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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1950 1
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1957 7
1958 6
1959 2
1960 6
1961 9
1962 3
1963 3
1964 6
1965 4
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1967 5
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1970 14
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1972 29
1973 40
1974 33
1975 25
1976 28
1977 36
1978 27
1979 21
1980 29
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1982 35
1983 44
1984 30
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1987 22
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1989 31
1990 33
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1992 40
1993 45
1994 51
1995 47
1996 50
1997 48
1998 41
1999 60
2000 60
2001 44
2002 52
2003 67
2004 62
2005 73
2006 89
2007 93
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2009 98
2010 99
2011 85
2012 105
2013 82
2014 92
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2016 99
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2,892 results

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Page 1
Mechanism Underlying Organophosphate Paraoxon-Induced Kinetic Tremor.
Iha HA, Kunisawa N, Shimizu S, Onishi M, Nomura Y, Matsubara N, Iwai C, Ogawa M, Hashimura M, Sato K, Kato M, Ohno Y. Iha HA, et al. Neurotox Res. 2019 Apr;35(3):575-583. doi: 10.1007/s12640-019-0007-7. Epub 2019 Feb 7. Neurotox Res. 2019. PMID: 30729450
Here, we performed behavioral and immunohistochemical studies in mice and rats to investigate the tremorgenic mechanism of paraoxon, an active metabolite of parathion. Treating animals with paraoxon (0.15-0.6 mg/kg, i.p.) elicited kinetic tremor in a dose-dependent …
Here, we performed behavioral and immunohistochemical studies in mice and rats to investigate the tremorgenic mechanism of paraoxon, …
Apoptosis is involved in paraoxon-induced histological changes in rat cerebellum.
Zare Z, Zarbakhsh S, Mashhadban S, Moradgholi A, Mohammadi M. Zare Z, et al. Drug Chem Toxicol. 2022 Nov;45(6):2554-2560. doi: 10.1080/01480545.2021.1966243. Epub 2021 Aug 19. Drug Chem Toxicol. 2022. PMID: 34412520
Adult male Wistar rats were intraperitoneally injected with paraoxon at 0.3, 0.7, or 1 mg/kg. Control animals were injected with corn oil as a vehicle. ...Findings showed the decreased thickness of both molecular and granular layers and reduction in the number of Purkinje …
Adult male Wistar rats were intraperitoneally injected with paraoxon at 0.3, 0.7, or 1 mg/kg. Control animals were injected with corn …
Enhancing Paraoxon Binding to Organophosphorus Hydrolase Active Site.
El Khoury L, Mobley DL, Ye D, Rempe SB. El Khoury L, et al. Int J Mol Sci. 2021 Nov 23;22(23):12624. doi: 10.3390/ijms222312624. Int J Mol Sci. 2021. PMID: 34884430 Free PMC article.
The best OPH substrate found to date is diethyl p-nitrophenyl phosphate (paraoxon). Most structural and kinetic studies assume that the binding orientation of paraoxon is identical to that of diethyl 4-methylbenzylphosphonate, which is the only substrate analog co-c …
The best OPH substrate found to date is diethyl p-nitrophenyl phosphate (paraoxon). Most structural and kinetic studies assume that t …
Enzymatic decontamination of paraoxon-ethyl limits long-term effects in planarians.
Poirier L, Plener L, Daudé D, Chabrière E. Poirier L, et al. Sci Rep. 2020 Mar 2;10(1):3843. doi: 10.1038/s41598-020-60846-1. Sci Rep. 2020. PMID: 32123261 Free PMC article.
We used Schmidtea mediterranea planarians to evaluate long-term effects of paraoxon-ethyl at two sublethal concentrations over three generations. Toxicity, developmental perturbations and disruption of behavior were rapidly observed and higher sensitivity to paraoxon …
We used Schmidtea mediterranea planarians to evaluate long-term effects of paraoxon-ethyl at two sublethal concentrations over three …
Combined Pre- and Posttreatment of Paraoxon Exposure.
Lorke DE, Nurulain SM, Hasan MY, Kuča K, Petroianu GA. Lorke DE, et al. Molecules. 2020 Mar 27;25(7):1521. doi: 10.3390/molecules25071521. Molecules. 2020. PMID: 32230733 Free PMC article.
Animals that received only pretreatment and paraoxon were compared with those that had received pretreatment and paraoxon followed by K-27 immediately after paraoxon exposure. RESULTS: Best protection from paraoxon-induced mortality was observed after …
Animals that received only pretreatment and paraoxon were compared with those that had received pretreatment and paraoxon foll …
Spectroscopic studies of methyl paraoxon decomposition over mesoporous Ce-doped titanias for toxic chemical filtration.
Leonard MB, Li T, Kramer MJ, McDonnell SM, Vedernikov AN, Rodriguez EE. Leonard MB, et al. J Hazard Mater. 2022 Sep 15;438:129536. doi: 10.1016/j.jhazmat.2022.129536. Epub 2022 Jul 6. J Hazard Mater. 2022. PMID: 35999722
We fully characterized TiO(2) and Ce-doped TiO(2) and found phase-pure oxides with cylindrical hexagonally packed pores and high surface areas (176-252 m(2)/g). Methyl paraoxon decomposition was tracked through UV/Vis and found Ce(0.15)Ti(0.85)O(2) to decompose the most me …
We fully characterized TiO(2) and Ce-doped TiO(2) and found phase-pure oxides with cylindrical hexagonally packed pores and high surface are …
Paraoxon-induced damage in rat hippocampus is associated with alterations in the expression of apoptosis-related proteins.
Zare Z, Zarbakhsh S, Tehrani M, Mohammadi M. Zare Z, et al. Pestic Biochem Physiol. 2020 Jun;166:104580. doi: 10.1016/j.pestbp.2020.104580. Epub 2020 Apr 8. Pestic Biochem Physiol. 2020. PMID: 32448426
To determine the possible role of apoptosis in the development of paraoxon-induced brain damage, we evaluated expression of apoptosis-related proteins, the extent of neuronal damage, and activation of astrocytes in rat hippocampus. ...Animals treated with 1 mg/kg of par …
To determine the possible role of apoptosis in the development of paraoxon-induced brain damage, we evaluated expression of apoptosis …
Dose-Dependency of Toxic Signs and Outcomes of Paraoxon Poisoning in Rats.
Maksimović ŽM, Škrbić R, Stojiljković MP. Maksimović ŽM, et al. Acta Medica (Hradec Kralove). 2022;65(1):8-17. doi: 10.14712/18059694.2022.10. Acta Medica (Hradec Kralove). 2022. PMID: 35793503 Free article.
The aim of the study was to analyse the clinical signs of acute paraoxon poisoning in rats and to determine the relationship between the intensity of signs of poisoning and the dose of paraoxon and/or the outcome of poisoning in rats. ...Fasciculations, seizures and …
The aim of the study was to analyse the clinical signs of acute paraoxon poisoning in rats and to determine the relationship between …
Paraoxon reversibly inhibits neurotoxic esterase.
Carrington CD, Abou-Donia MB. Carrington CD, et al. Toxicol Appl Pharmacol. 1985 Jun 15;79(1):175-8. doi: 10.1016/0041-008x(85)90380-1. Toxicol Appl Pharmacol. 1985. PMID: 4049405
It has recently been reported that two paraoxon-insensitive carboxylesterases may be distinguished by their sensitivity to mipafox. ...We have determined that this discrepancy is a result of differences in the technique of preinhibition by paraoxon and mipafox. We r …
It has recently been reported that two paraoxon-insensitive carboxylesterases may be distinguished by their sensitivity to mipafox. . …
Development of a yeast biosensor-biocatalyst for the detection and biodegradation of the organophosphate paraoxon.
Schofield DA, Westwater C, Barth JL, DiNovo AA. Schofield DA, et al. Appl Microbiol Biotechnol. 2007 Oct;76(6):1383-94. doi: 10.1007/s00253-007-1107-5. Epub 2007 Jul 31. Appl Microbiol Biotechnol. 2007. PMID: 17665192
Global transcription profiling was subsequently used to identify yeast genes, which were induced in the presence of paraoxon, and genes, which were associated with paraoxon hydrolysis. Paraoxon-inducible genes and genes associated with paraoxon hydroly …
Global transcription profiling was subsequently used to identify yeast genes, which were induced in the presence of paraoxon, and gen …
2,892 results