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Page 1
Impact of Pembrolizumab Versus Chemotherapy as Second-Line Therapy for Advanced Esophageal Cancer on Health-Related Quality of Life in KEYNOTE-181.
Adenis A, Kulkarni AS, Girotto GC, de la Fouchardiere C, Senellart H, van Laarhoven HWM, Mansoor W, Al-Rajabi R, Norquist J, Amonkar M, Suryawanshi S, Bhagia P, Metges JP. Adenis A, et al. J Clin Oncol. 2022 Feb 1;40(4):382-391. doi: 10.1200/JCO.21.00601. Epub 2021 Nov 3. J Clin Oncol. 2022. PMID: 34730989 Clinical Trial.
PATIENTS AND METHODS: HRQoL was measured using the European Organisation for Research and Treatment of Cancer (EORTC) Quality of Life Questionnaire Core 30 (QLQ-C30), EORTC QLQ EC questionnaire (OES18), and EuroQol 5-dimension questionnaire (EQ-5D). Data were analyzed in p …
PATIENTS AND METHODS: HRQoL was measured using the European Organisation for Research and Treatment of Cancer (EORTC) Quality of Life Questi …
Quality of life in SSc-ILD patients: Understanding the impact of the ILD and the needs of the SSc-ILD patients and their need for caregivers in France.
Allanore Y, Constans J, Godard D, de Pouvourville G, Bouee S, Jeanbat V, Teissier C, Le Lay K, Chollet J, Hachulla E. Allanore Y, et al. J Scleroderma Relat Disord. 2022 Feb;7(1):49-56. doi: 10.1177/23971983211013979. Epub 2021 Jun 21. J Scleroderma Relat Disord. 2022. PMID: 35386942 Free PMC article.
RESULTS: In all, 89 patients were included. 26.4% were males, mean age was 58.2 14.5 years. Mean EQ-5D-5L score = 0.79 0.22 (median = 0.85). Mean EQ-5D-5L visual analog scale score = 60.8 20.4 (median = 61.5). ...After adjustment on covariates, a significant …
RESULTS: In all, 89 patients were included. 26.4% were males, mean age was 58.2 14.5 years. Mean EQ-5D-5L score = 0.79 0.22 (m …
Clinical efficacy of modified Kamikawa anastomosis in patients with laparoscopic proximal gastrectomy.
Wu CY, Lin JA, Ye K. Wu CY, et al. World J Gastrointest Surg. 2024 Jan 27;16(1):113-123. doi: 10.4240/wjgs.v16.i1.113. World J Gastrointest Surg. 2024. PMID: 38328314 Free PMC article.
All the patients were followed up for 12-23 months. The body mass index at 6 and 12 months after surgery were 22.577 kg/m(2) 3.098 kg/m(2) and 22.594 kg/m(2) 3.207 kg/m(2), respectively. ...Reflux esophagitis and anastomotic stenosis were not observed in any …
All the patients were followed up for 12-23 months. The body mass index at 6 and 12 months after surgery were 22.577 kg/m(2) 3.098 kg …
Effectiveness of a multi-faceted intervention to deprescribe proton pump inhibitors in primary care: protocol for a population-based, pragmatic, cluster-randomized controlled trial.
Nguyen-Soenen J, Rat C, Gaultier A, Schirr-Bonnans S, Tessier P, Fournier JP. Nguyen-Soenen J, et al. BMC Health Serv Res. 2022 Feb 17;22(1):219. doi: 10.1186/s12913-022-07496-3. BMC Health Serv Res. 2022. PMID: 35177042 Free PMC article.
Secondary outcomes will include incremental cost-utility ratio (using EQ-5D-5L scale and National Health Insurance's database), acid rebound (using the Gastroesophageal Reflux Disease Impact Scale), and the patients' attitudes towards deprescribing (using the French …
Secondary outcomes will include incremental cost-utility ratio (using EQ-5D-5L scale and National Health Insurance's database), acid …
Prevalence of upper respiratory symptoms in patients with symptomatic gastroesophageal reflux disease.
Theodoropoulos DS, Ledford DK, Lockey RF, Pecoraro DL, Rodriguez JA, Johnson MC, Boyce HW Jr. Theodoropoulos DS, et al. Am J Respir Crit Care Med. 2001 Jul 1;164(1):72-6. doi: 10.1164/ajrccm.164.1.2006002. Am J Respir Crit Care Med. 2001. PMID: 11435241
Esophageal pH monitoring results were classified as normal, distal, or proximal and distal gastroesophageal reflux using standardized criteria. Mean URS scores (+/- SD) were 8.31 +/- 3.98 in the 52 subjects with GERD and 4.57 +/- 3.57 in the 22 subjects with negativ …
Esophageal pH monitoring results were classified as normal, distal, or proximal and distal gastroesophageal reflux using standardized …
Five-year results of a randomized clinical trial of conventional surgery, endovenous laser ablation and ultrasound-guided foam sclerotherapy in patients with great saphenous varicose veins.
van der Velden SK, Biemans AA, De Maeseneer MG, Kockaert MA, Cuypers PW, Hollestein LM, Neumann HA, Nijsten T, van den Bos RR. van der Velden SK, et al. Br J Surg. 2015 Sep;102(10):1184-94. doi: 10.1002/bjs.9867. Epub 2015 Jul 1. Br J Surg. 2015. PMID: 26132315 Clinical Trial.
Primary outcome was obliteration or absence of the treated GSV segment; secondary outcomes were absence of GSV reflux, and change in Chronic Venous Insufficiency quality-of-life Questionnaire (CIVIQ) and EuroQol - 5D (EQ-5D) scores. ...UGFS was associated wit …
Primary outcome was obliteration or absence of the treated GSV segment; secondary outcomes were absence of GSV reflux, and change in …
Neovascularisation is not an innocent bystander in recurrence after great saphenous vein surgery.
Corbett CR, Prakash V. Corbett CR, et al. Ann R Coll Surg Engl. 2015 Mar;97(2):102-8. doi: 10.1308/003588414X14055925061199. Ann R Coll Surg Engl. 2015. PMID: 25723685 Free PMC article.
METHODS: This was an observational study of 100 limbs (66 patients) operated on by a single surgeon 5-22 years previously (mean: 12 years). The index operation was primary in 54 limbs and for recurrence in 46 limbs. ...All were examined clinically and with duplex ultrasono …
METHODS: This was an observational study of 100 limbs (66 patients) operated on by a single surgeon 5-22 years previously (mean: 12 y …
Recurrence and Its Impact on the Health-related Quality of Life in Patients with Gastroesophageal Reflux Disease: A Prospective Follow-up Analysis.
Min YW, Shin YW, Cheon GJ, Park KS, Kim HS, Sohn CI, Kim TN, Moon HC, Rhee PL. Min YW, et al. J Neurogastroenterol Motil. 2016 Jan 31;22(1):86-93. doi: 10.5056/jnm15124. J Neurogastroenterol Motil. 2016. PMID: 26486229 Free PMC article.
BACKGROUND/AIMS: Limited data exist on the outcome of gastroesophageal reflux disease (GERD) treatment and its impact on the health-related quality of life (HRQoL) in the Asian population. ...The response to treatment was assessed at week 4 (or week 8 for the patients who …
BACKGROUND/AIMS: Limited data exist on the outcome of gastroesophageal reflux disease (GERD) treatment and its impact on the health-r …
Schiff's base derivatives bearing nitroimidazole and quinoline nuclei: new class of anticancer agents and potential EGFR tyrosine kinase inhibitors.
Makawana JA, Sangani CB, Lin L, Zhu HL. Makawana JA, et al. Bioorg Med Chem Lett. 2014 Apr 1;24(7):1734-6. doi: 10.1016/j.bmcl.2014.02.041. Epub 2014 Feb 28. Bioorg Med Chem Lett. 2014. PMID: 24630412
New Schiff's base derivatives 5a-j have been synthesized by reaction between 2-phenoxyquinoline-3-carbaldehydes 3a-j and 2-(2-methyl-5-nitro-1H-imidazol-1-yl)acetohydrazide 4 in presence of nickel(II) nitrate as a catalyst in ethanol under reflux in good yield (78-92%). Al …
New Schiff's base derivatives 5a-j have been synthesized by reaction between 2-phenoxyquinoline-3-carbaldehydes 3a-j and 2-(2-methyl-5-nitro …
Clinical and economic evaluation of laparoscopic surgery compared with medical management for gastro-oesophageal reflux disease: 5-year follow-up of multicentre randomised trial (the REFLUX trial).
Grant AM, Boachie C, Cotton SC, Faria R, Bojke L, Epstein DM, Ramsay CR, Corbacho B, Sculpher M, Krukowski ZH, Heading RC, Campbell MK; REFLUX trial group. Grant AM, et al. Health Technol Assess. 2013 Jun;17(22):1-167. doi: 10.3310/hta17220. Health Technol Assess. 2013. PMID: 23742987 Free PMC article.
MAIN OUTCOME MEASURES: Primary: disease-specific outcome measure (the REFLUX questionnaire); secondary: Short Form questionnaire-36 items (SF-36), European Quality of Life-5 Dimensions (EQ-5D), NHS resource use, reflux medication, complications. ...SF-36 and …
MAIN OUTCOME MEASURES: Primary: disease-specific outcome measure (the REFLUX questionnaire); secondary: Short Form questionnaire-36 i …
13 results