"vitamin D" "covid 19" - Search Results

Year	Number of Results
2020	376
2021	672
2022	548
2023	335
2024	233
2025	168
2026	11

1

Safety and Tolerability of Multimodal Therapy (Ivermectin, Doxycycline, Vitamin C, Vitamin D, and Zinc) With or Without Famotidine in Australian Patients With COVID-19 Infection: A Pilot Cohort Trial.

McLindon LA, Ried K, Wauchope B, Murnane L, Harradine E, Seman J. McLindon LA, et al. Am J Ther. 2026 Feb 16. doi: 10.1097/MJT.0000000000002118. Online ahead of print. Am J Ther. 2026. PMID: 41693032

STUDY QUESTION: To assess the safety and tolerability of a combination of repurposed drugs and supplements in the early therapy of acute nonhospitalized COVID-19 illness. STUDY DESIGN: A multicenter pilot cohort study was undertaken. Participants older than 40 years …

STUDY QUESTION: To assess the safety and tolerability of a combination of repurposed drugs and supplements in the early therapy of acute non …

2

Vitamin D in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome After COVID-19 or Vaccination: A Randomized Controlled Trial.

Kodama S, Nakata M, Konishi N, Yoshino M, Fujisawa A, Naganuma M, Kobayashi Y, Hirai Y, Kitagawa A, Miyokawa M, Mishima R, Teramukai S, Fukushima M. Kodama S, et al. Nutrients. 2026 Feb 3;18(3):521. doi: 10.3390/nu18030521. Nutrients. 2026. PMID: 41683343 Free PMC article. Clinical Trial.

In our prior retrospective study, most patients with PVS who developed ME/CFS had vitamin D insufficiency or deficiency. We evaluated the efficacy of vitamin D replacement therapy guidance for ME/CFS symptom improvement in patients with vitamin …

In our prior retrospective study, most patients with PVS who developed ME/CFS had vitamin D insufficiency or deficiency. We ev …

3

CRHR1 Gene Copy Number Variations, Chronic Viral Infections, and Age as Correlates of Cognitive Impairment in Adults After SARS-CoV-2 Infection.

Hovhannisyan Y, Yeritsyan H, Harutyunyan H, Azizian A, Yenkoyan K. Hovhannisyan Y, et al. Curr Issues Mol Biol. 2026 Jan 8;48(1):69. doi: 10.3390/cimb48010069. Curr Issues Mol Biol. 2026. PMID: 41614899 Free PMC article.

Analyses accounted for age and circulating levels of vitamins B12, B9, and vitamin D. CRHR1 CNVs affecting specific exons (Exon 1 [210 nucleotides] and Exon 11) were associated with objective cognitive impairment, whereas subjective cognitive complaints were more cl …

Analyses accounted for age and circulating levels of vitamins B12, B9, and vitamin D. CRHR1 CNVs affecting specific exons (Exo …

4

Dynamic Clinical and Laboratory Predictors of in-Hospital Mortality in COVID-19: A Multivariate Cox Regression Study.

Arabadzhiyska D, Deneva T, Stefanov R, Stoencheva S. Arabadzhiyska D, et al. Biomedicines. 2025 Dec 19;14(1):7. doi: 10.3390/biomedicines14010007. Biomedicines. 2025. PMID: 41595544 Free PMC article.

Background/Objectives: Identifying early and dynamic predictors of mortality in hospitalized COVID-19 patients is essential for improving prognosis and guiding therapy. Our aim is to evaluate clinical and laboratory predictors of in-hospital mortality among moderate …

Background/Objectives: Identifying early and dynamic predictors of mortality in hospitalized COVID-19 patients is essential fo …

5

Maternal-infant vitamin D coupling and neonatal hypocalcemia: a six-year cohort integrating preterm risk, onset timing, and pandemic effects.

Avşar H, Bülbül A, Baş EK, Uslu HS, Ünal ET, Divarcı A, Tellioğlu AY, Güzel B, Acar DB, Kazdal M. Avşar H, et al. BMC Pediatr. 2026 Jan 27. doi: 10.1186/s12887-026-06532-z. Online ahead of print. BMC Pediatr. 2026. PMID: 41593566 Free article. No abstract available.

6

The role of vitamin D for COVID-19.

Wang PH, Liu CH, Yang ST. Wang PH, et al. J Chin Med Assoc. 2026 Jan 21. doi: 10.1097/JCMA.0000000000001343. Online ahead of print. J Chin Med Assoc. 2026. PMID: 41559868 No abstract available.

7

Impact of a vitamin D supplementation initiative in an NHS prison health care service during the COVID-19 pandemic.

Dima A, McKinnon I, Whiting D, Tully J. Dima A, et al. Int J Prison Health (2024). 2026 Jan 19:1-10. doi: 10.1108/IJOPH-06-2025-0045. Online ahead of print. Int J Prison Health (2024). 2026. PMID: 41549738

Vitamin D was found to be protective against Covid-19 during the pandemic. As a response, Nottinghamshire Healthcare NHS Foundation Trust implemented a vitamin D supplementation policy across three prison health-care settings in the UK. . …

Vitamin D was found to be protective against Covid-19 during the pandemic. As a response, Nottinghamshire Health …

8

Evaluation of the Performance of New Fluorescence Immunoassay POCTs for Determining the Value of Vitamin D in Whole Blood.

Palermiti A, Manca A, Mastrantonio F, Maiese D, Cat Genova E, Menegatti G, Simiele M, Martino C, De Nicolò A, D'Avolio A. Palermiti A, et al. Molecules. 2025 Dec 30;31(1):130. doi: 10.3390/molecules31010130. Molecules. 2025. PMID: 41515426 Free PMC article.

Its deficiency is associated with various disorders, including chronic hypocalcemia and increased risk of severe diseases, such as COVID-19. Monitoring 25-hydroxyVD (25-OH-D) levels is vital, with serum 25-OH-VD being the standard marker. ...

Its deficiency is associated with various disorders, including chronic hypocalcemia and increased risk of severe diseases, such as COVID …

9

Role of Vitamin D Levels in COVID-19 Disease Severity: A Multicenter Retrospective Study from Qatar.

Jazar AS, Alalaween RB, Al-Saadi RK, Aljaffali NM, Al Arabi ZA, Ghabashi MA, Azzeh FS. Jazar AS, et al. Pak J Biol Sci. 2025 Dec;28(10):640-648. doi: 10.3923/pjbs.2025.640.648. Pak J Biol Sci. 2025. PMID: 41508942

Background and Objective: Up to now, evidence remains inconclusive about how vitamin D (VD) status relates to the severity of COVID-19 among hospitalized patients. ...Conclusion: Thi …

Background and Objective: Up to now, evidence remains inconclusive about how vitamin D (VD) …

10

Currently, no appropriately designed studies have demonstrated a link between vitamin-D levels and COVID-19 severity.

Daungsupawong H, Wiwanitkit V. Daungsupawong H, et al. J Chin Med Assoc. 2026 Feb 1;89(2):179. doi: 10.1097/JCMA.0000000000001335. Epub 2026 Jan 5. J Chin Med Assoc. 2026. PMID: 41486472 Free PMC article. No abstract available.

11

Characterization of COVID-19 patients in clinical, epidemiological, and laboratory settings: the role of vitamin D binding protein and vitamin D level in severity.

Al-Noori AS, Salih AM, Merza MA. Al-Noori AS, et al. Cell Mol Biol (Noisy-le-grand). 2025 Dec 28;71(12):39-48. doi: 10.14715/cmb/2025.71.12.6. Cell Mol Biol (Noisy-le-grand). 2025. PMID: 41456264

There are contradictory findings on the role of vitamin D-binding protein in COVID-19 development, disease severity, and outcomes. Therefore, we aimed to explore the association between the serum vitamin D level, DBP, and the COVID …

There are contradictory findings on the role of vitamin D-binding protein in COVID-19 development, disease sever …

12

Nutritional and inflammatory biomarkers for COVID-19 susceptibility: a focus on vitamin D, potassium, and hematological indices.

Khajebishak Y, Soleimani A, Madani S, Tanomand A, Ashrafi M, Badri Y, Norouz Yeganeh A, Payahoo L. Khajebishak Y, et al. BMC Infect Dis. 2025 Dec 23;26(1):164. doi: 10.1186/s12879-025-12297-0. BMC Infect Dis. 2025. PMID: 41436955 Free PMC article.

Creatinine levels were significantly lower in the COVID-19 group (p = 0.033). Additionally, the median vitamin D level was significantly lower in the COVID-19 group (33.0 ng/mL, IQR: 22.0-45.0; p < 0.001). A significant protective effe

…

Creatinine levels were significantly lower in the COVID-19 group (p = 0.033). Additionally, the median vitamin D …

13

Vitamin D levels in SARS-CoV-2: Do current adequacy thresholds reflect clinical risk? Insights from a large Turkish cohort.

Dandinoğlu T, Akselim S. Dandinoğlu T, et al. J Steroid Biochem Mol Biol. 2026 Mar;257:106925. doi: 10.1016/j.jsbmb.2025.106925. Epub 2025 Dec 16. J Steroid Biochem Mol Biol. 2026. PMID: 41412222

Clinical severity at admission, oxygen requirement, intensive care unit transfer, invasive ventilation, inflammatory markers, length of hospital stay, and in-hospital mortality were compared across vitamin D groups. No significant associations were observed between …

Clinical severity at admission, oxygen requirement, intensive care unit transfer, invasive ventilation, inflammatory markers, length of hosp …

14

Diagnostic Utility of Anti-Cyclic Citrullinated Peptide Antibodies Versus Rheumatoid Factor in Libyan Patients with Rheumatoid Arthritis: A Cross-Sectional Study.

Elmansorry E. Elmansorry E. Iran J Immunol. 2025 Dec 10;22(4):333-343. doi: 10.22034/iji.2025.108275.3090. Iran J Immunol. 2025. PMID: 41368929 Free article.

Statistical analyses were performed to evaluate associations between serological markers and clinical variables, including sex, age, family history, disease activity, comorbidities, smoking status, COVID-19 vaccination, and vitamin D levels. RESULTS: A …

Statistical analyses were performed to evaluate associations between serological markers and clinical variables, including sex, age, family …

15

Analysis of bibliometric and cross-cycle NHANES data: The effects of physical activity and vitamin D on pubertal onset in children aged 6-14 and the differences before and after the pandemic.

Liu B, Wu C, Qin J. Liu B, et al. Medicine (Baltimore). 2025 Dec 5;104(49):e46383. doi: 10.1097/MD.0000000000046383. Medicine (Baltimore). 2025. PMID: 41366930 Free PMC article.

This study included 3571 children and adolescents (6-14 years) from National Health and Nutrition Examination Survey cycles (2013-2016 and 2021-2023) with complete data on serum sex hormones, vitamin D levels, and PA measurements. Pubertal status was determined base …

This study included 3571 children and adolescents (6-14 years) from National Health and Nutrition Examination Survey cycles (2013-2016 and 2 …

16

Acute Kidney Injury Secondary to Vitamin D Intoxication: A Case of Oxalate Nephropathy.

Prime M, Segamwenge I, Mousa A. Prime M, et al. Cureus. 2025 Nov 7;17(11):e96305. doi: 10.7759/cureus.96305. eCollection 2025 Nov. Cureus. 2025. PMID: 41362524 Free PMC article.

Vitamin D excess and subsequent intoxication are an uncommon but recognised cause of acute kidney injury. ...It was later revealed by a family member that he had been taking large doses of vitamin D daily for more than three years, believing it would b …

Vitamin D excess and subsequent intoxication are an uncommon but recognised cause of acute kidney injury. ...It was later reve …

17

Vaccination and vitamin D in relation to disease severity and mortality in patients with COVID-19 disease: a follow-up study.

Al-Noori AS, Salih AM, Merza MA. Al-Noori AS, et al. Cell Mol Biol (Noisy-le-grand). 2025 Dec 6;71(11):100-108. doi: 10.14715/cmb/2025.71.11.13. Cell Mol Biol (Noisy-le-grand). 2025. PMID: 41351365

The objective of this study was to examine the effects of vitamin D and vaccination on mortality and disease severity in patients with COVID-16. ...Common symptoms were shortness of breath (66.67%), cough (75.68%), chest pain (60.81%), fatigue (52.7%), and anorexia …

The objective of this study was to examine the effects of vitamin D and vaccination on mortality and disease severity in patie …

18

Vitamin D in the elderly: the phil-rouge in preventing bone, muscle and adipose deterioration?

Filippo LD, Terenzi U, Giustina A. Filippo LD, et al. Arch Endocrinol Metab. 2025 Dec 3;70(Spe1):e250281. doi: 10.20945/2359-4292-2025-0281. Arch Endocrinol Metab. 2025. PMID: 41337665 Free PMC article. Review.

The pleiotropic role of vitamin D in human health has been implicated in modulating bone metabolism and other several extraskeletal areas, including muscle and adipose tissues regulation, and in influencing general and systemic outcomes. ...The pathophysiology of …

The pleiotropic role of vitamin D in human health has been implicated in modulating bone metabolism and other several extraske …

19

A Predictive Model for the Development of Long COVID in Children.

Perestiuk V, Sverstyuk A, Kosovska T, Volianska L, Boyarchuk O. Perestiuk V, et al. Int J Environ Res Public Health. 2025 Nov 9;22(11):1693. doi: 10.3390/ijerph22111693. Int J Environ Res Public Health. 2025. PMID: 41302639 Free PMC article.

The first model included basic demographic and clinical characteristics of the acute SARS-CoV-2 infection, as well as serum levels of vitamin D and zinc for all patients from both groups. The second model, in addition to the aforementioned parameters, also incorpora …

The first model included basic demographic and clinical characteristics of the acute SARS-CoV-2 infection, as well as serum levels of vit …

20

Exploring the Association of Vitamin D and VDR Polymorphisms with Disease Severity in COVID-19 and Influenza.

Sîrbu AC, Bocșan IC, Sabin O, Pop RM, Vesa ȘC, Feketea G, Briciu V, Lupșe M, Buzoianu AD. Sîrbu AC, et al. Biomedicines. 2025 Oct 25;13(11):2617. doi: 10.3390/biomedicines13112617. Biomedicines. 2025. PMID: 41301713 Free PMC article.

Vitamin D has been promoted as an immunomodulatory agent, with previous studies suggesting an association between vitamin D levels and disease severity in respiratory infections. Additionally, genetic variations in the vitamin D receptor …

Vitamin D has been promoted as an immunomodulatory agent, with previous studies suggesting an association between vitamin …

21

Serum vitamin D and inflammatory markers in SARS-CoV-2 positive pregnant women.

Mesarič VA, Premru Sršen T, Kavšek G, Verdenik I, Štrukelj A, Druškovič M. Mesarič VA, et al. J Perinat Med. 2025 Nov 26;54(1):183-188. doi: 10.1515/jpm-2025-0356. Print 2026 Jan 23. J Perinat Med. 2025. PMID: 41287148

RESULTS: Among 235 SARS-CoV-2-positive pregnant women 62.1 % had adequate and 21.3 % insufficient level of vitamin D and 13.6 % were vitamin D deficient. Statistical analysis revealed no significant correlations between 25-OH-vitamin D an …

RESULTS: Among 235 SARS-CoV-2-positive pregnant women 62.1 % had adequate and 21.3 % insufficient level of vitamin D and 13.6 …

22

Incidence and determinants of fracture risk in 8,348 Mongolian schoolchildren: secondary analysis of data from a randomised controlled trial.

Casson B, Jolliffe DA, Ariunbuyan S, Delgerekh B, Turmunkh T, Buyanjargal U, Martineau AR, Ganmaa D. Casson B, et al. medRxiv [Preprint]. 2025 Nov 2:2025.10.31.25339221. doi: 10.1101/2025.10.31.25339221. medRxiv. 2025. PMID: 41282877 Free PMC article. Preprint.

METHODS: We conducted secondary analyses of data from 8,348 schoolchildren aged 6-13 years living in Ulaanbaatar, Mongolia, who participated in a population-based randomised controlled trial of vitamin D supplementation with 3-year follow-up. Radial speed-of-sound ( …

METHODS: We conducted secondary analyses of data from 8,348 schoolchildren aged 6-13 years living in Ulaanbaatar, Mongolia, who participated …

23

There are currently no appropriately designed studies that demonstrate a link between vitamin-D levels and the COVID-19 severity.

Daungsupawong H, Wiwanitkit V. Daungsupawong H, et al. J Chin Med Assoc. 2025 Nov 24. doi: 10.1097/JCMA.0000000000001321. Online ahead of print. J Chin Med Assoc. 2025. PMID: 41276963 No abstract available.

24

Post-COVID-19-Associated Asymptomatic Sarcoidosis with Hypercalcemia and Renal Dysfunction: A Case Report and Literature Review.

Thiriveedi M, Patel H, Curran C, Patel S, Baddam S, ElBeblawy R, Reddy PJ. Thiriveedi M, et al. Am J Case Rep. 2025 Nov 1;26:e950045. doi: 10.12659/AJCR.950045. Am J Case Rep. 2025. PMID: 41175359 Free PMC article. Review.

The recent literature suggests that post-COVID-19 immune dysregulation may act as a novel trigger for sarcoidosis. CASE REPORT We present the case of a 60-year-old Black woman with hypertension, osteoarthritis, and a recent coronavirus disease 2019 (COVID- …

The recent literature suggests that post-COVID-19 immune dysregulation may act as a novel trigger for sarcoidosis. CASE REPORT …

25

RETRACTED: Argano et al. Protective Effect of Vitamin D Supplementation on COVID-19-Related Intensive Care Hospitalization and Mortality: Definitive Evidence from Meta-Analysis and Trial Sequential Analysis. Pharmaceuticals 2023, 16, 130.

Argano C, Bocchio RM, Natoli G, Scibetta S, Lo Monaco M, Corrao S. Argano C, et al. Pharmaceuticals (Basel). 2025 Oct 31;18(11):1645. doi: 10.3390/ph18111645. Pharmaceuticals (Basel). 2025. PMID: 41172117 Free PMC article.

The journal retracts the article "Protective Effect of Vitamin D Supplementation on COVID-19-Related Intensive Care Hospitalization and Mortality: Definitive Evidence from Meta-Analysis and Trial Sequential Analysis" [...]....

The journal retracts the article "Protective Effect of Vitamin D Supplementation on COVID-19-Related Intensive C …

26

Novel approach to substantiate cause-and-effect relationships: combining study ranking and statistical modelling, with a crucial role of data sharing.

Calame W, Slurink IAL, Budelli A; Working Group 1 of the Federation of European Nutrition Societies (FENS) Presidential Activity. Calame W, et al. Eur J Nutr. 2025 Oct 29;64(8):309. doi: 10.1007/s00394-025-03798-4. Eur J Nutr. 2025. PMID: 41160153

The ranking part concentrated around studies on the association between vitamin D status and severity (morbidity/mortality) of COVID-19 infection in hospitalized patients with criteria focussing on physiological and statistical relevance. ...

The ranking part concentrated around studies on the association between vitamin D status and severity (morbidity/mortality) of …

27

Role of the alpha-1 antitrypsin in the progression and severity of COVID-19 infection among Saudi patients.

Ali RA, Mohammedsaeed WA, Fakher MHA, Noor HK, Al Qurashi YM. Ali RA, et al. BMC Infect Dis. 2025 Oct 28;25(1):1422. doi: 10.1186/s12879-025-11699-4. BMC Infect Dis. 2025. PMID: 41152707 Free PMC article.

We aimed to screen frequencies of A1AT gene polymorphism among COVID-19 Saudi patients and its relation to severity. METHODS: Through cross-sectional study, we examined 100 COVID-19 Saudi patients to explore possible correlation between A1AT/interleuki …

We aimed to screen frequencies of A1AT gene polymorphism among COVID-19 Saudi patients and its relation to severity. METHODS: …

28

Evolving Features of Acute Flaccid Myelitis After COVID-19: A Four-Case Series.

Wang Q, Vedanarayanan V, Ho CY, Hardy D. Wang Q, et al. Pediatr Neurol. 2025 Dec;173:176-181. doi: 10.1016/j.pediatrneurol.2025.09.022. Epub 2025 Oct 7. Pediatr Neurol. 2025. PMID: 41138534

The biennial pattern of AFM outbreaks was disrupted by the COVID-19 pandemic, potentially altering the timing and clinical characteristics of AFM. ...Electrodiagnostic studies (in two cases) confirmed severe motor neuron injury. Low vitamin D levels we …

The biennial pattern of AFM outbreaks was disrupted by the COVID-19 pandemic, potentially altering the timing and clinical cha …

29

Vitamin D pathway as a multi-level predictor of COVID-19 severity and mortality: Integrating serum levels, FokI (rs2228570) VDR polymorphism, and lung tissue expression.

Awla HK, Othman BA, Rafeeq DD, Smail SW, Yashooa RK, Ghareeb AA, Salih RH, Omar SA, Janson C. Awla HK, et al. J Steroid Biochem Mol Biol. 2026 Jan;255:106879. doi: 10.1016/j.jsbmb.2025.106879. Epub 2025 Oct 22. J Steroid Biochem Mol Biol. 2026. PMID: 41135833 Free article.

BACKGROUND: Vitamin D is a known immunomodulator, but its predictive value in COVID-19 remains incompletely understood. This study investigates the role of vitamin D across molecular, biochemical, and histopathological levels to evaluate …

BACKGROUND: Vitamin D is a known immunomodulator, but its predictive value in COVID-19 remains incompletely unde …

30

Association between vitamin D polymorphisms and binding protein and COVID-19 risk and severity in children.

Giatraki V, Dimitriou H, Martimianaki G, Tsatsanis C, Galanakis E, Perdikogianni C. Giatraki V, et al. Clin Exp Pediatr. 2025 Dec;68(12):998-1006. doi: 10.3345/cep.2025.00577. Epub 2025 Oct 22. Clin Exp Pediatr. 2025. PMID: 41125221 Free PMC article.

BACKGROUND: The effects of genetic background on the biological effects of vitamin D on coronavirus disease 2019 (COVID-19) in children remain unclear. PURPOSE: This study aimed to explore the association between vitamin D-related genetic …

BACKGROUND: The effects of genetic background on the biological effects of vitamin D on coronavirus disease 2019 (COVID …

31

Vitamin D deficiency and respiratory health: A narrative review bridging gaps in public health through innovative strategies and sustainable solutions.

Li W, Chen X, Liu C, Olatunji OJ, Le TD, Ashaolu TJ, Ashaolu JO. Li W, et al. J Infect Public Health. 2026 Jan;19(1):103013. doi: 10.1016/j.jiph.2025.103013. Epub 2025 Oct 16. J Infect Public Health. 2026. PMID: 41110316 Free article. Review.

Vitamin D deficiency is a global public health issue, highly prevalent in middle-income and Eastern Mediterranean countries. It is associated with increased risks of respiratory infections like COVID-19 and influenza, alongside osteoporosis and cardiov …

Vitamin D deficiency is a global public health issue, highly prevalent in middle-income and Eastern Mediterranean countries. I …

32

Vitamin D may influence disease course in PIMS-TS/MIS-C: An observational cohort study.

Charlesworth JEG, Navarajasegaran J, Kavirayani A, Sarfatti A, Adwani S, Paulus S, Segal S, Gilchrist JJ, Kelly DF, Lees EA. Charlesworth JEG, et al. Pediatr Int. 2025 Jan-Dec;67(1):e70241. doi: 10.1111/ped.70241. Pediatr Int. 2025. PMID: 41099225 Free PMC article.

Furthermore, low serum vitamin D correlated with lower SARS-CoV-2 anti-nucleocapsid titers (spearman r = 0.43, p = 0.0014). ...CONCLUSIONS: Methylprednisolone suppressed CRP early and without evidence of coronary aneurysm in this cohort. We demonstrate a relationshi …

Furthermore, low serum vitamin D correlated with lower SARS-CoV-2 anti-nucleocapsid titers (spearman r = 0.43, p = 0.0014). .. …

33

Physiologically Based Pharmacokinetic Modelling of Serum 25-Hydroxyvitamin D Concentrations in Schoolchildren Receiving Weekly Oral Vitamin D(3) Supplementation.

Muhamad N, Walker N, Middelkoop K, Ganmaa D, Martineau AR, You T. Muhamad N, et al. Nutrients. 2025 Sep 23;17(19):3028. doi: 10.3390/nu17193028. Nutrients. 2025. PMID: 41097106 Free PMC article.

Background: Following vitamin D(3) oral administration, attained serum concentrations of its metabolite 25-hydroxyvitamin D(3) (25(OH)D(3)) are variable among children. ...Conclusion: We developed the first PBPK model to successfully predict the long-term serum 25(O …

Background: Following vitamin D(3) oral administration, attained serum concentrations of its metabolite 25-hydroxyvitamin D(3) …

34

Prevalence and risk factors for post-COVID-19 syndrome on medical students in Tabuk, Saudi Arabia-2023-2024.

Begum S, Mirghani HO, Alhowiti A, Alrasheed T, Sulaiman AHA. Begum S, et al. J Family Med Prim Care. 2025 Sep;14(9):3729-3734. doi: 10.4103/jfmpc.jfmpc_2017_24. Epub 2025 Sep 29. J Family Med Prim Care. 2025. PMID: 41089957 Free PMC article.

A web-based questionnaire detailing the demographic factors, post-COVID-19 symptoms, comorbidities, vitamin D deficiency, and the cumulative grade average (GPA) was used. ...Smoking was observed in 25%, and 58.5% were vitamin D deficient, …

A web-based questionnaire detailing the demographic factors, post-COVID-19 symptoms, comorbidities, vitamin D de …

35

Environmental risk factors of neuromyelitis optica spectrum disorder: a systematic review.

Mohammadi Lapevandani M, Bazmi E, Jahani S, Asgari N, Sahraian MA. Mohammadi Lapevandani M, et al. Ther Adv Neurol Disord. 2025 Oct 8;18:17562864251363293. doi: 10.1177/17562864251363293. eCollection 2025. Ther Adv Neurol Disord. 2025. PMID: 41080217 Free PMC article. Review.

A total of 21,410 NMOSD patients were included in the studies; 17,080 patients were females. Totally, 14 risk factors, including vitamin D deficiency, vaccination, virus infections, lifestyle, and dietary factors, were assessed. A total of 37% of the included articl …

A total of 21,410 NMOSD patients were included in the studies; 17,080 patients were females. Totally, 14 risk factors, including vitamin …

36

Linking COVID-19 and Cardiovascular Risk: The Diagnostic Potential of Asymmetric Dimethylarginine, Neopterin, and Vitamin D in Coronary Artery Disease.

Uncu G, Alp Avci G, Eren M, Avci E. Uncu G, et al. Cureus. 2025 Sep 8;17(9):e91814. doi: 10.7759/cureus.91814. eCollection 2025 Sep. Cureus. 2025. PMID: 41069894 Free PMC article.

MATERIALS AND METHODS: A total of 120 volunteers aged 30-65 years, presenting to a Chest Diseases Outpatient Clinic, were enrolled and categorized into four groups: COVID-19(+) vaccinated; COVID-19(+) unvaccinated; COVID-19(-) vaccinated; …

MATERIALS AND METHODS: A total of 120 volunteers aged 30-65 years, presenting to a Chest Diseases Outpatient Clinic, were enrolled and categ …

37

Vitamin D blood levels and vitamin D receptor polymorphisms contribute to post-acute sequelae of severe acute respiratory syndrome coronavirus 2 severity in the pediatric patients.

Chen PC, Hsu YL, Chen YH, Lin CY, Hsieh MH, Tsai HJ, Kuo WS, Kao HF, Wang SD, Ho YS, Cai CY, Shih-Hsin Wu L, Wang JY. Chen PC, et al. Clin Nutr ESPEN. 2025 Dec;70:303-308. doi: 10.1016/j.clnesp.2025.09.033. Epub 2025 Oct 9. Clin Nutr ESPEN. 2025. PMID: 41067382

BACKGROUND AND AIMS: Vitamin D, through the vitamin D receptor (VDR), modulates immune responses and may reduce inflammation linked to prolonged severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) symptoms. While vitamin D defici …

BACKGROUND AND AIMS: Vitamin D, through the vitamin D receptor (VDR), modulates immune responses and may reduce …

38

Vitamin D-inducible antimicrobial peptide LL-37 binds SARS-CoV-2 Spike and accessory proteins ORF7a and ORF8.

Roth A, Lütke S, Mörgelin M, Meinberger D, Hermes G, Sengle G, Koch M, Drexelius M, Gebauer J, Neundorf I, Elezagic D, Paulsson M, Streichert T, Klatt AR. Roth A, et al. Front Cell Infect Microbiol. 2025 Sep 23;15:1671738. doi: 10.3389/fcimb.2025.1671738. eCollection 2025. Front Cell Infect Microbiol. 2025. PMID: 41064641 Free PMC article.

BACKGROUND: The role of vitamin D in Coronavirus Disease 2019 (COVID-19) outcomes remains debated, but emerging evidence suggests it may enhance recovery by strengthening immune responses. Vitamin D upregulates LL-37, an antimicrobial pep …

BACKGROUND: The role of vitamin D in Coronavirus Disease 2019 (COVID-19) outcomes remains debated, but emerging …

39

Monitoring changes in vitamin D levels during the COVID-19 pandemic with routinely-collected laboratory data.

Skapetze L, Koller D, Zwergal A, Feuerriegel S, Rubinski A, Grill E. Skapetze L, et al. Nat Commun. 2025 Oct 2;16(1):8772. doi: 10.1038/s41467-025-64192-6. Nat Commun. 2025. PMID: 41038818 Free PMC article.

Vitamin D is critical for bone health and immune function, but the COVID-19 pandemic, characterized by lockdowns and reduced outdoor activity, raised concerns about potential declines in vitamin D levels due to dietary changes and limited …

Vitamin D is critical for bone health and immune function, but the COVID-19 pandemic, characterized by lockdowns …

40

Micronutrient status and fatty acid profile of adults with SARS-CoV-2 infection-an observational study.

Bleffgen M, Schinhammer L, De Rosa FG, Scabini S, Brandl B, Hauner H, Bo S, Skurk T. Bleffgen M, et al. Front Nutr. 2025 Sep 16;12:1608300. doi: 10.3389/fnut.2025.1608300. eCollection 2025. Front Nutr. 2025. PMID: 41036191 Free PMC article.

METHODS: This observational study compared micronutrient levels (vitamin D, selenium, zinc, magnesium, and iron) and lipid profiles between 139 SARS-CoV-2 -positive patients (62 hospitalized, 77 home care) and 314 healthy controls, using dried blood spots. ...

METHODS: This observational study compared micronutrient levels (vitamin D, selenium, zinc, magnesium, and iron) and lipid pro …

41

Comparison of Blood Parameters Between Omnivores and Lacto-Ovo Vegetarians Post-COVID-19: A Pilot Study Done in a Country City in the South of Brazil.

Santana Quinto B, Bertolassi MA, Março PH. Santana Quinto B, et al. J Med Food. 2025 Nov;28(11):1168-1174. doi: 10.1177/1096620X251377315. Epub 2025 Sep 29. J Med Food. 2025. PMID: 41020704

As obesity can, in many cases, be linked to lifestyle, dietary habits may influence physiological parameters, particularly in the period following viral infections such as COVID-19. This pilot study aimed to compare the blood parameters of individuals with different …

As obesity can, in many cases, be linked to lifestyle, dietary habits may influence physiological parameters, particularly in the period fol …

42

Association Between Vitamin D Levels and Long COVID Signs and Symptoms.

Matangkha K, Punyahotara V, Rintra J, Sittiprapaporn P. Matangkha K, et al. Med Sci (Basel). 2025 Sep 18;13(3):199. doi: 10.3390/medsci13030199. Med Sci (Basel). 2025. PMID: 40981197 Free PMC article.

OBJECTIVE: The study aimed to investigate the association between vitamin D levels and the prevalence of long COVID signs and symptoms in COVID-19 patients. ...IRR, 3.30 [2.12, 5.12]). CONCLUSION: Assessing and maintaining vitamin D level …

OBJECTIVE: The study aimed to investigate the association between vitamin D levels and the prevalence of long COVID signs and …

43

Vitamin D Status in Children: Romania's National Vitamin D Screening Programme in Context of the COVID-19 Pandemic.

Margan MM, Alexandru A, Ivan CS, Boeriu E, Tanasescu S, Cârstea AM, Varga NI, Margan R, Cindrea AC, Negrean RA. Margan MM, et al. Med Sci (Basel). 2025 Sep 16;13(3):193. doi: 10.3390/medsci13030193. Med Sci (Basel). 2025. PMID: 40981191 Free PMC article.

This study evaluates the effectiveness of Romania's National Vitamin D Screening Programme in detecting vitamin D deficiency in paediatric patients, while also accounting for the impact of the COVID-19 pandemic. ...CONCLUSIONS: The Nation …

This study evaluates the effectiveness of Romania's National Vitamin D Screening Programme in detecting vitamin D …

44

Comparative effectiveness of oral nutritional supplements in preventing respiratory tract infections among adults: a systematic review and network meta-analysis.

Zhu Z, Zhu X, Chu Y, Zhang B, Chen Y. Zhu Z, et al. EClinicalMedicine. 2025 Sep 2;88:103479. doi: 10.1016/j.eclinm.2025.103479. eCollection 2025 Oct. EClinicalMedicine. 2025. PMID: 40969681 Free PMC article.

Compared with placebo, catechin (RR = 0.79, 95% CI: 0.66, 0.95; n = 5; high certainty), Bifidobacterium animalis (RR = 0.79, 95% CI: 0.63, 0.99; n = 3; moderate certainty), and multi-strain probiotics (RR = 0.90, 95% CI: 0.82, 0.98; n = 16; moderate certainty) were the most effec …

Compared with placebo, catechin (RR = 0.79, 95% CI: 0.66, 0.95; n = 5; high certainty), Bifidobacterium animalis (RR = 0.79, 95% CI: 0.63, 0 …

45

Evaluation of Deficiency of Vitamin D and Advantages of Supplementation of Vitamin D in COVID-19 Infections: A Narrative Review.

Rastogi A, Sahoo JP, Sivasubramanian S, Mukhopadhyay S, Shukla R, Ramakrishnan S, Shaikh S, Abhyankar M, Prasad A, Kale S. Rastogi A, et al. J Assoc Physicians India. 2025 Sep;73(9):e38-e47. doi: 10.59556/japi.73.1169. J Assoc Physicians India. 2025. PMID: 40955938 Review.

The information was gathered from the PubMed database published between January 2020 and July 2022 regarding the function of vitamin D in the immune system, the link between deficiency of vitamin D and COVID-19 infection, severity, risk o …

The information was gathered from the PubMed database published between January 2020 and July 2022 regarding the function of vitamin …

46

Association of leukocyte telomere length and HbA1c with post-COVID-19 syndrome in type 2 diabetes: a cross-sectional pilot study.

Matviichuk A, Krasnienkov D, Yerokhovych V, Ilkiv Y, Korcheva V, Gurbych O, Shcherbakova A, Botsun P, Falalyeyeva T, Sulaieva O, Kobyliak N. Matviichuk A, et al. Front Med (Lausanne). 2025 Aug 29;12:1628156. doi: 10.3389/fmed.2025.1628156. eCollection 2025. Front Med (Lausanne). 2025. PMID: 40950970 Free PMC article.

MATERIALS AND METHODS: In this cross-sectional study, 66 T2D patients who had recovered from COVID-19 were enrolled. Patients were divided into two groups depending on PCS development: the PCS group (n = 44) and patients who did not develop PCS (n = 22) within 6 mon …

MATERIALS AND METHODS: In this cross-sectional study, 66 T2D patients who had recovered from COVID-19 were enrolled. Patients …

47

Vitamin D Status in a Large, Ethnically Diverse Patient Population Living in South East London at the Onset of the COVID-19 Pandemic: A Cross-Sectional Study Including a SARS-CoV-2 Positive Patient Subset.

Sobczyńska-Malefora A, Sulkowski A, Harbige L, Steed D, Harrington DJ. Sobczyńska-Malefora A, et al. Nutrients. 2025 Sep 4;17(17):2861. doi: 10.3390/nu17172861. Nutrients. 2025. PMID: 40944249 Free PMC article.

Background/Objectives: Vitamin D is involved in immune regulation, and deficiency may increase susceptibility to SARS-CoV-2 infection. ...Deficiency was most prevalent among Black patients. Vitamin D status should be monitored in patient populations, a …

Background/Objectives: Vitamin D is involved in immune regulation, and deficiency may increase susceptibility to SARS-CoV-2 in …

48

Association between vitamin D and COVID-19 infection and mortality in Taiwanese patients.

Sheng CC, Su SY, Liang Y, Cheng HC, Huang HY, Chiu HH. Sheng CC, et al. J Chin Med Assoc. 2025 Nov 1;88(11):887-893. doi: 10.1097/JCMA.0000000000001294. Epub 2025 Sep 12. J Chin Med Assoc. 2025. PMID: 40937665 Free PMC article.

BACKGROUND: Vitamin D plays a role in immune regulation and may influence coronavirus disease 2019 (COVID-19) outcomes. This study examined the association between serum vitamin D levels and COVID-19 infection and mortality …

BACKGROUND: Vitamin D plays a role in immune regulation and may influence coronavirus disease 2019 (COVID-19) ou …

49

Can correction of low vitamin D status in infancy program for a leaner body composition? A posttrial follow-up study of whole body lean mass in early childhood.

Razaghi M, Gharibeh N, Vanstone CA, Wei SQ, McNally D, Rauch F, Jones G, Heinonen K, Weiler HA. Razaghi M, et al. Am J Clin Nutr. 2025 Nov;122(5):1338-1350. doi: 10.1016/j.ajcnut.2025.09.002. Epub 2025 Sep 9. Am J Clin Nutr. 2025. PMID: 40935152 Free article. Clinical Trial.

BACKGROUND: Vitamin D supplementation is recommended for infants fed human milk and may have a role in supporting the development of lean body mass. OBJECTIVE: The main objective was to explore if the effects of 1000 IU/d compared with 400 IU/d of vitamin …

BACKGROUND: Vitamin D supplementation is recommended for infants fed human milk and may have a role in supporting the developm …

50

Perioperative Denosumab Versus Bisphosphonates for MIDLF Surgery in Patients With Osteopenia: A Short-Term Prospective Cohort Study.

Changsheng H, Yue L, Wang S, Sun H. Changsheng H, et al. Global Spine J. 2025 Sep 4;16(2):21925682251372500. doi: 10.1177/21925682251372500. Online ahead of print. Global Spine J. 2025. PMID: 40906581 Free PMC article.

Patients were divided into 3 groups: denosumab (60 mg subcutaneous injection), bisphosphonates (5 mg zoledronic acid intravenous infusion), and control (no anti-osteoporotic drugs, only calcium + vitamin D). Outcomes included fusion rates, clinical scores, bone meta …

Patients were divided into 3 groups: denosumab (60 mg subcutaneous injection), bisphosphonates (5 mg zoledronic acid intravenous infusion), …

51

Evaluation of vitamin D status, vitamin D receptor expression, and innate immune mediators in COVID-19.

Missilmani F, Maarabouni D, Salem-Sokhn E, Karras SN, Fakhoury HMA, El Shamieh S. Missilmani F, et al. Front Endocrinol (Lausanne). 2025 Aug 19;16:1600623. doi: 10.3389/fendo.2025.1600623. eCollection 2025. Front Endocrinol (Lausanne). 2025. PMID: 40904798 Free PMC article.

This study aimed to determine how serum vitamin D status and gene expression of VDR, DEFA1-3, and CCL20 associate with COVID-19 risk in a Lebanese cohort. ...RESULTS: Serum vitamin D levels and CCL20 expression were not significantly asso …

This study aimed to determine how serum vitamin D status and gene expression of VDR, DEFA1-3, and CCL20 associate with COVI …

52

Influence of Sex and 1,25α Dihydroxyvitamin D₃ on SARS-CoV-2 Infection and Viral Entry.

Vercellino N, Ferrari A, Sammartino JC, Bellan M, Iskandar E, Lilleri D, Minisini R. Vercellino N, et al. Pathogens. 2025 Aug 2;14(8):765. doi: 10.3390/pathogens14080765. Pathogens. 2025. PMID: 40872275 Free PMC article.

Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) is the etiologic agent that causes the coronavirus disease (COVID-19) identified in Wuhan, in 2019. Men are more prone to developing severe manifestations than women, suggesting a possible crucial role of …

Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) is the etiologic agent that causes the coronavirus disease (COVID-19 …

53

A Machine Learning Approach to Understanding the Genetic Role in COVID-19 Prognosis: The Influence of Gene Polymorphisms Related to Inflammation, Vitamin D, and ACE2.

Jaurrieta-Largo S, Miramontes-González JP, Corral-Gudino L, Gabella-Martín M, Pérez-Arroyo S, Torres AM, Mateo J, Pérez-Castrillón JL, Usategui-Martín R. Jaurrieta-Largo S, et al. Int J Mol Sci. 2025 Aug 18;26(16):7975. doi: 10.3390/ijms26167975. Int J Mol Sci. 2025. PMID: 40869297 Free PMC article.

The genetic background influences the outcomes of COVID-19. This study aimed to evaluate the incidence of polymorphisms in genes linked to the RAAS system, cytokine production, and vitamin D on COVID-19 severity, with the goal of gaining …

The genetic background influences the outcomes of COVID-19. This study aimed to evaluate the incidence of polymorphisms in gen …

54

Association between ionized calcium levels and 3-months mortality in geriatric patients hospitalized for COVID-19.

Boudaille A, Bourgeais A, Corvaisier M, Brière O, Gautier J, Annweiler C; GERIA-COVID study group. Boudaille A, et al. J Nutr Health Aging. 2025 Sep;29(9):100661. doi: 10.1016/j.jnha.2025.100661. Epub 2025 Aug 28. J Nutr Health Aging. 2025. PMID: 40882292 Free PMC article.

This specific unit specifically dedicated to COVID-19 patients was opened for 2 periods : from March 1, 2020 to June 30, 2020 and from October 1, 2020 to March 29, 2021. ...CONCLUSION: There is an association between CaI and 3 months mortality in geriatric patients …

This specific unit specifically dedicated to COVID-19 patients was opened for 2 periods : from March 1, 2020 to June 30, 2020 …

55

Prolonged Effects of COVID-19-Related Behavioral Restrictions on Neonatal Bone Metabolism: A Retrospective Study.

Goto T, Uemura A, Maeda H, Tanikawa M, Mizutani M, Kondo Y, Suyama M, Goto T, Maki K, Ushijima K. Goto T, et al. Cureus. 2025 Jul 23;17(7):e88618. doi: 10.7759/cureus.88618. eCollection 2025 Jul. Cureus. 2025. PMID: 40861548 Free PMC article.

Neonates were categorized into three groups: pre-COVID-19 (2018-2020), COVID-19 pandemic (2020-2022), and post-COVID-19 (2022-2024) periods. ...Magnesium levels significantly decreased in the post-COVID-19 period (pre-COV …

Neonates were categorized into three groups: pre-COVID-19 (2018-2020), COVID-19 pandemic (2020-2022), and post- …

56

Association Between the Vitamin D Receptor Polymorphism in rs7975232 with the COVID-19 Susceptibility.

Beiranvand Z, Alamdary A, Mohammadi R, Ajorloo M. Beiranvand Z, et al. Genet Test Mol Biomarkers. 2025 Aug;29(8):207-215. doi: 10.1177/19450265251366457. Epub 2025 Aug 14. Genet Test Mol Biomarkers. 2025. PMID: 40810656

Background: Vitamin D deficiency influences the pathogenicity and severity of coronavirus disease 2019 (COVID-19), suggesting that polymorphisms in the vitamin D receptor may impact disease susceptibility and outcomes. ...In CC genotype c …

Background: Vitamin D deficiency influences the pathogenicity and severity of coronavirus disease 2019 (COVID-19 …

57

Demographic and Clinical Profile of Patients with Osteogenesis Imperfecta Hospitalized Due to Coronavirus Disease (COVID)-19: A Case Series of 13 Patients from Brazil.

Morikawa LL, Marques LFA, Silva AEF, Costa PT, Mello LS, Fraga AMA, Marson FAL. Morikawa LL, et al. Healthcare (Basel). 2025 Jul 23;13(15):1779. doi: 10.3390/healthcare13151779. Healthcare (Basel). 2025. PMID: 40805812 Free PMC article.

Patients with a confirmed diagnosis of OI and hospitalization due to COVID-19 were included. Descriptive statistical analysis was performed to evaluate demographic, clinical, and outcome-related variables. We included all hospitalized COVID-19 cases wi …

Patients with a confirmed diagnosis of OI and hospitalization due to COVID-19 were included. Descriptive statistical analysis …

58

Sociodemographic factors, biomarkers and comorbidities associated with post-acute COVID-19 sequelae in UK Biobank.

Alcalde-Herraiz M, Iqbal S, Wallin JJ, Liu Y, Nieves W, Berry M, Catala M, Prieto-Alhambra D, Xie J. Alcalde-Herraiz M, et al. Nat Commun. 2025 Jul 30;16(1):7009. doi: 10.1038/s41467-025-62354-0. Nat Commun. 2025. PMID: 40738888 Free PMC article.

Long-term sequelae of COVID-19 remain critical public health concerns, with limited therapeutic options available. ...Additionally, obesity, socioeconomic deprivation, elevated C-reactive protein, triglyceride, vitamin D, HbA1c, cystatin C, urate, and …

Long-term sequelae of COVID-19 remain critical public health concerns, with limited therapeutic options available. ...Addition …

59

Self-medication and off-label prescribing in post COVID-19 syndrome: Baseline data of a randomized acupressure and qigong trial.

Bauer T, Grabowska W, Ortiz M, Bellmann-Strobl J, Engelhardt U, Nögel R, Hummelsberger J, Michalsen A, Roll S, Stöckigt B, Batram H, Mietzner A, Scheibenbogen C, Willich SN, Paul F, Brinkhaus B, Dietzel J. Bauer T, et al. Integr Med Res. 2025 Sep;14(3):101197. doi: 10.1016/j.imr.2025.101197. Epub 2025 Jul 5. Integr Med Res. 2025. PMID: 40727709 Free PMC article.

BACKGROUND: Post COVID-19 syndrome (PCS), characterized by persistent fatigue and multi-systemic symptoms following SARS-CoV-2 infection, emerged as a clinical challenge with limited treatment options and high patient burden. ...Patients frequently used off-label me …

BACKGROUND: Post COVID-19 syndrome (PCS), characterized by persistent fatigue and multi-systemic symptoms following SARS-CoV-2 …

60

Genetic Correlates of Presenile Dementia and Cognitive Decline in the Armenian Population Following COVID-19: A Case-Control Study.

Hovhannisyan Y, Yeritsyan H, Hakobjanyan G, Petrosyan G, Harutyunyan H, Muradyan A, Azizian A, Yenkoyan K. Hovhannisyan Y, et al. Int J Mol Sci. 2025 Jul 20;26(14):6965. doi: 10.3390/ijms26146965. Int J Mol Sci. 2025. PMID: 40725212 Free PMC article.

The presence of cognitive lapses in the post-COVID-19 period, particularly among younger individuals, suggests a potential genetic predisposition. ...The findings indicate that post-COVID-19 cognitive problems are multifactorial and are linked to genet …

The presence of cognitive lapses in the post-COVID-19 period, particularly among younger individuals, suggests a potential gen …

61

Early pandemic associations of latitude, sunshine duration, and vitamin D status with COVID-19 incidence and fatalities: A global analysis of 187 Countries.

Mogire RM. Mogire RM. PLOS Glob Public Health. 2025 Jul 28;5(7):e0004074. doi: 10.1371/journal.pgph.0004074. eCollection 2025. PLOS Glob Public Health. 2025. PMID: 40720505 Free PMC article.

This study explores how geographic latitude, sunshine duration, and vitamin D status were associated with the incidence and fatality rates of COVID-19 across 187 countries during the crucial early months of the outbreak. ...While the data highlight pot …

This study explores how geographic latitude, sunshine duration, and vitamin D status were associated with the incidence and fa …

62

Dietary intakes in relation to nutrition recommendations and dietary quality in an Iranian adult population: the results of the Food and Nutrition Surveillance (FNS).

Seifi N, Talkhi N, Khorasanchi Z, Soflaei SS, Sobhani SR, Abdollahi Z, Mottaghi Moghaddam Shahri A, Mohammadi-BajgIran M, A Ferns G, Esmaily H, Ghayour-Mobarhan M. Seifi N, et al. J Health Popul Nutr. 2025 Jul 26;44(1):268. doi: 10.1186/s41043-025-01022-x. J Health Popul Nutr. 2025. PMID: 40713780 Free PMC article.

The percentage of insufficiency was approximately 100% for retinol and vitamin D in both genders. Insufficient folate intake was 90.1% in women and 89.9% in men (p = 0.038). ...Carbohydrates, fat, and protein constituted 52.98%, 35.88%, and 13.9% of total energy int …

The percentage of insufficiency was approximately 100% for retinol and vitamin D in both genders. Insufficient folate intake w …

63

Dramatic Deterioration of Subclinical Hyperparathyroidism in Children and Adolescents During the Post-COVID-19 Period.

Loutsou M, Dermitzaki E, Paparodis RD, Michoula AN, Angelopoulos N, Christopoulos P, Diamantopoulos S, Mastorakos G, Grivea IN, Papadimitriou DT. Loutsou M, et al. Diseases. 2025 Jun 27;13(7):198. doi: 10.3390/diseases13070198. Diseases. 2025. PMID: 40709988 Free PMC article.

Background: Vitamin D is a steroid hormone, essential for the immune system and bone health. Since the sun is meant to provide at least 80% of daily vitamin D requirements, the COVID-19 pandemic is likely to have induced a considerable in …

Background: Vitamin D is a steroid hormone, essential for the immune system and bone health. Since the sun is meant to provide …

64

Efficacy and safety of narlumosbart, an anti-RANKL monoclonal antibody, in postmenopausal women with osteoporosis: a multi-center, randomized, double-blind, placebo- and active-controlled, phased II study.

Chi Y, Li Y, Cheng Q, Cai H, Zeng Y, Sheng H, Song B, Li H, Shen L, Li M, Xing Y, Cheng M, Ma Y, Wang D, Zhu M, Lu W, Yan S, Zhang X, Yuan J, Yang B, Li J, Wang J, Wu Z, Xia W. Chi Y, et al. EClinicalMedicine. 2025 Jul 4;85:103329. doi: 10.1016/j.eclinm.2025.103329. eCollection 2025 Jul. EClinicalMedicine. 2025. PMID: 40686685 Free PMC article.

Treatment-emergent adverse events (TEAEs) were observed in 91.9% of patients in the pooled narlumosbart groups, and 92.9% in both the placebo and the denosumab groups. Most common TEAEs were decreased vitamin D levels (34.1% [pooled narlumosbart] vs. 35.7% [placebo] …

Treatment-emergent adverse events (TEAEs) were observed in 91.9% of patients in the pooled narlumosbart groups, and 92.9% in both the placeb …

65

Effects of vitamin D on COVID-19 risk and hospitalisation in the UK biobank.

Monroy-Iglesias MJ, Thavarajah R, Beckmann K, Josephs DH, Irshad S, Karagiannis SN, Van Hemelrijck M, Santaolalla A. Monroy-Iglesias MJ, et al. PLoS One. 2025 Jul 18;20(7):e0328232. doi: 10.1371/journal.pone.0328232. eCollection 2025. PLoS One. 2025. PMID: 40679964 Free PMC article.

BACKGROUND: Vitamin D (VitD) plays an important role in immune modulation. VitD deficiency is associated with increased susceptibility to acute respiratory syndrome as observed in COVID-19. ...Binary multivariable logistic regression was performed to a …

BACKGROUND: Vitamin D (VitD) plays an important role in immune modulation. VitD deficiency is associated with increased suscep …

66

A scoping review: the impact of nutritional status on the efficacy, effectiveness, and immunogenicity of COVID-19 vaccines.

Oktaria V, Wiratama BS, Riyanto S, Purbaningrum RP, Kusuma CW, Saraswati LD, Widyaningsih V, Febrinasari RP, Probandari A, Ahmad RA. Oktaria V, et al. Trop Dis Travel Med Vaccines. 2025 Jul 15;11(1):21. doi: 10.1186/s40794-025-00258-z. Trop Dis Travel Med Vaccines. 2025. PMID: 40660410 Free PMC article. Review.

The most frequently studied vaccines were BNT162b2 (Pfizer, 74%), ChAdOx (AstraZeneca, 23%), and mRNA-1273 (Moderna, 14%). High BMI significantly reduced COVID-19 vaccine immunogenicity in 23 studies, while adequate vitamin D was associated with increa …

The most frequently studied vaccines were BNT162b2 (Pfizer, 74%), ChAdOx (AstraZeneca, 23%), and mRNA-1273 (Moderna, 14%). High BMI signific …

67

Telogen Effluvium Following Coronavirus Disease-2019 Infection: A Retrospective Study of 113 Cases.

Chhabra N, George CA, Ganguly S. Chhabra N, et al. Int J Trichology. 2025 Jan-Feb;17(1):32-35. doi: 10.4103/ijt.ijt_38_22. Epub 2025 Jun 23. Int J Trichology. 2025. PMID: 40654560 Free PMC article.

There is scarcity of data on TE as possible sequelae of COVID-19. METHODS: We assessed 113 cases of TE occurring after SARS-CoV-2 infection as a retrospective study. ...CONCLUSION: TE occurring after SARS-CoV-2 infection calls for assessment of micronutrient deficie …

There is scarcity of data on TE as possible sequelae of COVID-19. METHODS: We assessed 113 cases of TE occurring after SARS-Co …

68

Effect of COVID-19 Disease on Serum Vitamin D Status in Children with Asthma-A Retrospective Study.

Abdul-Razzak J, Ionescu M, Diaconu R, Popescu AD, Niculescu EC, Petrescu IO, Singer CE, Radu L, Anghelina L, Gheonea C. Abdul-Razzak J, et al. J Clin Med. 2025 Jun 26;14(13):4525. doi: 10.3390/jcm14134525. J Clin Med. 2025. PMID: 40648899 Free PMC article.

Similarly, children with acute respiratory infections/COVID-19 disease had lower median values of serum vitamin D, compared to children without acute respiratory infections/COVID-19 disease (p < 0.0005). A decrease in serum vitamin

…

Similarly, children with acute respiratory infections/COVID-19 disease had lower median values of serum vitamin D …

69

Reforming Food, Drug, and Nutraceutical Regulations to Improve Public Health and Reduce Healthcare Costs.

Wimalawansa SJ. Wimalawansa SJ. Foods. 2025 Jun 30;14(13):2328. doi: 10.3390/foods14132328. Foods. 2025. PMID: 40647079 Free PMC article. Review.

70

Skin cancer prevention in the Polish population during the COVID-19 pandemic.

Jęśkowiak-Kossakowska I, Calik J, Szeląg A, Wiatrak B. Jęśkowiak-Kossakowska I, et al. Front Public Health. 2025 Jun 20;13:1452043. doi: 10.3389/fpubh.2025.1452043. eCollection 2025. Front Public Health. 2025. PMID: 40620564 Free PMC article.

The aim of the study was to determine the occurrence of significant risk factors for skin cancer and to assess the methods of skin cancer prevention used in the Polish population during the COVID-19 pandemic. METHODS: An anonymous survey was conducted between Decemb …

The aim of the study was to determine the occurrence of significant risk factors for skin cancer and to assess the methods of skin cancer pr …

71

Vitamin D and COVID-19: How much more evidence do we need?

Kow CS, Hasan SS, Thiruchelvam K. Kow CS, et al. Nutr Clin Pract. 2025 Oct;40(5):1244-1245. doi: 10.1002/ncp.11349. Epub 2025 Jul 6. Nutr Clin Pract. 2025. PMID: 40618279 No abstract available.

72

Association between 25(OH)D levels and clinical outcomes in patients infected with SARS-CoV-2: a cross-sectional study.

Starosz A, Parfieniuk-Kowerda A, Martonik D, Moniuszko-Malinowska A, Pancewicz S, Flisiak R, Moniuszko M, Grubczak K. Starosz A, et al. Sci Rep. 2025 Jul 4;15(1):23986. doi: 10.1038/s41598-025-08621-y. Sci Rep. 2025. PMID: 40615533 Free PMC article.

Since the beginning, numerous research studies have been conducted to better understand the mechanisms contributing to the severe onset of SARS-CoV-2 infection. Immunomodulatory properties of vitamin D are known for their positive impact on multiple conditions. Neve …

Since the beginning, numerous research studies have been conducted to better understand the mechanisms contributing to the severe onset of S …

73

Association between vitamin D deficiency and clinical outcome in patients with COVID-19 in the post-Omicron phase.

Chen IW, Yu TS, Lai YC, Yang CP, Yu CH, Hung KC. Chen IW, et al. Front Nutr. 2025 Jun 18;12:1583276. doi: 10.3389/fnut.2025.1583276. eCollection 2025. Front Nutr. 2025. PMID: 40607018 Free PMC article.

BACKGROUND: Vitamin D deficiency (VDD) has been associated with adverse outcomes in COVID-19 patients during the early pandemic phases, but whether this association persists in the post-Omicron era remains uncertain. ...CONCLUSION: VDD continues to be …

BACKGROUND: Vitamin D deficiency (VDD) has been associated with adverse outcomes in COVID-19 patients during the …

74

Association Between Vitamin A and D Status and the Risk of COVID-19 in the Elderly Population: A Single-Center Experience.

Li T, Cui X, Li X, Yang J, Wang H, Yang J, Jin Z. Li T, et al. J Inflamm Res. 2025 Jun 24;18:8233-8241. doi: 10.2147/JIR.S522566. eCollection 2025. J Inflamm Res. 2025. PMID: 40585048 Free PMC article.

Vitamin A deficiency is a retinol below 30 ng/mL, and vitamin D deficiency is a 25(OH)D below 20 ng/mL. Multivariate logistic regression analysis was used to assess the relationship between vitamin A and D levels, nutritional status, and the risk of COVID- …

Vitamin A deficiency is a retinol below 30 ng/mL, and vitamin D deficiency is a 25(OH)D below 20 ng/mL. Multivariate logistic …

75

Effect of vitamin D supplementation on COVID-19 outcomes: an umbrella review of systematic reviews.

Petakh P, Kamyshna I, Halabitska I, Kamyshnyi O. Petakh P, et al. Front Nutr. 2025 Jun 13;12:1559471. doi: 10.3389/fnut.2025.1559471. eCollection 2025. Front Nutr. 2025. PMID: 40584095 Free PMC article.

BACKGROUND: Vitamin D is suggested as a supportive therapy to reduce the severity of COVID-19 due to its immunomodulatory and anti-inflammatory effects. ...CONCLUSION: While these findings suggest that vitamin D supplementation may help r …

BACKGROUND: Vitamin D is suggested as a supportive therapy to reduce the severity of COVID-19 due to its immunom …

76

ALBACOVIDIOL Study: Effect of Calcifediol Treatment on Mortality in Patients Hospitalized for COVID-19: A Retrospective Analysis.

Blázquez-Cabrera JA, Torres-Hernández J, Bouillon R, Casado-Díaz A, Quesada-Gomez JM, Navarro-Casado L. Blázquez-Cabrera JA, et al. Nutrients. 2025 Jun 10;17(12):1968. doi: 10.3390/nu17121968. Nutrients. 2025. PMID: 40573079 Free PMC article.

Background: Immunomodulatory treatments targeting excessive host immune responses favorably shifting the course of COVID-19. High doses of calcifediol may reduce the mortality of this infection. Objective: To evaluate how a high dose of calcifediol modifies the risk …

Background: Immunomodulatory treatments targeting excessive host immune responses favorably shifting the course of COVID-19. H …

77

Long COVID and Biomarker Dysregulation-A Shift Toward Immune Exhaustion?

Kallaste A, Kisand K, Aart A, Salumets A, Kisand K, Peterson P, Lember M. Kallaste A, et al. Medicina (Kaunas). 2025 May 28;61(6):996. doi: 10.3390/medicina61060996. Medicina (Kaunas). 2025. PMID: 40572685 Free PMC article.

Additionally, we analyzed differences between individuals with LC and those who recovered from COVID-19. Predictive models for LC at three months and sixth months post-infection were developed using inflammatory markers and relevant clinical cofactors, including gen …

Additionally, we analyzed differences between individuals with LC and those who recovered from COVID-19. Predictive models for …

78

Impact of vitamin D supplementation in the prognosis of patients with SARS-CoV2 pneumonia admitted to the intensive care unit - a randomized controlled trial.

Gonçalves AM, Rodrigues BS, Antunes ML, Gonçalves J, Marinho A. Gonçalves AM, et al. Front Immunol. 2025 Jun 5;16:1593200. doi: 10.3389/fimmu.2025.1593200. eCollection 2025. Front Immunol. 2025. PMID: 40539053 Free PMC article. Clinical Trial.

79

Vitamin D: recent advances, associated factors, and its role in combating non-communicable diseases.

Deepika, Kumari A, Singh S, Ahmad MF, Chaki D, Poria V, Kumar S, Saini N, Yadav N, Sangwan N, BinMowyna MN, Alsharari ZD, Kambal N, Min JH, Raposo A. Deepika, et al. NPJ Sci Food. 2025 Jun 13;9(1):100. doi: 10.1038/s41538-025-00460-5. NPJ Sci Food. 2025. PMID: 40514375 Free PMC article. Review.

Deficient levels, i.e., vitamin D deficiency in body can lead to the onset of chronic non-communicable illnesses. Vitamin D plays a direct and sometimes indirect role in the progression (when deficient) and prevention (when sufficient) of non-communica …

Deficient levels, i.e., vitamin D deficiency in body can lead to the onset of chronic non-communicable illnesses. Vitamin …

80

Reengineering Endogenous Targeting Lipid Nanoparticles (ENDO) for Systemic Delivery of mRNA to Pancreas.

Isaac I, Patel L, Tran N, Singam A, Yun D, Guha P, Park S, Bhattacharya C. Isaac I, et al. Adv Mater. 2025 Oct;37(40):e2507657. doi: 10.1002/adma.202507657. Epub 2025 Jun 12. Adv Mater. 2025. PMID: 40504743 Free PMC article.

Lipid nanoparticles (LNPs) hold transformative potential for nucleic acid delivery, with applications ranging from clinical use, particularly in COVID-19 vaccines, to gene therapy and cancer immunotherapy. However, a major limitation lies in their preferential accum …

Lipid nanoparticles (LNPs) hold transformative potential for nucleic acid delivery, with applications ranging from clinical use, particularl …

81

Integrative transcriptome-based drug repurposing in tuberculosis.

Samart K, Buskirk L, Tonielli A, Krishnan A, Ravi J. Samart K, et al. bioRxiv [Preprint]. 2025 Jun 2:2025.06.02.657296. doi: 10.1101/2025.06.02.657296. bioRxiv. 2025. PMID: 40501823 Free PMC article. Preprint.

Repurposed therapeutics have been successfully identified for cancer and COVID-19 by finding drugs that reverse disease gene expression patterns (an approach called 'connectivity scoring'), but this approach remains largely unexplored for bacterial infections like T …

Repurposed therapeutics have been successfully identified for cancer and COVID-19 by finding drugs that reverse disease gene e …

82

Biological mechanisms of pulmonary inflammation and its association with seropositive rheumatoid arthritis.

Yang P, Song Y, Li M. Yang P, et al. Front Immunol. 2025 May 23;16:1530753. doi: 10.3389/fimmu.2025.1530753. eCollection 2025. Front Immunol. 2025. PMID: 40486510 Free PMC article. Review.

This review thoroughly explores the mechanisms underlying early pulmonary lesions in seropositive RA, focusing on the mucosal barrier hypothesis, neutrophil extracellular traps, pathogenic microbial infections like COVID-19, Vitamin D, the microbiome a …

This review thoroughly explores the mechanisms underlying early pulmonary lesions in seropositive RA, focusing on the mucosal barrier hypoth …

83

Potential of fat-soluble vitamins as a platform for antiviral drug development.

Hirota Y, Okamoto M, Baba M, Suhara Y. Hirota Y, et al. Bioorg Med Chem Lett. 2025 Nov 1;127:130292. doi: 10.1016/j.bmcl.2025.130292. Epub 2025 Jun 6. Bioorg Med Chem Lett. 2025. PMID: 40484185 Free article. Review.

Vitamin A derivatives modulate immunity and inhibit viral replication, including SARS-CoV-2. Vitamin D analogs enhance immune responses and target viral enzymes, while vitamin E derivatives reduce oxidative stress and may directly inhibit viral replication. ...

Vitamin A derivatives modulate immunity and inhibit viral replication, including SARS-CoV-2. Vitamin D analogs enhance immune …

84

Vitamin D deficiency: A risk factor for antibody decline in COVID-19?

Bohl LP, Breser ML, Aguirre GE, Capello MI, Menichetti GI, Tiraboschi G, Rodríguez-Berdini L, Isaac P, Ángeles Fernández ML, Porporatto C. Bohl LP, et al. J Steroid Biochem Mol Biol. 2025 Oct;253:106809. doi: 10.1016/j.jsbmb.2025.106809. Epub 2025 Jun 6. J Steroid Biochem Mol Biol. 2025. PMID: 40484045

Data on weight, age, height, gender, symptoms, pre-existing conditions, vitamin D sources, and COVID-19 history were collected upon diagnosis, as well as 30 and 180 days post-diagnosis. Eighty-five percent of the patients experienced mild COVID- …

Data on weight, age, height, gender, symptoms, pre-existing conditions, vitamin D sources, and COVID-19 history …

85

Post-pandemic insights: Increased insulin resistance without dysglycemia in youths with overweight and obesity.

Sarıkaya E, Kara L, Suman Gök E, Berber U, Gül Şiraz Ü, Hatipoglu N. Sarıkaya E, et al. Pediatr Int. 2025 Jan-Dec;67(1):e70068. doi: 10.1111/ped.70068. Pediatr Int. 2025. PMID: 40457891

While there were no substantial variations in body mass index (BMI), BMI standard deviations (SD), glucose, glycosylated hemoglobin (HbA1c), and lipid profile, distinct changes were observed in insulin, homeostatic model assessment of insulin resistance (HOMA-IR), calcium, vit …

While there were no substantial variations in body mass index (BMI), BMI standard deviations (SD), glucose, glycosylated hemoglobin (HbA1c), …

86

Vitamin D status in children with mild, moderate, or severe confirmed COVID-19: systematic-review and meta-analysis.

Mousavi T, Moosazadeh M. Mousavi T, et al. Front Pediatr. 2025 May 13;13:1436633. doi: 10.3389/fped.2025.1436633. eCollection 2025. Front Pediatr. 2025. PMID: 40433474 Free PMC article.

BACKGROUND: Vitamin D acts as a pro-hormone with a wide range of beneficial effects. It is reported that vitamin D deficiency is a risk factor for COVID-19 severity in children. ...In addition, vitamin D deficiency and vi …

BACKGROUND: Vitamin D acts as a pro-hormone with a wide range of beneficial effects. It is reported that vitamin D …

87

Nutritional and Physical Rehabilitation in Post-Critical Coronavirus Disease 2019 (COVID-19) Ambulatory Patients: The NutriEcoMuscle Study.

Joaquín C, Bretón I, Ocón-Bretón MJ, Zabalegui A, Bellido D, Matía Martín P, Martínez-Olmos MÁ, Zugasti A, Riestra M, Botella F, García-Almeida JM; NutriEcoMuscle Study Team. Joaquín C, et al. Nutrients. 2025 May 20;17(10):1722. doi: 10.3390/nu17101722. Nutrients. 2025. PMID: 40431462 Free PMC article.

Background: The prevalence of malnutrition is high in post-intensive care unit (ICU) coronavirus disease 2019 (COVID-19) patients during hospitalization and after hospital discharge. This paper presents prospective results from the NutriEcoMuscle study, a multicente …

Background: The prevalence of malnutrition is high in post-intensive care unit (ICU) coronavirus disease 2019 (COVID-19) patie …

88

Clinical Characteristics of Vitamin D Deficiency Detected in Long COVID Patients During the Omicron Phase.

Matsuda Y, Sakurada Y, Nakano Y, Otsuka Y, Tokumasu K, Honda H, Soejima Y, Yokota Y, Takase R, Omura D, Otsuka F. Matsuda Y, et al. Nutrients. 2025 May 16;17(10):1692. doi: 10.3390/nu17101692. Nutrients. 2025. PMID: 40431432 Free PMC article.

Background: To characterize the clinical significance of vitamin D deficiency (VDD) detected in long COVID, a retrospective observational study was performed for outpatients who visited our clinic during the period from May 2024 to November 2024. Methods: Clinical t …

Background: To characterize the clinical significance of vitamin D deficiency (VDD) detected in long COVID, a retrospective ob …

89

Vitamin D and COVID-19: Clinical Evidence and Immunological Insights.

Caliman-Sturdza OA, Gheorghita RE, Soldanescu I. Caliman-Sturdza OA, et al. Life (Basel). 2025 Apr 30;15(5):733. doi: 10.3390/life15050733. Life (Basel). 2025. PMID: 40430160 Free PMC article. Review.

Vitamin D has emerged as a potential modulator of immune responses, sparking interest in its role in COVID-19 susceptibility and clinical outcomes. This review synthesizes current clinical evidence and explores immunological insights into the relations …

Vitamin D has emerged as a potential modulator of immune responses, sparking interest in its role in COVID-19 su …

90

Association of Vitamin D Supplementation with Glutathione Peroxidase (GPx) Activity, Interleukine-6 (IL-6) Levels, and Anxiety and Depression Scores in Patients with Post-COVID-19 Condition.

Ignacio-Mejía I, Bandala C, González-Zamora JF, Chavez-Galan L, Buendia-Roldan I, Pérez-Torres K, Rodríguez-Díaz MZ, Pacheco-Tobón DX, Quintero-Fabián S, Vargas-Hernández MA, Carrasco-Vargas H, Falfán-Valencia R, Pérez-Rubio G, Hernández-Lara KA, Gómez-Manzo S, Ortega-Cuellar D, Ignacio-Mejía F, Cárdenas-Rodríguez N. Ignacio-Mejía I, et al. Int J Mol Sci. 2025 May 10;26(10):4582. doi: 10.3390/ijms26104582. Int J Mol Sci. 2025. PMID: 40429727 Free PMC article.

Coronavirus disease 2019 (COVID-19) presents with various symptoms, and some patients develop post-COVID-19 condition (PCC). Vitamin D has shown therapeutic potential in COVID-19 and may offer benefits for PCC. The aim of th …

Coronavirus disease 2019 (COVID-19) presents with various symptoms, and some patients develop post-COVID-19 cond …

91

Serial Changes in Vitamin D Status in Patients During Severe Acute Respiratory Distress Syndrome and Extracorporeal Membrane Oxygenation.

Hermann M, Poslussny J, Gerger G, Haslacher H, Mayrhofer G, Tretter VE, Maleczek M, Ekmekcioglu C. Hermann M, et al. Medicina (Kaunas). 2025 May 16;61(5):901. doi: 10.3390/medicina61050901. Medicina (Kaunas). 2025. PMID: 40428859 Free PMC article.

This retrospective study primarily aimed to investigate the time-dependent changes in vitamin D levels and the correlation of vitamin D levels with disease severity and inflammatory markers in patients suffering from ARDS receiving ECMO therapy. ...Mos …

This retrospective study primarily aimed to investigate the time-dependent changes in vitamin D levels and the correlation of …

92

Analysis of the Use of Over-the-Counter Therapy for the Prevention and Treatment of COVID-19.

Vukosavljević I, Djorić N, Vukosavljević I, Milovanović J, Zdravković N, Djordjević K, Zdravković N, Kostić M, Barjaktarević A, Cupara S, Čekerevac I, Vasović N, Tomić Lučić A, Šorak M, Mirković N, Kostić O. Vukosavljević I, et al. Medicina (Kaunas). 2025 Apr 25;61(5):803. doi: 10.3390/medicina61050803. Medicina (Kaunas). 2025. PMID: 40428761 Free PMC article.

The respondents were patients seeking medical examination at the Health Center in Jagodina who had used over-the-counter medications during the COVID-19 pandemic. A total of 175 respondents participated in the study. The study design provided answers to questions ab …

The respondents were patients seeking medical examination at the Health Center in Jagodina who had used over-the-counter medications during …

93

Vitamin D Imbalance and Hydro-Electrolyte Disturbances in Hospitalized Children: A Comparation Between Post-COVID-19 Status and SARS-CoV-2/EBV Coinfection.

Petrea Cliveți CL, Ciortea DA, Gurău G, Matei NM, Dinu CA, Bergheș Oprea SE, Verga Răuță GI, Berbece SI. Petrea Cliveți CL, et al. Biomedicines. 2025 May 19;13(5):1233. doi: 10.3390/biomedicines13051233. Biomedicines. 2025. PMID: 40427060 Free PMC article.

Methods: Our retrospective-observational study included 406 hospitalized children with post-COVID-19 status or SARS-CoV-2/EBV coinfection. Results: Hypovitaminosis D was more common in the coinfected sublot (59.18%) than in the COVID-19 one (50.74%), w …

Methods: Our retrospective-observational study included 406 hospitalized children with post-COVID-19 status or SARS-CoV-2/EBV …

94

The dynamic linkage between covid-19 and nutrition: a review from a probiotics perspective using machine learning and bibliometric analysis.

Stefanis C, Tsigalou C, Bezirtzoglou I, Mitropoulou G, Voidarou C, Stavropoulou E. Stefanis C, et al. Front Nutr. 2025 May 9;12:1575130. doi: 10.3389/fnut.2025.1575130. eCollection 2025. Front Nutr. 2025. PMID: 40416372 Free PMC article.

Diet and nutrition could not fail to be studied in the context of combating the side effects of COVID-19. This study attempts to detect the relationship between dietary patterns and the disease of COVID-19 and emphasizes research on probiotics by mappi …

Diet and nutrition could not fail to be studied in the context of combating the side effects of COVID-19. This study attempts …

95

A Mixed-Methods Study Exploring the Feasibility of a Digital Combined Lifestyle Intervention for Patients With Post Covid-19 Condition.

Gach D, Born CDC, Schuurman LLT, van Osch FHM, van den Bergh JP, Gerards SMPL, Crutzen R, Schols AMWJ, Beijers RJHCG; P4O2 Consortium. Gach D, et al. Health Expect. 2025 Jun;28(3):e70299. doi: 10.1111/hex.70299. Health Expect. 2025. PMID: 40415473 Free PMC article.

INTRODUCTION: Low physical activity and poor dietary quality can negatively influence Covid-19 recovery and increase the risk and duration of post-Covid-19 condition (PCC). ...METHODS: A nested intervention study, incorporating motivational interviewin …

INTRODUCTION: Low physical activity and poor dietary quality can negatively influence Covid-19 recovery and increase the risk …

96

Vitamin D Serum Levels and the Development of Intensive Care Unit-Acquired Weakness: Insights from a COVID-19 Intensive Care Cohort.

Gulišija J, Čapkun V, Golic S, Stojanović Stipić S. Gulišija J, et al. Pathophysiology. 2025 May 9;32(2):21. doi: 10.3390/pathophysiology32020021. Pathophysiology. 2025. PMID: 40407601 Free PMC article.

The difference in vitamin D serum levels between the groups was not significantly different from zero (p = 0.567). All patients, except for one, were vitamin D insufficient. Conclusions: Vitamin D serum levels in the ICU-AW group were not …

The difference in vitamin D serum levels between the groups was not significantly different from zero (p = 0.567). All patient …

97

Exploring the interaction between vitamin D pathway gene polymorphisms, vitamin D status, and depression: A population-based study.

Sabião TDS, Menezes-Júnior LAA, Batista AP, Moura SS, Meireles AL, Menezes MC, Machado-Coelho GLL, Carraro JCC. Sabião TDS, et al. Nutrition. 2025 Sep;137:112802. doi: 10.1016/j.nut.2025.112802. Epub 2025 Apr 12. Nutrition. 2025. PMID: 40398311

A genetic risk score for vitamin D deficiency was developed based on gene polymorphisms involved in vitamin D metabolism (DHCR7, GC, and VDR), and this score was categorized into tertiles. ...Individuals with non-white skin color and vitamin …

A genetic risk score for vitamin D deficiency was developed based on gene polymorphisms involved in vitamin D me …

98

Prevalence of self-medication with vitamin or mineral supplements in the prevention and treatment of COVID-19: a systematic review and meta-analysis.

Rafati S, Rafati F, Shahabi N, Dastyar N, Arjmand F, Mousavi Nejad SM. Rafati S, et al. BMC Nutr. 2025 May 20;11(1):99. doi: 10.1186/s40795-025-01083-5. BMC Nutr. 2025. PMID: 40394722 Free PMC article.

BACKGROUND: Self-medication, as a self-care practice, increased dramatically during the COVID-19 pandemic. Among the most prevalent medications used for self-medication were vitamins and minerals. ...RESULTS: Out of 1424 non-duplicate studies, 56 were included in th …

BACKGROUND: Self-medication, as a self-care practice, increased dramatically during the COVID-19 pandemic. Among the most prev …

99

FokI polymorphism of the vitamin D receptor gene: Linking COVID-19 risk to genetic susceptibility in children.

Mohamed AA, Alanazi AT, Ahmed HH, Elfiky S, Abdel Ghafar MT, Maher I, Taha SA, AbuRahma MZA, Elagawy W, Mohareb DA, Rawy AM, Abostate HM, Youssef AA, Elsayed DS, Abdel-Hamid RM. Mohamed AA, et al. Cytokine. 2025 Jul;191:156958. doi: 10.1016/j.cyto.2025.156958. Epub 2025 May 13. Cytokine. 2025. PMID: 40367829

Vitamin D insufficiency was significantly more common in COVID-19 cases (18.2 % versus 3.7 %, p = 0.002). ...Additional research is required to validate the potential role of vitamin D and its receptor polymorphism in COVID-19 …

Vitamin D insufficiency was significantly more common in COVID-19 cases (18.2 % versus 3.7 %, p = 0.002). ...Add …

100

Cardiomyopathie dilatée hypocalcémique réversible induite par un hypoparathyroïdisme secondaire décompensé après une infection à la Covid-19 : à propos d’un cas.

Ejjebli S, Timimi AA, Ettagmouti Y, Benouna G, Arous S, Drighil A, Habbal R. Ejjebli S, et al. Ann Cardiol Angeiol (Paris). 2025 Jun;74(3):101899. doi: 10.1016/j.ancard.2025.101899. Epub 2025 May 8. Ann Cardiol Angeiol (Paris). 2025. PMID: 40345065 French.

She was treated with levothyroxine, calcitriol, and calcium and vitamin D supplements. Following a Covid-19 infection in May 2021, her hypoparathyroidism decompensated, leading to severe hypocalcemia, which was inadequately managed. ...Hypocalcemia fol …

She was treated with levothyroxine, calcitriol, and calcium and vitamin D supplements. Following a Covid-19 infe …

101

Serum vitamin D and the risk of SARS-CoV-2 and seasonal influenza infection during the twindemic period.

Ito A, Yamamoto S, Islam Z, Tan T, Oshiro Y, Inamura N, Nemoto T, Konishi M, Horii K, Mizoue T, Sugiura W, Ohmagari N. Ito A, et al. Clin Nutr ESPEN. 2025 Aug;68:263-266. doi: 10.1016/j.clnesp.2025.05.007. Epub 2025 May 6. Clin Nutr ESPEN. 2025. PMID: 40339959

Baseline vitamin D status was not associated with SARS-CoV-2 infection risk; the adjusted hazard ratios (95 % confidence intervals) for those with vitamin D insufficiency and deficiency, compared to those with vitamin D sufficiency, were …

Baseline vitamin D status was not associated with SARS-CoV-2 infection risk; the adjusted hazard ratios (95 % confidence inter …

102

Impact of vitamin D and zinc sufficiency on immune responses following COVID-19 vaccinations among healthcare workers.

Amadi C, Lawson SD, Okafor JC, Agbo E. Amadi C, et al. Clin Exp Vaccine Res. 2025 Apr;14(2):162-168. doi: 10.7774/cevr.2025.14.e17. Epub 2025 Mar 31. Clin Exp Vaccine Res. 2025. PMID: 40321789 Free PMC article.

Data (serum vitamin D/zinc, COVID-19 anti-spike immunoglobulin G [ASIgG]) were determined on the day of the first dose and repeated 4 weeks post-first dose and 4 weeks post-second dose. ...CONCLUSION: VitD and zinc sufficiency had a positive impact on …

Data (serum vitamin D/zinc, COVID-19 anti-spike immunoglobulin G [ASIgG]) were determined on the day of the firs …

103

COVID-19 rapid guideline: managing COVID-19.

[No authors listed] [No authors listed] London: National Institute for Health and Care Excellence (NICE); 2025 May 1. London: National Institute for Health and Care Excellence (NICE); 2025 May 1. PMID: 34181371 Free Books & Documents. Review.

This guideline covers managing COVID-19 in babies, children, young people and adults in community and hospital settings. ...NICE has also produced COVID-19 rapid guidelines on managing long-term effects of COVID-19 ('long COVID') and haem …

This guideline covers managing COVID-19 in babies, children, young people and adults in community and hospital settings. ...NI …

104

Effect of the vitamin D supplementation on clinical outcomes and inflammatory status in COVID-19 patients: an umbrella review.

Jafari-Vayghan H, Rahimlou M, Almasi-Hashiani A, Aframehr E, Saleh-Ghadimi S. Jafari-Vayghan H, et al. BMC Nutr. 2025 Apr 29;11(1):86. doi: 10.1186/s40795-025-01060-y. BMC Nutr. 2025. PMID: 40301951 Free PMC article.

INTRODUCTION: The role of vitamin D supplementation in modulating clinical outcomes and inflammatory responses in COVID- 19 patients has garnered significant interest. ...Studies assessing the impact of vitamin D supplementation on diseas …

INTRODUCTION: The role of vitamin D supplementation in modulating clinical outcomes and inflammatory responses in COVID …

105

The Impact of Vitamin D in the Prevention of Influenza, COVID-19, and Dengue: A Review.

Galindo-Méndez M, Galindo-Ruiz M, Concheso-Venegas MF, Mendoza-Molina SU, Orozco-Cruz D, Weintraub-Benzion E. Galindo-Méndez M, et al. Biomedicines. 2025 Apr 9;13(4):927. doi: 10.3390/biomedicines13040927. Biomedicines. 2025. PMID: 40299497 Free PMC article. Review.

Since its discovery, vitamin D (VD) has been known for its implications in maintaining bone homeostasis. However, in recent years it has been discovered that the vitamin D receptor is expressed on different cells of the immune system and that these cel …

Since its discovery, vitamin D (VD) has been known for its implications in maintaining bone homeostasis. However, in recent ye …

106

Dissecting clinical features of COVID-19 in a cohort of 21,312 acute care patients.

Maguire C, Soloveichik E, Blinchevsky N, Miller J, Morrison R, Busch J, Michael Brode W, Wylie D, Rousseau J, Melamed E. Maguire C, et al. Commun Med (Lond). 2025 Apr 25;5(1):138. doi: 10.1038/s43856-025-00844-4. Commun Med (Lond). 2025. PMID: 40281203 Free PMC article.

To address this gap, we conducted a retrospective analysis of electronic health records from COVID-19 patients over 2.5 years of the COVID-19 pandemic to identify associated clinical features. ...Interestingly, low albumin is one of the best lab predic …

To address this gap, we conducted a retrospective analysis of electronic health records from COVID-19 patients over 2.5 years …

107

Vitamin D Status and Incidence of SARS-CoV-2 Reinfections in the Borriana COVID-19 Cohort: A Population-Based Prospective Cohort Study.

Domènech-Montoliu S, López-Diago L, Aleixandre-Gorriz I, Pérez-Olaso Ó, Sala-Trull D, Rio-González AD, Pac-Sa MR, Sánchez-Urbano M, Satorres-Martinez P, Casanova-Suarez J, Notari-Rodriguez C, Ruiz-Puig R, Badenes-Marques G, Aparisi-Esteve L, Domènech-León C, Romeu-Garcia MA, Arnedo-Pena A. Domènech-Montoliu S, et al. Trop Med Infect Dis. 2025 Apr 6;10(4):98. doi: 10.3390/tropicalmed10040098. Trop Med Infect Dis. 2025. PMID: 40278771 Free PMC article.

A deficient vitamin D (VitD) status has been associated with SARS-CoV-2 infections, severity, and mortality. ...

108

The impact of vitamin D on atopic disorders: assessing evidence for a causal relationship.

Zúñiga VA, Bazan-Perkins B. Zúñiga VA, et al. Front Nutr. 2025 Apr 10;12:1584818. doi: 10.3389/fnut.2025.1584818. eCollection 2025. Front Nutr. 2025. PMID: 40276536 Free PMC article.

Since the beginning of COVID-19 pandemic, there has been a noticeable increase in the consumption of vitamin D. ...However, although the literature on vitamin D and atopy has yielded controversial results, multiple studies have described …

Since the beginning of COVID-19 pandemic, there has been a noticeable increase in the consumption of vitamin D. …

109

A comparative study of the effects of the COVID-19 pandemic on semen quality based on a nationwide relaxation of COVID-19 restrictions in China at the end of 2022.

Zhang S, Zhang T, Ren J, Feng K, Xia Y, Lu H, Liu M, Guo H, Duan G, Zhang G, Cao J. Zhang S, et al. Transl Androl Urol. 2025 Mar 30;14(3):715-728. doi: 10.21037/tau-24-562. Epub 2025 Mar 26. Transl Androl Urol. 2025. PMID: 40226063 Free PMC article.

This study aimed to investigate the effects of the COVID-19 pandemic on semen quality. Based on a large-scale ecological comparative study, our study analyzed the impact of the COVID-19 pandemic on semen quality after the national liberalization of res …

This study aimed to investigate the effects of the COVID-19 pandemic on semen quality. Based on a large-scale ecological compa …

110

Systematic Review of the Impact of COVID-19 on Healthcare Systems and Society-The Role of Diagnostics and Nutrition in Pandemic Response.

Olesińska W, Biernatek M, Lachowicz-Wiśniewska S, Piątek J. Olesińska W, et al. J Clin Med. 2025 Apr 4;14(7):2482. doi: 10.3390/jcm14072482. J Clin Med. 2025. PMID: 40217931 Free PMC article. Review.

The COVID-19 pandemic has revealed deep vulnerabilities in healthcare systems and public health preparedness. ...A total of 88 studies were analyzed, encompassing diagnostics, micronutrient deficiencies (notably vitamin D, C, E, zinc, and selenium), an …

The COVID-19 pandemic has revealed deep vulnerabilities in healthcare systems and public health preparedness. ...A total of 88 …

111

Correction: Vitamin D: a key player in COVID-19 immunity and lessons from the pandemic to combat immune-evasive variants.

Sabit H, Abdel-Ghany S, Abdallah MS, Abul-Maaty O, Khoder AI, Shoman NA, Farrag MS, Martasek P, Noreddin AM, Nazih M. Sabit H, et al. Inflammopharmacology. 2025 Jun;33(6):3513-3514. doi: 10.1007/s10787-025-01725-x. Inflammopharmacology. 2025. PMID: 40216663 Free PMC article. No abstract available.

112

Impact of vitamin D levels on mortality in older covid-19 vaccinated patients.

Ceolin C, Vergadoro M, Simonato C, Cazzavillan S, Papa MV, Trapella GS, Di Marzio B, Sermasi R, Zanforlini BM, Curreri C, Bertocco A, Devita M, Coin A, Spiezia L, Sergi G, De Rui M. Ceolin C, et al. BMC Geriatr. 2025 Apr 10;25(1):240. doi: 10.1186/s12877-025-05873-1. BMC Geriatr. 2025. PMID: 40211163 Free PMC article.

No significant differences were found in COVID-19 severity among the three groups. After 12 months, 24 deaths were recorded: 17% in unvaccinated, 19% in vaccinated with low vitamin D, and 20% in vaccinated with high vitamin D (p = 0.94). …

No significant differences were found in COVID-19 severity among the three groups. After 12 months, 24 deaths were recorded: 1 …

113

Case fatality rate of zoonotic SARS.CoV2 and associated risk factors in the Libyan population.

Alemam HA, Mahmoud AS, Abdunnabi MA, Ellafi AM, Elfahem AA, Ibrahim KM, El Meshri SE, Elzghied A. Alemam HA, et al. Open Vet J. 2025 Feb;15(2):885-892. doi: 10.5455/OVJ.2025.v15.i2.37. Epub 2025 Feb 28. Open Vet J. 2025. PMID: 40201821 Free PMC article.

Among these potential risk factors were animal welfare, vitamin D levels, the ABO system, lymphocyte count (level), and healthy status. In contrast, the results showed that other risk factors were not significantly associated with the CFR. ...A large set of prospect …

Among these potential risk factors were animal welfare, vitamin D levels, the ABO system, lymphocyte count (level), and health …

114

Investigating the relationship between cycle threshold of SARS-CoV-2 RT-PCR, clinical features, and laboratory data in hospitalized COVID-19 patients in Semnan, Iran.

Kalantar Neyestanaki MH, Gholizadeh O, Yasamineh S, Tarahomi M, Pooya P, Eslami M, Dadashpour M, Ghaffari H. Kalantar Neyestanaki MH, et al. Front Cell Infect Microbiol. 2025 Mar 24;15:1522375. doi: 10.3389/fcimb.2025.1522375. eCollection 2025. Front Cell Infect Microbiol. 2025. PMID: 40196044 Free PMC article.

INTRODUCTION: COVID-19, caused by the SARS-CoV-2 virus, has emerged as a global public health crisis. ...Correlation analysis revealed associations between age, CRP, Cr, BUN, FBS, Vitamin D, TG, LDL, HDL, AST, ALP, and SPo2. Reflecting complex interact …

INTRODUCTION: COVID-19, caused by the SARS-CoV-2 virus, has emerged as a global public health crisis. ...Correlation analysis …

115

Vitamin D deficiency in a subfertility population and the impact of COVID-19 lockdowns.

Windrim CM, Kane D, Kelleher G, Mocanu E. Windrim CM, et al. Int J Gynaecol Obstet. 2025 Sep;170(3):1199-1204. doi: 10.1002/ijgo.70124. Epub 2025 Apr 7. Int J Gynaecol Obstet. 2025. PMID: 40192512 Free PMC article.

OBJECTIVE: To evaluate the burden of vitamin D deficiency in female patients attending a fertility clinic in a tertiary referral center, assess temporal trends-including the potential impact of COVID-19 lockdowns-and explore socioeconomic disparities i …

OBJECTIVE: To evaluate the burden of vitamin D deficiency in female patients attending a fertility clinic in a tertiary referr …

116

Vaccination and food consumption: association with Post-Acute COVID-19 Syndrome in Brazilian adults (CUME Study).

Brandão ML, Hermsdorff HHM, Leal ACG, Bressan J, Pimenta AM. Brandão ML, et al. Front Nutr. 2025 Mar 14;12:1549747. doi: 10.3389/fnut.2025.1549747. eCollection 2025. Front Nutr. 2025. PMID: 40161300 Free PMC article.

BACKGROUND: Post-Acute COVID-19 Syndrome (PACS) is an important sequalae of COVID-19. Then, our objective was to analyze the risk and protective factors for PACS in Brazilian adults participating in the Cohort of Universities of Minas Gerais (CUME Stud …

BACKGROUND: Post-Acute COVID-19 Syndrome (PACS) is an important sequalae of COVID-19. Then, our objective was to …

117

Clinical and biochemical spectrum of APOB-related hypobetalipoproteinemia: Insights from a retrospective cohort study.

Sürücü Kara İ, Köse E, Mutlu H, Sanrı A, Tarugi P, Eminoğlu FT. Sürücü Kara İ, et al. J Clin Lipidol. 2025 May-Jun;19(3):605-616. doi: 10.1016/j.jacl.2025.02.003. Epub 2025 Feb 8. J Clin Lipidol. 2025. PMID: 40155282

Vitamin E deficiency was identified in 26.7%, vitamin A deficiency in 13.3%, and vitamin D insufficiency in 66.7% of cases. Liver ultrasonography revealed hepatosteatosis in 73.3% of patients. ...Among the families, 3 had members who died due to complications relate …

Vitamin E deficiency was identified in 26.7%, vitamin A deficiency in 13.3%, and vitamin D insufficiency in 66.7% of cases. Li …

118

Retrospective Clinical Investigation into the Association Between Abnormal Blood Clotting, Oral Anticoagulant Therapy, and Medium-Term Mortality in a Cohort of COVID-19 Patients.

Dinoi G, Togo MV, Guida P, Deruvo C, Samarelli F, Imbrici P, Nicolotti O, De Luca A, Mastroianni F, Liantonio A, Altomare CD. Dinoi G, et al. Biomedicines. 2025 Feb 20;13(3):535. doi: 10.3390/biomedicines13030535. Biomedicines. 2025. PMID: 40149514 Free PMC article.

Background/Objectives: People affected by COVID-19 are exposed to abnormal clotting and endothelial dysfunction, which may trigger thromboembolic events. ...Conclusions: This retrospective clinical study furnished evidences of the impact of OAT, comorbidities and ot …

Background/Objectives: People affected by COVID-19 are exposed to abnormal clotting and endothelial dysfunction, which may tri …

119

Vitamin D: A Nutraceutical Supplement at the Crossroad Between Respiratory Infections and COVID-19.

Rizzi M, Sainaghi PP. Rizzi M, et al. Int J Mol Sci. 2025 Mar 12;26(6):2550. doi: 10.3390/ijms26062550. Int J Mol Sci. 2025. PMID: 40141190 Free PMC article. Review.

Ecological and observational studies support a relationship between hypovitaminosis D and COVID-19 negative outcomes and, according to this evidence, several research groups investigated the role of vitamin D supplementation in protecting from SARS-CoV …

Ecological and observational studies support a relationship between hypovitaminosis D and COVID-19 negative outcomes and, acco …

120

Vitamin D supplementation for managing COVID-19 in patients with vitamin D deficiency: a systematic review and meta-analysis of randomised controlled trials.

Zhu L, Zhang Y, Li X, Zou X, Bing P, Qi M, He B. Zhu L, et al. BMJ Open. 2025 Mar 26;15(3):e091903. doi: 10.1136/bmjopen-2024-091903. BMJ Open. 2025. PMID: 40139702 Free PMC article.

OBJECTIVES: Vitamin D deficiency is prevalent among the population. Previous studies have shown that vitamin D supplementation might be useful for treating COVID-19 infection. Therefore, we performed a meta-analysis to explore vitamin …

OBJECTIVES: Vitamin D deficiency is prevalent among the population. Previous studies have shown that vitamin D s …

121

Influence of military preventive policy for recruit training on COVID-19 seroconversion: the IMPACT-COVID-19 study.

Stacey MJ, Ferentinos P, Koivula F, Parsons IT, Gifford RM, Snape D, Nicholson-Little A, Faustini S, Walsh NP, Lamb LE, O'Shea MK, Richter AG, Greeves JP, O'Hara J, Woods D. Stacey MJ, et al. BMJ Mil Health. 2025 Mar 22:military-2024-002940. doi: 10.1136/military-2024-002940. Online ahead of print. BMJ Mil Health. 2025. PMID: 40122532

Potential association between lower vitamin D status and increased infection risk was also highlighted. We aimed to prospectively determine seroconversion and test the hypothesis that this would vary with vitamin D supplementation in representative pop …

Potential association between lower vitamin D status and increased infection risk was also highlighted. We aimed to prospectiv …

122

Association of VDR and TMPRSS2 gene polymorphisms with COVID-19 severity: a computational and clinical study.

Verma S, Verma S, Siddiqi Z, Raza ST, Faruqui T, Ansari AI, Abbas M, Mahdi F. Verma S, et al. Mol Biol Rep. 2025 Mar 19;52(1):327. doi: 10.1007/s11033-025-10417-2. Mol Biol Rep. 2025. PMID: 40106000

BACKGROUND: COVID-19 manifestations range from asymptomatic to severe, and are influenced by host genetic factors. This study examined the association between vitamin D receptor (VDR) polymorphisms (TaqI and FokI) and transmembrane serine protease 2 (T …

BACKGROUND: COVID-19 manifestations range from asymptomatic to severe, and are influenced by host genetic factors. This study …

123

Efficacy of vitamin D replacement therapy on 28 cases of myalgic encephalomyelitis/chronic fatigue syndrome after COVID-19 vaccination.

Kodama S, Konishi N, Hirai Y, Fujisawa A, Nakata M, Teramukai S, Fukushima M. Kodama S, et al. Nutrition. 2025 Jun;134:112718. doi: 10.1016/j.nut.2025.112718. Epub 2025 Feb 18. Nutrition. 2025. PMID: 40090177 Free article.

CONCLUSIONS: For patients developing ME/CFS after COVID-19 vaccination with insufficient or deficient vitamin D levels, appropriate vitamin D replacement therapy under medical guidance may lead to symptomatic relief. We are preparing a ra …

CONCLUSIONS: For patients developing ME/CFS after COVID-19 vaccination with insufficient or deficient vitamin D …

124

High-dose vitamin D(3) to improve outcomes in the convalescent phase of complicated severe acute malnutrition in Pakistan: a double-blind randomised controlled trial (ViDiSAM).

Saleem J, Zakar R, Butt MS, Kaleem R, Chaudhary A, Chandna J, Jolliffe DA, Piper J, Abbas Z, Tang JCY, Fraser WD, Freemantle N, Prendergast AJ, Martineau AR. Saleem J, et al. Nat Commun. 2025 Mar 15;16(1):2554. doi: 10.1038/s41467-025-57803-9. Nat Commun. 2025. PMID: 40089464 Free PMC article. Clinical Trial.

We have previously shown that high-dose vitamin D(3) improved weight gain and neurodevelopmental indices in children receiving standard therapy for uncomplicated severe acute malnutrition (SAM). ...The trial has now completed. 259 children were randomised (128 to …

We have previously shown that high-dose vitamin D(3) improved weight gain and neurodevelopmental indices in children receiving …

125

Characterizing Public Sentiments and Drug Interactions in the COVID-19 Pandemic Using Social Media: Natural Language Processing and Network Analysis.

Li W, Hua Y, Zhou P, Zhou L, Xu X, Yang J. Li W, et al. J Med Internet Res. 2025 Mar 5;27:e63755. doi: 10.2196/63755. J Med Internet Res. 2025. PMID: 40053730 Free PMC article.

This study aimed to develop a natural language processing (NLP) pipeline tailored for the analysis of social media discourse on COVID-19-related drugs. METHODS: This study constructed a full pipeline for COVID-19-related drug tweet analysis, using pret …

This study aimed to develop a natural language processing (NLP) pipeline tailored for the analysis of social media discourse on COVID …

126

Non-pharmacologic Prevention of Acute Exacerbation Chronic Obstructive Pulmonary Disease.

Choi JY. Choi JY. Tuberc Respir Dis (Seoul). 2025 Jul;88(3):419-430. doi: 10.4046/trd.2024.0155. Epub 2025 Mar 7. Tuberc Respir Dis (Seoul). 2025. PMID: 40051185 Free PMC article.

Smoking cessation remains a critical intervention, while the role of electronic cigarettes remains debatable; some evidence suggests they may help patients unable to quit tobacco smoking. Vitamin D supplementation has shown potential in reducing exacerbations, parti …

Smoking cessation remains a critical intervention, while the role of electronic cigarettes remains debatable; some evidence suggests they ma …

127

Vitamin D status in children with COVID-19: does it affect the development of long COVID and its symptoms?

Perestiuk V, Kosovska T, Dyvoniak O, Volianska L, Boyarchuk O. Perestiuk V, et al. Front Pediatr. 2025 Feb 14;13:1507169. doi: 10.3389/fped.2025.1507169. eCollection 2025. Front Pediatr. 2025. PMID: 40046855 Free PMC article.

RESULTS: In total, 162 hospitalized patients with COVID-19 were examined. Vitamin D deficiency was determined in 8.0%, insufficiency in 25.3%, and optimal levels in 66.7% of children with COVID-19. ...CONCLUSION: The 25(OH)D concentration …

RESULTS: In total, 162 hospitalized patients with COVID-19 were examined. Vitamin D deficiency was determined in …

128

The protective role of vitamin D in BNT162b2 vaccine-related acute myocarditis.

Tsang HW, Chua GT, Tung KTS, Wong RSM, Tsao SSL, Wong JSC, Tung JYL, Kwok JSY, Yam JCS, Chan GCF, To KKW, Wong ICK, Leung WH, Kwan MYW, Ip P. Tsang HW, et al. Front Immunol. 2025 Feb 19;16:1501609. doi: 10.3389/fimmu.2025.1501609. eCollection 2025. Front Immunol. 2025. PMID: 40046048 Free PMC article.

INTRODUCTION: Vaccine-related myocarditis is recognized as a rare but important complication, especially after mass-scale mRNA COVID-19 vaccination. Knowledge regarding how to minimize the risk is limited. As NK cells can mediate acute myocarditis after mRNA COVI …

INTRODUCTION: Vaccine-related myocarditis is recognized as a rare but important complication, especially after mass-scale mRNA COVID- …

129

Impact of Vitamin D Levels on Clinical Outcomes in SARS-CoV-2 Infections.

Najih M, Boussettine R, El Kehel MS, Nabil K, Azmi H, Berradi H, Ennaji MM. Najih M, et al. Cureus. 2025 Jan 31;17(1):e78291. doi: 10.7759/cureus.78291. eCollection 2025 Jan. Cureus. 2025. PMID: 40026986 Free PMC article.

Given the need for effective strategies to reduce infection rates, disease progression, and severity, this study aimed to investigate the potential role of vitamin D (25OHD) in mitigating the severity of COVID-19. METHODS: A cross-sectional study was c …

Given the need for effective strategies to reduce infection rates, disease progression, and severity, this study aimed to investigate the po …

130

Evaluating the utilisation patterns of pharmacological therapy in COVID-19 patients: an ecological study in Italy.

Marino ML, Di Filippo A, Onder G, Eleuteri D, Trotta F. Marino ML, et al. BMJ Public Health. 2025 Feb 26;3(1):e001767. doi: 10.1136/bmjph-2024-001767. eCollection 2025. BMJ Public Health. 2025. PMID: 40017974 Free PMC article.

BACKGOUND: The drug central monitoring system set up in Italy to evaluate the real-time trends of medicines used in hospital and primary care settings contributed to inform drug supplies, avoided stockpiling and allowed to monitor adherence to clinical practice guidelines for the …

BACKGOUND: The drug central monitoring system set up in Italy to evaluate the real-time trends of medicines used in hospital and primary car …

131

Impact of Vitamins, Antibiotics, Probiotics, and History of COVID-19 on the Gut Microbiome in Ulcerative Colitis Patients: A Cross-Sectional Study.

Straume Z, Krūmiņa N, Elbere I, Rozenberga M, Erts R, Rudzīte D, Proskurina A, Krumina A. Straume Z, et al. Medicina (Kaunas). 2025 Feb 7;61(2):284. doi: 10.3390/medicina61020284. Medicina (Kaunas). 2025. PMID: 40005401 Free PMC article.

All patients were divided into groups based on history of COVID-19 (COVID-19 positive vs. COVID-19 negative) in the last six months. Information about antibiotic, probiotic, and vitamin intake were outlined, and faecal samples were collec …

All patients were divided into groups based on history of COVID-19 (COVID-19 positive vs. COVID-19 …

132

Analysis of Biomarker Levels in Nasopharyngeal Swabs, Serum, and Saliva Across Different Health Conditions.

Pencheva M, Manchorova-Veleva N, Baruh D, Rusinov G, Vangelov L. Pencheva M, et al. Life (Basel). 2025 Feb 19;15(2):324. doi: 10.3390/life15020324. Life (Basel). 2025. PMID: 40003732 Free PMC article.

BACKGROUND: Coronavirus disease 2019 (COVID-19) is associated with a wide variety of clinical manifestations. AIM: This study aims to evaluate the levels of angiotensin-converting enzyme 2 (ACE2), metalloprotease 17 (ADAM17), Interleukin-17A (IL-17A), transmembrane …

BACKGROUND: Coronavirus disease 2019 (COVID-19) is associated with a wide variety of clinical manifestations. AIM: This study …

133

COVID-19 and our understanding of vitamin D and immune function.

Hewison M. Hewison M. J Steroid Biochem Mol Biol. 2025 May;249:106710. doi: 10.1016/j.jsbmb.2025.106710. Epub 2025 Feb 20. J Steroid Biochem Mol Biol. 2025. PMID: 39986580 Free article. Review.

This was due, in part, to the many association studies of vitamin D status and COVID-19 infection and disease prognosis, as well as the smaller number of clinical trials of vitamin D supplementation. However, a potential role for vitam …

This was due, in part, to the many association studies of vitamin D status and COVID-19 infection and disease pr …

134

Proteomics Reveals That Vitamin D Deficiency Leads to Immunoglobulin Abnormalities and Immune Dysregulation in Patients with Post-COVID-19 Condition.

Ji W, Xie X, Bai G, Fan Y, He Y, Zhang L, Zhou H, Li L, Li H. Ji W, et al. J Proteome Res. 2025 Mar 7;24(3):1449-1461. doi: 10.1021/acs.jproteome.4c01120. Epub 2025 Feb 20. J Proteome Res. 2025. PMID: 39979118

Vitamin D (VD) levels are closely related to the occurrence of post-COVID-19 conditions (PCCs), but the specific mechanism is still unclear. ...

Vitamin D (VD) levels are closely related to the occurrence of post-COVID-19 conditions (PCCs), but the specific …

135

Evidence of rapid rise in population immunity from SARS-CoV-2 subclinical infections through pre-vaccination serial serosurveys in Pakistan.

Iqbal J, Hasan Z, Habib MA, Malik AA, Muhammad S, Begum K, Zuberi R, Umer M, Ikram A, Soofi SB, Cousens S, Bhutta ZA. Iqbal J, et al. J Glob Health. 2025 Feb 21;15:04078. doi: 10.7189/jogh.15.04078. J Glob Health. 2025. PMID: 39977666 Free PMC article.

We measured antibodies in sera and tested a subset of respiratory samples for COVID-19 using polymerase chain reaction (PCR) and antigen tests, also measuring haemoglobin (Hb), C-reactive protein (CRP), vitamin D, and zinc in round 1. ...Most participa …

We measured antibodies in sera and tested a subset of respiratory samples for COVID-19 using polymerase chain reaction (PCR) a …

136

High-dose vitamin D supplementation in patients with severe acute respiratory syndrome coronavirus 2 pneumonia hospitalized in a polyvalent intensive care unit: A retrospective cohort study.

Vasconcelos M, Rodrigues BS, Gonçalves A. Vasconcelos M, et al. Nutr Clin Pract. 2025 Aug;40(4):893-900. doi: 10.1002/ncp.11277. Epub 2025 Feb 19. Nutr Clin Pract. 2025. PMID: 39968734

BACKGROUND AND AIMS: The health benefits of vitamin D are far beyond bone mineral metabolism. Vitamin D has immunomodulator and anti-inflammatory properties and its role in critically ill patients is controversial. ...CONCLUSION: High-dose vitamin …

BACKGROUND AND AIMS: The health benefits of vitamin D are far beyond bone mineral metabolism. Vitamin D has immu …

137

Vitamin D Deficiency-Induced Proximal Myopathy in a Pediatric Patient During COVID-19 Lockdown: A Case Report.

Hazique M, Surana A, Mehta A, Huang H, Alneyadi S, Shah K, Singh A, Varma A, Singh MP, Sah S, Verma A. Hazique M, et al. Clin Med Insights Case Rep. 2025 Feb 13;18:11795476251320006. doi: 10.1177/11795476251320006. eCollection 2025. Clin Med Insights Case Rep. 2025. PMID: 39950105 Free PMC article.

Vitamin D deficiency is a significant public health concern that affects bone health and muscle function in children, especially in developing countries. The COVID-19 pandemic has intensified this issue because lockdowns have reduced sunlight exposure. …

Vitamin D deficiency is a significant public health concern that affects bone health and muscle function in children, especial …

138

Vitamin D Deficiency Meets Hill's Criteria for Causation in SARS-CoV-2 Susceptibility, Complications, and Mortality: A Systematic Review.

Wimalawansa SJ. Wimalawansa SJ. Nutrients. 2025 Feb 6;17(3):599. doi: 10.3390/nu17030599. Nutrients. 2025. PMID: 39940457 Free PMC article.

This SR establishes a strong inverse relationship between 25(OH)D levels and SARS-CoV-2 vulnerability, meeting Hill's criteria. Vitamin D(3) and calcifediol reduce infections, complications, hospitalizations, and deaths by ~50%, outperforming all patented, FDA-appro …

This SR establishes a strong inverse relationship between 25(OH)D levels and SARS-CoV-2 vulnerability, meeting Hill's criteria. Vitamin …

139

The Immunomodulatory Activity of High Doses of Vitamin D in Critical Care Patients with Severe SARS-CoV-2 Pneumonia-A Randomized Controlled Trial.

Gonçalves AM, Velho S, Rodrigues B, Antunes ML, Cardoso M, Godinho-Santos A, Gonçalves J, Marinho A. Gonçalves AM, et al. Nutrients. 2025 Jan 31;17(3):540. doi: 10.3390/nu17030540. Nutrients. 2025. PMID: 39940396 Free PMC article. Clinical Trial.

Vitamin D receptor [VDR] expression promotes LL37 expression, possibly contributing to host defense. ...

140

Effect of Moderately High-Dose Vitamin D3 Supplementation on Mortality in Patients Hospitalized for COVID-19 Infection.

Sümegi LD, Varga M, Kadocsa V, Szili B, Stempler M, Lakatos PA, Németh Z, Takács I. Sümegi LD, et al. Nutrients. 2025 Jan 30;17(3):507. doi: 10.3390/nu17030507. Nutrients. 2025. PMID: 39940365 Free PMC article.

In our retrospective study, we aimed to investigate the impact of vitamin D deficiency and moderately high-dose vitamin D3 supplementation on mortality and disease outcomes in patients with COVID-19 infection. ...CONCLUSIONS: The supplemental dosage, 3 …

In our retrospective study, we aimed to investigate the impact of vitamin D deficiency and moderately high-dose vitamin D3 sup …

141

Morphometric vertebral fractures at hospitalization associate with Long COVID occurrence.

di Filippo L, Doga M, Mangini F, Gifuni L, Sahagun SJ, Rovere Querini P, Rosen CJ, Giustina A. di Filippo L, et al. J Endocrinol Invest. 2025 Jun;48(6):1371-1382. doi: 10.1007/s40618-025-02544-1. Epub 2025 Feb 11. J Endocrinol Invest. 2025. PMID: 39932650

Osteoporosis and vertebral fractures (VFs) were associated with worse acute COVID-19 and impaired respiratory recovery after hospitalization. Therefore, we aimed to assess the potential relationship between VFs and the occurrence of the Long COVID syndrome. METHODS: …

Osteoporosis and vertebral fractures (VFs) were associated with worse acute COVID-19 and impaired respiratory recovery after h …

142

Investigation of vitamin D deficiency in girls with growth and development variations-a single center study.

Huang P, Zeng B, Ren F, Zhou Y, Li Y, Huang Y, Liu X, Zhou J, Ma Y. Huang P, et al. Front Pediatr. 2025 Jan 27;13:1518548. doi: 10.3389/fped.2025.1518548. eCollection 2025. Front Pediatr. 2025. PMID: 39931653 Free PMC article.

PURPOSE: To understand the status of vitamin D deficiency in girls with growth and developmental variations, as well as the impact of COVID-19 on their vitamin D levels, and to provide reference for the prevention and treatment of vita …

PURPOSE: To understand the status of vitamin D deficiency in girls with growth and developmental variations, as well as the im …

143

Vitamin D as an Adjuvant Immune Enhancer to SARS-Cov-2 Vaccine.

Salamony A, Abdelsalam M, Elguindy N, Roshdy WH, Youssef A, Shamikh Y. Salamony A, et al. Curr Microbiol. 2025 Feb 7;82(3):122. doi: 10.1007/s00284-025-04095-3. Curr Microbiol. 2025. PMID: 39918738

The samples were analyzed using a chemiluminescent immunoassay to measure vitamin D level and titer of neutralizing and IgG antibodies. A lower level of neutralizing antibodies was detected in deficient and insufficient vitamin D-vaccinated individuals …

The samples were analyzed using a chemiluminescent immunoassay to measure vitamin D level and titer of neutralizing and IgG an …

144

Variations in vitamin D status among Chinese children aged 1-6 years during the COVID-19 pandemic.

Qiao Y, Wang X, Ma Y, Hu J. Qiao Y, et al. Front Public Health. 2025 Jan 23;13:1514355. doi: 10.3389/fpubh.2025.1514355. eCollection 2025. Front Public Health. 2025. PMID: 39916704 Free PMC article.

BACKGROUND: Vitamin D deficiency has been a critical global health issue within the pediatric population. Closed-off management brought about by the COVID-19 pandemic has drastically impacted outdoor activities and sunlight exposure, however, whether i …

BACKGROUND: Vitamin D deficiency has been a critical global health issue within the pediatric population. Closed-off managemen …

145

Association Between Vitamin D and COVID-19-Related Outcomes: An Umbrella Review of Meta-Analyses.

Yang JM, Li ZQ, Zhong YB, Xie HY, Luo Y, Xiao L, Liao JH, Wang MY. Yang JM, et al. Nutr Rev. 2025 Sep 1;83(9):1757-1770. doi: 10.1093/nutrit/nuae225. Nutr Rev. 2025. PMID: 39907316

CONTEXT: COVID-19 remains globally pandemic, and although several meta-analyses have explored the association between vitamin D and COVID-19 relative to clinical outcomes, a unified view has not yet emerged. ...CONCLUSIONS: Low vitamin …

CONTEXT: COVID-19 remains globally pandemic, and although several meta-analyses have explored the association between vitam …

146

Vitamin D deficiency presenting as seizures.

Sagar A, Datta G, Jayaraman M. Sagar A, et al. Med J Armed Forces India. 2025 Jan-Feb;81(1):105-108. doi: 10.1016/j.mjafi.2023.11.010. Epub 2024 Jan 16. Med J Armed Forces India. 2025. PMID: 39872193 Free PMC article.

However, severe hypocalcemia secondary to vitamin D deficiency, manifesting as seizures is uncommon. We present a series of such cases encountered by us in the time frame of June 2020 to Dec 2021 (the first wave of the Covid-19 pandemic associated with …

However, severe hypocalcemia secondary to vitamin D deficiency, manifesting as seizures is uncommon. We present a series of su …

147

Role of serum fibroblast growth factor-23 and Klotho level in COVID-19 infection-related mortality: a prospective study.

Akin D, Aydogan BB, Emre N, Gundogdu G, Ozmen S, Erkek OK, Alpua M. Akin D, et al. J Infect Dev Ctries. 2024 Dec 31;18(12.1):S326-S330. doi: 10.3855/jidc.20272. J Infect Dev Ctries. 2024. PMID: 39863950 Free article.

High serum FGF23 levels were associated with COVID-19-related mortality; Klotho levels were lower (p = 0.028). Vitamin D was not significantly different between the groups. CONCLUSION: Elevated serum FGF23 and parathyroid hormone (PTH), and lower Kloth …

High serum FGF23 levels were associated with COVID-19-related mortality; Klotho levels were lower (p = 0.028). Vitamin …

148

Vitamin D: Evidence-Based Health Benefits and Recommendations for Population Guidelines.

Grant WB, Wimalawansa SJ, Pludowski P, Cheng RZ. Grant WB, et al. Nutrients. 2025 Jan 14;17(2):277. doi: 10.3390/nu17020277. Nutrients. 2025. PMID: 39861407 Free PMC article. Review.

Vitamin D offers numerous under-recognized health benefits beyond its well-known role in musculoskeletal health. ...This is achievable through daily supplementation with 2000 IU/day (50 mcg/day) of vitamin D(3), which prevent diseases and deaths. Furth …

Vitamin D offers numerous under-recognized health benefits beyond its well-known role in musculoskeletal health. ...This is ac …

149

Herbal and Dietary Supplements as Adjunctive Treatment for Mild SARS-CoV-2 Infection in Italy.

Licata A, Seidita A, Como S, de Carlo G, Cammilleri M, Bonica R, Soresi M, Veronese N, Chianetta R, Citarrella R, Giannitrapani L, Barbagallo M. Licata A, et al. Nutrients. 2025 Jan 9;17(2):230. doi: 10.3390/nu17020230. Nutrients. 2025. PMID: 39861359 Free PMC article. Review.

During the COVID-19 pandemic, several observational studies proved a certain efficacy of nutraceuticals, herbal products, and other dietary supplements as adjuvant therapies used alongside antiviral drugs. ...Obviously, dietary supplements and herbal products do not …

During the COVID-19 pandemic, several observational studies proved a certain efficacy of nutraceuticals, herbal products, and …

150

Immune-Boosting and Antiviral Effects of Antioxidants in COVID-19 Pneumonia: A Therapeutic Perspective.

Sanduzzi Zamparelli S, Sanduzzi Zamparelli A, Bocchino M. Sanduzzi Zamparelli S, et al. Life (Basel). 2025 Jan 16;15(1):113. doi: 10.3390/life15010113. Life (Basel). 2025. PMID: 39860053 Free PMC article. Review.

The COVID-19 pandemic caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) has profoundly impacted global health, with pneumonia emerging as a major complication in severe cases. ...Antioxidants have garnered considerable attention for their potent …

The COVID-19 pandemic caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) has profoundly impacted global he …

151

Combined oral supplementation with magnesium plus vitamin D alleviates mild to moderate depressive symptoms related to long-COVID: an open-label randomized, controlled clinical trial.

Rodríguez-Morán M, Guerrero-Romero F, Barragán-Zuñiga J, Gamboa-Gómez CI, Weyman-Vela Y, Arce-Quiñones M, Simental-Mendía LE, Martínez-Aguilar G. Rodríguez-Morán M, et al. Magnes Res. 2024 décembre 01;37(3):49-57. doi: 10.1684/mrh.2024.0535. Magnes Res. 2024. PMID: 39846976 Clinical Trial.

Participants were randomly allocated into an intervention group (n=30) that received magnesium chloride (1300 mg) plus vitamin D (4000 IU), or a control group (n=30) that received vitamin D (4000 IU), for four months. ...Our results show that, among pa …

Participants were randomly allocated into an intervention group (n=30) that received magnesium chloride (1300 mg) plus vitamin D …

152

A narrative review focusing on randomized clinical trials of vitamin D supplementation for COVID-19 disease.

Huang L, Song Z, Lu C, Wang S, Guo C, Lai XH, Zhao Z. Huang L, et al. Front Nutr. 2025 Jan 7;11:1461485. doi: 10.3389/fnut.2024.1461485. eCollection 2024. Front Nutr. 2025. PMID: 39839285 Free PMC article. Review.

Current evidence is inconsistent on whether vitamin D supplementation can prevent COVID-19 infection or improve its clinical outcomes. To better understand and look into the issue, we went through the background knowledge of COVID-19 and …

Current evidence is inconsistent on whether vitamin D supplementation can prevent COVID-19 infection or improve …

153

Investigation of the rs7041 variable of vitamin D-connector protein gene relation with pancreatic involvement in patients with coronavirus disease 2019.

Öztürk V, Gül MA, Aci R, Keskin Â, Tozcu D, Cihangiroğlu M, Kaya MT, Çapraz M, Yiğit S, Tekcan A. Öztürk V, et al. Rev Assoc Med Bras (1992). 2025 Jan 10;71(1):e20241191. doi: 10.1590/1806-9282.20241191. eCollection 2025. Rev Assoc Med Bras (1992). 2025. PMID: 39813444 Free PMC article.

OBJECTIVE: This study aims to examine whether the presence of mutation exists in the vitamin D-connector protein gene rs7041 variant of the pancreatitis table for patients diagnosed with coronavirus disease 2019. ...The rs7041 genotyping of the 11th single nucleotid …

OBJECTIVE: This study aims to examine whether the presence of mutation exists in the vitamin D-connector protein gene rs7041 v …

154

Vitamin D, acute respiratory infections, and Covid-19: The curse of small-size randomised trials. A critical review with meta-analysis of randomised trials.

Autier P, Doi G, Mullie P, Vankrunkelsven P, D'Ecclesiis O, Gandini S. Autier P, et al. PLoS One. 2025 Jan 14;20(1):e0303316. doi: 10.1371/journal.pone.0303316. eCollection 2025. PLoS One. 2025. PMID: 39808630 Free PMC article.

BACKGROUND: Randomised trials conducted from 2006 to 2021 indicated that vitamin D supplementation (VDS) was able to prevent severe COVID-19 and acute respiratory infections (ARI). However, larger randomised trials published in 2022 did not confirm the …

BACKGROUND: Randomised trials conducted from 2006 to 2021 indicated that vitamin D supplementation (VDS) was able to prevent s …

155

Vitamin D supplementation to reduce maternal adverse events: the jury is still out.

Martineau AR, Iliodromiti S. Martineau AR, et al. Evid Based Nurs. 2025 Jan 11:ebnurs-2024-104058. doi: 10.1136/ebnurs-2024-104058. Online ahead of print. Evid Based Nurs. 2025. PMID: 39798949 No abstract available.

156

Klotho protein: A key modulator of aging and COVID-19 severity.

Shahzamani K, Amooyi A, Karampoor S, Khanizadeh S, Farahmand M. Shahzamani K, et al. Int J Biol Macromol. 2025 Mar;296:139234. doi: 10.1016/j.ijbiomac.2024.139234. Epub 2025 Jan 9. Int J Biol Macromol. 2025. PMID: 39798764

This study explores the relationship between Klotho, an anti-aging protein, and COVID-19 severity. Conducted at Tehran's Firouzgar Hospital, this case-control study involved 279 participants, assessing serum levels of Klotho, inflammatory markers (C-reactive protein …

This study explores the relationship between Klotho, an anti-aging protein, and COVID-19 severity. Conducted at Tehran's Firou …

157

Relationship Between Vitamin D Levels with In-Hospital Complications and Morphofunctional Recovery in a Cohort of Patients After Severe COVID-19 Across Different Obesity Phenotypes.

Simón-Frapolli VJ, López-Montalbán Á, Vegas-Aguilar IM, Generoso-Piñar M, Fernández-Jiménez R, Cornejo-Pareja IM, Sánchez-García AM, Martínez-López P, Nuevo-Ortega P, Reina-Artacho C, Estecha-Foncea MA, Gómez-González AM, González-Jiménez MB, Avanesi-Molina E, Tinahones-Madueño FJ, García-Almeida JM. Simón-Frapolli VJ, et al. Nutrients. 2024 Dec 30;17(1):110. doi: 10.3390/nu17010110. Nutrients. 2024. PMID: 39796549 Free PMC article.

RESULTS: A total of 36.2% of patients exhibited vitamin D deficiency, 29.8% vitamin D insufficiency, and only 32.9% showed sufficient levels at hospital discharge. ...Furthermore, normal vitamin D levels at the end of the follow-up were a …

RESULTS: A total of 36.2% of patients exhibited vitamin D deficiency, 29.8% vitamin D insufficiency, and only 32 …

158

AI based medical imagery diagnosis for COVID-19 disease examination and remedy.

Aboshosha A. Aboshosha A. Sci Rep. 2025 Jan 10;15(1):1607. doi: 10.1038/s41598-024-84644-1. Sci Rep. 2025. PMID: 39794454 Free PMC article.

For COVID-19 is innate immunity more important or acquired immunity? 2. Is the COVID-19 an immunity disorder or Acute Respiratory Distress Syndrome(ARDS)? ...Is the cross mortality due to aging more dangerous than COVID-19? 4. Is COVID …

For COVID-19 is innate immunity more important or acquired immunity? 2. Is the COVID-19 an immunity disorder or …

159

Comparison of the role of vitamin D in normal organs and those affected by COVID-19.

Peramaiyan R, Anthony J, Varalakshmi S, Sekar AK, Ali EM, A AHS, Abdallah BM. Peramaiyan R, et al. Int J Med Sci. 2025 Jan 1;22(2):240-251. doi: 10.7150/ijms.103260. eCollection 2025. Int J Med Sci. 2025. PMID: 39781525 Free PMC article. Review.

The outbreak of COVID-19 has opened up new avenues for exploring the importance of vitamin D in immunity, in addition to its role in calcium absorption. Recently, vitamin D supplementation has been found to enhance T regulatory lymphocyte …

The outbreak of COVID-19 has opened up new avenues for exploring the importance of vitamin D in immunity, in add …

160

Vitamin D and COVID-19: comparative analysis with other respiratory infections and impact of comorbidities.

Constantin L, Ungurianu A, Ţârcomnicu I, Bălulescu E, Margină D. Constantin L, et al. Germs. 2024 Sep 30;14(3):232-245. doi: 10.18683/germs.2024.1435. eCollection 2024 Sep. Germs. 2024. PMID: 39776957 Free PMC article.

A borderline significantly elevated NLR was observed in patients with COVID-19 who were also vitamin D deficient, compared with the similar non-COVID-19 subgroup (p=0.05). In patients with COVID-19 and insufficient vitami …

A borderline significantly elevated NLR was observed in patients with COVID-19 who were also vitamin D deficient …

161

Incidence and Outcomes of Vertebral Compression Fracture Among Patients Infected with COVID-19.

Zhang H, Balmaceno-Criss M, Fruge AM, Massey PA, Daniels AH, Zhang AS. Zhang H, et al. J Clin Med. 2024 Dec 22;13(24):7830. doi: 10.3390/jcm13247830. J Clin Med. 2024. PMID: 39768754 Free PMC article.

The patients with COVID-19 at the time of compression fracture diagnosis had a higher rate of vitamin D deficiency (OR: 1.25) and a lower rate of routine healing (OR: 0.61). ...Conclusions: Despite lower rates of osteoporosis, patients with a concomita …

The patients with COVID-19 at the time of compression fracture diagnosis had a higher rate of vitamin D deficien …

162

Vitamin D supplementations and mortality among patients with moderate/severe COVID-19: A meta-analysis of randomized controlled trials.

Mirghani H, Begum S. Mirghani H, et al. J Res Med Sci. 2024 Nov 28;29:68. doi: 10.4103/jrms.jrms_591_23. eCollection 2024. J Res Med Sci. 2024. PMID: 39764224 Free PMC article. Review.

BACKGROUND: Vitamin D deficiency is associated with severe COVID 19 and poor outcomes. However, the role of Vitamin D supplementation on mortality is controversial. ...CONCLUSION: No association was evident between Vitamin D …

BACKGROUND: Vitamin D deficiency is associated with severe COVID 19 and poor outcomes. However, the role of V …

163

Dietary intakes, nutritional and biochemical status of 6 months to 12-year-old children before the COVID-19 pandemic era: the South East Asian Nutrition Survey II Indonesia (SEANUTS II) study in Java and Sumatera Islands, Indonesia.

Kekalih A, Chandra DN, Mirtha LT, Khouw I, Wong G, Sekartini R; SEANUTS II Indonesia Study Group. Kekalih A, et al. Public Health Nutr. 2025 Jan 7;28(1):e1. doi: 10.1017/S1368980024001654. Public Health Nutr. 2025. PMID: 39763281 Free PMC article.

Dietary intakes of energy, fibre, Ca, Fe, Zn, vitamins A, B(1), C and vitamin D below the Indonesian RDA were prevalent and observed in more than half of the children. CONCLUSION: High stunting, increasing trends of overweight/ obesity, anaemia, serum vitamin …

Dietary intakes of energy, fibre, Ca, Fe, Zn, vitamins A, B(1), C and vitamin D below the Indonesian RDA were prevalent and ob …

164

Coinfection of severe acute respiratory syndrome coronavirus 2 and polyomavirus in a patient with coronavirus disease 2019 detected by enrichment next-generation sequencing: a case report.

Gunadi, Geometri ET, Adhityo P, Abidin AZ, Marcellus, Puspitarani DA, Utami FDT, Iskandar K, Wibawa H, Hakim MS. Gunadi, et al. J Med Case Rep. 2024 Dec 31;18(1):646. doi: 10.1186/s13256-024-05005-0. J Med Case Rep. 2024. PMID: 39741335 Free PMC article.

The patient was given acetaminophen, vitamin C, vitamin D, and zinc for the treatment and discharged uneventfully from the hospital 4 days after admission. ...

The patient was given acetaminophen, vitamin C, vitamin D, and zinc for the treatment and discharged uneventfully from the hos …

165

Author Correction: Randomized trial of influence of vitamin D on the prevention and improvement of symptomatic COVID-19.

Wang H, Tao L, Cui L, Chen Y, Liu D, Xue L, Yang Y, Lv Y, Zhang F, Wang T, Wang X, Yuan W, Liu H, Huang J, Jiang Y, Liu N, Yang L, Hu Y, Li Y, Gao Y, Li H, Li B, Song C. Wang H, et al. Sci Rep. 2024 Dec 31;14(1):32158. doi: 10.1038/s41598-024-83804-7. Sci Rep. 2024. PMID: 39741171 Free PMC article. No abstract available.

166

Assessment of Serum Levels of Vitamin D and Selected Biochemical and Hematological Parameters in Rats Post-Immunized with Inactivated COVID-19 Virus.

Mehravaran M, Ahmadi Hamedani M, Kafshdouzan K, Staji H, Yousefi MH. Mehravaran M, et al. Arch Razi Inst. 2024 Jun 30;79(3):609-616. doi: 10.32592/ARI.2024.79.3.609. eCollection 2024 Jun. Arch Razi Inst. 2024. PMID: 39736957 Free PMC article.

Serum levels of vitamin D (VD) are inversely correlated with the incidence or severity of COVID-19. This study aimed to investigate the effects of inactivated COVID-19 virus (ICoV-19) immunization on VD levels, as well as biochemical and …

Serum levels of vitamin D (VD) are inversely correlated with the incidence or severity of COVID-19. This study a …

167

An Observational Study on the Analysis of Vitamin D Deficiency in COVID-19 Patients With No Comorbidities: A Retrospective Analysis.

Gaba M, Vishnoi R, Kumar N, Medam AKR, Suseel S, Pandey A, Dewan A. Gaba M, et al. Cureus. 2024 Nov 29;16(11):e74737. doi: 10.7759/cureus.74737. eCollection 2024 Nov. Cureus. 2024. PMID: 39735049 Free PMC article.

INTRODUCTION: Vitamin D deficiency is an important problem when facing a viral disease. Vitamin D deficiency is widely prevalent in India and plays an important role in immunoregulation. The deficiency can lead to severe viral infections. AIMS AND OBJE …

INTRODUCTION: Vitamin D deficiency is an important problem when facing a viral disease. Vitamin D deficiency is …

168

Vitamin D Therapy May Induce Lipoma Involution: A Multi-case Report.

Martin L, Lambert R, Hoadley S, Shadman L, Lee RC. Martin L, et al. Cureus. 2024 Nov 25;16(11):e74412. doi: 10.7759/cureus.74412. eCollection 2024 Nov. Cureus. 2024. PMID: 39723312 Free PMC article.

Benign lipomas are a common medical problem that is not known to regress spontaneously. In addition, vitamin D (VD) is a known regulator of adipocyte proliferation and differentiation. Thus, the purpose of this multi-case study was to determine if optimizing serum 1 …

Benign lipomas are a common medical problem that is not known to regress spontaneously. In addition, vitamin D (VD) is a known …

169

Impact of vitamin D on COVID-19 and other viral diseases.

Nagoba BS, Gavkare AM, Rayate AS, Nanaware N, Bhavthankar S. Nagoba BS, et al. World J Virol. 2024 Dec 25;13(4):100356. doi: 10.5501/wjv.v13.i4.100356. World J Virol. 2024. PMID: 39722759 Free PMC article.

Vitamin D receptors are present in immunocompetent cells, which indicates that vitamin D can potentially modulate innate and adaptive immune responses. ...Many studies have suggested that adequate vitamin D levels help alleviate morbidity …

Vitamin D receptors are present in immunocompetent cells, which indicates that vitamin D can potentially modulat …

170

Scurvy incidence trend among children hospitalised in France, 2015-2023: a population-based interrupted time-series analysis.

Assad Z, Trad M, Valtuille Z, Dumaine C, Faye A, Ikowsky T, Kaguelidou F, Osei L, Ouldali N, Meinzer U. Assad Z, et al. Lancet Reg Health Eur. 2024 Dec 6;49:101159. doi: 10.1016/j.lanepe.2024.101159. eCollection 2025 Feb. Lancet Reg Health Eur. 2024. PMID: 39720096 Free PMC article.

Limited data exist on scurvy trends among European children, particularly following socioeconomic changes since the COVID-19 pandemic. This study analysed scurvy incidence trends among French children over a nine-year period, examining potential post-pandemic increa …

Limited data exist on scurvy trends among European children, particularly following socioeconomic changes since the COVID-19 p …

171

COVID-19 Serostatus Does Not Affect the Intrauterine Transfer of Micronutrients and Fatty Acids or Maternal-Fetal Lymphocyte Cell Composition: An Observational Study.

Surekha MV, Meur G, Suneetha N, Balakrishna N, Kumar PU, Tulja B, Reddy KS, Ibrahim A, Sunitha P. Surekha MV, et al. Am J Perinatol. 2025 Jul;42(9):1213-1222. doi: 10.1055/a-2480-5329. Epub 2024 Dec 24. Am J Perinatol. 2025. PMID: 39719143

COVID-19 did not impede essential fatty acids transfer through cord blood.. . COVID-19 affected maternal-fetal immune responses.. . COVID-19 affected vitB12, vitamin D and adrenic acid levels.....

COVID-19 did not impede essential fatty acids transfer through cord blood.. . COVID-19 affected maternal-fetal i …

172

Associations of vitamin D levels and clinical parameters with COVID-19 infection, severity and mortality in hemodialysis patients: A cohort study.

You Y, Xu C, Hu Y, Liang M, Sun Q. You Y, et al. Hemodial Int. 2025 Jan;29(1):63-73. doi: 10.1111/hdi.13194. Epub 2024 Dec 22. Hemodial Int. 2025. PMID: 39711121

COVID-19 infection status, severity, and outcomes were recorded. Statistical analyses were performed to assess the associations between vitamin D levels and COVID-19 severity and mortality. ...DISCUSSION: Vitamin D deficienc …

COVID-19 infection status, severity, and outcomes were recorded. Statistical analyses were performed to assess the association …

173

Three-year Seroprevalence of SARS-CoV-2 Nucleocapsid Protein Antibody Among Children, Parental Awareness, and Contributors of Infection: A Single-school Cohort Study in Chiba, Japan.

Yamamoto M, Sakurai K, Takatani R, Hisada A, Mori C. Yamamoto M, et al. J Epidemiol. 2025 Jun 5;35(6):278-286. doi: 10.2188/jea.JE20240284. Epub 2025 Feb 28. J Epidemiol. 2025. PMID: 39710421 Free PMC article.

BACKGROUND: Coronavirus disease 2019 (COVID-19) in children is often asymptomatic, posing challenges in detecting infections. ...These data provide useful information for developing countermeasures against COVID-19 and other future pandemics....

BACKGROUND: Coronavirus disease 2019 (COVID-19) in children is often asymptomatic, posing challenges in detecting infections. …

174

Cardiac findings in a phase II double-blind randomized placebo-controlled trial of combination therapy (HAZDPac) to treat COVID-19 patients.

Hazan S, Vidal AC, Hulscher N, Goudzwaard A, McCullough PA, Steinberg AA. Hazan S, et al. BMC Cardiovasc Disord. 2024 Dec 19;24(1):710. doi: 10.1186/s12872-024-04376-y. BMC Cardiovasc Disord. 2024. Retraction in: BMC Cardiovasc Disord. 2025 Feb 18;25(1):112. doi: 10.1186/s12872-025-04554-6. PMID: 39702045 Free PMC article. Retracted. Clinical Trial.

OBJECTIVE: Hydroxychloroquine paired with Azithromycin, Vitamin C, Vitamin D, and Zinc (HAZDPac), was used as a multidrug therapy method to treat COVID-19 illness and superimposed secondary bacterial pneumonia. ...DESIGN: We evaluated cardiac safety in …

OBJECTIVE: Hydroxychloroquine paired with Azithromycin, Vitamin C, Vitamin D, and Zinc (HAZDPac), was used as a multidrug ther …

175

The Immunomodulatory Effects of Vitamin D on COVID-19 Induced Glioblastoma Recurrence via the PI3K-AKT Signaling Pathway.

Zhang BT, Leung PC, Wong CK, Wang DJ. Zhang BT, et al. Int J Mol Sci. 2024 Dec 2;25(23):12952. doi: 10.3390/ijms252312952. Int J Mol Sci. 2024. PMID: 39684661 Free PMC article.

This study explored the molecular interactions between glioma and COVID-19 using integrated bioinformatics methods, including enrichment analysis, survival analysis, and molecular docking, focusing on the PI3K-Akt signaling pathway and the immunomodulatory role of …

This study explored the molecular interactions between glioma and COVID-19 using integrated bioinformatics methods, including …

176

Nutrient Supplements for Young Children and Mothers' Self Medication with Over-the-Counter Drugs During the COVID-19 Pandemic.

Aydın Aksoy E, Güçiz Doğan B, Yalçın SS. Aydın Aksoy E, et al. Nutrients. 2024 Dec 2;16(23):4182. doi: 10.3390/nu16234182. Nutrients. 2024. PMID: 39683575 Free PMC article.

BACKGROUND: The restriction of access to health services during the COVID-19 pandemic has led to an increase in self-medication. This study aims to examine mothers' use of nutrient supplements with over-the-counter (OTC) medications for their children, including ins …

BACKGROUND: The restriction of access to health services during the COVID-19 pandemic has led to an increase in self-medicatio …

177

Evaluation the level of vitamin D and its relationship with clinical symptoms in patients with COVID-19 referred to the medical center in Bam city.

Mortazavi SM, Khoshnood S, Faraji R, Baravati RB, Khalili H, Radfar A, Jalali E, Nezam Nia M, Akrami S, Shirani M. Mortazavi SM, et al. GMS Hyg Infect Control. 2024 Nov 5;19:Doc57. doi: 10.3205/dgkh000512. eCollection 2024. GMS Hyg Infect Control. 2024. PMID: 39669534 Free PMC article.

BACKGROUND: Vitamin D is a steroid hormone that protects against viral infections by influencing innate and adaptive immune responses. The effectiveness of vitamin D3 supplementation in COVID-19 is unknown. The study's goal was to elucidate the relatio …

BACKGROUND: Vitamin D is a steroid hormone that protects against viral infections by influencing innate and adaptive immune re …

178

Therapeutic Strategies for Tuberculosis: Progress and Lessons Learned.

Sun Q, Li S, Gao M, Pang Y. Sun Q, et al. Biomed Environ Sci. 2024 Nov 20;37(11):1310-1323. doi: 10.3967/bes2024.168. Biomed Environ Sci. 2024. PMID: 39667968 Free article. Review.

Tuberculosis (TB) remains a significant global health challenge, ranking second only to COVID-19 as the leading cause of death from a single infectious agent, with 1.3 million TB-related deaths reported in 2022. ...Immunotherapy is emerging as a complementary strate …

Tuberculosis (TB) remains a significant global health challenge, ranking second only to COVID-19 as the leading cause of death …

179

The impact of genetic polymorphism on course and severity of the SARS-CoV-2 infection and COVID-19 disease.

Wojciulik D, Wasilewska-Chrzanowska AJ, Kamiński KA, Moniuszko-Malinowska A. Wojciulik D, et al. Przegl Epidemiol. 2024 Dec 10;78(3):333-344. doi: 10.32394/pe/194862. Epub 2024 Oct 31. Przegl Epidemiol. 2024. PMID: 39660715 Review. English, Polish.

Knowledge about interactions between the virus and human proteins as well as knowledge of immunological mechanisms against infection is a key to identifying the area of virus activity and severity factors of COVID-19. Multiple variants of genes encoding proteins inv …

Knowledge about interactions between the virus and human proteins as well as knowledge of immunological mechanisms against infection is a ke …

180

Fetal death: Expert consensus of the French College of Obstetricians and Gynecologists.

Garabedian C, Sibiude J, Anselem O, Attie-Bittach T, Bertholdt C, Blanc J, Dap M, de Mézerac I, Fischer C, Girault A, Guerby P, Le Gouez A, Madar H, Quibel T, Tardy V, Stirnemann J, Vialard F, Vivanti A, Sananès N, Verspyck E. Garabedian C, et al. Int J Gynaecol Obstet. 2025 Mar;168(3):999-1008. doi: 10.1002/ijgo.16079. Epub 2024 Dec 10. Int J Gynaecol Obstet. 2025. PMID: 39655884 Free PMC article.

Regarding prevention of fetal death in the general population, it is not recommended to counsel or prescribe rest, aspirin, vitamin A, vitamin D, or micronutrient supplementation; systematically look for nuchal cord during prenatal screening ultrasound; or perform s …

Regarding prevention of fetal death in the general population, it is not recommended to counsel or prescribe rest, aspirin, vitamin A, vi …

181

Vitamin D deficiency and duration of COVID-19 symptoms in UK healthcare workers.

Chadda KR, Roberts SA, Lugg ST, Faniyi AA, Faustini SE, Webster C, Duffy JE, Hewison M, Shields A, Richter AG, Parekh D, Scott A, Thickett DR. Chadda KR, et al. Front Med (Lausanne). 2024 Nov 25;11:1494129. doi: 10.3389/fmed.2024.1494129. eCollection 2024. Front Med (Lausanne). 2024. PMID: 39655234 Free PMC article.

VD deficiency (VDD) may increase COVID-19 infection susceptibility, however research is limited on the association between VDD and COVID-19 symptom prevalence and duration. ...CONCLUSION: VDD is a significant independent risk factor for extended durati …

VD deficiency (VDD) may increase COVID-19 infection susceptibility, however research is limited on the association between VDD …

182

Correlation between rs7041 and rs4588 polymorphisms in vitamin D binding protein gene and COVID-19-related severity and mortality.

Hamed ER, Abdelhady SA, Al-Touny SA, Kishk RM, Mohamed MH, Rageh F, Othman AAA, Abdelfatah W, Azab H. Hamed ER, et al. BMC Med Genomics. 2024 Dec 2;17(1):284. doi: 10.1186/s12920-024-02018-y. BMC Med Genomics. 2024. PMID: 39623417 Free PMC article.

RESULTS: The study found that both groups had vitamin D deficiency, which was considerably lower in the COVID-19 patients group compared to controls. Among COVID-19 patients, there was a significant difference in vitamin D l …

RESULTS: The study found that both groups had vitamin D deficiency, which was considerably lower in the COVID-19 …

183

Decreased levels of vitamin D in Post-Corona Virus-19 Disease syndrome (PCS) patients compared to a control group.

Bräunlich J, Dinse-Lambracht A. Bräunlich J, et al. Clin Nutr ESPEN. 2025 Feb;65:246-248. doi: 10.1016/j.clnesp.2024.11.023. Epub 2024 Nov 29. Clin Nutr ESPEN. 2025. PMID: 39617141

BACKGROUND & AIMS: Vitamin D deficiency is defined by most experts as a level of less than 20 ng/ml. Studies have shown a relationship between musculoskeletal pain, muscle weakness, headache, and fatigue with low vitamin D level. ...These similarit …

BACKGROUND & AIMS: Vitamin D deficiency is defined by most experts as a level of less than 20 ng/ml. Studies have shown a …

184

The Effect of Vitamin D Supplementation Post COVID-19 Infection and Related Outcomes: A Systematic Review and Meta-Analysis.

Sartini M, Del Puente F, Carbone A, Schinca E, Ottria G, Dupont C, Piccinini C, Oliva M, Cristina ML. Sartini M, et al. Nutrients. 2024 Nov 5;16(22):3794. doi: 10.3390/nu16223794. Nutrients. 2024. PMID: 39599582 Free PMC article.

BACKGROUND: Vitamin D's role in COVID-19 management remains controversial. This meta-analysis aimed to evaluate the efficacy of vitamin D supplementation in patients with SARS-CoV-2 infection, focusing on mortality, intensive care unit (I …

BACKGROUND: Vitamin D's role in COVID-19 management remains controversial. This meta-analysis aimed to evaluate …

185

COVID-19 in Children and Vitamin D.

Durá-Travé T, Gallinas-Victoriano F. Durá-Travé T, et al. Int J Mol Sci. 2024 Nov 14;25(22):12205. doi: 10.3390/ijms252212205. Int J Mol Sci. 2024. PMID: 39596272 Free PMC article. Review.

Vitamin D and its links to both COVID-19 (low levels of vitamin D appear to worsen COVID-19 outcomes) and the cytokine storm (anti-inflammatory activity) are detailed. Finally, the efficacy of vitamin D supplem …

Vitamin D and its links to both COVID-19 (low levels of vitamin D appear to worsen COVID- …

186

Importance of Return to Usual and School Activities After Social Isolation in Recovering Vitamin D Concentrations, Physical Fitness, and Motor Performance in Adolescents.

Moraes FB Jr, Tadiotto MC, Lenardt B, Mota J, Matos O, Leite N. Moraes FB Jr, et al. Int J Environ Res Public Health. 2024 Nov 10;21(11):1494. doi: 10.3390/ijerph21111494. Int J Environ Res Public Health. 2024. PMID: 39595761 Free PMC article.

This study aimed to observe adolescents' changes and individual responses regarding the anthropometry, cardiometabolic profile, vitamin D concentrations, physical fitness, and motor competence upon immediate return and three months of school activities after lockdow …

This study aimed to observe adolescents' changes and individual responses regarding the anthropometry, cardiometabolic profile, vitamin …

187

COVID-19 affects vitamin D metabolism in the kidney.

Ferreira J. Ferreira J. Lab Anim (NY). 2024 Dec;53(12):355. doi: 10.1038/s41684-024-01481-5. Lab Anim (NY). 2024. PMID: 39592872 No abstract available.

188

Short-Term Outcomes in Patients With Coexistence of COVID-19 Infection and Vitamin D Deficiency: A Large Cohort Study.

Chan YJ, Chen CC, Wu JY. Chan YJ, et al. Cureus. 2024 Oct 20;16(10):e71952. doi: 10.7759/cureus.71952. eCollection 2024 Oct. Cureus. 2024. PMID: 39564063 Free PMC article.

INTRODUCTION: Vitamin D deficiency (VDD) is prevalent worldwide and may influence the severity of infectious diseases, including COVID-19. ...These findings underscore the potential importance of assessing and managing vitamin D deficienc …

INTRODUCTION: Vitamin D deficiency (VDD) is prevalent worldwide and may influence the severity of infectious diseases, includi …

189

[Long-term and seasonal dynamics of vitamin D supply indicators for the population of the Western Siberia region].

Vilms EA, Turchaninov DV, Menshchikova YV, Dobrovolskaya EV, Storozhenko AV. Vilms EA, et al. Vopr Pitan. 2024;93(5):57-64. doi: 10.33029/0042-8833-2024-93-5-57-64. Epub 2024 Sep 16. Vopr Pitan. 2024. PMID: 39563149 Russian.

Despite the active study of vitamin D, today the problem of its insufficient supply remains relevant both in Russia and throughout the world. ...Material and methods. An analysis of the vitamin D status in the residents of Western Siberia, located at 5 …

Despite the active study of vitamin D, today the problem of its insufficient supply remains relevant both in Russia and throug …

190

Vitamin D concentration in maternal serum during pregnancy: Assessment in Hokkaido in adjunct study of the Japan Environment and Children's Study (JECS).

Nakanishi K, Mutoh M, Itoh S, Kobayashi S, Yamaguchi T, Iwata H, Tamura N, Koishi M, Kasai M, Kikuchi E, Yasuura N, Kishi R, Sato Y. Nakanishi K, et al. PLoS One. 2024 Nov 15;19(11):e0312516. doi: 10.1371/journal.pone.0312516. eCollection 2024. PLoS One. 2024. PMID: 39546451 Free PMC article.

BACKGROUND: Vitamin D is an essential nutrient for maintaining blood calcium and phosphorus levels and controlling bone density. ...CONCLUSION: It was found that almost all pregnant women in Hokkaido were deficient in vitamin D. It is necessary to impl …

BACKGROUND: Vitamin D is an essential nutrient for maintaining blood calcium and phosphorus levels and controlling bone densit …

191

Dietary changes during the COVID-19 lockdown in Iranian households: are we witnessing a secular trend? A narrative review.

Nikooyeh B, Ghodsi D, Amini M, Rabiei S, Rasekhi H, Motlagh ME, Neyestani TR. Nikooyeh B, et al. Front Public Health. 2024 Oct 25;12:1485423. doi: 10.3389/fpubh.2024.1485423. eCollection 2024. Front Public Health. 2024. PMID: 39525458 Free PMC article. Review.

BACKGROUND: The COVID-19 pandemic, which emerged in late 2019, influenced nearly all aspects of human life, including food choices and dietary habits. ...Meanwhile, the use of dietary supplements, especially vitamin D, vitamin C, zinc, and multivitamin …

BACKGROUND: The COVID-19 pandemic, which emerged in late 2019, influenced nearly all aspects of human life, including food cho …

192

Calcitriol prevents SARS-CoV spike-induced inflammation in human trophoblasts through downregulating ACE2 and TMPRSS2 expression.

Vargas-Castro R, García-Quiroz J, Olmos-Ortiz A, Avila E, Larrea F, Díaz L. Vargas-Castro R, et al. J Steroid Biochem Mol Biol. 2025 Jan;245:106625. doi: 10.1016/j.jsbmb.2024.106625. Epub 2024 Nov 6. J Steroid Biochem Mol Biol. 2025. PMID: 39515592

SARS-CoV-2, the causative virus of COVID-19, increases the risk of pregnancy complications including hypertensive disorders and placental inflammation. ...Noteworthy, an ACE1/ACE2 ratio imbalance can lead to RAS dysregulation and a bad prognosis in COVID-1 …

SARS-CoV-2, the causative virus of COVID-19, increases the risk of pregnancy complications including hypertensive disorders an …

193

Clinical and Epidemiological Features of Pediatric COVID-19: A Retrospective Study.

Mirkarimi M, Heidari S, Shamsizadeh A, Tahouri K, Alisamir M, Fathi M, Mohammadi S. Mirkarimi M, et al. Health Sci Rep. 2024 Nov 6;7(11):e70181. doi: 10.1002/hsr2.70181. eCollection 2024 Nov. Health Sci Rep. 2024. PMID: 39512246 Free PMC article.

A significant proportion of children who were underweight and stunted experienced moderate to severe COVID-19. Furthermore, there was a considerably higher prevalence of malnutrition, anemia, and vitamin D insufficiency, or deficiency in children with …

A significant proportion of children who were underweight and stunted experienced moderate to severe COVID-19. Furthermore, th …

194

Vitamin D levels in children and adolescents are associated with coronavirus disease-2019 outcomes: A systematic review and meta-analysis.

Wang JG, Dou HH, Liang QY. Wang JG, et al. Medicine (Baltimore). 2024 Nov 1;103(44):e40245. doi: 10.1097/MD.0000000000040245. Medicine (Baltimore). 2024. PMID: 39495975 Free PMC article.

Vitamin D insufficiency was more common in children with COVID-19 than in healthy children (OR, 4.86; 95% CI: 2.56-9.26). The incidence of severe illness was higher (OR, 4.73; 95% CI: 1.39-16.11) whereas that of asymptomatic illness was lower (OR, 0.38 …

Vitamin D insufficiency was more common in children with COVID-19 than in healthy children (OR, 4.86; 95% CI: 2. …

195

The Challenge of Misleading Information: Does the Interaction between Zinc and Vitamin D Influence the Immune Response against SARS-CoV-2 in the Elderly Population?

Silva DMRR, Moura PHM, Gopalsamy RG, Silva EED, Barreto MDS, Santos RS, Jesus PC, Souza JB, Santana LADM, Guimarães AG, Borges LP. Silva DMRR, et al. Life (Basel). 2024 Oct 8;14(10):1277. doi: 10.3390/life14101277. Life (Basel). 2024. PMID: 39459577 Free PMC article.

In Brazil, there was a controversy regarding the well-known COVID-19 Kit, a standardized prescription for positive cases that contained zinc, and vitamin D, and anti-parasitic drugs. ...Serum levels of COVID-19 NAbs were assessed, along w …

In Brazil, there was a controversy regarding the well-known COVID-19 Kit, a standardized prescription for positive cases that …

196

Vitamin D Receptor-Interplay in COVID-19-Negative, -Infected, and -Vaccinated Women during Pregnancy.

Condac C, Lozneanu L, Matasariu DR, Ursache A, Bujor IE, Niță ME, Boiculese VL, Sava M, Țăroi P, Bîrluțiu V. Condac C, et al. J Clin Med. 2024 Oct 15;13(20):6140. doi: 10.3390/jcm13206140. J Clin Med. 2024. PMID: 39458089 Free PMC article.

Results: We found lower gestational age at birth, lower birth weight, and reduced placental VDR (vitamin D receptor) levels in COVID-19-positive women compared to COVID-19-vaccinated and COVID-19-negative women. Conclusions: …

Results: We found lower gestational age at birth, lower birth weight, and reduced placental VDR (vitamin D receptor) levels in …

197

An Epidemiological Perspective on New Pediatric Cases of Type 1 Diabetes and Vitamin D Deficiency in South-East Romania: A Retrospective Study.

Ursu M, Cretu-Stuparu M, Gurau G, Nitoi LC, Nechita A, Arbune M. Ursu M, et al. Children (Basel). 2024 Sep 25;11(10):1162. doi: 10.3390/children11101162. Children (Basel). 2024. PMID: 39457127 Free PMC article.

OBJECTIVES: The aim of this study is to analyze the epidemiological characteristics and the biological profile of children from the southeast of Romania who have been newly diagnosed with type 1 diabetes (T1DM) and to investigate the potential relationships between vitamin …

OBJECTIVES: The aim of this study is to analyze the epidemiological characteristics and the biological profile of children from the southeas …

198

Unveiling the Interplay-Vitamin D and ACE-2 Molecular Interactions in Mitigating Complications and Deaths from SARS-CoV-2.

Wimalawansa SJ. Wimalawansa SJ. Biology (Basel). 2024 Oct 16;13(10):831. doi: 10.3390/biology13100831. Biology (Basel). 2024. PMID: 39452140 Free PMC article. Review.

While SARS-CoV-2 reduces ACE-2 expression, vitamin D increases it, counteracting the virus's harmful effects. Vitamin D's beneficial actions are mediated through complex molecular mechanisms involving innate and adaptive immune systems. Meanwhile, v …

While SARS-CoV-2 reduces ACE-2 expression, vitamin D increases it, counteracting the virus's harmful effects. Vitamin …

199

Micronutrients, Vitamin D, and Inflammatory Biomarkers in COVID-19: A Systematic Review and Meta-analysis of Causal Inference Studies.

Alcalá-Santiago Á, Rodriguez-Barranco M, Sánchez MJ, Gil Á, García-Villanova B, Molina-Montes E. Alcalá-Santiago Á, et al. Nutr Rev. 2025 Jul 1;83(7):e1383-e1405. doi: 10.1093/nutrit/nuae152. Nutr Rev. 2025. PMID: 39449666 Free PMC article.

CONTEXT: Experimental and observational studies suggest that circulating micronutrients, including vitamin D (VD), may increase COVID-19 risk and its associated outcomes. Mendelian randomization (MR) studies provide valuable insight into the causal rel …

CONTEXT: Experimental and observational studies suggest that circulating micronutrients, including vitamin D (VD), may increas …

200

Effects of Immunotoxicity biomarkers, essential elements and vitamin D levels on the severity levels of COVID-19 disease in Turkey.

Secerlı J, Çetinkaya S, Leblebici İS, Özdemir LA, Yücel Ç, Karaismailoğlu E, Kara U, Özcan A, Öcal N, Arslan Y, Şenkal S, Erdem O, Bacanlı MG. Secerlı J, et al. Toxicol Res (Camb). 2024 Oct 20;13(5):tfae177. doi: 10.1093/toxres/tfae177. eCollection 2024 Oct. Toxicol Res (Camb). 2024. PMID: 39439527 Free PMC article.

Many mechanisms are thought to play a role in the pathogenesis of the COVID-19 pandemic, which started in 2019 and affected the whole world. It has been claimed that a deficiency in the immune system can significantly affect the severity of COVID-19 di …

Many mechanisms are thought to play a role in the pathogenesis of the COVID-19 pandemic, which started in 2019 and affected th …

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