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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1948 1
1952 1
1965 1
1969 1
1972 1
1975 1
1976 1
1979 1
1983 2
1991 1
1995 1
1998 1
1999 2
2001 1
2002 1
2004 2
2005 1
2007 2
2008 1
2009 9
2010 12
2011 28
2012 64
2013 200
2014 322
2015 329
2016 371
2017 313
2018 255
2019 201
2020 190
2021 40
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2,114 results
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Page 1
Delivery technologies for genome editing.
Yin H, Kauffman KJ, Anderson DG. Yin H, et al. Nat Rev Drug Discov. 2017 Jun;16(6):387-399. doi: 10.1038/nrd.2016.280. Epub 2017 Mar 24. Nat Rev Drug Discov. 2017. PMID: 28337020 Review.
With the recent development of CRISPR technology, it is becoming increasingly easy to engineer the genome. Genome-editing systems based on CRISPR, as well as transcription activator-like effector nucleases (TALENs) and zinc-finger nucl …
With the recent development of CRISPR technology, it is becoming increasingly easy to engineer the genome. Genome-editing systems based on C …
Gene Editing With TALEN and CRISPR/Cas in Rice.
Bi H, Yang B. Bi H, et al. Prog Mol Biol Transl Sci. 2017;149:81-98. doi: 10.1016/bs.pmbts.2017.04.006. Epub 2017 May 24. Prog Mol Biol Transl Sci. 2017. PMID: 28712502 Review.
Engineered, site-specific nucleases induce genomic double-strand DNA breaks and break repair processes enable genome editing in a plethora of eukaryotic genomes. TALENs (transcription activator-like effector nucleases) and CRISPR/C …
Engineered, site-specific nucleases induce genomic double-strand DNA breaks and break repair processes enable genome editing in a ple …
Genome Editing with mRNA Encoding ZFN, TALEN, and Cas9.
Zhang HX, Zhang Y, Yin H. Zhang HX, et al. Mol Ther. 2019 Apr 10;27(4):735-746. doi: 10.1016/j.ymthe.2019.01.014. Epub 2019 Jan 25. Mol Ther. 2019. PMID: 30803822 Free PMC article. Review.
Genome-editing technologies based on programmable nucleases have significantly broadened our ability to make precise and direct changes in the genomic DNA of various species, including human cells. Delivery of programmable nucleases into the target tissue or cell is …
Genome-editing technologies based on programmable nucleases have significantly broadened our ability to make precise and direct chang …
CRISPR-Cas systems: ushering in the new genome editing era.
Perez Rojo F, Nyman RKM, Johnson AAT, Navarro MP, Ryan MH, Erskine W, Kaur P. Perez Rojo F, et al. Bioengineered. 2018;9(1):214-221. doi: 10.1080/21655979.2018.1470720. Bioengineered. 2018. PMID: 29968520 Free PMC article. Review.
Gene editing for cell engineering: trends and applications.
Gupta SK, Shukla P. Gupta SK, et al. Crit Rev Biotechnol. 2017 Aug;37(5):672-684. doi: 10.1080/07388551.2016.1214557. Epub 2016 Aug 18. Crit Rev Biotechnol. 2017. PMID: 27535623 Review.
Gene editing with all its own advantages in molecular biology applications has made easy manipulation of various production hosts with the discovery and implementation of modern gene editing tools such as Crispr (Clustered regularly interspaced short palindromic repeats), TALE …
Gene editing with all its own advantages in molecular biology applications has made easy manipulation of various production hosts with the d …
Mitochondrial Genome Engineering: The Revolution May Not Be CRISPR-Ized.
Gammage PA, Moraes CT, Minczuk M. Gammage PA, et al. Trends Genet. 2018 Feb;34(2):101-110. doi: 10.1016/j.tig.2017.11.001. Epub 2017 Nov 24. Trends Genet. 2018. PMID: 29179920 Free PMC article. Review.
Subsequently, attempts to manipulate mtDNA have been galvanized, although with few robust advances and much controversy. Re-engineered protein-only nucleases such as mtZFN and mitoTALEN function effectively in mammalian mitochondria, although efficient delivery of nucleic …
Subsequently, attempts to manipulate mtDNA have been galvanized, although with few robust advances and much controversy. Re-engineered prote …
A history of genome editing in mammals.
Fernández A, Josa S, Montoliu L. Fernández A, et al. Mamm Genome. 2017 Aug;28(7-8):237-246. doi: 10.1007/s00335-017-9699-2. Epub 2017 Jun 6. Mamm Genome. 2017. PMID: 28589393 Review.
This review summarizes the early development of genome editing using nucleases, from the pioneering experiments using yeast meganucleases, to the latest prokaryotic nucleases used for precise genome manipulation. Gene-editing nucleases belong to one of three …
This review summarizes the early development of genome editing using nucleases, from the pioneering experiments using yeast meganucle …
Genome Editing for the Understanding and Treatment of Inherited Cardiomyopathies.
Nguyen Q, Lim KRQ, Yokota T. Nguyen Q, et al. Int J Mol Sci. 2020 Jan 22;21(3):733. doi: 10.3390/ijms21030733. Int J Mol Sci. 2020. PMID: 31979133 Free PMC article. Review.
The global burden of cardiomyopathies is certainly high, necessitating further research and novel therapies. Genome editing tools, which include zinc finger nucleases (ZFNs), transcription activator-like effector nucleases (TALENs) …
The global burden of cardiomyopathies is certainly high, necessitating further research and novel therapies. Genome editing tools, which inc …
Genome-Editing Technologies: Concept, Pros, and Cons of Various Genome-Editing Techniques and Bioethical Concerns for Clinical Application.
Khan SH. Khan SH. Mol Ther Nucleic Acids. 2019 Jun 7;16:326-334. doi: 10.1016/j.omtn.2019.02.027. Epub 2019 Apr 3. Mol Ther Nucleic Acids. 2019. PMID: 30965277 Free PMC article. Review.
The techniques used to edit or change the genome evolved from the earlier attempts like nuclease technologies, homing endonucleases, and certain chemical methods. Molecular techniques like meganuclease, transcription activator-like effector …
The techniques used to edit or change the genome evolved from the earlier attempts like nuclease technologies, homing endonucleases, …
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