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1949 1
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356 results

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Page 1
Cy5.5-8-Amino-octanoic acid-Ser-Cys-Pro-Pro-Trp-Gln-Glu-Trp-His-Asn-Phe-Met-Pro-Phe-NH(2).
Leung K. Leung K. 2012 Aug 21 [updated 2012 Nov 15]. In: Molecular Imaging and Contrast Agent Database (MICAD) [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2004–2013. 2012 Aug 21 [updated 2012 Nov 15]. In: Molecular Imaging and Contrast Agent Database (MICAD) [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2004–2013. PMID: 23166962 Free Books & Documents. Review.
Jeong et al. (18) identified one 12-mer peptide, Pro-Pro-Trp-Gln-Glu-Trp-His-Asn-Phe-Met-Pro-Phe-NH(2) (EGBP), with specific binding activity for human EGFR using phage display screening. The linker 8-mino-octanoic acid-Ser-Cys, (Aoc-SC) was added to the C-terminus …
Jeong et al. (18) identified one 12-mer peptide, Pro-Pro-Trp-Gln-Glu-Trp-His-Asn-Phe-Met-Pro-Phe-NH(2) (EGBP), with specific binding activit …
A metabolic shift to the serine pathway induced by lipids fosters epigenetic reprogramming in nontransformed breast cells.
Eduardo MB, Cottone G, McCloskey CW, Liu S, Palma FR, Zappia MP, Islam ABMMK, Gao P, Setya J, Dennis S, Gao H, Zhang Q, Xuei X, Luo Y, Locasale J, Bonini MG, Khokha R, Frolov MV, Benevolenskaya EV, Chandel NS, Khan SA, Clare SE. Eduardo MB, et al. Sci Adv. 2025 Mar 21;11(12):eads9182. doi: 10.1126/sciadv.ads9182. Epub 2025 Mar 21. Sci Adv. 2025. PMID: 40117373 Free PMC article.
We demonstrate that the metabolism of the paradigmatic medium-chain fatty acid octanoic acid leads to a metabolic shift toward the SOG and methionine pathways. ...These metabolic changes contribute to several hallmarks of cancer....
We demonstrate that the metabolism of the paradigmatic medium-chain fatty acid octanoic acid leads to a metabolic shift …
Caprylic (Octanoic) Acid as a Potential Fatty Acid Chemotherapeutic for Glioblastoma.
Altinoz MA, Ozpinar A, Seyfried TN. Altinoz MA, et al. Prostaglandins Leukot Essent Fatty Acids. 2020 Aug;159:102142. doi: 10.1016/j.plefa.2020.102142. Epub 2020 May 30. Prostaglandins Leukot Essent Fatty Acids. 2020. PMID: 32512365 Review.
Thus, a metabolic treatment based on therapeutic ketosis (reduced glucose with elevated ketone bodies) was proposed to treat GBM and was supoported from preclinical studies. Caprylic (octanoic) acid, a monocarboxylated saturated fatty acid, is among the best produce …
Thus, a metabolic treatment based on therapeutic ketosis (reduced glucose with elevated ketone bodies) was proposed to treat GBM and was sup …
Runners' metabolomic changes following marathon.
Shi R, Zhang J, Fang B, Tian X, Feng Y, Cheng Z, Fu Z, Zhang J, Wu J. Shi R, et al. Nutr Metab (Lond). 2020 Mar 13;17:19. doi: 10.1186/s12986-020-00436-0. eCollection 2020. Nutr Metab (Lond). 2020. PMID: 32190096 Free PMC article.

Lipid metabolism indexes, glycerol, glyceric acid, octanoic acid, and quinic acid increased significantly (p < 0.05). Theophylline, xanthine and other indicators of caffeine metabolism increased significantly (p < 0.05). Furthermore, marathon performanc

…

Lipid metabolism indexes, glycerol, glyceric acid, octanoic acid, and quinic acid increased significantly (p < 0.05)

…
Toxicity and toxicokinetics of perfluorooctanoic acid in humans and animals.
Kudo N, Kawashima Y. Kudo N, et al. J Toxicol Sci. 2003 May;28(2):49-57. doi: 10.2131/jts.28.49. J Toxicol Sci. 2003. PMID: 12820537 Free article. Review.
Perfluorooctanoic acid (PFOA) is an octanoic acid derivative to which all aliphatic hydrocarbons are substituted by fluorine. ...In rats, renal clearance of PFOA is regulated by sex hormones, especially testosterone. PFOA is excreted into urine by active tubu …
Perfluorooctanoic acid (PFOA) is an octanoic acid derivative to which all aliphatic hydrocarbons are substituted by fluorine. …
Octanoic acid mitigates busulfan-induced blood-testis barrier damage by alleviating oxidative stress and autophagy.
Cao C, Zhang H, He Z, Zhang K, Qian Z, Shen J, Zheng L, Xue M, Sun S, Li C, Zhao W, Jing J, Ma R, Ge X, Yao B. Cao C, et al. Lipids Health Dis. 2024 Jun 11;23(1):180. doi: 10.1186/s12944-024-02157-2. Lipids Health Dis. 2024. PMID: 38862993 Free PMC article.
BACKGROUND: The management of male infertility continues to encounter an array of challenges and constraints, necessitating an in-depth exploration of novel therapeutic targets to enhance its efficacy. As an eight-carbon medium-chain fatty acid, octanoic acid …
BACKGROUND: The management of male infertility continues to encounter an array of challenges and constraints, necessitating an in-depth expl …
Medium-Chain Fatty Acids and Breast Cancer Risk by Receptor and Pathological Subtypes.
Roopashree PG, Shetty SS, Shetty VV, Nalilu SK. Roopashree PG, et al. Nutrients. 2022 Dec 16;14(24):5351. doi: 10.3390/nu14245351. Nutrients. 2022. PMID: 36558514 Free PMC article.
We aimed to determine the medium-chain fatty acid levels in women with and without breast cancer. Materials and Methods: A total of 200 women (100 breast cancer subjects and 100 control subjects) were recruited for the study as per the inclusion and exclusion criter …
We aimed to determine the medium-chain fatty acid levels in women with and without breast cancer. Materials and Methods: A total of 2 …
Chemopreventive Effects of Alpha Lipoic Acid on Obesity-Related Cancers.
Moon HS. Moon HS. Ann Nutr Metab. 2016;68(2):137-44. doi: 10.1159/000443994. Epub 2016 Feb 2. Ann Nutr Metab. 2016. PMID: 26829711 Review.
BACKGROUND: It has been generally accepted that being overweight or obese is a risk factor for several types of cancers, including breast, thyroid, colon, pancreatic and liver. In fact, people who are obese have more fat tissues that can produce hormones, such as insulin o …
BACKGROUND: It has been generally accepted that being overweight or obese is a risk factor for several types of cancers, including breast, …
Decanoic Acid Stimulates Autophagy in D. discoideum.
Warren EC, Kramár P, Lloyd-Jones K, Williams RSB. Warren EC, et al. Cells. 2021 Oct 29;10(11):2946. doi: 10.3390/cells10112946. Cells. 2021. PMID: 34831171 Free PMC article.
We show that treatment with decanoic acid but not octanoic acid induces autophagosome formation and modulates autophagic flux in high glucose conditions. To investigate this effect, decanoic acid, but not octanoic acid, was found to induce the expressi …
We show that treatment with decanoic acid but not octanoic acid induces autophagosome formation and modulates autophagic flux …
Perfluoro-octanoic acid impairs sperm motility through the alteration of plasma membrane.
Šabović I, Cosci I, De Toni L, Ferramosca A, Stornaiuolo M, Di Nisio A, Dall'Acqua S, Garolla A, Foresta C. Šabović I, et al. J Endocrinol Invest. 2020 May;43(5):641-652. doi: 10.1007/s40618-019-01152-0. Epub 2019 Nov 27. J Endocrinol Invest. 2020. PMID: 31776969
We recently showed that accumulation of perfluoro-octanoic acid (PFOA) in human semen of exposed subjects was associated with altered motility parameters of sperm cells, suggesting direct toxicity. ...Sperm accumulation of PFOA was quantified by …
We recently showed that accumulation of perfluoro-octanoic acid (PFOA) in human semen of exposed subjects was associate …
356 results