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Heteroplasmy levels of a mitochondrial gene mutation associated with diabetes mellitus decrease in leucocyte DNA upon aging.
't Hart LM, Jansen JJ, Lemkes HH, de Knijff P, Maassen JA. 't Hart LM, et al. Hum Mutat. 1996;7(3):193-7. doi: 10.1002/(SICI)1098-1004(1996)7:3<193::AID-HUMU2>3.0.CO;2-C. Hum Mutat. 1996. PMID: 8829651
Progressive sensorineural hearing impairment in maternally inherited diabetes mellitus and deafness (MIDD).
Hendrickx JJ, Mudde AH, 't Hart LM, Huygen PL, Cremers CW. Hendrickx JJ, et al. Otol Neurotol. 2006 Sep;27(6):802-8. doi: 10.1097/01.mao.0000224091.02506.a0. Otol Neurotol. 2006. PMID: 16788417
Lessons that can be learned from patients with diabetogenic mutations in mitochondrial DNA: implications for common type 2 diabetes.
Maassen JA, 't Hart LM, Ouwens DM. Maassen JA, et al. Curr Opin Clin Nutr Metab Care. 2007 Nov;10(6):693-7. doi: 10.1097/MCO.0b013e3282f0b774. Curr Opin Clin Nutr Metab Care. 2007. PMID: 18089949 Review.
HbA1c is associated with altered expression in blood of cell cycle- and immune response-related genes.
Slieker RC, van der Heijden AAWA, van Leeuwen N, Mei H, Nijpels G, Beulens JWJ, 't Hart LM. Slieker RC, et al. Diabetologia. 2018 Jan;61(1):138-146. doi: 10.1007/s00125-017-4467-0. Epub 2017 Nov 20. Diabetologia. 2018. PMID: 29159468 Free PMC article.
The association of mitochondrial content with prevalent and incident type 2 diabetes.
Reiling E, Ling C, Uitterlinden AG, Van't Riet E, Welschen LM, Ladenvall C, Almgren P, Lyssenko V, Nijpels G, van Hove EC, Maassen JA, de Geus EJ, Boomsma DI, Dekker JM, Groop L, Willemsen G, 't Hart LM. Reiling E, et al. J Clin Endocrinol Metab. 2010 Apr;95(4):1909-15. doi: 10.1210/jc.2009-1775. Epub 2010 Feb 11. J Clin Endocrinol Metab. 2010. PMID: 20150578
Genetic association analysis of 13 nuclear-encoded mitochondrial candidate genes with type II diabetes mellitus: the DAMAGE study.
Reiling E, van Vliet-Ostaptchouk JV, van 't Riet E, van Haeften TW, Arp PA, Hansen T, Kremer D, Groenewoud MJ, van Hove EC, Romijn JA, Smit JW, Nijpels G, Heine RJ, Uitterlinden AG, Pedersen O, Slagboom PE, Maassen JA, Hofker MH, 't Hart LM, Dekker JM. Reiling E, et al. Eur J Hum Genet. 2009 Aug;17(8):1056-62. doi: 10.1038/ejhg.2009.4. Epub 2009 Feb 11. Eur J Hum Genet. 2009. PMID: 19209188 Free PMC article.
New insights in the molecular pathogenesis of the maternally inherited diabetes and deafness syndrome.
Maassen JA, Jahangir Tafrechi RS, Janssen GM, Raap AK, Lemkes HH, 't Hart LM. Maassen JA, et al. Endocrinol Metab Clin North Am. 2006 Jun;35(2):385-96, x-xi. doi: 10.1016/j.ecl.2006.02.014. Endocrinol Metab Clin North Am. 2006. PMID: 16632100 Review.
Molecular mechanisms of mitochondrial diabetes (MIDD).
Maassen JA, Janssen GM, 't Hart LM. Maassen JA, et al. Ann Med. 2005;37(3):213-21. doi: 10.1080/07853890510007188. Ann Med. 2005. PMID: 16019720 Review.
Evidence that the mitochondrial leucyl tRNA synthetase (LARS2) gene represents a novel type 2 diabetes susceptibility gene.
't Hart LM, Hansen T, Rietveld I, Dekker JM, Nijpels G, Janssen GM, Arp PA, Uitterlinden AG, Jørgensen T, Borch-Johnsen K, Pols HA, Pedersen O, van Duijn CM, Heine RJ, Maassen JA. 't Hart LM, et al. Diabetes. 2005 Jun;54(6):1892-5. doi: 10.2337/diabetes.54.6.1892. Diabetes. 2005. PMID: 15919814
Mitochondrial diabetes: molecular mechanisms and clinical presentation.
Maassen JA, 'T Hart LM, Van Essen E, Heine RJ, Nijpels G, Jahangir Tafrechi RS, Raap AK, Janssen GM, Lemkes HH. Maassen JA, et al. Diabetes. 2004 Feb;53 Suppl 1:S103-9. doi: 10.2337/diabetes.53.2007.s103. Diabetes. 2004. PMID: 14749274 Review.
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