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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1786 1
1790 2
1800 22
1805 4
1806 4
1807 1
1808 1
1809 102
1810 15
1813 5
1814 2
1816 1
1817 6
1821 1
1824 28
1828 14
1829 61
1832 1
1835 38
1837 1
1838 7
1839 30
1840 6
1841 40
1842 11
1843 10
1844 27
1845 6
1846 74
1847 12
1848 9
1849 8
1850 13
1851 14
1852 7
1853 41
1854 3
1855 2
1856 3
1857 4
1858 58
1859 1
1860 4
1861 6
1862 5
1863 3
1864 4
1865 131
1866 2
1867 5
1868 147
1869 5
1870 3
1871 3
1872 12
1873 14
1874 13
1875 376
1876 119
1877 110
1878 4
1879 6
1880 17
1881 10
1882 73
1883 108
1884 45
1885 5
1886 3
1887 247
1888 126
1889 59
1890 14
1891 16
1892 256
1893 371
1894 10
1895 84
1896 75
1897 501
1898 36
1899 16
1900 7
1901 412
1902 10
1903 63
1904 58
1905 258
1906 104
1907 117
1908 12
1909 14
1910 44
1911 12
1912 14
1913 16
1914 16
1915 79
1916 11
1917 12
1918 18
1919 18
1920 21
1921 32
1922 14
1923 59
1924 423
1925 33
1926 30
1927 17
1928 304
1929 486
1930 374
1931 53
1932 245
1933 80
1934 52
1935 12
1936 161
1937 60
1938 115
1939 44
1940 14
1941 19
1942 9
1943 121
1944 14
1945 254
1946 1258
1947 1192
1948 907
1949 773
1950 1659
1951 2280
1952 1916
1953 1990
1954 1547
1955 1179
1956 1493
1957 1879
1958 2087
1959 1367
1960 985
1961 1633
1962 1697
1963 2310
1964 1843
1965 2418
1966 3448
1967 7549
1968 6026
1969 4922
1970 5123
1971 5263
1972 5270
1973 4678
1974 6395
1975 7154
1976 9330
1977 9616
1978 7528
1979 8492
1980 8477
1981 10064
1982 10517
1983 12269
1984 12254
1985 12918
1986 13084
1987 14619
1988 15091
1989 16761
1990 20384
1991 18790
1992 22089
1993 22173
1994 23337
1995 23776
1996 25393
1997 25656
1998 26535
1999 28099
2000 28461
2001 33993
2002 36837
2003 37825
2004 38607
2005 42164
2006 48587
2007 51331
2008 56240
2009 54063
2010 61467
2011 68004
2012 73306
2013 74531
2014 80164
2015 85740
2016 89990
2017 85077
2018 88455
2019 92473
2020 116878
2021 142625
2022 151852
2023 116486
2024 32083
2025 1

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2,077,967 results

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Page 1
Role of IL-22 in homeostasis and diseases of the skin.
Lopez DV, Kongsbak-Wismann M. Lopez DV, et al. APMIS. 2022 Jun;130(6):314-322. doi: 10.1111/apm.13221. Epub 2022 Apr 6. APMIS. 2022. PMID: 35316548 Free PMC article. Review.
Interleukin-22 (IL-22) is a cytokine mainly produced by T cells and innate lymphoid cells (ILC). ...In this review, current information regarding the structure, function and regulation of IL-22 is discussed with a special focus on the role of IL-22 in …
Interleukin-22 (IL-22) is a cytokine mainly produced by T cells and innate lymphoid cells (ILC). ...In this review, current in …
Interleukin-22 Influences the Th1/Th17 Axis.
Lindahl H, Olsson T. Lindahl H, et al. Front Immunol. 2021 Feb 22;12:618110. doi: 10.3389/fimmu.2021.618110. eCollection 2021. Front Immunol. 2021. PMID: 33692792 Free PMC article. Review.
Interleukin-22 (IL-22) is secreted by a wide range of immune cells and its downstream effects are mediated by the IL-22 receptor, which is present on non-immune cells in many organs throughout the body. ...We have reviewed the literature for experimental data …
Interleukin-22 (IL-22) is secreted by a wide range of immune cells and its downstream effects are mediated by the IL-22
Interleukin-22 acts as a mitochondrial protector.
Hwang S, Feng D, Gao B. Hwang S, et al. Theranostics. 2020 Jun 19;10(17):7836-7840. doi: 10.7150/thno.48022. eCollection 2020. Theranostics. 2020. PMID: 32685023 Free PMC article.
Interleukin (IL)-22 has been increasingly recognized as a promising therapeutic option for various types of diseases. This commentary summarizes the novel mechanistic aspects of IL-22 for the treatment of liver diseases including the study by Chen et al. published i …
Interleukin (IL)-22 has been increasingly recognized as a promising therapeutic option for various types of diseases. This commentary …
Effects of IL-22 on cardiovascular diseases.
Che Y, Su Z, Xia L. Che Y, et al. Int Immunopharmacol. 2020 Apr;81:106277. doi: 10.1016/j.intimp.2020.106277. Epub 2020 Feb 14. Int Immunopharmacol. 2020. PMID: 32062077 Review.
Interleukin-22 (IL-22), which belongs to the IL-10 family, is an alpha helix cytokine specifically produced by many lymphocytes, such as Th1, Th17, Th22, ILCs, CD4+ and CD8+ T cells. ...Here, we summarize the recent progress on the source, function, regulation of IL …
Interleukin-22 (IL-22), which belongs to the IL-10 family, is an alpha helix cytokine specifically produced by many lymphocyte …
Targeting interleukin-22 in psoriasis.
Hao JQ. Hao JQ. Inflammation. 2014 Feb;37(1):94-9. doi: 10.1007/s10753-013-9715-y. Inflammation. 2014. PMID: 23978911 Review.
Interleukin-22 (IL-22) is an IL-10 family cytokine that was recently discovered to be released by T helper 17 (Th17) cells, Th22 cells, etc. ...All these findings suggest that IL-22 may be implicated in psoriasis; therapeutics targeting IL-22 may have …
Interleukin-22 (IL-22) is an IL-10 family cytokine that was recently discovered to be released by T helper 17 (Th17) cells, Th …
miR-22 gene therapy treats HCC by promoting anti-tumor immunity and enhancing metabolism.
Hu Y, Setayesh T, Vaziri F, Wu X, Hwang ST, Chen X, Yvonne Wan YJ. Hu Y, et al. Mol Ther. 2023 Jun 7;31(6):1829-1845. doi: 10.1016/j.ymthe.2023.04.019. Epub 2023 May 4. Mol Ther. 2023. PMID: 37143325 Free article.
The tumor suppressor effects of miR-22 have been suggested, but whether miR-22 treats orthotopic hepatocellular carcinoma (HCC) is not established. ...Moreover, depleting cytotoxic T cells also abolished the anti-HCC effects of miR-22. In patients, miR-22
The tumor suppressor effects of miR-22 have been suggested, but whether miR-22 treats orthotopic hepatocellular carcinoma (HCC …
Emanuel Syndrome.
Emanuel BS, Zackai EH, Medne L. Emanuel BS, et al. 2007 Apr 20 [updated 2017 Aug 31]. In: Adam MP, Feldman J, Mirzaa GM, Pagon RA, Wallace SE, Bean LJH, Gripp KW, Amemiya A, editors. GeneReviews® [Internet]. Seattle (WA): University of Washington, Seattle; 1993–2024. 2007 Apr 20 [updated 2017 Aug 31]. In: Adam MP, Feldman J, Mirzaa GM, Pagon RA, Wallace SE, Bean LJH, Gripp KW, Amemiya A, editors. GeneReviews® [Internet]. Seattle (WA): University of Washington, Seattle; 1993–2024. PMID: 20301440 Free Books & Documents. Review.
GENETIC COUNSELING: In more than 99% of cases, one of the parents of a proband with Emanuel syndrome is a balanced carrier of a t(11;22)(q23;q11.2) and is phenotypically normal. In most cases, a carrier parent has inherited the t(11;22) from a parent. When one of th …
GENETIC COUNSELING: In more than 99% of cases, one of the parents of a proband with Emanuel syndrome is a balanced carrier of a t(11;22
Interleukin-22/Interleukin-22 binding protein axis and oral contraceptive use in polycystic ovary syndrome.
Aksun S, Ersal E, Portakal O, Yildiz BO. Aksun S, et al. Endocrine. 2023 Jul;81(1):54-57. doi: 10.1007/s12020-023-03360-4. Epub 2023 Apr 4. Endocrine. 2023. PMID: 37012532
IL-22/IL-22BP ratio was calculated in order to have a better reflection of IL-22 biological activity. ...CONCLUSIONS: Results of this study show that women with PCOS have similar circulating concentrations of IL-22 and IL-22BP with healthy women and that shor …
IL-22/IL-22BP ratio was calculated in order to have a better reflection of IL-22 biological activity. ...CONCLUSIONS: Results …
Clinical importance of IL-22 cascade in IBD.
Mizoguchi A, Yano A, Himuro H, Ezaki Y, Sadanaga T, Mizoguchi E. Mizoguchi A, et al. J Gastroenterol. 2018 Apr;53(4):465-474. doi: 10.1007/s00535-017-1401-7. Epub 2017 Oct 26. J Gastroenterol. 2018. PMID: 29075900 Free PMC article. Review.
Despite the beneficial effect of IL-22, continuous activation of the IL-22 pathway increases the risk of colitis-associated cancer, particularly in patients with an extended history of IBD. This review article discusses how IL-22 regulates colitis, how benefi …
Despite the beneficial effect of IL-22, continuous activation of the IL-22 pathway increases the risk of colitis-associated ca …
Interleukin 22 in Liver Injury, Inflammation and Cancer.
Wu Y, Min J, Ge C, Shu J, Tian D, Yuan Y, Zhou D. Wu Y, et al. Int J Biol Sci. 2020 Jun 29;16(13):2405-2413. doi: 10.7150/ijbs.38925. eCollection 2020. Int J Biol Sci. 2020. PMID: 32760208 Free PMC article. Review.
Interleukin 22(IL-22), a member of the IL-10 cytokine family and is an emerging CD4+Th cytokine that plays an important role in anti-microbial defense, homeostasis and tissue repair. ...In conclusion, the hepatoprotective functions and liver regeneration promoting e …
Interleukin 22(IL-22), a member of the IL-10 cytokine family and is an emerging CD4+Th cytokine that plays an important role i …
2,077,967 results
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