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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1988 1
1989 2
1990 2
1991 1
1993 1
1997 2
1998 6
1999 6
2000 9
2001 19
2002 71
2003 193
2004 422
2005 642
2006 1027
2007 1402
2008 1688
2009 2012
2010 2491
2011 2858
2012 3137
2013 3374
2014 5019
2015 5649
2016 6049
2017 5984
2018 6179
2019 6409
2020 6934
2021 1558
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57,023 results
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Page 1
Systems Biology of Metabolism.
Nielsen J. Nielsen J. Annu Rev Biochem. 2017 Jun 20;86:245-275. doi: 10.1146/annurev-biochem-061516-044757. Epub 2017 Mar 8. Annu Rev Biochem. 2017. PMID: 28301739 Review.
Metabolism is highly complex and involves thousands of different connected reactions; it is therefore necessary to use mathematical models for holistic studies. The use of mathematical models in biology is referred to as systems biology. In this review, the p …
Metabolism is highly complex and involves thousands of different connected reactions; it is therefore necessary to use mathematical models f …
Systems biology primer: the basic methods and approaches.
Tavassoly I, Goldfarb J, Iyengar R. Tavassoly I, et al. Essays Biochem. 2018 Oct 26;62(4):487-500. doi: 10.1042/EBC20180003. Print 2018 Oct 26. Essays Biochem. 2018. PMID: 30287586 Review.
In recent years, the systems biology framework has enabled research in quantitative and systems pharmacology and precision medicine for complex diseases. Here, we present a brief overview of current experimental and computational methods used in systems
In recent years, the systems biology framework has enabled research in quantitative and systems pharmacology and precis …
Systems Biology in Aging Research.
Xia X, Han JJ. Xia X, et al. Adv Exp Med Biol. 2018;1086:1-15. doi: 10.1007/978-981-13-1117-8_1. Adv Exp Med Biol. 2018. PMID: 30232749 Review.
Systems biology is an approach to collect high-dimensional data and analyze in an integrated manner. As aging is a complicated physiological functional decline in biological system, the methods in systems biology could be utilized in aging studies. Her
Systems biology is an approach to collect high-dimensional data and analyze in an integrated manner. As aging is a complicated
Overview of Systems Biology and Omics Technologies.
Karahalil B. Karahalil B. Curr Med Chem. 2016;23(37):4221-4230. doi: 10.2174/0929867323666160926150617. Curr Med Chem. 2016. PMID: 27686657 Review.
Both qualitatively and quantitatively of biological system provide information about diseases, toxicities, therapies etc. Omics technologies, which systems biology brings, are valuable tools for comprehensive analyses. ...In the present review, it was aimed to give …
Both qualitatively and quantitatively of biological system provide information about diseases, toxicities, therapies etc. Omics technologies …
The Systems Biology of Single-Cell Aging.
Song R, Sarnoski EA, Acar M. Song R, et al. iScience. 2018 Sep 28;7:154-169. doi: 10.1016/j.isci.2018.08.023. Epub 2018 Sep 3. iScience. 2018. PMID: 30267677 Free PMC article. Review.
Aging is a leading cause of human morbidity and mortality, but efforts to slow or reverse its effects are hampered by an incomplete understanding of its multi-faceted origins. Systems biology, the use of quantitative and computational methods to understand complex b …
Aging is a leading cause of human morbidity and mortality, but efforts to slow or reverse its effects are hampered by an incomplete understa …
Systems Biology Approaches in Autophagy Research.
Bao J, Liu B, Wu C. Bao J, et al. Adv Exp Med Biol. 2020;1207:699-706. doi: 10.1007/978-981-15-4272-5_52. Adv Exp Med Biol. 2020. PMID: 32671787 Review.
In this chapter, we focus on the systems biology method for autophagy research and introduce essential research skills and procedures. ...Overall, systems biology promises to act as a powerful tool which both helps to clarify the profound mechanism and …
In this chapter, we focus on the systems biology method for autophagy research and introduce essential research skills and pro …
Systems Biology-Based Investigation of Host-Plasmodium Interactions.
Smith ML, Styczynski MP. Smith ML, et al. Trends Parasitol. 2018 Jul;34(7):617-632. doi: 10.1016/j.pt.2018.04.003. Epub 2018 May 18. Trends Parasitol. 2018. PMID: 29779985 Free PMC article. Review.
Here, we provide an overview of recent efforts using systems biology approaches to study host-Plasmodium interactions and the biological themes that have emerged from these efforts. We discuss some of the challenges in using systems biology for this go …
Here, we provide an overview of recent efforts using systems biology approaches to study host-Plasmodium interactions and the …
Systems Biology Approach in Hypertension Research.
Delles C, Husi H. Delles C, et al. Methods Mol Biol. 2017;1527:69-79. doi: 10.1007/978-1-4939-6625-7_6. Methods Mol Biol. 2017. PMID: 28116708 Review.
Systems biology is an approach to study all genes, gene transcripts, proteins, metabolites, and their interactions in specific cells, tissues, organs, or the whole organism. ...Unlike other methods in this book there is no clear-cut protocol to explain a systems
Systems biology is an approach to study all genes, gene transcripts, proteins, metabolites, and their interactions in specific
Sulphur systems biology-making sense of omics data.
Watanabe M, Hoefgen R. Watanabe M, et al. J Exp Bot. 2019 Aug 19;70(16):4155-4170. doi: 10.1093/jxb/erz260. J Exp Bot. 2019. PMID: 31404467 Free PMC article. Review.
Systems biology approaches have been applied over the last two decades to study plant sulphur metabolism. These 'sulphur-omics' approaches have been developed in parallel with the advancing field of systems biology, which is characterized by permanent
Systems biology approaches have been applied over the last two decades to study plant sulphur metabolism. These 'sulphur-omics
Systems Biology-Derived Discoveries of Intrinsic Clocks.
Millius A, Ueda HR. Millius A, et al. Front Neurol. 2017 Feb 6;8:25. doi: 10.3389/fneur.2017.00025. eCollection 2017. Front Neurol. 2017. PMID: 28220104 Free PMC article. Review.
A systems approach to studying biology uses a variety of mathematical, computational, and engineering tools to holistically understand and model properties of cells, tissues, and organisms. Building from early biochemical, genetic, and physiological studies, syst
A systems approach to studying biology uses a variety of mathematical, computational, and engineering tools to holistically un …
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