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Adolescents and young adults with rhabdomyosarcoma treated in the European paediatric Soft tissue sarcoma Study Group (EpSSG) protocols: a cohort study.
Ferrari A, Chisholm JC, Jenney M, Minard-Colin V, Orbach D, Casanova M, Guillen G, Glosli H, van Rijn RR, Schoot RA, Cameron AL, Rogers T, Alaggio R, Ben-Arush M, Mandeville HC, Devalck C, Defachelles AS, Coppadoro B, Bisogno G, Merks JHM. Ferrari A, et al. Lancet Child Adolesc Health. 2022 Aug;6(8):545-554. doi: 10.1016/S2352-4642(22)00121-3. Epub 2022 Jun 9. Lancet Child Adolesc Health. 2022. PMID: 35690071
Thiopurine Enhanced ALL Maintenance (TEAM): study protocol for a randomized study to evaluate the improvement in disease-free survival by adding very low dose 6-thioguanine to 6-mercaptopurine/methotrexate-based maintenance therapy in pediatric and adult patients (0-45 years) with newly diagnosed B-cell precursor or T-cell acute lymphoblastic leukemia treated according to the intermediate risk-high group of the ALLTogether1 protocol.
Toksvang LN, Als-Nielsen B, Bacon C, Bertasiute R, Duarte X, Escherich G, Helgadottir EA, Johannsdottir IR, Jónsson ÓG, Kozlowski P, Langenskjöld C, Lepik K, Niinimäki R, Overgaard UM, Punab M, Räty R, Segers H, van der Sluis I, Smith OP, Strullu M, Vaitkevičienė G, Wik HS, Heyman M, Schmiegelow K. Toksvang LN, et al. BMC Cancer. 2022 May 2;22(1):483. doi: 10.1186/s12885-022-09522-3. BMC Cancer. 2022. PMID: 35501736 Free PMC article.
Protocol for an Effectiveness-Implementation Hybrid Trial to Evaluate Scale up of an Evidence-Based Intervention Addressing Lifestyle Behaviours From the Start of Life: INFANT.
Laws R, Love P, Hesketh KD, Koorts H, Denney-Wilson E, Moodie M, Brown V, Ong KL, Browne J, Marshall S, Lioret S, Orellana L, Campbell KJ. Laws R, et al. Front Endocrinol (Lausanne). 2021 Nov 8;12:717468. doi: 10.3389/fendo.2021.717468. eCollection 2021. Front Endocrinol (Lausanne). 2021. PMID: 34975744 Free PMC article.
The evaluation of interventions at scale is a crucial, yet under-researched aspect of modifying population-level health behaviours. INFANT is an evidence-based early childhood healthy lifestyle intervention that aims to improve parents' knowledge and skills around promotin …
The evaluation of interventions at scale is a crucial, yet under-researched aspect of modifying population-level health behaviours. INFAN …
Protocol of controlled odorant stimulation for reducing apnoeic episodes in premature newborns: a randomised open-label Latin-square study with independent evaluation of the main endpoint (PREMODEUR).
Duchamp-Viret P, Nguyen HK, Maucort-Boulch D, Remontet L, Guyon A, Franco P, Cividjian A, Thevenet M, Iwaz J, Galletti S, Kassai B, Cornaton E, Plaisant F, Claris O, Gauthier-Moulinier H. Duchamp-Viret P, et al. BMJ Open. 2021 Sep 13;11(9):e047141. doi: 10.1136/bmjopen-2020-047141. BMJ Open. 2021. PMID: 34518252 Free PMC article.
METHODS AND ANALYSIS: The project is a randomised open-label Latin-square trial with independent evaluation of the main endpoint. It will include 60 preterm neonates from two university hospital neonatal intensive care units over 2 years (2021-2023). Each …
METHODS AND ANALYSIS: The project is a randomised open-label Latin-square trial with independent evaluation of the main endpoint. It will in …
A randomized EPIREMED protocol study on the long-term visuo spatial effects of very preterm children with a working memory deficit.
Gire C, Beltran Anzola A, Kaminski M, Baumstarck K, Ancel PY, Berbis J; for EPIREMED-Study Group. Gire C, et al. BMC Pediatr. 2021 Sep 13;21(1):402. doi: 10.1186/s12887-021-02867-x. BMC Pediatr. 2021. PMID: 34517869 Free PMC article.
BACKGROUND: Very preterm children generally perform poorly in executive functions and particularly in working memory. ...DISCUSSION: This project's primary goal is to demonstrate the necessity of early visuospatial memory assessment within the vulnerable population …
BACKGROUND: Very preterm children generally perform poorly in executive functions and particularly in working memory. ...DISCUSSION: …
Improving executive, behavioural and socio-emotional competences in very preterm young adolescents through a mindfulness-based intervention: Study protocol and feasibility.
Siffredi V, Liverani MC, Smith MM, Meskaldji DE, Stuckelberger-Grobéty F, Freitas LGA, De Albuquerque J, Savigny E, Gimbert F, Hüppi PS, Merglen A, Borradori Tolsa C, Leuchter RH. Siffredi V, et al. Early Hum Dev. 2021 Oct;161:105435. doi: 10.1016/j.earlhumdev.2021.105435. Epub 2021 Jul 31. Early Hum Dev. 2021. PMID: 34507019 Free article.
BACKGROUND: Very preterm (VPT) children and adolescents show executive, behavioural and socio-emotional difficulties that persist into adulthood. ...
BACKGROUND: Very preterm (VPT) children and adolescents show executive, behavioural and socio-emotional difficulties that persist int …
Tocolysis in the management of preterm prelabor rupture of membranes at 22-33 weeks of gestation: study protocol for a multicenter, double-blind, randomized controlled trial comparing nifedipine with placebo (TOCOPROM).
Lorthe E, Kayem G; TOCOPROM Study Group and the GROG (Groupe de Recherche en Obstétrique et Gynécologie). Lorthe E, et al. BMC Pregnancy Childbirth. 2021 Sep 8;21(1):614. doi: 10.1186/s12884-021-04047-2. BMC Pregnancy Childbirth. 2021. PMID: 34496799 Free PMC article.
BACKGROUND: Preterm prelabor rupture of membranes (PPROM) before 34 weeks of gestation complicates 1% of pregnancies and accounts for one-third of preterm births. ...Optimized prenatal management to improve the prognosis of infants born preterm could benefit …
BACKGROUND: Preterm prelabor rupture of membranes (PPROM) before 34 weeks of gestation complicates 1% of pregnancies and accounts for …
Determination of the optimal dose of ephedrine in the treatment of arterial hypotension due to general anesthesia in neonates and infants below 6 months old: the ephedrine study protocol for a randomized, open-label, controlled, dose escalation trial.
Szostek AS, Boucher P, Subtil F, Zerzaihi O, Saunier C, de Queiroz Siqueira M, Merquiol F, Martin P, Granier M, Gerst A, Lambert A, Storme T, Chassard D, Nony P, Kassai B, Gaillard S. Szostek AS, et al. Trials. 2021 Mar 12;22(1):208. doi: 10.1186/s13063-021-05155-2. Trials. 2021. PMID: 33712076 Free PMC article.
Intraoperative hypotension is observed with sevoflurane anesthesia in children, in particular in neonates, infants younger than 6 months, and preterm babies. Ephedrine is commonly used to treat intraoperative hypotension. ...The dose chosen as the reference is 0.1 m …
Intraoperative hypotension is observed with sevoflurane anesthesia in children, in particular in neonates, infants younger than 6 mon …
Rationale and design of ePPOP-ID: a multicenter randomized controlled trial using an electronic-personalized program for obesity in pregnancy to improve delivery.
Deruelle P, Lelorain S, Deghilage S, Couturier E, Guilbert E, Berveiller P, Sénat MV, Vayssière C, Sentilhes L, Perrotin F, Gallot D, Chauleur C, Sananes N, Roth E, Luton D, Caputo M, Lorio E, Chatelet C, Couster J, Timbely O, Doret-Dion M, Duhamel A, Pigeyre M. Deruelle P, et al. BMC Pregnancy Childbirth. 2020 Oct 7;20(1):602. doi: 10.1186/s12884-020-03288-x. BMC Pregnancy Childbirth. 2020. PMID: 33028261 Free PMC article.
Pregnancy is an ideal moment for nutritional interventions in order to establish healthier lifestyle behaviors in women at high risk of obstetric and neonatal complications. METHODS: Electronic-Personalized Program for Obesity during Pregnancy to Improve Delivery (ePPOP-ID …
Pregnancy is an ideal moment for nutritional interventions in order to establish healthier lifestyle behaviors in women at high risk of obst …