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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1962 1
1972 1
1975 1
1980 1
1986 1
2003 2
2004 1
2005 4
2006 3
2007 3
2008 2
2010 1
2012 2
2013 3
2014 5
2016 2
2017 1
2018 2
2019 3
2020 0
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Page 1
The role of immune regulatory molecules in multiple sclerosis.
Afshar B, Khalifehzadeh-Esfahani Z, Seyfizadeh N, Rezaei Danbaran G, Hemmatzadeh M, Mohammadi H. Afshar B, et al. J Neuroimmunol. 2019 Dec 15;337:577061. doi: 10.1016/j.jneuroim.2019.577061. Epub 2019 Sep 5. J Neuroimmunol. 2019. PMID: 31520791 Review.
Multiple sclerosis (MS) is the most common demyelinating disease which mainly impacts the integrity of central nervous system (CNS). ...
Multiple sclerosis (MS) is the most common demyelinating disease which mainly impacts the integrity of central nervous system
Blood Levels of Co-inhibitory-Receptors: A Biomarker of Disease Prognosis in Multiple Sclerosis.
Lavon I, Heli C, Brill L, Charbit H, Vaknin-Dembinsky A. Lavon I, et al. Front Immunol. 2019 Apr 30;10:835. doi: 10.3389/fimmu.2019.00835. eCollection 2019. Front Immunol. 2019. PMID: 31134049 Free PMC article.
Based on this, we studied the potential of circulating co-inhibitory receptor levels as predictive biomarkers of multiple sclerosis outcome. ...LAG-3 levels were significantly higher in patients with low disability index vs. non-low disability index multiple
Based on this, we studied the potential of circulating co-inhibitory receptor levels as predictive biomarkers of multiple sclerosi
A Deficit of CEACAM-1-Expressing T Lymphocytes Supports Inflammation in Primary Progressive Multiple Sclerosis.
Piancone F, Saresella M, Marventano I, La Rosa F, Caputo D, Mendozzi L, Rovaris M, Clerici M. Piancone F, et al. J Immunol. 2019 Jul 1;203(1):76-83. doi: 10.4049/jimmunol.1801625. Epub 2019 May 29. J Immunol. 2019. PMID: 31142599 Free article.
The immune regulatory mechanisms that modulate Th1 and Th17 immune responses are altered in multiple sclerosis (MS). The inhibitory TIM-3/Gal-9 pathway, in particular, is impaired in primary progressive MS (PPMS). ...
The immune regulatory mechanisms that modulate Th1 and Th17 immune responses are altered in multiple sclerosis (MS). The inhib …
Multiple sclerosis and regulatory T cells.
Costantino CM, Baecher-Allan C, Hafler DA. Costantino CM, et al. J Clin Immunol. 2008 Nov;28(6):697-706. doi: 10.1007/s10875-008-9236-x. Epub 2008 Sep 2. J Clin Immunol. 2008. PMID: 18763026 Free PMC article. Review.
INTRODUCTION: Multiple sclerosis (MS) is a complex genetic disease characterized by chronic inflammation of the central nervous system (CNS). ...
INTRODUCTION: Multiple sclerosis (MS) is a complex genetic disease characterized by chronic inflammation of the central nervou …
Daclizumab high-yield process in relapsing-remitting multiple sclerosis (SELECTION): a multicentre, randomised, double-blind extension trial.
Giovannoni G, Gold R, Selmaj K, Havrdova E, Montalban X, Radue EW, Stefoski D, McNeill M, Amaravadi L, Sweetser M, Elkins J, O'Neill G; SELECTION Study Investigators. Giovannoni G, et al. Lancet Neurol. 2014 May;13(5):472-81. doi: 10.1016/S1474-4422(14)70039-0. Epub 2014 Mar 19. Lancet Neurol. 2014. PMID: 24656609 Clinical Trial.
BACKGROUND: In the SELECT trial, disease activity was reduced in patients with multiple sclerosis who received daclizumab high-yield process (HYP) for 52 weeks. ...These results support further assessment of daclizumab HYP for relapsing-remitting multiple
BACKGROUND: In the SELECT trial, disease activity was reduced in patients with multiple sclerosis who received daclizumab high …
Semaphorin4A and H-ferritin utilize Tim-1 on human oligodendrocytes: A novel neuro-immune axis.
Chiou B, Lucassen E, Sather M, Kallianpur A, Connor J. Chiou B, et al. Glia. 2018 Jul;66(7):1317-1330. doi: 10.1002/glia.23313. Epub 2018 Feb 19. Glia. 2018. PMID: 29457657 Free PMC article.
Furthermore, we show in a series of pilot studies that Sema4A is detectable in the CSF of multiple sclerosis patients and HIV-seropositive persons and can induce oligodendrocyte cell death. ...
Furthermore, we show in a series of pilot studies that Sema4A is detectable in the CSF of multiple sclerosis patients and HIV- …
Promotion of tissue inflammation by the immune receptor Tim-3 expressed on innate immune cells.
Anderson AC, Anderson DE, Bregoli L, Hastings WD, Kassam N, Lei C, Chandwaskar R, Karman J, Su EW, Hirashima M, Bruce JN, Kane LP, Kuchroo VK, Hafler DA. Anderson AC, et al. Science. 2007 Nov 16;318(5853):1141-3. doi: 10.1126/science.1148536. Science. 2007. PMID: 18006747 Free article.
A role for the TIM-3/GAL-9/BAT3 pathway in determining the clinical phenotype of multiple sclerosis.
Saresella M, Piancone F, Marventano I, La Rosa F, Tortorella P, Caputo D, Rovaris M, Clerici M. Saresella M, et al. FASEB J. 2014 Nov;28(11):5000-9. doi: 10.1096/fj.14-258194. Epub 2014 Aug 4. FASEB J. 2014. PMID: 25091272
Apoptosis of myelin basic protein (MBP)-specific T lymphocytes correlates with reduced rates of disease progression in multiple sclerosis (MS). ...
Apoptosis of myelin basic protein (MBP)-specific T lymphocytes correlates with reduced rates of disease progression in multiple sc
TIM-3 in autoimmunity.
Anderson AC, Anderson DE. Anderson AC, et al. Curr Opin Immunol. 2006 Dec;18(6):665-9. doi: 10.1016/j.coi.2006.09.009. Epub 2006 Oct 2. Curr Opin Immunol. 2006. PMID: 17011764 Review.
Most importantly, recent data suggest a novel paradigm in which dysregulation of the TIM-3-galectin-9 pathway could underlie chronic autoimmune disease states, such as multiple sclerosis....
Most importantly, recent data suggest a novel paradigm in which dysregulation of the TIM-3-galectin-9 pathway could underlie chronic autoimm …
Lack of TIM-3 immunoregulation in multiple sclerosis.
Yang L, Anderson DE, Kuchroo J, Hafler DA. Yang L, et al. J Immunol. 2008 Apr 1;180(7):4409-14. doi: 10.4049/jimmunol.180.7.4409. J Immunol. 2008. PMID: 18354161 Free article.
Multiple sclerosis (MS) is an inflammatory disease of the CNS white matter associated with T cell infiltrates and alterations of immune functions that can be measured in the peripheral immune system. ...
Multiple sclerosis (MS) is an inflammatory disease of the CNS white matter associated with T cell infiltrates and alterations
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