2487
2012 2480
2013 2531
2014 2808
2015 2918
2016 3002
2017 3057
2018 3154
2019 3212
2020 3047
2021 13
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Search Results

59,582 results
Results by year
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Page 1
History of gene therapy.
Wirth T, Parker N, Ylä-Herttuala S. Wirth T, et al. Gene. 2013 Aug 10;525(2):162-9. doi: 10.1016/j.gene.2013.03.137. Epub 2013 Apr 23. Gene. 2013. PMID: 23618815 Review.
Two decades after the initial gene therapy trials and more than 1700 approved clinical trials worldwide we not only have gained much new information and knowledge regarding gene therapy in general, but also learned to understand the concern that has pe …
Two decades after the initial gene therapy trials and more than 1700 approved clinical trials worldwide we not only have gaine …
Gene therapy for neurological disorders.
Choong CJ, Baba K, Mochizuki H. Choong CJ, et al. Expert Opin Biol Ther. 2016;16(2):143-59. doi: 10.1517/14712598.2016.1114096. Epub 2015 Dec 5. Expert Opin Biol Ther. 2016. PMID: 26642082 Review.
Gene therapy involves either the introduction of a replacement allele into cells to compensate for loss of gene function or the silencing of dominant mutant allele that is pathologic to cells. AREAS COVERED: This review discusses the currently available ge
Gene therapy involves either the introduction of a replacement allele into cells to compensate for loss of gene functio
Gene Therapy for Parkinson's Disease, An Update.
Axelsen TM, Woldbye DPD. Axelsen TM, et al. J Parkinsons Dis. 2018;8(2):195-215. doi: 10.3233/JPD-181331. J Parkinsons Dis. 2018. PMID: 29710735 Free PMC article. Review.
The field of gene therapy offers a potential means to improve current therapy. The present review gives an update of the present status of gene therapy for PD. ...As alternative types of gene therapy, opto- and chemogenetics might …
The field of gene therapy offers a potential means to improve current therapy. The present review gives an update of th …
Gene therapy returns to centre stage.
Naldini L. Naldini L. Nature. 2015 Oct 15;526(7573):351-60. doi: 10.1038/nature15818. Nature. 2015. PMID: 26469046 Review.
Recent clinical trials of gene therapy have shown remarkable therapeutic benefits and an excellent safety record. They provide evidence for the long-sought promise of gene therapy to deliver 'cures' for some otherwise terminal or severely disabling con …
Recent clinical trials of gene therapy have shown remarkable therapeutic benefits and an excellent safety record. They provide …
Gene Therapy for Autoimmune Disease.
Shu SA, Wang J, Tao MH, Leung PS. Shu SA, et al. Clin Rev Allergy Immunol. 2015 Oct;49(2):163-76. doi: 10.1007/s12016-014-8451-x. Clin Rev Allergy Immunol. 2015. PMID: 25277817 Review.
Advances in understanding the immunological and molecular basis of autoimmune diseases have made gene therapy a promising approach to treat the affected patients. ...The ultimate goal of gene therapy is to restore and maintain the immune tolerance to t …
Advances in understanding the immunological and molecular basis of autoimmune diseases have made gene therapy a promising appr …
Pharmaceutical Development of AAV-Based Gene Therapy Products for the Eye.
Rodrigues GA, Shalaev E, Karami TK, Cunningham J, Slater NKH, Rivers HM. Rodrigues GA, et al. Pharm Res. 2018 Dec 27;36(2):29. doi: 10.1007/s11095-018-2554-7. Pharm Res. 2018. PMID: 30591984 Free PMC article. Review.
A resurgence of interest and investment in the field of gene therapy, driven in large part by advances in viral vector technology, has recently culminated in United States Food and Drug Administration approval of the first gene therapy product targetin …
A resurgence of interest and investment in the field of gene therapy, driven in large part by advances in viral vector technol …
Tumor angiogenesis and anti-angiogenic gene therapy for cancer.
Li T, Kang G, Wang T, Huang H. Li T, et al. Oncol Lett. 2018 Jul;16(1):687-702. doi: 10.3892/ol.2018.8733. Epub 2018 May 17. Oncol Lett. 2018. PMID: 29963134 Free PMC article. Review.
Among them, anti-angiogenic gene therapy has received attention due to its apparent advantages. Although specific problems remain prior to cancer being fully curable using anti-angiogenic gene therapy, several methods have been explored, and progress h …
Among them, anti-angiogenic gene therapy has received attention due to its apparent advantages. Although specific problems rem …
Gene Therapy.
Thorne B, Takeya R, Vitelli F, Swanson X. Thorne B, et al. Adv Biochem Eng Biotechnol. 2018;165:351-399. doi: 10.1007/10_2016_53. Adv Biochem Eng Biotechnol. 2018. PMID: 28289769 Review.
Gene therapy refers to a rapidly growing field of medicine in which genes are introduced into the body to treat or prevent diseases. ...In addition, a case study of an industry-scale cGMP production of an AAV-based gene therapy product performed at 2,0
Gene therapy refers to a rapidly growing field of medicine in which genes are introduced into the body to treat or prevent dis
Viral Vectors for Gene Therapy: Current State and Clinical Perspectives.
Lukashev AN, Zamyatnin AA Jr. Lukashev AN, et al. Biochemistry (Mosc). 2016 Jul;81(7):700-8. doi: 10.1134/S0006297916070063. Biochemistry (Mosc). 2016. PMID: 27449616 Free article. Review.
Gene therapy is the straightforward approach for the application of recent advances in molecular biology into clinical practice. ...The relatively simple organization of viruses, small genome size, and evolutionary plasticity allow modifying them to create effective
Gene therapy is the straightforward approach for the application of recent advances in molecular biology into clinical practic
Gene Therapy in Head and Neck Cancer.
Farmer ZL, Kim ES, Carrizosa DR. Farmer ZL, et al. Oral Maxillofac Surg Clin North Am. 2019 Feb;31(1):117-124. doi: 10.1016/j.coms.2018.08.006. Epub 2018 Oct 25. Oral Maxillofac Surg Clin North Am. 2019. PMID: 30454787 Review.
One potential treatment avenue is the use of gene therapy. This article provides insight into some gene therapy targets and varied techniques being evaluated for patients with head and neck cancer. Techniques include corrective gene therapy
One potential treatment avenue is the use of gene therapy. This article provides insight into some gene therapy
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