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133 results

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Quoted phrase not found in phrase index: "steoroids"
Page 1
Maternal pregnancy levels of trans-nonachlor and oxychlordane and prevalence of cryptorchidism and hypospadias in boys.
Trabert B, Longnecker MP, Brock JW, Klebanoff MA, McGlynn KA. Trabert B, et al. Environ Health Perspect. 2012 Mar;120(3):478-82. doi: 10.1289/ehp.1103936. Epub 2011 Sep 7. Environ Health Perspect. 2012. PMID: 21975279 Free PMC article.
OBJECTIVE: To examine whether exposure to in utero chlordane is related to cryptorchidism and hypospadias, we evaluated levels of chlordane derivatives, trans-nonachlor and oxychlordane, among pregnant women enrolled in the Collaborative Perinatal Project (CPP). ... …
OBJECTIVE: To examine whether exposure to in utero chlordane is related to cryptorchidism and hypospadias, we evaluated levels of chlordane …
trans-Nonachlor and cis-nonachlor toxicity in Sprague-Dawley rats: comparison with technical chlordane.
Bondy GS, Newsome WH, Armstrong CL, Suzuki CA, Doucet J, Fernie S, Hierlihy SL, Feeley MM, Barker MG. Bondy GS, et al. Toxicol Sci. 2000 Dec;58(2):386-98. doi: 10.1093/toxsci/58.2.386. Toxicol Sci. 2000. PMID: 11099650
In this study, rats were administered cis-nonachlor, trans-nonachlor, or technical chlordane by gavage for 28 days at doses of 0.25 to 25 mg/kg body weight. ...Hepatic changes were most pronounced in rats treated with trans-nonachlor. Elevated k …
In this study, rats were administered cis-nonachlor, trans-nonachlor, or technical chlordane by gavage for 28 days at d …
"Trans-nonachlor increases extracellular free fatty acid accumulation and de novo lipogenesis to produce hepatic steatosis in McArdle-RH7777 cells".
Howell GE 3rd, McDevitt E, Henein L, Mulligan C, Young D. Howell GE 3rd, et al. Toxicol In Vitro. 2018 Aug;50:285-292. doi: 10.1016/j.tiv.2018.04.003. Epub 2018 Apr 11. Toxicol In Vitro. 2018. PMID: 29654899 Free PMC article.
Exposure to trans-nonachlor produced a concentration dependent increase in neutral lipid accumulation. ...Additionally, (14)C-acetate incorporation into total cellular lipids was increased by trans-nonachlor implicating increased de novo lipogenesis (D …
Exposure to trans-nonachlor produced a concentration dependent increase in neutral lipid accumulation. ...Additionally, (14)C- …
Alterations in macrophage phagocytosis and inflammatory tone following exposure to the organochlorine compounds oxychlordane and trans-nonachlor.
Young D, Worrell A, McDevitt E, Henein L, Howell GE 3rd. Young D, et al. Toxicol In Vitro. 2020 Jun;65:104791. doi: 10.1016/j.tiv.2020.104791. Epub 2020 Feb 10. Toxicol In Vitro. 2020. PMID: 32057836 Free PMC article.
Overall, exposure to oxychlordane significantly decreased macrophage phagocytosis while both OC compounds significantly increased ROS generation. Exposure to trans-nonachlor significantly increased secretion of tumor necrosis factor alpha (TNFalpha) and inter …
Overall, exposure to oxychlordane significantly decreased macrophage phagocytosis while both OC compounds significantly increased ROS genera …
Oxychlordane and trans-nonachlor in breast adipose tissue and risk of female breast cancer.
Zheng T, Holford TR, Tessari J, Mayne ST, Zahm SH, Owens PH, Zhang B, Ward B, Carter D, Zhang Y, Zhang W, Dubrow R, Boyle P. Zheng T, et al. J Epidemiol Biostat. 2000;5(3):153-60. J Epidemiol Biostat. 2000. PMID: 11051111
This paper examines the hypothesis that environmental exposure to trans-nonachlor (TNC) and oxychlordane (OCD), a major metabolite of the insecticide chlordane, increases the METHODS: A total of 304 histologically confirmed, incident primary breast-cancer pat …
This paper examines the hypothesis that environmental exposure to trans-nonachlor (TNC) and oxychlordane (OCD), a major metabo …
Organochlorine pesticides and prostate cancer, Is there an association? A meta-analysis of epidemiological evidence.
Lewis-Mikhael AM, Olmedo-Requena R, Martínez-Ruiz V, Bueno-Cavanillas A, Jiménez-Moleón JJ. Lewis-Mikhael AM, et al. Cancer Causes Control. 2015 Oct;26(10):1375-92. doi: 10.1007/s10552-015-0643-z. Epub 2015 Aug 6. Cancer Causes Control. 2015. PMID: 26245248 Review.
PURPOSE: The results of epidemiological studies about exposure to organochlorine pesticides (OCPs) and risk of prostate cancer (PC) are inconclusive. We conducted a meta-analysis to evaluate the association between exposure to specific OCPs and PC. ...Pooled estimates of P …
PURPOSE: The results of epidemiological studies about exposure to organochlorine pesticides (OCPs) and risk of prostate cancer (PC) a …
Plasma concentrations of persistent organic pollutants and pancreatic cancer risk.
Porta M, Gasull M, Pumarega J, Kiviranta H, Rantakokko P, Raaschou-Nielsen O, Bergdahl IA, Sandanger TM, Agudo A, Rylander C, Nøst TH, Donat-Vargas C, Aune D, Heath AK, Cirera L, Goñi-Irigoyen F, Alguacil J, Giménez-Robert À, Tjønneland A, Sund M, Overvad K, Mancini FR, Rebours V, Boutron-Ruault MC, Kaaks R, Schulze MB, Trichopoulou A, Palli D, Grioni S, Tumino R, Naccarati A, Panico S, Vermeulen R, Quirós JR, Rodríguez-Barranco M, Colorado-Yohar SM, Chirlaque MD, Ardanaz E, Wareham N, Key T, Johansson M, Murphy N, Ferrari P, Huybrechts I, Chajes V, Gonzalez CA, Bueno-de-Mesquita B, Gunter M, Weiderpass E, Riboli E, Duell EJ, Katzke V, Vineis P. Porta M, et al. Int J Epidemiol. 2022 May 9;51(2):479-490. doi: 10.1093/ije/dyab115. Int J Epidemiol. 2022. PMID: 34259837 Free PMC article.
RESULTS: Some associations were observed at higher concentrations of p, p'-DDT, trans-nonachlor, beta-hexachlorocyclohexane and the sum of six organochlorine pesticides and of 16 POPs. ...Among participants with a follow-up 10 years, estimates were higher than in p …
RESULTS: Some associations were observed at higher concentrations of p, p'-DDT, trans-nonachlor, beta-hexachlorocyclohexane an …
Organochlorine compounds and testicular dysgenesis syndrome: human data.
Cook MB, Trabert B, McGlynn KA. Cook MB, et al. Int J Androl. 2011 Aug;34(4 Pt 2):e68-84; discussion e84-5. doi: 10.1111/j.1365-2605.2011.01171.x. Epub 2011 Jun 13. Int J Androl. 2011. PMID: 21668838 Free PMC article. Review.
In this comprehensive review of human epidemiologic studies which have tested for associations between organochlorines and facets of TDS, we find evidence for associations between the exposures p,p'-DDE, cis-nonachlor and trans-nonachlor with testicular germ-cell tu …
In this comprehensive review of human epidemiologic studies which have tested for associations between organochlorines and facets of TDS, we …
Organochlorines and breast cancer risk: revisiting evidence through a meta-analytic approach.
Jena P, Pattnayak SP, Panda AK, Prusty BAK, Banerjee BD. Jena P, et al. Int J Environ Health Res. 2025 Dec 30:1-17. doi: 10.1080/09603123.2025.2609868. Online ahead of print. Int J Environ Health Res. 2025. PMID: 41467638 Review.
The risk of breast cancer in human subjects is associated with the exposure to organochlorines, although the findings have somewhat been inconclusive. ...Chlorinated compounds such as p,p' DDE (p = 0.000, SDM = 4.027: lipid-unadjusted; p = 0.001, SDM = 1.145: lipid adjuste …
The risk of breast cancer in human subjects is associated with the exposure to organochlorines, although the findings have somewhat b …
Body concentrations of persistent organic pollutants and prostate cancer: a meta-analysis.
Lim JE, Park SH, Jee SH, Park H. Lim JE, et al. Environ Sci Pollut Res Int. 2015 Aug;22(15):11275-84. doi: 10.1007/s11356-015-4315-z. Epub 2015 Mar 24. Environ Sci Pollut Res Int. 2015. PMID: 25797015
In dose-response meta-analysis, 1 mug/g lipid of PCBs was found to be associated with a 49% increased risk of prostate cancer (OR 1.49, 95% CI 1.07, 2.06). One nanogram per gram (1000 mug/g) lipid of trans-nonachlor was found to be associated with approximate …
In dose-response meta-analysis, 1 mug/g lipid of PCBs was found to be associated with a 49% increased risk of prostate cancer (OR 1.4 …
133 results