Sixty Years of Placebo-Controlled Antipsychotic Drug Trials in Acute Schizophrenia: Systematic Review, Bayesian Meta-Analysis, and Meta-Regression of Efficacy Predictors.
Leucht S, Leucht C, Huhn M, Chaimani A, Mavridis D, Helfer B, Samara M, Rabaioli M, Bächer S, Cipriani A, Geddes JR, Salanti G, Davis JM.
Leucht S, et al.
Am J Psychiatry. 2017 Oct 1;174(10):927-942. doi: 10.1176/appi.ajp.2017.16121358. Epub 2017 May 25.
Am J Psychiatry. 2017.
PMID: 28541090
Free article.
However, in a multivariable meta-regression, only industry sponsorship and increasing placebo response were significant moderators of effect sizes. ...CONCLUSIONS: Approximately twice as many patients improved with antipsychotics as with placebo, but only a minority …
However, in a multivariable meta-regression, only industry sponsorship and increasing placebo response were significant modera …