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78 results

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Page 1
The 'healthy smoker': a phenomenon of health selection?
Becklake MR, Lalloo U. Becklake MR, et al. Respiration. 1990;57(3):137-44. doi: 10.1159/000195837. Respiration. 1990. PMID: 2274712 Review.
Despite the wealth of published data on the topic of lung function in relation to the smoking habit, much is presented in a way which does not permit the concept of the 'healthy smoker' to be addressed. Nevertheless, this review revealed sufficient evidence from cro …
Despite the wealth of published data on the topic of lung function in relation to the smoking habit, much is presented in a way which does n …
Analysis of the lung microbiome in the "healthy" smoker and in COPD.
Erb-Downward JR, Thompson DL, Han MK, Freeman CM, McCloskey L, Schmidt LA, Young VB, Toews GB, Curtis JL, Sundaram B, Martinez FJ, Huffnagle GB. Erb-Downward JR, et al. PLoS One. 2011 Feb 22;6(2):e16384. doi: 10.1371/journal.pone.0016384. PLoS One. 2011. PMID: 21364979 Free PMC article. Clinical Trial.
Meta-analysis of sputum microbiome studies identifies airway disease-specific taxonomic and functional signatures.
Ghosh A, Saha S. Ghosh A, et al. J Med Microbiol. 2022 Dec;72(12). doi: 10.1099/jmm.0.001617. J Med Microbiol. 2022. PMID: 36748565
Shannon's index (alpha diversity) of the healthy smoker group was the highest among all. The beta diversity showed that the sputum microbiome is distinct in major airway diseases such as asthma, COPD and cystic fibrosis. ...
Shannon's index (alpha diversity) of the healthy smoker group was the highest among all. The beta diversity showed that the sp …
Evaluation of apoptosis and hypoxia-related factors in gingival tissues of smoker and non-smoker periodontitis patients.
Karatas O, Balci Yuce H, Tulu F, Taskan MM, Gevrek F, Toker H. Karatas O, et al. J Periodontal Res. 2020 Jun;55(3):392-399. doi: 10.1111/jre.12723. Epub 2019 Dec 19. J Periodontal Res. 2020. PMID: 31854460
METHODS: Gingival biopsy samples from 15 systemically and orally healthy individuals (Group 1), 15 systemically healthy periodontitis patients (Group 2), 15 systemically and orally healthy smokers (Group 3), and 15 systemically healthy smoker periodontitis patients …
METHODS: Gingival biopsy samples from 15 systemically and orally healthy individuals (Group 1), 15 systemically healthy periodontitis patien …
Oxidative stress triggers Itch-mediated TXNIP degradation and NF-κB activation promoting chronic obstructive pulmonary disease.
Lin PY, Lee KY, Ho SC, Chuang HC, Su BH, Wu YJ, Tseng PC, Tsai TT, Lin CF, Satria RD, Shih FC, Chen CL. Lin PY, et al. Respir Res. 2025 Oct 17;26(1):286. doi: 10.1186/s12931-025-03369-5. Respir Res. 2025. PMID: 41107933 Free PMC article.
In vivo, lung tissues from mice exposed to whole-body cigarette smoke (CS) for 12 weeks, as well as clinical samples from healthy non-smokers, a healthy smoker, and COPD patients, were analyzed. RESULTS: Our findings demonstrated that thioredoxin-interacting protein …
In vivo, lung tissues from mice exposed to whole-body cigarette smoke (CS) for 12 weeks, as well as clinical samples from healthy non-smoker …
Nucleic acid sensor STING drives remodeling and its inhibition enhances steroid responsiveness in chronic obstructive pulmonary disease.
Mdkhana B, Saheb Sharif-Askari N, Ramakrishnan RK, Al-Sheakly BK, Hafezi S, Saheb Sharif-Askari F, Bajbouj K, Hamid Q, Halwani R. Mdkhana B, et al. PLoS One. 2023 Jul 5;18(7):e0284061. doi: 10.1371/journal.pone.0284061. eCollection 2023. PLoS One. 2023. PMID: 37406004 Free PMC article.
METHODS: Primary cultured lung fibroblasts were isolated from healthy non-smoker, healthy smoker, and smoker COPD individuals. The expression of STING pathway, remodeling, and steroid resistance signatures were investigated in these fibroblasts upon LPS stimulation …
METHODS: Primary cultured lung fibroblasts were isolated from healthy non-smoker, healthy smoker, and smoker COPD individuals. …
Using Hyperpolarized Xenon-129 MRI to Quantify Early-Stage Lung Disease in Smokers.
Ruppert K, Qing K, Patrie JT, Altes TA, Mugler JP 3rd. Ruppert K, et al. Acad Radiol. 2019 Mar;26(3):355-366. doi: 10.1016/j.acra.2018.11.005. Epub 2018 Dec 3. Acad Radiol. 2019. PMID: 30522808 Free PMC article.
RESULTS: In healthy never smokers the septal wall thickness increased by 0.04 mum per year of age. The healthy smoker cohort exhibited normal pulmonary function test measures that did not significantly differ from the never-smoker cohort. ...
RESULTS: In healthy never smokers the septal wall thickness increased by 0.04 mum per year of age. The healthy smoker cohort e …
78 results