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Page 1
Low-dose psilocybin in short-lasting unilateral neuralgiform headache attacks: results from an open-label phase Ib ascending dose study.
Rucker J, Butler M, Hambleton S, Bird C, Seynaeve M, Cheema S, Campbell-Coker K, Maggio C, Dunbar F, Lambru G, Matharu M. Rucker J, et al. Headache. 2024 Nov-Dec;64(10):1309-1317. doi: 10.1111/head.14837. Epub 2024 Sep 20. Headache. 2024. PMID: 39301810 Free PMC article. Clinical Trial.
Subjective dose intensity was assessed via the five-Dimensional Altered States of Consciousness Questionnaire (5D-ASC). The study was terminated early due to recruitment difficulties; four patients were enrolled, three of whom were study completers. Post hoc, we undertook …
Subjective dose intensity was assessed via the five-Dimensional Altered States of Consciousness Questionnaire (5D-ASC). The study was …
Mitochondrial Dysfunction Contributes to Sustained Muscle Loss After Cardiac Surgery: A Prospective Observational Study.
Thomas AN, Kalakoutas A, Yates M, Yap J, Sanders J, Kemp P, Griffiths MJD. Thomas AN, et al. J Cachexia Sarcopenia Muscle. 2025 Aug;16(4):e70051. doi: 10.1002/jcsm.70051. J Cachexia Sarcopenia Muscle. 2025. PMID: 40842041 Free PMC article.
Proportionate mean loss of RFcsa between pre-op and Day 7 values was 6.44% [95% CI 4.21 to 8.68, n = 31]; between pre-op and follow-up 9.69% [95% CI 4.92 to 14.96, n = 22]; and between Day 7 and follow-up 3.60% [95% CI -1.30 to 8.48, n = 22]. By contra …
Proportionate mean loss of RFcsa between pre-op and Day 7 values was 6.44% [95% CI 4.21 to 8.68, n = 31]; between pre-op and follow-up 9.69% …
Outcome following mini-open lower limb fasciotomy for chronic exertional compartment syndrome.
Oliver WM, Rhatigan D, Mackenzie SP, White TO, Duckworth AD, Molyneux SG. Oliver WM, et al. Eur J Orthop Surg Traumatol. 2022 Jan;32(1):27-36. doi: 10.1007/s00590-021-02919-z. Epub 2021 Mar 6. Eur J Orthop Surg Traumatol. 2022. PMID: 33675406 Free PMC article.
Patient-reported outcomes (including EuroQol scores [EQ-5D/EQ-VAS], return to sport and satisfaction) were obtained via postal survey from 27/38 respondents (71%) at a mean of 3.7 years (0.3-6.4). ...Seventy-four per cent (n = 20/27) were satisfied and 81% (n = 2
Patient-reported outcomes (including EuroQol scores [EQ-5D/EQ-VAS], return to sport and satisfaction) were obtained via postal survey …
Effect of neuromuscular control exercise program using non-elastic taping on the knee joint in patients with knee osteoarthritis.
Yoon SW, Kim SY. Yoon SW, et al. Medicine (Baltimore). 2025 Apr 25;104(17):e42173. doi: 10.1097/MD.0000000000042173. Medicine (Baltimore). 2025. PMID: 40295308 Free PMC article. Clinical Trial.
A total of 44 elderly individuals (aged 65 years) with knee osteoarthritis were randomly assigned to an experimental group (n = 22) and a control group (n = 22). Both groups underwent a neuromuscular control exercise program, with the experimental gr …
A total of 44 elderly individuals (aged 65 years) with knee osteoarthritis were randomly assigned to an experimental group (n = …
Bi-unicondylar arthroplasty : a biomechanics and clinical outcomes study.
Garner AJ, Dandridge OW, Amis AA, Cobb JP, van Arkel RJ. Garner AJ, et al. Bone Joint Res. 2021 Nov;10(11):723-733. doi: 10.1302/2046-3758.1011.BJR-2021-0151.R1. Bone Joint Res. 2021. PMID: 34761697 Free PMC article.
The aim of this study is to investigate the clinical outcomes and biomechanics of Bi-UKA. METHODS: Bi-UKA subjects (n = 22) were measured on an instrumented treadmill, using standard gait metrics, at top walking speeds. Age-, sex-, and BMI-matched healthy (n = 24) a …
The aim of this study is to investigate the clinical outcomes and biomechanics of Bi-UKA. METHODS: Bi-UKA subjects (n = 22) we …
Characteristics and Quality of Life of Patients with COPD with Different Degrees of Exercise-Induced Desaturation on Six-minute Walk Test.
Gao B, Wang S, Zhao L, Liao H, Qumu S, Wang P, Yang T, Jiang S. Gao B, et al. Int J Chron Obstruct Pulmon Dis. 2025 Jul 14;20:2381-2391. doi: 10.2147/COPD.S513089. eCollection 2025. Int J Chron Obstruct Pulmon Dis. 2025. PMID: 40688240 Free PMC article.
Patients were categorized into three groups based on oxygen desaturation (SpO(2)) during the six-minute walk test (6MWT): non-EID (n = 52), mild-EID (n = 42), and severe-EID (n = 22). EID was classified as follows: Mild EID: SpO(2) decrease 4% with nadir SpO(2) 90 …
Patients were categorized into three groups based on oxygen desaturation (SpO(2)) during the six-minute walk test (6MWT): non-EID (n = 52), …
The trend in quality of life of Chinese population: analysis based on population health surveys from 2008 to 2020.
Wang D, Xie S, Wu J, Sun B. Wang D, et al. BMC Public Health. 2023 Jan 24;23(1):167. doi: 10.1186/s12889-023-15075-2. BMC Public Health. 2023. PMID: 36694154 Free PMC article.
METHODS: Data were obtained from the 2008, 2013, and 2020 waves of the Health Services Surveys conducted in Tianjin, China. Respondents completed the EQ-5D (EQ-5D-3L in 2008 and 2013 and EQ-5D-5L in 2020) through face-to-face interviews or self-administration …
METHODS: Data were obtained from the 2008, 2013, and 2020 waves of the Health Services Surveys conducted in Tianjin, China. Respondents comp …
Completeness and Mismatch of Patient-Important Outcomes After Trauma.
James A, Ravaud P, Riveros C, Raux M, Tran VT. James A, et al. Ann Surg Open. 2022 Nov 7;3(4):e211. doi: 10.1097/AS9.0000000000000211. eCollection 2022 Dec. Ann Surg Open. 2022. PMID: 37600291 Free PMC article.
Beside mortality, measurement tools most frequently used were the Glasgow Outcome Scale (31.0%, n=36), questions on patients' return to work (20,7%, n=24) and the EQ-5D (19.0%, n=22). The comparison between the outcomes identified in the systematic review and …
Beside mortality, measurement tools most frequently used were the Glasgow Outcome Scale (31.0%, n=36), questions on patients' return to work …
Cost-Effectiveness of the Mindfulness-Based Childbirth and Parenting Program for Pregnant Women With Fear of Childbirth.
van Steensel FJA, Veringa-Skiba IK, Sauer AR, de Bruin EI, Bögels SM. van Steensel FJA, et al. J Obstet Gynecol Neonatal Nurs. 2024 Jan;53(1):57-68. doi: 10.1016/j.jogn.2023.10.004. Epub 2023 Nov 18. J Obstet Gynecol Neonatal Nurs. 2024. PMID: 37984493 Free article. Clinical Trial.
PARTICIPANTS: Subset of pregnant women with high levels of fear of childbirth (N = 54: randomized to MBCP, n = 32, or to ECAU, n = 22) who were selected from the parent study because they completed all four cost questionnaires. ...We used the Wijma Delivery Expectan …
PARTICIPANTS: Subset of pregnant women with high levels of fear of childbirth (N = 54: randomized to MBCP, n = 32, or to ECAU, n = …
Metformin Blunts Vascular Insulin Sensitivity After Exercise Training in Adults at Risk for Metabolic Syndrome.
Malin SK, Heiston EM, Battillo DJ, Ragland TJ, Gow AJ, Shapses SA, Shah AM, Patrie JT, Barrett EJ. Malin SK, et al. J Clin Endocrinol Metab. 2026 Mar 17;111(4):e1124-e1135. doi: 10.1210/clinem/dgaf551. J Clin Endocrinol Metab. 2026. PMID: 41160096 Clinical Trial.
METHODS: In a double-blind, placebo-controlled trial, participants were randomly assigned to low-intensity exercise plus placebo ( 55% VO2max 5d/wk, LoEx + PL, n = 22) or metformin (2000 mg/d, LoEx + Met, n = 21) and high-intensity exercise plus placebo ( 85% …
METHODS: In a double-blind, placebo-controlled trial, participants were randomly assigned to low-intensity exercise plus placebo ( 55% VO2ma …
57 results