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Filters applied: . Clear all Quoted phrase not found in phrase index: "hybrid compounds of curcumin and melatonin"
Page 1
Management of oxidative stress and other pathologies in Alzheimer's disease.
Simunkova M, Alwasel SH, Alhazza IM, Jomova K, Kollar V, Rusko M, Valko M. Simunkova M, et al. Arch Toxicol. 2019 Sep;93(9):2491-2513. doi: 10.1007/s00204-019-02538-y. Epub 2019 Aug 22. Arch Toxicol. 2019. PMID: 31440798 Review.
Tacrine was the first AChE inhibitor to be introduced into clinical practice and has been frequently used for the design of multitarget-directed ligands. A number of hybrid compounds containing tacrine and structural moieties derived from natural sources such as fla …
Tacrine was the first AChE inhibitor to be introduced into clinical practice and has been frequently used for the design of multitarget-dire …
Curcumin/melatonin hybrid 5-(4-hydroxy-phenyl)-3-oxo-pentanoic acid [2-(5-methoxy-1H-indol-3-yl)-ethyl]-amide ameliorates AD-like pathology in the APP/PS1 mouse model.
Gerenu G, Liu K, Chojnacki JE, Saathoff JM, Martínez-Martín P, Perry G, Zhu X, Lee HG, Zhang S. Gerenu G, et al. ACS Chem Neurosci. 2015 Aug 19;6(8):1393-1399. doi: 10.1021/acschemneuro.5b00082. Epub 2015 May 4. ACS Chem Neurosci. 2015. PMID: 25893520 Free PMC article.
In our efforts to develop hybrid compounds of curcumin and melatonin as potential disease-modifying agents for Alzheimer's disease (AD), a potent lead hybrid compound, Z-CM-I-1, has been recently identified and biologically charact …
In our efforts to develop hybrid compounds of curcumin and melatonin as potential disease-modifying agents for A …
Discovery of 5-(4-hydroxyphenyl)-3-oxo-pentanoic acid [2-(5-methoxy-1H-indol-3-yl)-ethyl]-amide as a neuroprotectant for Alzheimer's disease by hybridization of curcumin and melatonin.
Chojnacki JE, Liu K, Yan X, Toldo S, Selden T, Estrada M, Rodríguez-Franco MI, Halquist MS, Ye D, Zhang S. Chojnacki JE, et al. ACS Chem Neurosci. 2014 Aug 20;5(8):690-9. doi: 10.1021/cn500081s. Epub 2014 May 22. ACS Chem Neurosci. 2014. PMID: 24825313 Free PMC article.
In our effort to develop effective neuroprotectants as potential treatments for Alzheimer's disease (AD), hybrid compounds of curcumin and melatonin, two natural products that have been extensively studied in various AD models, were designed, sy …
In our effort to develop effective neuroprotectants as potential treatments for Alzheimer's disease (AD), hybrid compounds
Melatonin as a versatile molecule to design novel multitarget hybrids against neurodegeneration.
Ramos E, Egea J, de Los Ríos C, Marco-Contelles J, Romero A. Ramos E, et al. Future Med Chem. 2017 May;9(8):765-780. doi: 10.4155/fmc-2017-0014. Epub 2017 May 12. Future Med Chem. 2017. PMID: 28498717 Review.
Melatonin is an indoleamine produced mainly in the pineal gland. The natural decline of melatonin levels with aging strongly contributes to the development of neurodegenerative disorders. ...This review focuses on a number of melatonin hybrids resultin
Melatonin is an indoleamine produced mainly in the pineal gland. The natural decline of melatonin levels with aging strongly c