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The following terms were not found in PubMed: 22Carcinoma, 2Fgenetics, 5BMeSH
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Identification of Optically Active Pyrimidine Derivatives as Selective 5-HT(2C) Modulators.
Molecules. 2017 Aug 26;22(9):1416. doi: 10.3390/molecules22091416.
Molecules. 2017.
PMID: 28846591
Free PMC article.
A series of pyrimidine derivatives 4a-i were synthesized and evaluated for their binding affinities towards 5-HT(2C) receptors. With regard to designed molecules 4a-i, the influence of the size of alkyl ether and the absolute configuration of a stereogenic center on the 5- …
A series of pyrimidine derivatives 4a-i were synthesized and evaluated for their binding affinities towards 5-HT(2C) receptors. With …
Postjunctional alpha(2C)-adrenoceptor contractility in human saphenous vein.
Rizzo CA, Ruck LM, Corboz MR, Umland SP, Wan Y, Shah H, Jakway J, Cheng L, McCormick K, Egan RW, Hey JA.
Rizzo CA, et al.
Eur J Pharmacol. 2001 Feb 16;413(2-3):263-9. doi: 10.1016/s0014-2999(01)00772-5.
Eur J Pharmacol. 2001.
PMID: 11226402
The alpha(2)-adrenoceptor subtype affinities (pK(i)) obtained in recombinant human alpha(2A)-, alpha(2B)- and alpha(2C)-adrenoceptor competition binding assays were 8.6, 8.3 and 8.6 for yohimbine; 6.3, 8.4 and 7.0 for ARC 239; 8.4, 7.5 and 8.4 for WB 4101 and 7.5, 7.4 and …
The alpha(2)-adrenoceptor subtype affinities (pK(i)) obtained in recombinant human alpha(2A)-, alpha(2B)- and alpha(2C)-adrenoceptor …
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Thieno[3,2-c]pyran-4-one based novel small molecules: their synthesis, crystal structure analysis and in vitro evaluation as potential anticancer agents.
Nakhi A, Adepu R, Rambabu D, Kishore R, Vanaja GR, Kalle AM, Pal M.
Nakhi A, et al.
Bioorg Med Chem Lett. 2012 Jul 1;22(13):4418-27. doi: 10.1016/j.bmcl.2012.04.109. Epub 2012 May 2.
Bioorg Med Chem Lett. 2012.
PMID: 22632935
Some of the compounds synthesized showed selective growth inhibition of cancer cells in vitro among which two compounds for example, 5d and 6c showed IC(50) values in the range of 2.0-2.5 muM. ...
Some of the compounds synthesized showed selective growth inhibition of cancer cells in vitro among which two compounds for example, …
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