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187 results

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Quoted phrase not found in phrase index: "steoroids"
Page 1
Multi-omics and network pharmacology approaches reveal Gui-Ling-Ji alleviates oligoasthenoteratozoospermia by regulating arachidonic acid pathway.
Zhu R, Gao Z, Wu S, Ma S, Zhu Y, Zhang S, Zhang Y, Zeng H, Ma C, Zhao J, Ye J, Zhang W. Zhu R, et al. Phytomedicine. 2024 Dec;135:156184. doi: 10.1016/j.phymed.2024.156184. Epub 2024 Oct 28. Phytomedicine. 2024. PMID: 39488872
Testicular damage and weight loss caused by cyclophosphamide were restored in rats, the sperm count and motility were improved, and levels of luteinizing hormone (LH), follicle-stimulating hormone (FSH) and testosterone (T) secretion were also elevated …
Testicular damage and weight loss caused by cyclophosphamide were restored in rats, the sperm count and motility were improved, and l …
Integrative network pharmacology, transcriptomics, and proteomics reveal the material basis and mechanism of the Shen Qing Weichang Formula against gastric cancer.
Wang Y, Sun X, Ren M, Ma F, Zhao R, Zhu X, Xu Y, Cao N, Chen Y, Pan Y, Zhao A. Wang Y, et al. Chin Med. 2025 Mar 29;20(1):42. doi: 10.1186/s13020-025-01091-4. Chin Med. 2025. PMID: 40155922 Free PMC article.
BACKGROUND: Gastric cancer (GC) is a common malignancy with poor prognosis and lack of efficient therapeutic methods. ...Network pharmacology and molecular docking based on mass spectrometry showed that key targets (CASP3, TP53, Bcl-2, and AKT1) and core active components …
BACKGROUND: Gastric cancer (GC) is a common malignancy with poor prognosis and lack of efficient therapeutic methods. ...Network phar …
Glycyrrhiza glabra extract as a skin-whitening Agent: Identification of active components and CRTC1/MITF pathway-inhibition mechanism.
Liu J, Xu X, Jian M, Guo Y, Zhai L, Sun G, Sun L, Jiang R. Liu J, et al. J Ethnopharmacol. 2025 Jun 12;349:119948. doi: 10.1016/j.jep.2025.119948. Epub 2025 May 9. J Ethnopharmacol. 2025. PMID: 40350048
Seven major compounds were identified in GGE80: liquiritin, isoliquiritin, liquiritigenin, isoliquiritigenin, glycyrrhizic acid, 18beta-glycyrrhetinic acid, and glabridin. ...
Seven major compounds were identified in GGE80: liquiritin, isoliquiritin, liquiritigenin, isoliquiritigenin, glycyrrhizic acid, 18be …
Liquiritigenin Restores Declined Oocyte Quality and Improves Embryo Development in Aged Mice.
Cai Y, Ma J, Xu H, Jian H, Gao W, Wu M, Liu B, Chen Y. Cai Y, et al. Reprod Sci. 2025 Oct;32(10):3381-3392. doi: 10.1007/s43032-025-01959-8. Epub 2025 Aug 27. Reprod Sci. 2025. PMID: 40866779
Ovarian aging leads to a decline in oocyte quality and reduced reproductive potential, which is one of the main challenges faced by assisted reproductive technology (ART). ...In this study, we investigated the protective effects of natural flavonoid compound liqu …
Ovarian aging leads to a decline in oocyte quality and reduced reproductive potential, which is one of the main challenges faced by a …
Mechanistic study of Liquiritigenin inhibiting bladder cancer cell proliferation and migration by regulating STING1.
Li W, Yin Q, Qiu Y, Liu J, Wang J, Li C, Zhang D, Zhang P, Lv H, Lv Y, Wang Y. Li W, et al. Cancer Genet. 2025 Jun;294-295:156-170. doi: 10.1016/j.cancergen.2025.04.007. Epub 2025 Apr 27. Cancer Genet. 2025. PMID: 40347832
BACKGROUND: Bladder cancer (BLCA) is the most common malignant tumor in the urinary system, with a significantly higher incidence in men than in women, severely impacting quality of life. ...In vivo studies employed a mouse xenograft tumor model to systematic …
BACKGROUND: Bladder cancer (BLCA) is the most common malignant tumor in the urinary system, with a significantly higher incide …
Inhibition of AKR1Cs by liquiritigenin and the structural basis.
Liu H, Yao Z, Sun M, Zhang C, Huang YY, Luo HB, Wu D, Zheng X. Liu H, et al. Chem Biol Interact. 2023 Nov 1;385:110654. doi: 10.1016/j.cbi.2023.110654. Epub 2023 Sep 2. Chem Biol Interact. 2023. PMID: 37666442
In vivo and in vitro studies have confirmed that liquiritigenin (LQ), the primary active component of licorice, acts as an antitumor agent. However, how LQ diminishes or inhibits tumor growth is not fully understood. Here, we report the enzymatic inhibition of LQ an …
In vivo and in vitro studies have confirmed that liquiritigenin (LQ), the primary active component of licorice, acts as an antitumor …
Harnessing Liquiritigenin: A Flavonoid-Based Approach for the Prevention and Treatment of Cancer.
Sajeev A, Aswani BS, Alqahtani MS, Abbas M, Sethi G, Kunnumakkara AB. Sajeev A, et al. Cancers (Basel). 2025 Jul 13;17(14):2328. doi: 10.3390/cancers17142328. Cancers (Basel). 2025. PMID: 40723212 Free PMC article. Review.
CONCLUSIONS: LIQ represents a promising natural agent for cancer therapy, with evidence supporting its multifunctional role in targeting tumor growth and survival mechanisms. By providing a detailed analysis of LIQ, this review aims to highlight its therapeutic effi …
CONCLUSIONS: LIQ represents a promising natural agent for cancer therapy, with evidence supporting its multifunctional role in target …
A Review: The Pharmacology of Isoliquiritigenin.
Peng F, Du Q, Peng C, Wang N, Tang H, Xie X, Shen J, Chen J. Peng F, et al. Phytother Res. 2015 Jul;29(7):969-77. doi: 10.1002/ptr.5348. Epub 2015 Apr 24. Phytother Res. 2015. PMID: 25907962 Review.
Isoliquiritigenin (ISL) is one of the bioactive ingredients isolated from the roots of plants belonging to licorice, including Glycyrrhiza uralensis, Mongolian glycyrrhiza, Glycyrrhiza glabra, and so forth. Liquiritigenin is available in common foods and alternative medici …
Isoliquiritigenin (ISL) is one of the bioactive ingredients isolated from the roots of plants belonging to licorice, including Glycyrrhiza u …
Liquiritigenin inhibits the migration, invasion, and EMT of prostate cancer through activating ER stress.
Wang C, Liu B, Dan W, Wei Y, Li M, Guo C, Zhang Y, Xie H. Wang C, et al. Arch Biochem Biophys. 2024 Nov;761:110184. doi: 10.1016/j.abb.2024.110184. Epub 2024 Oct 22. Arch Biochem Biophys. 2024. PMID: 39447623 Free article.
Liquiritigenin (LQ) is a monomeric compound found in licorice, a leguminous plant, and has been reported to exhibit antitumor effects in various lines of cancer cells. ...In this study, the effects of LQ on the migration, invasion, and epithelial-mesenchymal transit …
Liquiritigenin (LQ) is a monomeric compound found in licorice, a leguminous plant, and has been reported to exhibit antitumor effects …
Liquiritigenin attenuates thrombosis by inhibiting P2Y(12)R-mediated Src/PLCgamma2 signaling and cytoplasmic Ca(2+) mobilization in platelets.
Cheng L, Yu T, Xue H, Xiang S. Cheng L, et al. Phytomedicine. 2025 Dec;149:157553. doi: 10.1016/j.phymed.2025.157553. Epub 2025 Nov 13. Phytomedicine. 2025. PMID: 41273866
Pathological thrombosis is a major underlying mechanism, where excessive platelet activation triggered by vascular injury constitutes a key event. Liquiritigenin, a key flavonoid constituent of Glycyrrhiza glabra l., has been reported to possess diverse pharmacological pro …
Pathological thrombosis is a major underlying mechanism, where excessive platelet activation triggered by vascular injury constitutes a key …
187 results