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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2003 1
2004 4
2005 3
2006 6
2007 3
2008 5
2009 2
2010 4
2011 2
2012 1
2013 8
2014 3
2015 2
2016 1
2017 1
2019 2
2020 1
2022 3
2023 1

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50 results

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Page 1
Gene silencing of SLC5A8 identified by genome-wide methylation profiling in lung cancer.
Park JY, Kim D, Yang M, Park HY, Lee SH, Rincon M, Kreahling J, Plass C, Smiraglia DJ, Tockman MS, Kim SJ. Park JY, et al. Lung Cancer. 2013 Mar;79(3):198-204. doi: 10.1016/j.lungcan.2012.11.019. Epub 2012 Dec 27. Lung Cancer. 2013. PMID: 23273563 Free PMC article.
Among 229 loci which were hypermethylated in lung tumors as compared to adjacent non-tumor tissues, solute carrier family 5, member 8 (SLC5A8) was one of the hypermethylated genes, and known as a tumor suppressor gene which is silenced by epigenetic changes i …
Among 229 loci which were hypermethylated in lung tumors as compared to adjacent non-tumor tissues, solute carrier family 5, member 8 (SL …
DNA hypermethylation and epigenetic silencing of the tumor suppressor gene, SLC5A8, in acute myeloid leukemia with the MLL partial tandem duplication.
Whitman SP, Hackanson B, Liyanarachchi S, Liu S, Rush LJ, Maharry K, Margeson D, Davuluri R, Wen J, Witte T, Yu L, Liu C, Bloomfield CD, Marcucci G, Plass C, Caligiuri MA. Whitman SP, et al. Blood. 2008 Sep 1;112(5):2013-6. doi: 10.1182/blood-2008-01-128595. Epub 2008 Jun 19. Blood. 2008. PMID: 18566324 Free PMC article.
Among the differentially methylated genes, the SLC5A8 tumor suppressor gene (TSG) was more frequently hypermethylated (P = .003). In MLL-PTD(+) cell lines having SLC5A8 promoter hypermethylation, incubation with decitabine activated SLC5A8 expre …
Among the differentially methylated genes, the SLC5A8 tumor suppressor gene (TSG) was more frequently hypermethylated ( …
Molecular mechanism of SLC5A8 inactivation in breast cancer.
Elangovan S, Pathania R, Ramachandran S, Ananth S, Padia RN, Srinivas SR, Babu E, Hawthorn L, Schoenlein PV, Boettger T, Smith SB, Prasad PD, Ganapathy V, Thangaraju M. Elangovan S, et al. Mol Cell Biol. 2013 Oct;33(19):3920-35. doi: 10.1128/MCB.01702-12. Epub 2013 Aug 5. Mol Cell Biol. 2013. PMID: 23918800 Free PMC article.
SLC5A8 is a putative tumor suppressor that is inactivated in more than 10 different types of cancer, but neither the oncogenic signaling responsible for SLC5A8 inactivation nor the functional relevance of SLC5A8 loss to tumor growth has been elucidated. ...Ma …
SLC5A8 is a putative tumor suppressor that is inactivated in more than 10 different types of cancer, but neither the oncogenic signal …
SLC5A8, a sodium transporter, is a tumor suppressor gene silenced by methylation in human colon aberrant crypt foci and cancers.
Li H, Myeroff L, Smiraglia D, Romero MF, Pretlow TP, Kasturi L, Lutterbaugh J, Rerko RM, Casey G, Issa JP, Willis J, Willson JK, Plass C, Markowitz SD. Li H, et al. Proc Natl Acad Sci U S A. 2003 Jul 8;100(14):8412-7. doi: 10.1073/pnas.1430846100. Epub 2003 Jun 26. Proc Natl Acad Sci U S A. 2003. PMID: 12829793 Free PMC article.
We identify a gene, SLC5A8, and show it is a candidate tumor suppressor gene whose silencing by aberrant methylation is a common and early event in human colon neoplasia. ...Structural homology and functional testing demonstrated that SLC5A8 is a membe …
We identify a gene, SLC5A8, and show it is a candidate tumor suppressor gene whose silencing by aberrant methylation is …
[The methylation and mRNA expression of SLC5A8 and TMS1/ASC genes in human glioma].
Jiang Z, Li XG, Hu J, Lu DR, Zhou W, Jiang YQ, Li CY. Jiang Z, et al. Zhonghua Yi Xue Za Zhi. 2007 Jan 30;87(5):292-7. Zhonghua Yi Xue Za Zhi. 2007. PMID: 17456354 Chinese.
OBJECTIVE: To study the methylation status of the SLC5A8 and TMS1/ASC genes, candidate tumor-inhibiting genes closely related to the central nervous system, in the promoter regions, the mRNA expression of these 2 genes, and their correlation with the c …
OBJECTIVE: To study the methylation status of the SLC5A8 and TMS1/ASC genes, candidate tumor-inhibiting genes closely r …
Protein expressions and genetic variations of SLC5A8 in prostate cancer risk and aggressiveness.
Lin HY, Park HY, Radlein S, Mahajan NP, Sellers TA, Zachariah B, Pow-Sang J, Coppola D, Ganapathy V, Park JY. Lin HY, et al. Urology. 2011 Oct;78(4):971.e1-9. doi: 10.1016/j.urology.2011.04.055. Epub 2011 Jul 29. Urology. 2011. PMID: 21802122 Free PMC article.
OBJECTIVE: To understand the role in prostate cancer risk and aggressiveness, we investigated the expression in prostate tumor and single nucleotide polymorphisms of SLC5A8. Previous studies have suggested that SLC5A8 might function as a tumor suppressor gene …
OBJECTIVE: To understand the role in prostate cancer risk and aggressiveness, we investigated the expression in prostate tumor and single nu …
Aberrant methylation and histone deacetylation associated with silencing of SLC5A8 in gastric cancer.
Ueno M, Toyota M, Akino K, Suzuki H, Kusano M, Satoh A, Mita H, Sasaki Y, Nojima M, Yanagihara K, Hinoda Y, Tokino T, Imai K. Ueno M, et al. Tumour Biol. 2004 May-Jun;25(3):134-40. doi: 10.1159/000079145. Tumour Biol. 2004. PMID: 15361710
Aberrant methylation of a sodium co-transporter, solute carrier family 5 member 8 gene (SLC5A8), has been detected in a subset of colorectal cancers, suggesting SLC5A8 may also serve as a tumor suppressor. ...In addition, chromatin immunoprecipitation assays …
Aberrant methylation of a sodium co-transporter, solute carrier family 5 member 8 gene (SLC5A8), has been detected in a subset …
Smartphone-Based Electrochemiluminescence for Visual Simultaneous Detection of RASSF1A and SLC5A8 Tumor Suppressor Gene Methylation in Thyroid Cancer Patient Plasma.
Khoshfetrat SM, Seyed Dorraji P, Shayan M, Khatami F, Omidfar K. Khoshfetrat SM, et al. Anal Chem. 2022 Jun 7;94(22):8005-8013. doi: 10.1021/acs.analchem.2c01132. Epub 2022 May 26. Anal Chem. 2022. PMID: 35616262
Through the design of a closed split bipolar electrochemistry system (BE), detection of promoter methylation of tumor suppressor genes in papillary thyroid cancer, RASSF1A and SLC5A8, was achieved using electrochemiluminescence. ...Moreover, taking advantages of the …
Through the design of a closed split bipolar electrochemistry system (BE), detection of promoter methylation of tumor suppressor genes …
Candidate tumor suppressor gene SLC5A8 is frequently down-regulated by promoter hypermethylation in prostate tumor.
Park JY, Zheng W, Kim D, Cheng JQ, Kumar N, Ahmad N, Pow-Sang J. Park JY, et al. Cancer Detect Prev. 2007;31(5):359-65. doi: 10.1016/j.cdp.2007.09.002. Epub 2007 Nov 26. Cancer Detect Prev. 2007. PMID: 18037591
RESULTS: The reduced or lost expression of SLC5A8 was observed in 70% of the tumor tissues. The bisulphite-modified sequencing analysis on the prostate cancer cell lines which do not express SLC5A8 detected the densely methylated SLC5A8 promoter region. ...CO …
RESULTS: The reduced or lost expression of SLC5A8 was observed in 70% of the tumor tissues. The bisulphite-modified sequencing analys …
Hypermethylated RASSF1 and SLC5A8 promoters alongside BRAFV600E mutation as biomarkers for papillary thyroid carcinoma.
Khatami F, Larijani B, Heshmat R, Nasiri S, Haddadi-Aghdam M, Teimoori-Toolabi L, Tavangar SM. Khatami F, et al. J Cell Physiol. 2020 Oct;235(10):6954-6968. doi: 10.1002/jcp.29591. Epub 2020 Feb 4. J Cell Physiol. 2020. PMID: 32017063
We aimed to study mutation in addition to the methylation status in the promoter regions of RASSF1 and SLC5A8 genes in tissues and circulating free DNA samples of patients affected with papillary thyroid carcinoma (PTC) and thyroid nodules as controls. ...On the oth …
We aimed to study mutation in addition to the methylation status in the promoter regions of RASSF1 and SLC5A8 genes in tissues …
50 results