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Year Number of Results
1970 1
1974 1
1977 1
1978 1
1979 3
1981 6
1982 4
1983 7
1984 5
1985 4
1986 10
1987 6
1988 18
1989 12
1990 16
1991 16
1992 19
1993 13
1994 15
1995 22
1996 25
1997 34
1998 37
1999 38
2000 27
2001 32
2002 36
2003 36
2004 46
2005 53
2006 67
2007 53
2008 73
2009 99
2010 89
2011 111
2012 118
2013 143
2014 140
2015 173
2016 155
2017 195
2018 233
2019 236
2020 313
2021 296
2022 328
2023 324
2024 104

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The following terms were ignored: %, %, %, %, %, %, %, %, %, %, %, %, %
The following terms were not found in PubMed: 28Kokocinski, 5BAuthor, 28Kokocinski, 5BAuthor, 28Kokocinsci, 5BAuthor
Page 1
Risk factors of central catheter bloodstream infections in intensive care units: A systematic review and meta-analysis.
Huang H, Chang Q, Zhou Y, Liao L. Huang H, et al. PLoS One. 2024 Apr 23;19(4):e0296723. doi: 10.1371/journal.pone.0296723. eCollection 2024. PLoS One. 2024. PMID: 38652718 Free PMC article.
FINDINGS: A total of 32 studies enrolled, among which eleven factors were identified, they were divided into two categories: modifiable and unmodifiable factors. Modifiable factors: duration of catheterization ( 5d) (OR: 2.07, 95%CI: 1.41-3.03), duration of catheterization …
FINDINGS: A total of 32 studies enrolled, among which eleven factors were identified, they were divided into two categories: modifiable and …
Assessment of Dietary Acid Load in Children with Chronic Kidney Disease: An Observational Study.
Sravani M, Collins S, Iyengar A. Sravani M, et al. Indian J Nephrol. 2024 Jan-Feb;34(1):50-55. doi: 10.4103/ijn.ijn_29_23. Epub 2023 Jul 24. Indian J Nephrol. 2024. PMID: 38645902 Free PMC article.
Owing to the paucity of data in the Indian context, we undertook this cross-sectional study to estimate DAL and assess acid and alkaline food consumption in children with CKD2-5D (Chronic kidney disease stage 2 to 5 and 5D-those on hemodialysis). ...A positive PRAL …
Owing to the paucity of data in the Indian context, we undertook this cross-sectional study to estimate DAL and assess acid and alkaline foo …
Influence of frailty status on the health-related quality of life in older patients with chronic low back pain: a retrospective observational study.
Kim HJ, Jun B, Lee HW, Kim SH. Kim HJ, et al. Qual Life Res. 2024 Apr 20. doi: 10.1007/s11136-024-03658-4. Online ahead of print. Qual Life Res. 2024. PMID: 38642220
Frailty was assessed via the frailty phenotype questionnaire, and HRQoL was evaluated using the EQ-5D-5L. Multiple regression models were used to explore the influence of frailty status on the EQ-5D-5L index and EQ-VAS. Logistic regression was used to determine odds …
Frailty was assessed via the frailty phenotype questionnaire, and HRQoL was evaluated using the EQ-5D-5L. Multiple regression models …
Comparing posterior cervical foraminotomy with anterior cervical discectomy and fusion in radiculopathic patients: an analysis from the Quality Outcomes Database.
Mummaneni PV, Bisson EF, Michalopoulos G, Mualem WJ, El Sammak S, Wang MY, Chan AK, Haid RW, Knightly JJ, Chou D, Sherrod BA, Gottfried ON, Shaffrey CI, Goldberg JL, Virk MS, Hussain I, Agarwal N, Glassman SD, Shaffrey ME, Park P, Foley KT, Pennicooke B, Coric D, Slotkin JR, Potts EA, Fu KG, Asher AL, Bydon M. Mummaneni PV, et al. J Neurosurg Spine. 2024 Apr 19:1-13. doi: 10.3171/2024.2.SPINE221280. Online ahead of print. J Neurosurg Spine. 2024. PMID: 38626479
Outcomes of interest were length of stay, reoperations, patient-reported satisfaction, increase in EQ-5D score, and decrease in Neck Disability Index (NDI) scores for arm and neck pain as long as 1 year after surgery. ...The patients who underwent ACDF had more underlying …
Outcomes of interest were length of stay, reoperations, patient-reported satisfaction, increase in EQ-5D score, and decrease in Neck …
[Buzhong Yiqi Decoction ameliorates spleen deficiency syndrome by regulating gut microbiota].
Yu HC, Meng YY, Wang EK, Yuan JY, Peng Y, Li XB. Yu HC, et al. Zhongguo Zhong Yao Za Zhi. 2024 Feb;49(4):1028-1043. doi: 10.19540/j.cnki.cjcmm.20231013.701. Zhongguo Zhong Yao Za Zhi. 2024. PMID: 38621910 Chinese.
BZYQD inhibited the overgrowth and reduced the richness of gut microbiota in the SF model, and improved the gut microbiota structure in the two models. Algoriphagus, Mycobacterium, and CL500_29_marine_group were the common differential genera in the two models compared wit …
BZYQD inhibited the overgrowth and reduced the richness of gut microbiota in the SF model, and improved the gut microbiota structure in the …
Health economic evaluation of blended collaborative care for older multimorbid heart failure patients: study protocol.
Derendorf L, Stock S, Simic D, Shukri A, Zelenak C, Nagel J, Friede T, Herbeck Belnap B, Herrmann-Lingen C, Pedersen SS, Sørensen J, Müller And On Behalf Of The Escape Consortium D. Derendorf L, et al. Cost Eff Resour Alloc. 2024 Apr 13;22(1):29. doi: 10.1186/s12962-024-00535-2. Cost Eff Resour Alloc. 2024. PMID: 38615050 Free PMC article.
The cost-utility analysis will calculate quality-adjusted life years (QALYs) using the EQ-5D-5L and national value sets. Cost-effectiveness will include the cost per hospital admission avoided and the cost per depression-free days (DFD). ...
The cost-utility analysis will calculate quality-adjusted life years (QALYs) using the EQ-5D-5L and national value sets. Cost-effecti …
Testing the psychometric properties of 9 bolt-ons for the EQ-5D-5L in a general population sample.
Rencz F, Janssen MF. Rencz F, et al. Value Health. 2024 Apr 8:S1098-3015(24)02310-6. doi: 10.1016/j.jval.2024.03.2195. Online ahead of print. Value Health. 2024. PMID: 38599517 Free article.
OBJECTIVES: We aim to assess the psychometric performance and added value of nine existing bolt-ons (breathing problems, cognition, hearing, self-confidence, skin irritation, sleep, social relationships, tiredness and vision) for the EQ-5D-5L in a general population sample …
OBJECTIVES: We aim to assess the psychometric performance and added value of nine existing bolt-ons (breathing problems, cognition, hearing, …
Quality of Life in Patients With Chronic Limb-Threatening Ischemia Treated With Revascularization.
Menard MT, Farber A, Powell RJ, Rosenfield K, Conte MS, Hamza TH, Kaufman JA, Cziraky MJ, Creager MA, Dake MD, Jaff MR, Reid D, Sopko G, White CJ, Strong MB, van Over M, Chisci E, Goodney PP, Gray B, Kayssi A, Siracuse JJ, Choudhry NK; BEST-CLI Investigators. Menard MT, et al. Circulation. 2024 Apr 16;149(16):1241-1253. doi: 10.1161/CIRCULATIONAHA.123.065277. Epub 2024 Apr 10. Circulation. 2024. PMID: 38597097 Free article. Clinical Trial.
HRQoL was assessed over the trial duration using Vascular Quality-of-Life (VascuQoL), European Quality-of-Life-5D (EQ-5D), the Short Form-12 (SF-12) Physical Component Summary (SF-12 PCS), SF-12 Mental Component Summary (SF-12 MCS), Utility Index Score (SF-6D R2), a …
HRQoL was assessed over the trial duration using Vascular Quality-of-Life (VascuQoL), European Quality-of-Life-5D (EQ-5D), the …
Is smokeless tobacco use associated with lower health-related quality of life? A cross-sectional survey among women in Bangladesh.
Huque R, Abdullah SM, Ahmed S, Hossain N, Islam F, Sarker MAB, Amin MN, Ahmed N. Huque R, et al. Tob Induc Dis. 2024 Apr 5;22. doi: 10.18332/tid/185969. eCollection 2024. Tob Induc Dis. 2024. PMID: 38586495 Free PMC article.
The proportion reported any type of problem in all health dimensions was significantly higher among female ST users than non-users (mobility: 43.3% vs 19.5%, self-care: 29.6% vs 11.9%, usual activities: 48.7% vs 21.8%, pain or discomfort: 69.8% vs 40.6%, and anxiety or dep …
The proportion reported any type of problem in all health dimensions was significantly higher among female ST users than non-users (mobility …
Associations of comorbid depression with cardiovascular-renal events and all-cause mortality accounting for patient reported outcomes in individuals with type 2 diabetes: a 6-year prospective analysis of the Hong Kong Diabetes Register.
Yeung YL, Lee KL, Lau ES, Yung TF, Yang A, Wu H, Wong KT, Kong AP, Chow EY, Ma RC, Yeung T, Loo KM, Ozaki R, Luk AO, Lui JN, Chan JC. Yeung YL, et al. Front Endocrinol (Lausanne). 2024 Mar 22;15:1284799. doi: 10.3389/fendo.2024.1284799. eCollection 2024. Front Endocrinol (Lausanne). 2024. PMID: 38586459 Free PMC article.
METHODS: Using prospective data from Hong Kong Diabetes Register (2013-2019), we estimated the hazard-ratio (HR, 95%CI) of depression (validated Patient Health Questionnaire 9 (PHQ-9) score7) with incident cardiovascular disease (CVD), ischemic heart disease (IHD), chronic kidney …
METHODS: Using prospective data from Hong Kong Diabetes Register (2013-2019), we estimated the hazard-ratio (HR, 95%CI) of depression (valid …
Determination of Refractive Error Using Direct Ophthalmoscopy in Children.
Vijendran S, Kamath YS, Alok Y, Kuzhuppilly NIR. Vijendran S, et al. Clin Ophthalmol. 2024 Apr 2;18:989-996. doi: 10.2147/OPTH.S453207. eCollection 2024. Clin Ophthalmol. 2024. PMID: 38584720 Free PMC article.

RESULTS: The presence of superior crescent was associated with hypermetropia (Chi square 37.11, p < 0.001, kappa = 0.15) and inferior crescent with myopia (Chi square 157.29, p < 0.001, kappa = 0.477). Superior crescent was 98.4% sensitive in detecting hypermetropia.

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RESULTS: The presence of superior crescent was associated with hypermetropia (Chi square 37.11, p < 0.001, kappa = 0.15) and inferior cre

…
Comparison of the Real-World Reporting of Symptoms and Well-Being for the HER2-Directed Trastuzumab Biosimilar Ogivri With Registry Data for Herceptin in the Treatment of Breast Cancer: Prospective Observational Study (OGIPRO) of Electronic Patient-Reported Outcomes.
Trojan A, Roth S, Atassi Z, Kiessling M, Zenhaeusern R, Kadvany Y, Schumacher J, Kullak-Ublick GA, Aapro M, Eniu A. Trojan A, et al. JMIR Cancer. 2024 Apr 4;10:e54178. doi: 10.2196/54178. JMIR Cancer. 2024. PMID: 38573759 Free PMC article.
Patients used the medidux app to dynamically record symptoms (according to the Common Terminology Criteria for Adverse Events [CTCAE]), well-being (according to the Eastern Cooperative Oncology Group Performance Status scale), QoL (using the EQ-5D-5L questionnaire), cognit …
Patients used the medidux app to dynamically record symptoms (according to the Common Terminology Criteria for Adverse Events [CTCAE]), well …
Apnea, Intermittent Hypoxemia, and Bradycardia Events Predict Late-Onset Sepsis in Extremely Preterm Infants.
Kausch SL, Lake DE, Di Fiore JM, Weese-Mayer DE, Claure N, Ambalavanan N, Vesoulis ZA, Fairchild KD, Dennery PA, Hibbs AM, Martin RJ, Premananda I, Travers CP, Bancalari E, Hamvas A, Kemp JS, Carroll JL, Moorman JR, Sullivan BA; Prematurity-Related Ventilatory Control (Pre-Vent) Investigators. Kausch SL, et al. J Pediatr. 2024 Apr 1:114042. doi: 10.1016/j.jpeds.2024.114042. Online ahead of print. J Pediatr. 2024. PMID: 38570031
OBJECTIVE: To examine the association of cardiorespiratory events, including apnea, periodic breathing, intermittent hypoxemia (IH), and bradycardia, with late-onset sepsis for extremely preterm infants (<29 weeks' gestational age [GA]) on versus off invasive mechanical …
OBJECTIVE: To examine the association of cardiorespiratory events, including apnea, periodic breathing, intermittent hypoxemia (IH), and bra …
Parenteral n-3 polyunsaturated fatty acids supplementation improves postoperative recovery for patients with Crohn's disease after bowel resection: a randomized, unblinded controlled clinical trial.
Ge X, Liu H, Wu Y, Liu W, Qi W, Ye L, Cao Q, Lian H, Bai R, Zhou W. Ge X, et al. Am J Clin Nutr. 2024 Apr;119(4):1027-1035. doi: 10.1016/j.ajcnut.2023.12.022. Epub 2024 Feb 19. Am J Clin Nutr. 2024. PMID: 38569774 Clinical Trial.
In the secondary outcomes, the mean standard deviation of interleukin (IL)-6 (17.11 2.14 pg/mL compared with 30.50 5.14 pg/mL; P = 0.014), IL-1beta (2.01 0.05 pg/mL compared with 2.24 0.09 pg/mL; P = 0.019), tumor necrosis factor-alpha (2.09 0.06 pg/mL compared with 2.29 0 …
In the secondary outcomes, the mean standard deviation of interleukin (IL)-6 (17.11 2.14 pg/mL compared with 30.50 5.14 pg/mL; P = 0.014), I …
The feasibility, repeatability, validity and responsiveness of the EQ-5D-3L in Krio for patients with stroke in Sierra Leone.
Youkee D, Pessima S, Sackley C, Soley-Bori M, Deen GF, Marshall IJ. Youkee D, et al. Health Qual Life Outcomes. 2024 Mar 28;22(1):29. doi: 10.1186/s12955-024-02246-x. Health Qual Life Outcomes. 2024. PMID: 38549069 Free PMC article.
Convergent validity with BI was strong overall and for shared subscales. EQ-5D-3L was moderately responsive to both improvement Cohen's D 0.55 (95% CI:0.15-0.94) and deterioration 0.92 (95% CI:0.29-1.55). ...Development of an EQ-5D value set for West Africa s …
Convergent validity with BI was strong overall and for shared subscales. EQ-5D-3L was moderately responsive to both improvement Cohen …
Design, Synthesis, and Biological Evaluation of Novel Phenoxy Acetic Acid Derivatives as Selective COX-2 Inhibitors Coupled with Comprehensive Bio-Pharmacological Inquiry, Histopathological Profiling, and Toxicological Scrutiny.
Alshaye NA, Elgohary MK, Elkotamy MS, Abdel-Aziz HA. Alshaye NA, et al. Molecules. 2024 Mar 15;29(6):1309. doi: 10.3390/molecules29061309. Molecules. 2024. PMID: 38542945 Free PMC article.
Herein, we aimed at the design and synthesis of new anti-inflammatory agents 5a-f, 7a-b, 10a-f, and 13a-b with expected selective inhibition for COX-2. Compounds 5d-f, 7b, and 10c-f showed significant COX-2 inhibition with IC(50) in the range of …
Herein, we aimed at the design and synthesis of new anti-inflammatory agents 5a-f, 7a-b, 10a-f, and 13a-b with expected select …
Status and Barriers of Physical Activity and Exercise in Community-Dwelling Stroke Patients in South Korea: A Survey-Based Study.
Lee JL, Kim Y, Huh S, Shin YI, Ko SH. Lee JL, et al. Healthcare (Basel). 2024 Mar 20;12(6):697. doi: 10.3390/healthcare12060697. Healthcare (Basel). 2024. PMID: 38540661 Free PMC article.
Overall, 96% of the respondents recognized the need to exercise, and two-thirds exercised. The third who did not exercise cited disability (29%), lack of facilities (22%), and health concerns (13%); only 21% of participants had ever used a community exercise facility, and …
Overall, 96% of the respondents recognized the need to exercise, and two-thirds exercised. The third who did not exercise cited disability ( …
Integrating Fall Prevention Strategies into EMS Services to Reduce Falls and Associated Healthcare Costs for Older Adults.
Camp K, Murphy S, Pate B. Camp K, et al. Clin Interv Aging. 2024 Mar 22;19:561-569. doi: 10.2147/CIA.S453961. eCollection 2024. Clin Interv Aging. 2024. PMID: 38533419 Free PMC article.
The HUG and HRA programs measured change in quality of life with EuroQol-5D, referral service utilization, falls, emergent healthcare utilization, and hospital readmission data. ...Services provided through the HUG and HRA programs, along with additional needed referral se …
The HUG and HRA programs measured change in quality of life with EuroQol-5D, referral service utilization, falls, emergent healthcare …
Parametric analysis of the transmission dynamics during indigenous aggregated outbreaks caused by five SARS-CoV-2 strains in Nanjing, China.
Ma T, Chen C, Wang J, Wang H, Zhao Y, Zhu Y, Yan Z, Ding S, Ding J. Ma T, et al. Front Public Health. 2024 Mar 8;12:1358577. doi: 10.3389/fpubh.2024.1358577. eCollection 2024. Front Public Health. 2024. PMID: 38525336 Free PMC article.

Notably, the incubation period and SI of the five had both a progressive shortening trend (p < 0.001); Moreover, R(0) of the five were 2.39 (95% CI: 1.30-4.29), 3.73 (95% CI: 2.66-5.15), 5.28 (95% CI: 3.52-8.10), 5.54 (95% CI: 2.69-11.17), 7.39 (95% CI: 2.97-18.76), wit

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Notably, the incubation period and SI of the five had both a progressive shortening trend (p < 0.001); Moreover, R(0) of the five were 2.

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Real world insights for psoriasis: the association of severity of skin lesions with work productivity, medical consumption costs and quality of life.
Lysen TS, Crombag EJGM, Lennaerts L, Makady A, Bruin RH, Mulder K, de Jong EMGJ, van Ballegooijen H. Lysen TS, et al. J Dermatolog Treat. 2024 Dec;35(1):2332615. doi: 10.1080/09546634.2024.2332615. Epub 2024 Mar 24. J Dermatolog Treat. 2024. PMID: 38522860 Free article.
We used validated instruments to assess work productivity (WPAI-PsO), medical consumption costs (iMCQ), and health-related quality of life (EQ-5D-5L and the DLQI). We used ordinal logistic regression to associate BSA categories >1% versus 0-1% with outcomes adjusted for …
We used validated instruments to assess work productivity (WPAI-PsO), medical consumption costs (iMCQ), and health-related quality of life ( …
Factors associated with sedentary behavior among community-dwelling breast cancer survivors aged 50 years or older.
Park JH, Lee JS, Nam HS, Kim YH. Park JH, et al. Sci Rep. 2024 Mar 21;14(1):2396. doi: 10.1038/s41598-024-51172-x. Sci Rep. 2024. PMID: 38514659 Free PMC article.
Among the Korean community-dwelling breast cancer survivors, 48.2% had a high daily sedentary time. Insufficient aerobic exercise (OR 2.29; 95% CI 1.12-4.69), diabetes (OR 3.37; 95% CI 1.22-9.33), and unemployed status (OR 2.29; 95% CI 1.05-5.02) were independently …
Among the Korean community-dwelling breast cancer survivors, 48.2% had a high daily sedentary time. Insufficient aerobic exercise (OR 2.2 …
The dynamic features and microbial mechanism of nitrogen transformation for hydrothermal aqueous phase as fertilizer in dryland soil.
Huang H, He M, Liu X, Ma X, Yang Y, Shen Y, Yang Y, Zhen Y, Wang J, Zhang Y, Wang S, Shan X, Fan W, Guo D, Niu Z. Huang H, et al. J Environ Manage. 2024 Apr;356:120643. doi: 10.1016/j.jenvman.2024.120643. Epub 2024 Mar 20. J Environ Manage. 2024. PMID: 38513582
The high-molecular-weight SOMs relatively increased during 5-30 d and then biodegraded during 30-90 d, which SUV(254) changed from 0.51 to 1.47 to 0.29 L(-1) m(-1). This affected ureC that changed from 5.58 to 5.34 to 5.75 lg copies g(-1). ...
The high-molecular-weight SOMs relatively increased during 5-30 d and then biodegraded during 30-90 d, which SUV(254) changed from 0.51 to 1 …
Cost-effectiveness and cost-utility study of a psychoeducational group intervention for people with depression and physical comorbidity in primary care.
Raya-Tena A, Fernández-San-Martín MI, Martín-Royo J, Casajuana-Closas M, Jiménez-Herrera MF; Grup Psicodep. Raya-Tena A, et al. Enferm Clin (Engl Ed). 2024 Mar 18:S2445-1479(24)00024-9. doi: 10.1016/j.enfcle.2024.03.005. Online ahead of print. Enferm Clin (Engl Ed). 2024. PMID: 38508236
MEASUREMENTS: Effectiveness: depression-free days (DFD) calculated from the BDI-II and quality-adjusted life years (QALYs) from the Euroqol-5D. Direct costs: PC visits, mental health, emergencies and hospitalizations, drugs. ...QALYs were similar (difference -0.01, 95% CI …
MEASUREMENTS: Effectiveness: depression-free days (DFD) calculated from the BDI-II and quality-adjusted life years (QALYs) from the Euroqol- …
Design, synthesis and anti-oomycete activity of 2-acyloxyhinokitiol derivatives.
Wei R, Liu Y, Yin W, Wang R, Tian Y, Huang X, Qian L, Liu S, Chen G, Che Z. Wei R, et al. Nat Prod Res. 2024 Mar 19:1-10. doi: 10.1080/14786419.2024.2331021. Online ahead of print. Nat Prod Res. 2024. PMID: 38501725
Among the ten hinokitiol ester derivatives tested, four compounds 5d, 5g, 5h and 5j had anti-oomycete activity higher than the positive control zoxamide (EC(50) = 23.59 mg/L), and the EC(50) values of 18.90, 20.62, 13.61 and 21.29 mg/L, respectively. ...
Among the ten hinokitiol ester derivatives tested, four compounds 5d, 5g, 5h and 5j had anti-oomycete activity higher than the positi …
Optical properties of blue-light-emitting Y2 O3 :Ce nanophosphor for solid-state lighting application.
Dutta M, Kalita JM, Wary G. Dutta M, et al. Luminescence. 2024 Mar;39(3):e4718. doi: 10.1002/bio.4718. Luminescence. 2024. PMID: 38501347
The samples had a body-centred cubic crystal structure. The undoped sample had a crystallite size of 29.03 nm, and it varied after doping with Ce. The grain size of the samples varied from 23.00 to 50.78 nm. All the samples exhibited a strong absorption band at 206 nm due …
The samples had a body-centred cubic crystal structure. The undoped sample had a crystallite size of 29.03 nm, and it varied after do …
Luminescence properties and Judd-Ofelt analysis of Tb3+ doped Sr2YTaO6 double perovskite phosphors for white LED applications.
Wang L, Zhang Y, Gao D, Sha X, Chen X, Zhang Y, Zhang J, Zhang X, Cao Y, Wang Y, Li X, Xu S, Yu H, Chen B. Wang L, et al. Dalton Trans. 2024 Apr 2;53(14):6399-6409. doi: 10.1039/d4dt00302k. Dalton Trans. 2024. PMID: 38498319
Moreover, the Judd-Ofelt parameters were calculated from the emission spectra of SYT:Tb(3+) to be omega(2) = 0.29 10(-20), omega(4) = 0.45 10(-20), and omega(6) = 0.72 10(-20) cm(2), respectively. ...
Moreover, the Judd-Ofelt parameters were calculated from the emission spectra of SYT:Tb(3+) to be omega(2) = 0.29 10(-20), omega(4) = …
Effects of Exercise Training Response on Quality of Life and Cardiovascular Risk Factor Profiles in People With Coronary Artery Disease: Insights From the HIIT or MISS UK Trial.
Ingle L, Powell R, Begg B, Birkett ST, Nichols S, Ennis S, Banerjee P, Shave R, McGregor G. Ingle L, et al. Arch Phys Med Rehabil. 2024 Mar 16:S0003-9993(24)00883-9. doi: 10.1016/j.apmr.2024.03.002. Online ahead of print. Arch Phys Med Rehabil. 2024. PMID: 38493909
PARTICIPANTS: 382 participants with CAD (N=382) (mean age: 58.89.6y; mean body mass index: 29.04.3 kg/m(2)). MAIN OUTCOME MEASURES: We identified responders and nonresponders based on a meaningful change in Vo(2)peak, using 2 established methods. ...Responders were more li …
PARTICIPANTS: 382 participants with CAD (N=382) (mean age: 58.89.6y; mean body mass index: 29.04.3 kg/m(2)). MAIN OUTCOME MEASURES: W …
Health-related quality of life and its determinants among cancer patients: evidence from 12,148 patients of Indian database.
Dixit J, Gupta N, Kataki A, Roy P, Mehra N, Kumar L, Singh A, Malhotra P, Gupta D, Goyal A, Rajsekar K, Krishnamurthy MN, Gupta S, Prinja S. Dixit J, et al. Health Qual Life Outcomes. 2024 Mar 13;22(1):26. doi: 10.1186/s12955-024-02227-0. Health Qual Life Outcomes. 2024. PMID: 38481231 Free PMC article.
METHODS: Data were collected from 12,148 patients, sampled from seven purposively chosen leading cancer hospitals in India, to elicit HRQoL using the EuroQol questionnaire comprising of 5-dimensions and 5-levels (EQ-5D-5L). Multiple linear regression was used to determine …
METHODS: Data were collected from 12,148 patients, sampled from seven purposively chosen leading cancer hospitals in India, to elicit HRQoL …
Impact of Primary Tumor Location on Demographics, Resectability, Outcomes, and Quality of Life in Finnish Metastatic Colorectal Cancer Patients (Subgroup Analysis of the RAXO Study).
Aho S, Osterlund E, Ristimäki A, Nieminen L, Sundström J, Mäkinen MJ, Kuopio T, Kytölä S, Ålgars A, Ristamäki R, Heervä E, Kallio R, Halonen P, Soveri LM, Nordin A, Uutela A, Salminen T, Stedt H, Lamminmäki A, Muhonen T, Kononen J, Glimelius B, Isoniemi H, Lehto JT, Lehtomäki K, Osterlund P. Aho S, et al. Cancers (Basel). 2024 Mar 5;16(5):1052. doi: 10.3390/cancers16051052. Cancers (Basel). 2024. PMID: 38473410 Free PMC article.
Health-related quality of life (HRQoL) was assessed multi-cross-sectionally with QLQ-C30, QLQ-CR29, EQ-5D, and 15D. A chi-square, Kaplan-Meier, and Cox regression were used to compare the groups. The PTL was in the right colon in 310 patients (29%), the left colon i …
Health-related quality of life (HRQoL) was assessed multi-cross-sectionally with QLQ-C30, QLQ-CR29, EQ-5D, and 15D. A chi-square, Kap …
Effect of etranacogene dezaparvovec on quality of life for severe and moderately severe haemophilia B participants: Results from the phase III HOPE-B trial 2 years after gene therapy.
Itzler R, Buckner TW, Leebeek FWG, Miller J, Recht M, Drelich D, Monahan PE, Pipe SW. Itzler R, et al. Haemophilia. 2024 Mar 10. doi: 10.1111/hae.14977. Online ahead of print. Haemophilia. 2024. PMID: 38462823
METHODS: HRQoL was evaluated using generic and disease-specific patient reported outcomes (PROs) including the EQ-5D-5L and the Hem-A-QoL questionnaires. Mean domain and total scores were compared 6 months pre- and the first 2 years post-EDZ administration using repeated m …
METHODS: HRQoL was evaluated using generic and disease-specific patient reported outcomes (PROs) including the EQ-5D-5L and the Hem-A …
Intramammary lipopolysaccharide challenge in early versus mid-lactation dairy cattle: immune, production, and metabolic responses.
Opgenorth J, Abeyta MA, Goetz BM, Rodriguez-Jimenez S, Freestone AD, Rhoads RP, McMillan RP, McGill JL, Baumgard LH. Opgenorth J, et al. J Dairy Sci. 2024 Mar 7:S0022-0302(24)00536-8. doi: 10.3168/jds.2023-24488. Online ahead of print. J Dairy Sci. 2024. PMID: 38460880 Free article.
Circulating glucose was not affected by LPS. Nonesterified fatty acids (NEFA) decreased in E-LPS (29%) but not M-LPS cows. beta-hydroxybutyrate (BHB) slightly increased (14%) over time post-LPS regardless of LS. ...
Circulating glucose was not affected by LPS. Nonesterified fatty acids (NEFA) decreased in E-LPS (29%) but not M-LPS cows. beta-hydro …
The prolonged impact of COVID-19 on symptoms, health-related quality of life, fatigue and mental well-being: a cross-sectional study.
Brus IM, Spronk I, Haagsma JA, de Groot A, Tieleman P, Biere-Rafi S, Polinder S. Brus IM, et al. Front Epidemiol. 2023 Jun 22;3:1144707. doi: 10.3389/fepid.2023.1144707. eCollection 2023. Front Epidemiol. 2023. PMID: 38455946 Free PMC article.
Respondents 3-6 months post-acute infection had the lowest HRQoL (median EQ-5D utility score: 0.59), the highest fatigue level (median score: 110.0) and the highest proportion with a likely depressive disorder (32.4%), whereas respondents 13-18 months post-infection had th …
Respondents 3-6 months post-acute infection had the lowest HRQoL (median EQ-5D utility score: 0.59), the highest fatigue level (media …
Assessing the Modified Frailty Index and Post-Operative Outcomes in Adhesive Small Bowel Obstruction: A Retrospective Cohort Study.
Talwar G, McKechnie T, Patel J, Qiu R, Wu K, Lee Y, Hong D, Doumouras A, Bogach J, Eskicioglu C. Talwar G, et al. J Surg Res. 2024 May;297:71-82. doi: 10.1016/j.jss.2023.12.008. Epub 2024 Mar 5. J Surg Res. 2024. PMID: 38447338
However, on multiple regression, functional dependence but not the mFI, was independently associated with worse 30-d overall morbidity (odds ratio [OR] 3.97, confidence interval [CI] 1.29-12.19) and lower likelihood of returning to preoperative disposition (OR 0.21, CI 0.0 …
However, on multiple regression, functional dependence but not the mFI, was independently associated with worse 30-d overall morbidity (odds …
Adherence to heart failure treatment in patients with peripartum cardiomyopathy.
Hoevelmann J, Sliwa K, Schaar JM, Briton O, Böhm M, Meyer MR, Viljoen C. Hoevelmann J, et al. ESC Heart Fail. 2024 Mar 4. doi: 10.1002/ehf2.14712. Online ahead of print. ESC Heart Fail. 2024. PMID: 38439175 Free article.
Participants were thereby classified as 'adherent' (i.e. all prescribed HF drugs were detectable by LC-HRMS), 'partially adherent' (i.e. at least one prescribed drug detectable) or 'non-adherent' (i.e. none of the prescribed drugs detectable). Health state index scores were asses …
Participants were thereby classified as 'adherent' (i.e. all prescribed HF drugs were detectable by LC-HRMS), 'partially adherent' (i.e. at …
Reliability and Validity of the Korean Version of the Somatic Symptom Disorder-B Criteria Scale in a Clinical Population.
Jung S, Shin JS, Lee SH, Lee S, Kim J, Son KL, Hahm BJ, Yeom CW. Jung S, et al. Psychiatry Investig. 2024 Feb;21(2):165-173. doi: 10.30773/pi.2023.0352. Epub 2024 Feb 22. Psychiatry Investig. 2024. PMID: 38433415 Free PMC article.
The SSD-12 construct and concurrent validity were assessed by examining the correlations with Generalized Anxiety Disorder-7 (GAD-7), Patient Health Questionnaire-9 (PHQ-9), PHQ-15, 5-level EQ-5D version (EQ-5D-5L), and World Health Organization Quality of Life Brie …
The SSD-12 construct and concurrent validity were assessed by examining the correlations with Generalized Anxiety Disorder-7 (GAD-7), Patien …
Patient attitudes towards day-case hip and knee arthroplasty.
Halken CH, Bredgaard Jensen C, Henkel C, Gromov K, Troelsen A. Halken CH, et al. Bone Joint J. 2024 Mar 1;106-B(3 Supple A):3-9. doi: 10.1302/0301-620X.106B3.BJJ-2023-0827.R1. Bone Joint J. 2024. PMID: 38425308
Approximately 20% of patients responded 'Do not know' regardless of age, sex, and PROMs. Patients reporting anxiety/depression based on EQ-5D-3L more frequently answered 'No' (56.9%; 66/116) compared to those not experiencing anxiety/depression (34.9%; 1,356/3,890). Among …
Approximately 20% of patients responded 'Do not know' regardless of age, sex, and PROMs. Patients reporting anxiety/depression based on EQ- …
Modified 2-stage IPAA has similar postoperative complication rates and functional outcomes compared to 3-stage IPAA.
Clement E, Lin W, Shojaei D, Au-Yeung P, Motamedi A, Phang PT. Clement E, et al. Am J Surg. 2024 May;231:96-99. doi: 10.1016/j.amjsurg.2024.02.032. Epub 2024 Feb 24. Am J Surg. 2024. PMID: 38423807 Free article.
METHODS: Charts were reviewed for adult UC patients undergoing IPAA between 2010 and 2020. QOL and function were assessed with EQ-5D-3L Quality of Life and Pouch Functional Score questionnaires. RESULTS: 152 patients were identified. 43 modified 2-stage and 109 3-stage IPA …
METHODS: Charts were reviewed for adult UC patients undergoing IPAA between 2010 and 2020. QOL and function were assessed with EQ-5D- …
Survival and Quality of Life after Isolated Hepatic Perfusion with Melphalan as a Treatment for Uveal Melanoma Liver Metastases - Final Results from the Phase III Randomized Controlled Trial SCANDIUM.
Olofsson Bagge R, Nelson A, Shafazand A, All-Eriksson C, Cahlin C, Elander N, Gustavsson A, Helgadottir H, Kiilgaard JF, Kinhult S, Ljuslinder I, Mattsson J, Rizell M, Sternby Eilard M, Ullenhag GJ, Nilsson JA, Ny L, Lindnér P. Olofsson Bagge R, et al. Ann Surg. 2024 Feb 29. doi: 10.1097/SLA.0000000000006255. Online ahead of print. Ann Surg. 2024. PMID: 38420778
In the ITT population, the median PFS was 7.4 months in the IHP group compared with 3.3 months in the control group, with a hazard ratio of 0.21 (95% CI, 0.12-0.36). The 24-month OS rate was 46.5% in the IHP group versus 29.5% in the control group (P=0.12). The median OS w …
In the ITT population, the median PFS was 7.4 months in the IHP group compared with 3.3 months in the control group, with a hazard ratio of …
Time-action and patient experience analyses of locally advanced cervical cancer brachytherapy.
van Vliet-Pérez SM, van Paassen R, Wauben LSGL, Straathof R, Berg NJV, Dankelman J, Heijmen BJM, Kolkman-Deurloo IK, Nout RA. van Vliet-Pérez SM, et al. Brachytherapy. 2024 Feb 27:S1538-4721(24)00011-4. doi: 10.1016/j.brachy.2024.01.007. Online ahead of print. Brachytherapy. 2024. PMID: 38418362 Free article.
MATERIALS AND METHODS: LACC patients treated with IGABT were included for the time-action (56 patients) and patient experience (29 patients) analyses. Times per treatment step were reported on a standardized form. For the patient experience analysis, a baseline health stat …
MATERIALS AND METHODS: LACC patients treated with IGABT were included for the time-action (56 patients) and patient experience (29 pa …
Population Norms for the EQ-5D-5L, PROPr and SF-6D in Hungary.
Nikl A, Janssen MF, Jenei B, Brodszky V, Rencz F. Nikl A, et al. Pharmacoeconomics. 2024 May;42(5):583-603. doi: 10.1007/s40273-024-01360-4. Epub 2024 Feb 28. Pharmacoeconomics. 2024. PMID: 38416366
METHODS: In November 2020, an online cross-sectional survey was conducted among a representative sample of the Hungarian adult general population (n = 1631). Respondents completed the Hungarian versions of the EQ-5D-5L, PROMIS-29+2 version 2.1 and 36-item Short Form …
METHODS: In November 2020, an online cross-sectional survey was conducted among a representative sample of the Hungarian adult general popul …
The clinical and radiographic degenerative spondylolisthesis classification and its predictive value.
Bäcker HC, Turner P, Johnson MA, Apos E, Cunningham J. Bäcker HC, et al. Arch Orthop Trauma Surg. 2024 Apr;144(4):1597-1601. doi: 10.1007/s00402-024-05261-1. Epub 2024 Feb 28. Arch Orthop Trauma Surg. 2024. PMID: 38416138
Data on demographics, patient reported outcome measures including the Oswestry Disability Index (ODI) and EQ-5D-3 L scores, and changes in radiographic measurements were analysed. ...The mean age was 65.3 11.3years and females were predominantly affected (61%). Most cases …
Data on demographics, patient reported outcome measures including the Oswestry Disability Index (ODI) and EQ-5D-3 L scores, and chang …
Non-clotting factor therapies for preventing bleeds in people with congenital hemophilia A or B.
Olasupo OO, Noronha N, Lowe MS, Ansel D, Bhatt M, Matino D. Olasupo OO, et al. Cochrane Database Syst Rev. 2024 Feb 27;2(2):CD014544. doi: 10.1002/14651858.CD014544.pub2. Cochrane Database Syst Rev. 2024. PMID: 38411279 Review.
Emicizumab 1.5 mg/kg/week did not improve Haem-A-QoL physical and total health scores, EQ-5D-5L VAS, or utility index scores (low-certainty evidence) when compared with on-demand therapy at 25 weeks. Emicizumab 3.0 mg/kg bi-weekly may improve HRQoL measured by the Haem-A-Q …
Emicizumab 1.5 mg/kg/week did not improve Haem-A-QoL physical and total health scores, EQ-5D-5L VAS, or utility index scores (low-cer …
High survivorship and low complication rate in a single-centre series of 651 medial opening wedge high tibial osteotomy cases with a mean follow-up of 13 years.
Mabrouk A, Risebury M, Yasen S. Mabrouk A, et al. Knee Surg Sports Traumatol Arthrosc. 2024 Mar;32(3):736-749. doi: 10.1002/ksa.12096. Epub 2024 Feb 27. Knee Surg Sports Traumatol Arthrosc. 2024. PMID: 38410856
A total of 651 cases, with a mean age of 46.7 9 years and a mean body mass index of 29.6 5.2 kg/m(2) , were included. This comprised 71% males (n = 462) and 29% females (n = 189). ...This included the Knee injury and Osteoarthritis Outcome Scores, the Oxford Knee Sc …
A total of 651 cases, with a mean age of 46.7 9 years and a mean body mass index of 29.6 5.2 kg/m(2) , were included. This comprised …
A comparison of keratoconus progression following collagen cross-linkage using standard or personalised keratometry thresholds.
Li JO, Maile HP, Bunce C, Kandakji L, Leucci MT, Allan BD, Tuft SJ, Pontikos N, Gore DM. Li JO, et al. Eye (Lond). 2024 Feb 26. doi: 10.1038/s41433-024-02994-6. Online ahead of print. Eye (Lond). 2024. PMID: 38409307
The primary outcome was progression five years after a baseline visit 9-15 months following CXL. RESULTS: Progression rates were 8% with a standard ( 1.5D) threshold for K2 or 6% with the static multi-parameter definition. With a 1D threshold for Kmax, the progression was …
The primary outcome was progression five years after a baseline visit 9-15 months following CXL. RESULTS: Progression rates were 8% with a s …
Patient acceptable symptom state and treatment failure threshold values for work productivity and activity Impairment and EQ-5D-5L in osteoarthritis.
Kiadaliri A, Cronström A, Dahlberg LE, Lohmander LS. Kiadaliri A, et al. Qual Life Res. 2024 Feb 26. doi: 10.1007/s11136-024-03602-6. Online ahead of print. Qual Life Res. 2024. PMID: 38409279
RESULTS: Around 42.0% and 48.3% of the participants rated their current state as acceptable, while 4.2% and 2.8% considered the treatment had failed at 3 and 12 months, respectively. The 3-month PASS/TF thresholds were 16/29 (work impairment), 26/50 (activity impairment), …
RESULTS: Around 42.0% and 48.3% of the participants rated their current state as acceptable, while 4.2% and 2.8% considered the treatment ha …
Comparison of proximal and minus lens autorefraction techniques to measure monocular accommodative amplitude.
Parks SM, Kulp MT, Anderson HA. Parks SM, et al. Optom Vis Sci. 2024 Feb 1;101(2):109-116. doi: 10.1097/OPX.0000000000002103. Epub 2024 Jan 6. Optom Vis Sci. 2024. PMID: 38408308
Differences in amplitude between the proximal and proximal-lens (letter) protocol were different by age group (p = 0 .003), with the youngest group having larger differences (1.14 1.58 D) than the oldest groups (0.17 0.58 and 0.29 0.48 D, respectively) by post hoc Tukey an …
Differences in amplitude between the proximal and proximal-lens (letter) protocol were different by age group (p = 0 .003), with the younges …
Health utility among people who regularly use opioids in Australia.
Tran AD, Grebely J, Chambers M, Degenhardt L, Farrell M, Bajis S, Larance B. Tran AD, et al. Drug Alcohol Rev. 2024 Feb 25. doi: 10.1111/dar.13823. Online ahead of print. Drug Alcohol Rev. 2024. PMID: 38403293
To address the unique distribution of EQ-5D-5L health utility scores in the current sample, a two-part model was applied to assess factors associated with health utility. RESULTS: Among 402 participants enrolled in the study, 385 (96%) completed the EQ-5D-5L questio …
To address the unique distribution of EQ-5D-5L health utility scores in the current sample, a two-part model was applied to assess fa …
Effects of a multistrain Bacillus-based direct-fed microbial on gastrointestinal permeability and biomarkers of inflammation during and following feed restriction in mid-lactation Holstein cows.
Goetz BM, Abeyta MA, Rodriguez-Jimenez S, Opgenorth J, McGill JL, Fensterseifer SR, Arias RP, Lange AM, Galbraith EA, Baumgard LH. Goetz BM, et al. J Dairy Sci. 2024 Feb 21:S0022-0302(24)00502-2. doi: 10.3168/jds.2023-24352. Online ahead of print. J Dairy Sci. 2024. PMID: 38395402 Free article.
Overall, circulating LBP and Hp tended to be increased in DFM15 cows relative to DFM10 (29 and 81%, respectively), but no treatment differences were observed for SAA. ...
Overall, circulating LBP and Hp tended to be increased in DFM15 cows relative to DFM10 (29 and 81%, respectively), but no treatment d …
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