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Page 1
Improvements in Patient-Reported Outcomes in Relapsed or Refractory Large B-Cell Lymphoma Patients Treated With Epcoritamab.
Phillips T, Lugtenburg P, Kalsekar A, Mutebi A, Wang A, Blaedel J, Kosa K, Martin S, Sacchi M, Kilavuz N, Thieblemont C. Phillips T, et al. Clin Lymphoma Myeloma Leuk. 2024 Mar;24(3):e78-e87.e2. doi: 10.1016/j.clml.2023.11.005. Epub 2023 Nov 27. Clin Lymphoma Myeloma Leuk. 2024. PMID: 38151388 Free article.
FACT-Lym and EQ-5D-3L score changes from baseline (CFB) to cycle 9 or end of treatment were interpreted using published minimally important differences (MID). ...FACT-Lym scores exceeded MID thresholds: mean (SD) CFB were 4.4 (15.2), MID 3.0 to 7.0 (FACT-General); 5.9 (7.6 …
FACT-Lym and EQ-5D-3L score changes from baseline (CFB) to cycle 9 or end of treatment were interpreted using published minimally imp …
Interconversion of the cis-5R,6S- and trans-5R,6R-thymine glycol lesions in duplex DNA.
Brown KL, Adams T, Jasti VP, Basu AK, Stone MP. Brown KL, et al. J Am Chem Soc. 2008 Sep 3;130(35):11701-10. doi: 10.1021/ja8016544. Epub 2008 Aug 6. J Am Chem Soc. 2008. PMID: 18681438 Free PMC article.
The 5R Tg lesion was incorporated site-specifically into 5'-d(G(1)T(2)G(3)C(4)G(5)Tg(6)G(7)T(8)T(9)T(10)G(11)T(12))-3'; Tg = 5R Tg. The Tg-modified oligodeoxynucleotide was annealed with either 5'-d(A(13)C(14)A(15)A(16)A(17)C(18)A(19)C(20)G(21)C …
The 5R Tg lesion was incorporated site-specifically into 5'-d(G(1)T(2)G(3)C(4)G(5)Tg(6)G(7)T(8)T(9)T(10)G(11)T(12))-3'; Tg …
The economic and humanistic burden of bipolar disorder in adults in the United States.
Dembek C, Mackie D, Modi K, Zhu Y, Niu X, Grinnell T. Dembek C, et al. Ann Gen Psychiatry. 2023 Mar 24;22(1):13. doi: 10.1186/s12991-023-00440-7. Ann Gen Psychiatry. 2023. PMID: 36964564 Free PMC article.
Multivariate regression models of all-cause hospitalizations in the past 6 months, annualized direct healthcare costs, annualized indirect costs, and HRQoL (eg, EuroQol 5-Dimension Health Questionnaire (EQ-5D)) controlled for confounders (demographic and clinical character …
Multivariate regression models of all-cause hospitalizations in the past 6 months, annualized direct healthcare costs, annualized indirect c …
The cis-(5R,6S)-thymine glycol lesion occupies the wobble position when mismatched with deoxyguanosine in DNA.
Brown KL, Basu AK, Stone MP. Brown KL, et al. Biochemistry. 2009 Oct 20;48(41):9722-33. doi: 10.1021/bi900695e. Biochemistry. 2009. PMID: 19772348 Free PMC article.
Oxidative damage to 5-methylcytosine in DNA, followed by deamination, yields thymine glycol (Tg), 5,6-dihydroxy-5,6-dihydrothymine, mispaired with deoxyguanosine. The structure of the 5R Tg.G mismatch pair has been refined using a combination of simulated annealing …
Oxidative damage to 5-methylcytosine in DNA, followed by deamination, yields thymine glycol (Tg), 5,6-dihydroxy-5,6-dihydrothymine, m …
Utility-Weighted Modified Rankin Scale Scores for the Assessment of Stroke Outcome: Pooled Analysis of 20 000+ Patients.
Wang X, Moullaali TJ, Li Q, Berge E, Robinson TG, Lindley R, Zheng D, Delcourt C, Arima H, Song L, Chen X, Yang J, Chalmers J, Anderson CS, Sandset EC. Wang X, et al. Stroke. 2020 Aug;51(8):2411-2417. doi: 10.1161/STROKEAHA.119.028523. Epub 2020 Jul 9. Stroke. 2020. PMID: 32640944
Linear regression models were used to validate UW-mRS scores by assessing differences in mean UW-mRS scores between the treatment groups of each trial. To explore the variability in EQ-5D between individual mRS categories, we generated receiver operator characteristic curv …
Linear regression models were used to validate UW-mRS scores by assessing differences in mean UW-mRS scores between the treatment groups of …
Longitudinal health-related quality of life in first-line treated patients with chronic lymphocytic leukemia: Results from the Connect® CLL Registry.
Sharman JP, Cocks K, Nabhan C, Lamanna N, Kay NE, Grinblatt DL, Flowers CR, Davids MS, Kiselev P, Swern AS, Sullivan K, Gharibo MM, Flick ED, Trigg A, Mato A. Sharman JP, et al. EJHaem. 2020 Jul 26;1(1):188-198. doi: 10.1002/jha2.67. eCollection 2020 Jul. EJHaem. 2020. PMID: 35847738 Free PMC article.
We assessed HRQoL using the FACT-Leu and EQ-5D-3L questionnaires in the Connect () CLL Registry, a large, US-based, multicenter, prospective observational study of CLL patients enrolled between 2010 and 2014, prior to the introduction of novel therapies. ...Among 526 patie …
We assessed HRQoL using the FACT-Leu and EQ-5D-3L questionnaires in the Connect () CLL Registry, a large, US-based, multicenter, pros …
Development of Poly(methyl methacrylate)-Based Copolymers with Improved Heat Resistance and Reduced Moisture Absorption.
Park J, Baek MJ, Choi HW, Kim HS, Lee DW. Park J, et al. Langmuir. 2019 Dec 3;35(48):15880-15886. doi: 10.1021/acs.langmuir.9b02024. Epub 2019 Aug 28. Langmuir. 2019. PMID: 31419144
All of the polymers synthesized exhibited improved heat resistance, with PMSAm-CHMI exhibiting the highest glass transition temperature (T(g) = 122.54 C) and 5% weight loss thermal decomposition temperature (T(5d) = 343.40 C) as well as the lowest thermal expansion coeffic …
All of the polymers synthesized exhibited improved heat resistance, with PMSAm-CHMI exhibiting the highest glass transition temperature (T(g …
Detection of guanine-adenine mismatches by surface plasmon resonance sensor carrying naphthyridine-azaquinolone hybrid on the surface.
Hagihara S, Kumasawa H, Goto Y, Hayashi G, Kobori A, Saito I, Nakatani K. Hagihara S, et al. Nucleic Acids Res. 2004 Jan 9;32(1):278-86. doi: 10.1093/nar/gkh171. Print 2004. Nucleic Acids Res. 2004. PMID: 14715926 Free PMC article.
In the presence of Npt-Azq, the melting temperature (T(m)) of 5'-d(CTA ACG GAA TG)-3'/3'-d(GAT TGA CTT AC)-5' containing a single G-A mismatch increased by 15.4 degrees C, whereas fully matched duplex increased its T(m) only by 2.2 degrees C. ...
In the presence of Npt-Azq, the melting temperature (T(m)) of 5'-d(CTA ACG GAA TG)-3'/3'-d(GAT TGA CTT AC)-5' containing a single G-A …
Instruments to measure outcomes of post-intensive care syndrome in outpatient care settings - Results of an expert consensus and feasibility field test.
Spies CD, Krampe H, Paul N, Denke C, Kiselev J, Piper SK, Kruppa J, Grunow JJ, Steinecke K, Gülmez T, Scholtz K, Rosseau S, Hartog C, Busse R, Caumanns J, Marschall U, Gersch M, Apfelbacher C, Weber-Carstens S, Weiss B. Spies CD, et al. J Intensive Care Soc. 2021 May;22(2):159-174. doi: 10.1177/1751143720923597. Epub 2020 May 14. J Intensive Care Soc. 2021. PMID: 34025756 Free PMC article.
First step: Screening with brief tests covering PICS domains of (1) mental health (Patient Health Questionnaire-4 (PHQ-4)), (2) cognition (MiniCog, Animal Naming), (3) physical function (Timed Up-and-Go (TUG), handgrip strength), and (4) health-related quality of life (HRQoL) (EQ …
First step: Screening with brief tests covering PICS domains of (1) mental health (Patient Health Questionnaire-4 (PHQ-4)), (2) cognition (M …
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