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Year Number of Results
1965 1
1981 2
1982 1
1983 2
1984 2
1985 5
1987 3
1988 7
1989 2
1990 1
1992 8
1993 5
1994 3
1995 6
1996 2
1997 2
1998 6
1999 3
2000 2
2001 13
2002 6
2003 6
2004 10
2005 7
2006 10
2007 7
2008 15
2009 24
2010 20
2011 17
2012 18
2013 14
2014 16
2015 14
2016 12
2017 14
2018 13
2019 4
2020 0
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270 results
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Page 1
Capacity of octacalcium phosphate to promote osteoblastic differentiation toward osteocytes in vitro.
Sai Y, et al. Acta Biomater 2018. PMID 29378325
Octacalcium phosphate (OCP) has been shown to act as a nucleus for initial bone deposition and enhancing the early stages of osteoblastic differentiation. ...STATEMENT OF SIGNIFICANCE: Octacalcium phosphate (OCP) has been shown to have a superior osteoconductivity due to its capacity to enhance initial stage of osteoblast differentiation. ...
Octacalcium phosphate (OCP) has been shown to act as a nucleus for initial bone deposition and enhancing the early stages of o
Synthesis and enhanced bone regeneration of carbonate substituted octacalcium phosphate.
Shen D, et al. Biomed Mater Eng 2017. PMID 28269740
Using a wet method, we have synthesized octacalcium phosphate carbonate, in which HPO42- in octacalcium phosphate is replaced with CO32-. ...These results indicate that octacalcium phosphate carbonate has good biocompatibility and osteoconduction, and incorporation of carbonate into octacalcium phosphate and apatite enhances bone regeneration....
Using a wet method, we have synthesized octacalcium phosphate carbonate, in which HPO42- in octacalcium phosphate
First evidence of octacalcium phosphate@osteocalcin nanocomplex as skeletal bone component directing collagen triple-helix nanofibril mineralization.
Simon P, et al. Sci Rep 2018. PMID 30209287 Free PMC article.
Careful Fourier analysis reveals that the non-collagenous protein osteocalcin is present directly combined with octacalcium phosphate. ...In high-resolution TEM, the three binding sites of the γ-carboxylated glutamic acid groups of the mineralized osteocalcin were successfully imaged, which provide the chemical binding to octacalcium phosphate. ...
Careful Fourier analysis reveals that the non-collagenous protein osteocalcin is present directly combined with octacalcium phosph
Fabrication of octacalcium phosphate block through a dissolution-precipitation reaction using a calcium sulphate hemihydrate block as a precursor.
Sugiura Y, et al. J Mater Sci Mater Med 2018. PMID 30264167
Although octacalcium phosphate (OCP) powder and a collagen/gelatin composite demonstrate good potential as bone substitutes, an OCP block has not been fabricated to date. ...When the block was immersed in a phosphate salt solution, its composition changed to that of OCP, while its structure was maintained. ...
Although octacalcium phosphate (OCP) powder and a collagen/gelatin composite demonstrate good potential as bone substitutes, a …
Basic Mechanisms in Atherosclerosis: The Role of Calcium
Kalampogias A, et al. Med Chem 2016 - Review. PMID 26411606
The deposition of minerals in the form of calcium (Ca(2+)) initially emerges from the inorganing mineral octacalcium phosphate [Ca8H2(PO4)6.5H2O] to the form of Hydroxylapatite [Ca10(PO4)6(OH)2]. ...
The deposition of minerals in the form of calcium (Ca(2+)) initially emerges from the inorganing mineral octacalcium phosphate
Surface reactivity of octacalcium phosphate-derived fluoride-containing apatite in the presence of polyols and fluoride.
Tsutsui S, et al. J Biomed Mater Res B Appl Biomater 2018. PMID 29076293
The present study was designed to characterize co-precipitated fluoridated apatitic materials from octacalcium phosphate (OCP) precursor and to investigate their surface reactions with polyols including glycerol in the presence of fluoride ions. ...Glycerol enhanced the dissolution of phosphate from apatite crystals in particular from LS-FA. The results suggest that the apatite crystals, obtained through the hydrolysis of OCP in the presence of F, provide a more reactive surface than FA or HA under physiological environments. © 2017 Wiley Periodicals, Inc. ...
The present study was designed to characterize co-precipitated fluoridated apatitic materials from octacalcium phosphate (OCP) …
Osteogenic cellular activity around onlaid octacalcium phosphate-gelatin composite onto rat calvaria.
Iwama R, et al. J Biomed Mater Res A 2018. PMID 29316231
The activity and the distribution of osteogenic cells around octacalcium phosphate (OCP) granules combined with gelatin matrix (OCP/Gel) onlaid on rat calvaria were analyzed histomorphometrically and immunohistochemically during vertical bone augmentation under mechanical or nonmechanical environment until 8 weeks. ...
The activity and the distribution of osteogenic cells around octacalcium phosphate (OCP) granules combined with gelatin matrix …
Antiresorptive and anti-angiogenetic octacalcium phosphate functionalized with bisphosphonates: An in vitro tri-culture study.
Forte L, et al. Acta Biomater 2017. PMID 28238916
In this work, we synthesized octacalcium phosphate (OCP) in the presence of two potent BPs and obtained a single crystalline phase up to a zoledronate and alendronate content of 3.5wt% and 5.2wt%, respectively. ...In this study we functionalized octacalcium phosphate (OCP) with alendronate and zoledronate in order to get biomaterials able to couple the good biological performance of OCP with the therapeutic properties of the BPs. ...
In this work, we synthesized octacalcium phosphate (OCP) in the presence of two potent BPs and obtained a single crystalline p …
Bone regeneration by freeze-dried composite of octacalcium phosphate collagen and teriparatide.
Iwai A, et al. Oral Dis 2018. PMID 29943386
OBJECTIVE: Octacalcium phosphate (OCP) and collagen (col) composite (OCPcol) demonstrated superior bone regeneration properties, and its commercialization appears to be forthcoming. ...
OBJECTIVE: Octacalcium phosphate (OCP) and collagen (col) composite (OCPcol) demonstrated superior bone regeneration propertie …
Octacalcium phosphate: osteoconductivity and crystal chemistry.
Suzuki O. Acta Biomater 2010 - Review. PMID 20371385
Octacalcium phosphate (OCP), which is structurally similar to hydroxyapatite (HA), is a possible precursor of bone apatite crystals. ...Osteoconductivity and stimulatory capabilities may be caused by the chemical characteristics of OCP, which allows the release or exchange of calcium and phosphate ions with the surrounding of this salt, and its tendency to grow towards specific crystal faces, which could be a variable of the synthesis condition. ...
Octacalcium phosphate (OCP), which is structurally similar to hydroxyapatite (HA), is a possible precursor of bone apatite cry
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