Epidemiology of hepatitis B virus infection in truck drivers in Brazil, South America

Sex Transm Infect. 2008 Oct;84(5):386-9. doi: 10.1136/sti.2008.030205. Epub 2008 Jul 24.

Abstract

Objective: To investigate the epidemiology of hepatitis B virus (HBV) infection and viral genotypes in long distance truck drivers in Brazil.

Methods: We interviewed 641 long distance truck drivers to gather data on sociodemographics and risk factors and collected blood samples to test for HBV markers (HBsAg, anti-HBs and anti-HBc) by ELISA. HBsAg-positive samples were submitted to HBV DNA detection and genotyped.

Results: We found a global HBV prevalence of 18.9% (95% CI 15.9 to 22.2). Thirty truck drivers (4.7%) had only anti-HBs, suggesting that they had a previous HBV vaccination. More than 20 years in the profession, more than 15 days away from home and a history of sexual transmitted infections were independently and positivity associated with HBV markers. HBV DNA was detected in nine samples in which genotypes A (n = 5), D (n = 2) and F (n = 2) were found.

Conclusions: These findings confirm that truck drivers are at high risk for hepatitis B infection and highlight the importance of having a public health policy that addresses this population and is based on the characteristics of HBV acquisition and dissemination.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Automobile Driving / statistics & numerical data*
  • Brazil / epidemiology
  • Female
  • Hepatitis B Surface Antigens / blood
  • Hepatitis B virus / isolation & purification
  • Hepatitis B, Chronic / epidemiology*
  • Humans
  • Male
  • Occupational Diseases / epidemiology*
  • Prevalence
  • Regression Analysis
  • Socioeconomic Factors

Substances

  • Hepatitis B Surface Antigens