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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2007 2
2008 4
2009 7
2010 5
2011 7
2012 8
2013 5
2014 10
2015 15
2016 12
2017 14
2018 20
2019 15
2020 14
2021 15
2022 4
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142 results
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Page 1
Computational Analysis of Cytokine Release Following Bispecific T-Cell Engager Therapy: Applications of a Logic-Based Model.
Selvaggio G, Parolo S, Bora P, Leonardelli L, Harrold J, Mehta K, Rock DA, Marchetti L. Selvaggio G, et al. Front Oncol. 2022 Mar 8;12:818641. doi: 10.3389/fonc.2022.818641. eCollection 2022. Front Oncol. 2022. PMID: 35350575 Free PMC article.
The use of suitable exogenous intervention strategies to mitigate the CRS risk without compromising the antitumoral capability of bispecific antibody treatment is crucial. To this end, computational approaches can be instrumental to systematically exploring the effects of …
The use of suitable exogenous intervention strategies to mitigate the CRS risk without compromising the antitumoral capability of bispecific …
An age-dependent mathematical model of neurofilament trafficking in healthy conditions.
Paris A, Bora P, Parolo S, Monine M, Tong X, Eraly S, Masson E, Ferguson T, McCampbell A, Graham D, Domenici E, Nestorov I, Marchetti L. Paris A, et al. CPT Pharmacometrics Syst Pharmacol. 2022 Apr;11(4):447-457. doi: 10.1002/psp4.12770. Epub 2022 Mar 2. CPT Pharmacometrics Syst Pharmacol. 2022. PMID: 35146969 Free PMC article.
A Novel Hybrid Logic-ODE Modeling Approach to Overcome Knowledge Gaps.
Selvaggio G, Cristellon S, Marchetti L. Selvaggio G, et al. Front Mol Biosci. 2021 Dec 20;8:760077. doi: 10.3389/fmolb.2021.760077. eCollection 2021. Front Mol Biosci. 2021. PMID: 34988115 Free PMC article.
Furthermore, quantitative formalisms must cope with stiffness and tractability problems, more so if used to describe multicellular systems. On the other hand, qualitative models may lack the proper granularity to describe the underlying kinetic processes. ...
Furthermore, quantitative formalisms must cope with stiffness and tractability problems, more so if used to describe multicellular system
Literature Mining and Mechanistic Graphical Modelling to Improve mRNA Vaccine Platforms.
Leonardelli L, Lofano G, Selvaggio G, Parolo S, Giampiccolo S, Tomasoni D, Domenici E, Priami C, Song H, Medini D, Marchetti L, Siena E. Leonardelli L, et al. Front Immunol. 2021 Sep 7;12:738388. doi: 10.3389/fimmu.2021.738388. eCollection 2021. Front Immunol. 2021. PMID: 34557200 Free PMC article. Review.
While preclinical testing has provided some key insights on how RNA vaccines interact with the innate immune system, their mechanism of action appears to be fragmented amid the literature, making it difficult to formulate new hypotheses to be tested in clinical settings and ultim …
While preclinical testing has provided some key insights on how RNA vaccines interact with the innate immune system, their mechanism of acti …
Reconstruction of the Cytokine Signaling in Lysosomal Storage Diseases by Literature Mining and Network Analysis.
Parolo S, Tomasoni D, Bora P, Ramponi A, Kaddi C, Azer K, Domenici E, Neves-Zaph S, Lombardo R. Parolo S, et al. Front Cell Dev Biol. 2021 Aug 20;9:703489. doi: 10.3389/fcell.2021.703489. eCollection 2021. Front Cell Dev Biol. 2021. PMID: 34490253 Free PMC article.
However, the molecular mechanisms involved in the inflammatory response are still not completely understood. In this study, we performed text-mining and systems biology analyses to investigate the inflammatory signals in three LSDs characterized by sphingolipid accu …
However, the molecular mechanisms involved in the inflammatory response are still not completely understood. In this study, we performed tex …
142 results