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The following terms were not found in PubMed: 22Receptors, 2Fchemistry, 5BMAJR
Page 1
Postjunctional alpha(2C)-adrenoceptor contractility in human saphenous vein.
Rizzo CA, Ruck LM, Corboz MR, Umland SP, Wan Y, Shah H, Jakway J, Cheng L, McCormick K, Egan RW, Hey JA. Rizzo CA, et al. Eur J Pharmacol. 2001 Feb 16;413(2-3):263-9. doi: 10.1016/s0014-2999(01)00772-5. Eur J Pharmacol. 2001. PMID: 11226402
The alpha(2)-adrenoceptor subtype affinities (pK(i)) obtained in recombinant human alpha(2A)-, alpha(2B)- and alpha(2C)-adrenoceptor competition binding assays were 8.6, 8.3 and 8.6 for yohimbine; 6.3, 8.4 and 7.0 for ARC 239; 8.4, 7.5 and 8.4 for WB 4101 and 7.5, 7.4 and …
The alpha(2)-adrenoceptor subtype affinities (pK(i)) obtained in recombinant human alpha(2A)-, alpha(2B)- and alpha(2C)-adrenoceptor …
A bridging water anchors the tethered 5-(3-aminopropyl)-2'-deoxyuridine amine in the DNA major groove proximate to the N+2 C.G base pair: implications for formation of interstrand 5'-GNC-3' cross-links by nitrogen mustards.
Wang F, Li F, Ganguly M, Marky LA, Gold B, Egli M, Stone MP. Wang F, et al. Biochemistry. 2008 Jul 8;47(27):7147-57. doi: 10.1021/bi800375m. Epub 2008 Jun 13. Biochemistry. 2008. PMID: 18549246 Free PMC article.
Site-specific insertion of 5-(3-aminopropyl)-2'-deoxyuridine (Z3dU) and 7-deaza-dG into the Dickerson-Drew dodecamers 5'-d(C (1)G (2)C (3)G (4)A (5)A (6)T (7)T (8)C (9) Z (10)C (11)G (12))-3'.5'-d(C (13)G (14)C (15)G (16)A (17)A (18)T (19)T (20)C (21) Z (22)C (23)G (24))-3 …
Site-specific insertion of 5-(3-aminopropyl)-2'-deoxyuridine (Z3dU) and 7-deaza-dG into the Dickerson-Drew dodecamers 5'-d(C (1)G (2)C (3)G …
Thieno[3,2-c]pyran-4-one based novel small molecules: their synthesis, crystal structure analysis and in vitro evaluation as potential anticancer agents.
Nakhi A, Adepu R, Rambabu D, Kishore R, Vanaja GR, Kalle AM, Pal M. Nakhi A, et al. Bioorg Med Chem Lett. 2012 Jul 1;22(13):4418-27. doi: 10.1016/j.bmcl.2012.04.109. Epub 2012 May 2. Bioorg Med Chem Lett. 2012. PMID: 22632935
Some of the compounds synthesized showed selective growth inhibition of cancer cells in vitro among which two compounds for example, 5d and 6c showed IC(50) values in the range of 2.0-2.5 muM. The crystal structure analysis of an active compound along with hydrogen bonding …
Some of the compounds synthesized showed selective growth inhibition of cancer cells in vitro among which two compounds for example, 5d
Subtype determination of presynaptic alpha 2-autoreceptors in the rabbit pulmonary artery and human saphenous vein.
Molderings GJ, Göthert M. Molderings GJ, et al. Naunyn Schmiedebergs Arch Pharmacol. 1995 Nov;352(5):483-90. doi: 10.1007/BF00169381. Naunyn Schmiedebergs Arch Pharmacol. 1995. PMID: 8751076
However, in the human saphenous vein oxymetazoline behaved as a partial agonist, which, in interaction experiments with the a2-adrenoceptor agonist B-HT 920 (2-amino-6-allyl-5,6,7,8-tetrahydro-4H-thiazolo-[4,5-d]-azepine), exhibited high potency in antagonizing the inhibitory eff …
However, in the human saphenous vein oxymetazoline behaved as a partial agonist, which, in interaction experiments with the a2-adrenoceptor …