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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1998 1
1999 5
2000 8
2001 33
2002 56
2003 133
2004 193
2005 260
2006 322
2007 413
2008 445
2009 434
2010 526
2011 530
2012 601
2013 721
2014 700
2015 660
2016 614
2017 618
2018 678
2019 588
2020 641
2021 655
2022 569
2023 469
2024 449
2025 467
2026 7

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10,420 results

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Page 1
Integrative analysis identifies PIGK as an oncogenic glycosylphosphatidylinositol transamidase subunit with prognostic, immunological, and therapeutic relevance in head and neck cancer.
Yang YF, Liao JB, Yu PL, Chou CY, Lin YH. Yang YF, et al. Int J Med Sci. 2026 Jan 1;23(1):161-176. doi: 10.7150/ijms.121484. eCollection 2026. Int J Med Sci. 2026. PMID: 41399371
Clinical relevance is validated by immunohistochemistry on tissue microarray, and in vitro assays were conducted to assess PIGK-mediated phenotypes, regulation of Family with sequence similarity 20-member C (FAM20C), taxane response, and cancer-associated fibroblast …
Clinical relevance is validated by immunohistochemistry on tissue microarray, and in vitro assays were conducted to assess PIG …
DLX6 Drives Lung Adenocarcinoma Progression via the p27Kip1/CDK2-CCNE1 Signaling Pathway.
Sun Z, Ji F, Chen J, Song N, Liu M, Zhou M, Wang C, He S, Li M, Zhang Q, Ren B. Sun Z, et al. J Biochem Mol Toxicol. 2025 Dec;39(12):e70640. doi: 10.1002/jbt.70640. J Biochem Mol Toxicol. 2025. PMID: 41392461
Analysis of data from The Cancer Genome Atlas (TCGA) and Tissue Microarray (TMA) demonstrated that elevated DLX6 expression was associated with poor prognosis in LUAD patients. ...
Analysis of data from The Cancer Genome Atlas (TCGA) and Tissue Microarray (TMA) demonstrated that elevated DLX6 expression wa …
Single-Cell and Multiomic Analysis Reveals Neutrophil Heterogeneity and Prognostic Value in Cervical Lesions.
Wang Z, Zhuang L, Liu S, Cao C, Chen S, Yu N, Huang X, Zhang T. Wang Z, et al. Cancer Sci. 2025 Dec 12. doi: 10.1111/cas.70294. Online ahead of print. Cancer Sci. 2025. PMID: 41388279 Free article.
Analysis of 20 cervical biopsy samples across different disease stages identified five neutrophil subsets (N0-N4), among which the N4 subset exhibited a marked increase during disease advancement. Spatial transcriptomics and tissue microarray analyses revealed that …
Analysis of 20 cervical biopsy samples across different disease stages identified five neutrophil subsets (N0-N4), among which the N4 subset …
A new combined prognostic model involving SLC44A4 improves the predictive ability for colorectal cancer patients.
Li P, Cheng X, Wu Y, Fu G, Zhu J, Sheng C, Hu X, Jiang Z. Li P, et al. Transl Cancer Res. 2025 Nov 30;14(11):7725-7740. doi: 10.21037/tcr-2025-973. Epub 2025 Nov 26. Transl Cancer Res. 2025. PMID: 41378052 Free PMC article.
METHODS: To determine the prognostic significance of SLC44A4 in CRC, we evaluated this gene using online databases. Next, we used tissue-microarray-based immunohistochemistry (IHC) to assess the expression level of SLC44A4 protein in CRC tissues and analyzed the pro …
METHODS: To determine the prognostic significance of SLC44A4 in CRC, we evaluated this gene using online databases. Next, we used tissue
ZBTB7B modulates the androgen receptor as an upstream regulator via colocalization and direct binding in LNCaP prostate cancer cells.
Im E, Park SY, Sim DY, Cho AR, Kil BJ, Kim B, Shim BS, Kim SH. Im E, et al. Transl Cancer Res. 2025 Nov 30;14(11):7598-7610. doi: 10.21037/tcr-2025-1365. Epub 2025 Nov 26. Transl Cancer Res. 2025. PMID: 41378003 Free PMC article.
RNA interference was employed to deplete ZBTB7B or AR, and tissue expression patterns were analyzed by The Cancer Genome Atlas (TCGA) and human tissue microarray. RESULTS: ZBTB7B was overexpressed in prostate cancer cells and tissues with poor prognosis by human …
RNA interference was employed to deplete ZBTB7B or AR, and tissue expression patterns were analyzed by The Cancer Genome Atlas (TCGA) and hu …
Identification of Potential Biomarkers in Prostate Cancer Microarray Gene Expression Leveraging Explainable Machine Learning Classifiers.
Marouf AA, Rokne JG, Alhajj R. Marouf AA, et al. Cancers (Basel). 2025 Nov 30;17(23):3853. doi: 10.3390/cancers17233853. Cancers (Basel). 2025. PMID: 41375053 Free PMC article.
The k-fold stratified validation of machine learning (ML) models and SHAP values (SHapley Additive explanations) were used for explainability. Results: This study utilized a novel tissue microarray data set that has 102 patient data comprising prostate cancer and he …
The k-fold stratified validation of machine learning (ML) models and SHAP values (SHapley Additive explanations) were used for explainabilit …
Tissue Microarray-Based Digital Spatial Profiling of Benign Breast Lobules and Breast Cancers: Feasibility, Biological Coherence, and Cross-Platform Benchmarks.
Sherman ME, Carter JC, Vierkant RA, Stallings-Mann M, Pacheco-Spann L, Winham SJ, Vachon CM, Wang C, Jensen MR, Troester MA, Degnim AC, Thompson EA, Kachergus J, Shi J, Radisky DC. Sherman ME, et al. Cancers (Basel). 2025 Nov 27;17(23):3797. doi: 10.3390/cancers17233797. Cancers (Basel). 2025. PMID: 41374998 Free PMC article.
BACKGROUND: Discovering risk biomarkers in small benign breast disease (BBD) biopsies is constrained by scarce tissue and microanatomic heterogeneity of terminal duct lobular units (TDLUs). We tested whether tissue-sparing tissue microarray (TMA)-based Digital Spati …
BACKGROUND: Discovering risk biomarkers in small benign breast disease (BBD) biopsies is constrained by scarce tissue and microanatomic hete …
MicroRNA Profiling Identifies Diagnostic and Prognostic Markers in Pediatric Sarcoma.
Flatt TG, Yermakov LM, Akilesh S, Chen EY, Gonzalez E, Parrales A, Zapata-Tarres M, Cardenas-Cardos R, Velasco-Hidalgo L, Corcuera-Delgado C, Rodriguez-Jurado R, García-Rodríguez L, Farooqi MS, Ahmed AA. Flatt TG, et al. Cancers (Basel). 2025 Nov 27;17(23):3791. doi: 10.3390/cancers17233791. Cancers (Basel). 2025. PMID: 41374993 Free PMC article.
The expression of candidate miRNAs was validated with in situ hybridization (miRNA-ISH) and QuPath quantification on tissue microarray slides comprising an independent set of 48 OS, 17 EWS, and 104 RMS adult and pediatric cases collectively. ...
The expression of candidate miRNAs was validated with in situ hybridization (miRNA-ISH) and QuPath quantification on tissue microa
Circ_0001741 regulates proliferation and invasion in ESCC via the miR-194-5p/E2F3 axis.
Wang Y, Sun Q, Li Z. Wang Y, et al. World J Surg Oncol. 2025 Dec 10. doi: 10.1186/s12957-025-04124-2. Online ahead of print. World J Surg Oncol. 2025. PMID: 41372977 Free article.
Its expression was profiled using an ESCC tissue microarray. Functional effects of circ_0001741 on proliferation and invasion were assessed using CCK-8 and Transwell assays. ...
Its expression was profiled using an ESCC tissue microarray. Functional effects of circ_0001741 on proliferation and invasion …
Potentiation of ryanodine receptor-mediated calcium release by MAPK is responsible for epidermal transformation and carcinogenesis.
Wang P, Cleveland KH, Shahid A, Rathnayaka C, Amirrad F, Song Z, Estillore JP, Wang R, Back TG, Chen SRW, Huang Y. Wang P, et al. Proc Natl Acad Sci U S A. 2025 Dec 16;122(50):e2505055122. doi: 10.1073/pnas.2505055122. Epub 2025 Dec 10. Proc Natl Acad Sci U S A. 2025. PMID: 41370346
In vivo, UV-induced DNA damage and skin inflammation were enhanced by topical 4-CMC treatment but attenuated in the RyR2-E4872Q knock-in mice in which RyR2 activity is reduced. Human skin tissue microarray analysis confirmed spatial colocalization of phospho-ERK and …
In vivo, UV-induced DNA damage and skin inflammation were enhanced by topical 4-CMC treatment but attenuated in the RyR2-E4872Q knock-in mic …
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