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974 results

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Quoted phrase not found in phrase index: "steoroids"
Page 1
Hypericin photoactivation induces triple-negative breast cancer cells pyroptosis by targeting the ROS/CALR/Caspase-3/GSDME pathway.
Liang C, Liu X, Yu J, Shi L, Wei W, Zhu Y, Feng M, Tang T, Li D, Yang T, Zheng J, Ma B, Wei L. Liang C, et al. J Adv Res. 2025 Nov;77:669-688. doi: 10.1016/j.jare.2025.01.042. Epub 2025 Jan 25. J Adv Res. 2025. PMID: 39870303 Free PMC article.
INTRODUCTION: Hypericin (HP), a natural photosensitizer, has demonstrated great efficacy in photodynamic therapy (PDT) for cancer treatment. In addition to the induction of apoptosis and necrosis through reactive oxygen species (ROS) generation, the therapeutic mechanisms …
INTRODUCTION: Hypericin (HP), a natural photosensitizer, has demonstrated great efficacy in photodynamic therapy (PDT) for cancer tre …
Hypericum Perforatum-Derived Exosomes-Like Nanovesicles: A Novel Natural Photosensitizer for Effective Tumor Photodynamic Therapy.
Ma X, Chen N, Zeng P, He Y, Zhang T, Lu Y, Li Z, Xu J, You J, Zheng Y, Wang L, Luo M, Wu J. Ma X, et al. Int J Nanomedicine. 2025 Feb 4;20:1529-1541. doi: 10.2147/IJN.S510339. eCollection 2025. Int J Nanomedicine. 2025. PMID: 39925681 Free PMC article.
In vivo, HPDEN-mediated PDT significantly suppressed tumor growth and induced extensive tumor necrosis, with no observable toxicity to major organs. ...
In vivo, HPDEN-mediated PDT significantly suppressed tumor growth and induced extensive tumor necrosis, with no observable tox …
Hypericin: chemical synthesis and biosynthesis.
Huang LF, Wang ZH, Chen SL. Huang LF, et al. Chin J Nat Med. 2014 Feb;12(2):81-8. doi: 10.1016/S1875-5364(14)60014-5. Chin J Nat Med. 2014. PMID: 24636057 Review.
Widespread attention to the antiviral and anti-tumor properties of hypericin has spurred investigations of the chemical synthesis and biosynthesis of this unique compound. ...
Widespread attention to the antiviral and anti-tumor properties of hypericin has spurred investigations of the chemical synthesis and …
Perylene diimide-based treatment and diagnosis of diseases.
Zhao Z, Xu N, Wang Y, Ling G, Zhang P. Zhao Z, et al. J Mater Chem B. 2021 Nov 10;9(43):8937-8950. doi: 10.1039/d1tb01752g. J Mater Chem B. 2021. PMID: 34657950 Review.
Furthermore, perylene diimide-based multifunctional nano-delivery systems are particularly emphasized, showing great therapeutic potential in the field of image-guided combination therapy in tumor therapy. Finally, the great opportunities and challenges still faced …
Furthermore, perylene diimide-based multifunctional nano-delivery systems are particularly emphasized, showing great therapeutic pote …
Hypericin in phototherapy.
Koren H, Schenk GM, Jindra RH, Alth G, Ebermann R, Kubin A, Koderhold G, Kreitner M. Koren H, et al. J Photochem Photobiol B. 1996 Nov;36(2):113-9. doi: 10.1016/s1011-1344(96)07357-5. J Photochem Photobiol B. 1996. PMID: 9002247
Our first experience with locally applied hypericin in a superficial tumor-plate was performed 8 weeks after the systemic administration of hematoporphyrin derivatives. For tumor light illumination we used an argon pumped dye laser tuned to 632 nm. Owing to satisfac …
Our first experience with locally applied hypericin in a superficial tumor-plate was performed 8 weeks after the systemic administrat …
Benzo[ghi]perylene.
[No authors listed] [No authors listed] IARC Monogr Eval Carcinog Risk Chem Hum. 1983 Dec;32:195-204. IARC Monogr Eval Carcinog Risk Chem Hum. 1983. PMID: 6586651 No abstract available.
Delivery of hypericin for photodynamic applications.
Saw CL, Olivo M, Soo KC, Heng PW. Saw CL, et al. Cancer Lett. 2006 Sep 8;241(1):23-30. doi: 10.1016/j.canlet.2005.10.020. Epub 2005 Nov 21. Cancer Lett. 2006. PMID: 16303248 Review.
Early cancer detection is critical in improving disease management outcomes. Cancer diagnosis presents unique difficulties mainly due to its pathological presentation and poor accessibility that could limit the usefulness of conventional white light endoscopy in ear …
Early cancer detection is critical in improving disease management outcomes. Cancer diagnosis presents unique difficulties mai …
Perylene.
[No authors listed] [No authors listed] IARC Monogr Eval Carcinog Risk Chem Hum. 1983 Dec;32:411-8. IARC Monogr Eval Carcinog Risk Chem Hum. 1983. PMID: 6586676 No abstract available.
Hypericin in cancer treatment: more light on the way.
Agostinis P, Vantieghem A, Merlevede W, de Witte PA. Agostinis P, et al. Int J Biochem Cell Biol. 2002 Mar;34(3):221-41. doi: 10.1016/s1357-2725(01)00126-1. Int J Biochem Cell Biol. 2002. PMID: 11849990 Review.
Photodynamic therapy (PDT) has been described as a promising new modality for the treatment of cancer. PDT involves the combination of a photosensitizing agent (photosensitizer), which is preferentially taken up and retained by tumor cells, and visible light of a wa …
Photodynamic therapy (PDT) has been described as a promising new modality for the treatment of cancer. PDT involves the combination o …
Molecular response to hypericin-induced photodamage.
Krammer B, Verwanger T. Krammer B, et al. Curr Med Chem. 2012;19(6):793-8. doi: 10.2174/092986712799034842. Curr Med Chem. 2012. PMID: 22214453 Review.
Hypericin (Hyp) is used as a powerful natural photosensitizer in photodynamic therapy (PDT). After selective accumulation in tumor tissue, vessels and matrix, and activated by visible light, it destroys the tumor mainly via generation of reactive oxygen species. ...
Hypericin (Hyp) is used as a powerful natural photosensitizer in photodynamic therapy (PDT). After selective accumulation in tumor ti …
974 results