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1975 2
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720 results

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Filters applied: Abstract, Review. Clear all
Quoted phrase not found in phrase index: "olfactory mucosal membrane"
Page 1
Olfaction.
Pinto JM. Pinto JM. Proc Am Thorac Soc. 2011 Mar;8(1):46-52. doi: 10.1513/pats.201005-035RN. Proc Am Thorac Soc. 2011. PMID: 21364221 Free PMC article. Review.
After signals are generated, olfactory information is processed and coded in the olfactory bulb and disseminated to several areas in the brain. ...Consequently, our knowledge of olfactory dysfunction in humans remains primitive. Aging represents the major cau …
After signals are generated, olfactory information is processed and coded in the olfactory bulb and disseminated to several ar …
Mammalian pheromones.
Liberles SD. Liberles SD. Annu Rev Physiol. 2014;76:151-75. doi: 10.1146/annurev-physiol-021113-170334. Epub 2013 Aug 26. Annu Rev Physiol. 2014. PMID: 23988175 Free PMC article. Review.
Here, I review several facets of pheromone transduction in mammals, including (a) chemosensory receptors and signaling components of the main olfactory epithelium and vomeronasal organ involved in pheromone detection; (b) pheromone-activated neural circuits subject to sex- …
Here, I review several facets of pheromone transduction in mammals, including (a) chemosensory receptors and signaling components of the mai …
The interleukin-4/interleukin-13 pathway in type 2 inflammation in chronic rhinosinusitis with nasal polyps.
Bachert C, Hicks A, Gane S, Peters AT, Gevaert P, Nash S, Horowitz JE, Sacks H, Jacob-Nara JA. Bachert C, et al. Front Immunol. 2024 Apr 16;15:1356298. doi: 10.3389/fimmu.2024.1356298. eCollection 2024. Front Immunol. 2024. PMID: 38690264 Free PMC article. Review.
Chronic rhinosinusitis with nasal polyps (CRSwNP) is predominantly a type 2 inflammatory disease associated with type 2 (T2) cell responses and epithelial barrier, mucociliary, and olfactory dysfunction. The inflammatory cytokines interleukin (IL)-4, IL-13, and IL-5 are ke …
Chronic rhinosinusitis with nasal polyps (CRSwNP) is predominantly a type 2 inflammatory disease associated with type 2 (T2) cell responses …
Olfactory receptor function.
Glezer I, Malnic B. Glezer I, et al. Handb Clin Neurol. 2019;164:67-78. doi: 10.1016/B978-0-444-63855-7.00005-8. Handb Clin Neurol. 2019. PMID: 31604564 Review.
Olfaction plays a critical role in several aspects of life. Olfactory disorders are very common in the general population, and can lead to malnutrition, weight loss, food poisoning, depression, and other disturbances. Odorants are first detected in the upper region of the …
Olfaction plays a critical role in several aspects of life. Olfactory disorders are very common in the general population, and can le …
Nose-to-Brain Delivery.
Wang Z, Xiong G, Tsang WC, Schätzlein AG, Uchegbu IF. Wang Z, et al. J Pharmacol Exp Ther. 2019 Sep;370(3):593-601. doi: 10.1124/jpet.119.258152. Epub 2019 May 24. J Pharmacol Exp Ther. 2019. PMID: 31126978 Free article. Review.
One way to bypass the blood brain barrier and thus treat diseases of the brain is to use the nasal route of administration and deposit drugs at the olfactory region of the nares, from where they travel to the brain via mechanisms that are still not clearly understood, with …
One way to bypass the blood brain barrier and thus treat diseases of the brain is to use the nasal route of administration and deposit drugs …
Reconstructing smell.
Barber RD, Ronnett GV. Barber RD, et al. Mol Neurobiol. 2000 Jun;21(3):161-73. doi: 10.1385/MN:21:3:161. Mol Neurobiol. 2000. PMID: 11379798 Review.
Odorant signal transduction and neurogenesis are fundamental properties of the olfactory epithelium. Many preparations have been used to elucidate some of the mechanisms underlying these properties. ...We focus specifically on the cell-culture paradigm and the data obtaine …
Odorant signal transduction and neurogenesis are fundamental properties of the olfactory epithelium. Many preparations have been used …
Olfactory receptors.
Gaillard I, Rouquier S, Giorgi D. Gaillard I, et al. Cell Mol Life Sci. 2004 Feb;61(4):456-69. doi: 10.1007/s00018-003-3273-7. Cell Mol Life Sci. 2004. PMID: 14999405 Free PMC article. Review.
The first step in odor transduction is mediated by binding odorants to olfactory receptors (ORs) which belong to the heptahelical G-protein-coupled receptor (GPCR) superfamily. ...In mammals, signal transduces through the G-protein-dependent signal pathway in the olfact …
The first step in odor transduction is mediated by binding odorants to olfactory receptors (ORs) which belong to the heptahelical G-p …
Mechanisms of SARS-CoV-2-associated anosmia.
Tsukahara T, Brann DH, Datta SR. Tsukahara T, et al. Physiol Rev. 2023 Oct 1;103(4):2759-2766. doi: 10.1152/physrev.00012.2023. Epub 2023 Jun 21. Physiol Rev. 2023. PMID: 37342077 Free PMC article. Review.
Anosmia, the loss of the sense of smell, is one of the main neurological manifestations of COVID-19. Although the SARS-CoV-2 virus targets the nasal olfactory epithelium, current evidence suggests that neuronal infection is extremely rare in both the olfactory …
Anosmia, the loss of the sense of smell, is one of the main neurological manifestations of COVID-19. Although the SARS-CoV-2 virus ta …
Olfactory receptor signaling.
Antunes G, Simoes de Souza FM. Antunes G, et al. Methods Cell Biol. 2016;132:127-45. doi: 10.1016/bs.mcb.2015.11.003. Epub 2015 Dec 24. Methods Cell Biol. 2016. PMID: 26928542 Review.
The guanine nucleotide protein (G protein)-coupled receptors (GPCRs) superfamily represents the largest class of membrane protein in the human genome. More than a half of all GPCRs are dedicated to interact with odorants and are termed odorant-receptors (ORs). ...In the la …
The guanine nucleotide protein (G protein)-coupled receptors (GPCRs) superfamily represents the largest class of membrane protein in …
How smell develops.
Mombaerts P. Mombaerts P. Nat Neurosci. 2001 Nov;4 Suppl:1192-8. doi: 10.1038/nn751. Nat Neurosci. 2001. PMID: 11687829 Review.
The mouse's sense of smell is built of approximately 1000 input channels. Each of these consists of a population of olfactory sensory neurons that express the same odorant receptor gene and project their axons to the same targets (glomeruli) in the olfactory …
The mouse's sense of smell is built of approximately 1000 input channels. Each of these consists of a population of olfactory …
720 results