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Year Number of Results
1995 1
2005 1
2006 1
2007 2
2008 5
2009 5
2010 12
2011 18
2012 21
2013 32
2014 42
2015 46
2016 57
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2018 76
2019 104
2020 112
2021 140
2022 54
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665 results
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Maternal immune activation: Implications for neuropsychiatric disorders.
Estes ML, McAllister AK. Estes ML, et al. Science. 2016 Aug 19;353(6301):772-7. doi: 10.1126/science.aag3194. Science. 2016. PMID: 27540164 Free PMC article. Review.
Epidemiological evidence implicates maternal infection as a risk factor for autism spectrum disorder and schizophrenia. Animal models corroborate this link and demonstrate that maternal immune activation (MIA) alone is sufficient to impart lifelong neu …
Epidemiological evidence implicates maternal infection as a risk factor for autism spectrum disorder and schizophrenia. Animal models …
Maternal immune activation and neuroinflammation in human neurodevelopmental disorders.
Han VX, Patel S, Jones HF, Dale RC. Han VX, et al. Nat Rev Neurol. 2021 Sep;17(9):564-579. doi: 10.1038/s41582-021-00530-8. Epub 2021 Aug 2. Nat Rev Neurol. 2021. PMID: 34341569 Review.
The maternal immune activation hypothesis proposes that inflammatory perturbations in utero can affect fetal neurodevelopment, and evidence from human epidemiological studies supports an association between maternal inflammation during pregnancy and of …
The maternal immune activation hypothesis proposes that inflammatory perturbations in utero can affect fetal neurodevel …
Rescue of maternal immune activation-induced behavioral abnormalities in adult mouse offspring by pathogen-activated maternal Treg cells.
Xu Z, Zhang X, Chang H, Kong Y, Ni Y, Liu R, Zhang X, Hu Y, Yang Z, Hou M, Mao R, Liu WT, Du Y, Yu S, Wang Z, Ji M, Zhou Z. Xu Z, et al. Nat Neurosci. 2021 Jun;24(6):818-830. doi: 10.1038/s41593-021-00837-1. Epub 2021 Apr 15. Nat Neurosci. 2021. PMID: 33859437
Maternal immune activation (MIA) induced by lipopolysaccharides or polyinosinic:polycytidylic acid injections can induce behavioral abnormalities in adult mouse offspring. ...Single-cell RNA sequencing identified and characterized a unique group of pathogen-a …
Maternal immune activation (MIA) induced by lipopolysaccharides or polyinosinic:polycytidylic acid injections can induc …
Maternal immune activation and abnormal brain development across CNS disorders.
Knuesel I, Chicha L, Britschgi M, Schobel SA, Bodmer M, Hellings JA, Toovey S, Prinssen EP. Knuesel I, et al. Nat Rev Neurol. 2014 Nov;10(11):643-60. doi: 10.1038/nrneurol.2014.187. Epub 2014 Oct 14. Nat Rev Neurol. 2014. PMID: 25311587 Review.
Epidemiological studies have shown a clear association between maternal infection and schizophrenia or autism in the progeny. Animal models have revealed maternal immune activation (mIA) to be a profound risk factor for neurochemical and behavioural ab …
Epidemiological studies have shown a clear association between maternal infection and schizophrenia or autism in the progeny. Animal …
Brain changes in a maternal immune activation model of neurodevelopmental brain disorders.
Bergdolt L, Dunaevsky A. Bergdolt L, et al. Prog Neurobiol. 2019 Apr;175:1-19. doi: 10.1016/j.pneurobio.2018.12.002. Epub 2018 Dec 24. Prog Neurobiol. 2019. PMID: 30590095 Free PMC article. Review.
Here we review the behavior and brain phenotypes that have been characterized in MIA offspring, including the studies that have looked at the interaction between maternal immune activation and genetic risk factors for autism spectrum disorder or schizophrenia …
Here we review the behavior and brain phenotypes that have been characterized in MIA offspring, including the studies that have looked at th …
Maternal Immune Activation by Poly I:C as a preclinical Model for Neurodevelopmental Disorders: A focus on Autism and Schizophrenia.
Haddad FL, Patel SV, Schmid S. Haddad FL, et al. Neurosci Biobehav Rev. 2020 Jun;113:546-567. doi: 10.1016/j.neubiorev.2020.04.012. Epub 2020 Apr 19. Neurosci Biobehav Rev. 2020. PMID: 32320814 Review.
Maternal immune activation (MIA) in response to a viral infection during early and mid-gestation has been linked through various epidemiological studies to a higher risk for the child to develop autism or schizophrenia-related symptoms.. ...We here review and …
Maternal immune activation (MIA) in response to a viral infection during early and mid-gestation has been linked throug …
Maternal immune activation generates anxiety in offspring: A translational meta-analysis.
Quagliato LA, de Matos U, Nardi AE. Quagliato LA, et al. Transl Psychiatry. 2021 Apr 26;11(1):245. doi: 10.1038/s41398-021-01361-3. Transl Psychiatry. 2021. PMID: 33903587 Free PMC article. Review.
Maternal immune activation (MIA) during pregnancy is recognized as an etiological risk factor for various psychiatric disorders, such as schizophrenia, major depressive disorder, and autism. ...Overall, the meta-analysis showed that MIA induced anxiety behavi …
Maternal immune activation (MIA) during pregnancy is recognized as an etiological risk factor for various psychiatric d …
Maternal immune activation primes deficiencies in adult hippocampal neurogenesis.
Couch ACM, Berger T, Hanger B, Matuleviciute R, Srivastava DP, Thuret S, Vernon AC. Couch ACM, et al. Brain Behav Immun. 2021 Oct;97:410-422. doi: 10.1016/j.bbi.2021.07.021. Epub 2021 Aug 2. Brain Behav Immun. 2021. PMID: 34352366 Free PMC article. Review.
Decreased adult hippocampal neurogenesis (AHN) is a common feature across psychiatric disorders, including schizophrenia, depression- and anxiety-related behaviours, and is highly regulated by environmental influences. Epidemiological studies have consistently implicated mater …
Decreased adult hippocampal neurogenesis (AHN) is a common feature across psychiatric disorders, including schizophrenia, depression- and an …
Maternal Immune Activation and Schizophrenia-Evidence for an Immune Priming Disorder.
Choudhury Z, Lennox B. Choudhury Z, et al. Front Psychiatry. 2021 Feb 17;12:585742. doi: 10.3389/fpsyt.2021.585742. eCollection 2021. Front Psychiatry. 2021. PMID: 33679468 Free PMC article. Review.
The etiology of the disorder is due to many interacting genetic and environmental factors, with no one element causing the full spectrum of disease symptoms. Amongst these factors, maternal immune activation (MIA) acting during specific gestational timings ha …
The etiology of the disorder is due to many interacting genetic and environmental factors, with no one element causing the full spectrum of …
Beyond infection - Maternal immune activation by environmental factors, microglial development, and relevance for autism spectrum disorders.
Bilbo SD, Block CL, Bolton JL, Hanamsagar R, Tran PK. Bilbo SD, et al. Exp Neurol. 2018 Jan;299(Pt A):241-251. doi: 10.1016/j.expneurol.2017.07.002. Epub 2017 Jul 8. Exp Neurol. 2018. PMID: 28698032 Free PMC article. Review.
Immune molecules such as cytokines and chemokines and the cells that produce them within the brain, notably microglia, are critical for normal brain development. ...The heterogeneous clinical and biological phenotypes observed in ASD strongly suggest that in genetically su …
Immune molecules such as cytokines and chemokines and the cells that produce them within the brain, notably microglia, are critical f …
665 results